The right to life includes the absolute freedom of the individual to live without being endangered or threatened, in conditions of freedom and promotion of interpersonal values. The purpose of the paper is to provide a general overview of the right to life, including the consequences of denying this right, as well as the main forms or distinguishing investigative characteristics in determining whether it is a case of murder or suicide. To provide the required data, a statistical method was used, through which the frequency of murder and suicide during the years 2019-2022 was presented. The comparative method was used to compare the findings on the change in number in relation to the prevalence of murders and suicides. The interview method was used to collect data on the prevalence of murders and suicides at the local level, as well as to determine the distinctive investigative features of these cases. The results of the research indicate that murder, aggravated murder and suicide have been decreased during the period 2019-2022, respectively the first six months of 2022. The results also indicate that investigators may face some difficulties such as the lack of cooperation of witnesses, the unintentional and intentional destruction of evidence, the movement of the victim’s body by changing its position, or even in some cases the lack of professionalism of the investigator. Based on the results, the investigators can distinguish whether it is a case of murder or suicide based on the position of the victim, the type of caused wound, bodily secretions, the past of the victim and the presence of a weapon at the scene. Investigators do not often face doubts as to whether the case is murder or suicide due to sufficient evidence. The research indicates that in some cases the investigators can also face those situations when the murder is staged with manipulative methods to look like suicide.