<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Flagellate dermatitis represents a unique cutaneous eruption associated with several causes, including treatment with certain chemotherapeutic agents, ingestion of toxins and rheumatologic conditions like adult-onset Still’s disease and dermatomyositis. We present the case of a 35-year-old woman with stage IIA Hodgkin lymphoma who was treated with the ABVD chemotherapy regimen (doxorubicin, bleomycin, vinblastine and dacarbazine). During the third cycle of chemotherapy, she developed multiple linear erythematous macules and hyperpigmentation in a striking flagellate-like pattern localized on the upper chest, submammary folds, neck and upper part of the back. The lesions resolved completely within three months after the withdrawal of bleomycin. Clinicians should be aware of this distinctive cutaneous toxicity in patients receiving bleomycin combination chemotherapy.</p></abstract>

Flagellate dermatitis represents a unique cutaneous eruption associated with several causes, including treatment with certain chemotherapeutic agents, ingestion of toxins and rheumatologic conditions like adult-onset Still’s disease and dermatomyositis. We present the case of a 35-year-old woman with stage IIA Hodgkin lymphoma who was treated with the ABVD chemotherapy regimen (doxorubicin, bleomycin, vinblastine and dacarbazine). During the third cycle of chemotherapy, she developed multiple linear erythematous macules and hyperpigmentation in a striking flagellate-like pattern localized on the upper chest, submammary folds, neck and upper part of the back. The lesions resolved completely within three months after the withdrawal of bleomycin. Clinicians should be aware of this distinctive cutaneous toxicity in patients receiving bleomycin combination chemotherapy.

Bleomycin-induced Flagellate Dermatitis: a Case Report

Department of Medicine, Section of Dermatology

Serbian Journal of Dermatology and Venereology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Bleomycin-induced Flagellate Dermatitis: a Case Report"}

Flagellate dermatitis represents a unique cutaneous eruption associated with several causes, including treatment with certain chemotherapeutic agents,...

Bleomycin-induced Flagellate Dermatitis: a Case Report

Published Online: Sep 22, 2020

Page range: 15 - 18

Received: Jan 16, 2020

Accepted: Mar 31, 2020

DOI: https://doi.org/10.2478/sjdv-2020-0003

Keywords
Bleomycin, Drug-Related Side Effects and Adverse Reactions, Erythema, Antineoplastic Combined Chemo-therapy Protocols, Hodgkin Disease, Hyperpigmentation

© 2020 Beatrice Tonin et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Bleomycin-induced Flagellate Dermatitis: a Case Report

Published Online: Sep 22, 2020

Page range: 15 - 18

Received: Jan 16, 2020

Accepted: Mar 31, 2020

DOI: https://doi.org/10.2478/sjdv-2020-0003

KeywordsBleomycin, Drug-Related Side Effects and Adverse Reactions, Erythema, Antineoplastic Combined Chemo-therapy Protocols, Hodgkin Disease, Hyperpigmentation

© 2020 Beatrice Tonin et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
Bleomycin, Drug-Related Side Effects and Adverse Reactions, Erythema, Antineoplastic Combined Chemo-therapy Protocols, Hodgkin Disease, Hyperpigmentation