<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec>
<h3>Background</h3>
<p>To analyze the value of real-time shear wave elastography (SWE) multi-point measurement in the evaluation of muscle elasticity in patients with end-stage renal disease (ESRD) complicated with sarcopenia.</p>
</sec>
<sec>
<h3>Methods</h3>
<p>We enrolled 169 ESRD patients treated as the research objects from January 2019 to February 2022. According to whether they were complicated with sarcopenia, the patients were divided into sarcopenia group (n=63) and non-sarcopenia group (n=106). The Young’s modulus and shear wave velocity (SWV) of muscles in relaxed and contracted states were measured by SWE technology in the two groups.</p>
</sec>
<sec>
<h3>Results</h3>
<p>Logistic regression analysis showed that age and hs-CRP were independent risk factors for sarcopenia in ESRD patients (P&lt;0.05), while BMI, muscle thickness, Young’s modulus in stretched state and SWV in stretched state were protective factors for sarcopenia in ESRD patients (P&lt;0.05). BMI, muscle thickness, Young’s modulus in extended state, SWV in extended state and Young’s modulus in rest state were all negatively correlated with age and hs-CRP (P&lt;0.05), while there was a significant positive correlation between age and hs-CRP (P&lt;0.05). Independent influencing factors were used to construct the prediction model of nomogram. The consistency index (C-index) was 0.845 (95% CI: 0.830~0.857), and the AUC of ROC curve was 0.852 (95% CI: 0.836~0.871), which had good discrimination.</p>
</sec>
<sec>
<h3>Conclusion</h3>
<p>SWE could accurately evaluate the muscle elasticity of ESRD patients, so as to reflect the changes of muscle mass and stiffness of patients, and could provide the important imaging indicator for the prediction of sarcopenia.</p>
</sec>
</abstract>

Background
To analyze the value of real-time shear wave elastography (SWE) multi-point measurement in the evaluation of muscle elasticity in patients with end-stage renal disease (ESRD) complicated with sarcopenia.


Methods
We enrolled 169 ESRD patients treated as the research objects from January 2019 to February 2022. According to whether they were complicated with sarcopenia, the patients were divided into sarcopenia group (n=63) and non-sarcopenia group (n=106). The Young’s modulus and shear wave velocity (SWV) of muscles in relaxed and contracted states were measured by SWE technology in the two groups.


Results
Logistic regression analysis showed that age and hs-CRP were independent risk factors for sarcopenia in ESRD patients (P<0.05), while BMI, muscle thickness, Young’s modulus in stretched state and SWV in stretched state were protective factors for sarcopenia in ESRD patients (P<0.05). BMI, muscle thickness, Young’s modulus in extended state, SWV in extended state and Young’s modulus in rest state were all negatively correlated with age and hs-CRP (P<0.05), while there was a significant positive correlation between age and hs-CRP (P<0.05). Independent influencing factors were used to construct the prediction model of nomogram. The consistency index (C-index) was 0.845 (95% CI: 0.830~0.857), and the AUC of ROC curve was 0.852 (95% CI: 0.836~0.871), which had good discrimination.


Conclusion
SWE could accurately evaluate the muscle elasticity of ESRD patients, so as to reflect the changes of muscle mass and stiffness of patients, and could provide the important imaging indicator for the prediction of sarcopenia.

Evaluation of muscle elasticity in patients with end-stage renal disease complicated with sarcopenia by real-time shear wave elastography multipoint measurement

Revista Romana de Medicina de Laborator

This work is licensed under the Creative Commons Attribution 4.0 International License.

Background
To analyze the value of real-time shear wave elastography (SWE) multi-point measurement in the evaluation of muscle elasticity in patients with...

Evaluation of muscle elasticity in patients with end-stage renal disease complicated with sarcopenia by real-time shear wave elastography multipoint measurement

Article Category: Research Article

Published Online: May 04, 2023

Page range: 135 - 144

Received: Nov 01, 2022

Accepted: Feb 27, 2023

DOI: https://doi.org/10.2478/rrlm-2023-0008

Keywords
real-time shear wave elastography, end-stage renal disease, elasticity of muscle, nomogram

© 2023 Li Guo et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Evaluation of muscle elasticity in patients with end-stage renal disease complicated with sarcopenia by real-time shear wave elastography multipoint measurement

Article Category: Research Article

Published Online: May 04, 2023

Page range: 135 - 144

Received: Nov 01, 2022

Accepted: Feb 27, 2023

DOI: https://doi.org/10.2478/rrlm-2023-0008

Keywordsreal-time shear wave elastography, end-stage renal disease, elasticity of muscle, nomogram

© 2023 Li Guo et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
real-time shear wave elastography, end-stage renal disease, elasticity of muscle, nomogram