[1. Büyükgebiz A. Newborn screening for congenital hypothyroidism. J Clin Res Pediatr Endocrinol. 2013;5 Suppl 1:8-12]Search in Google Scholar
[2. Rastogi MV, LaFranchi SH. Congenital hypothyroidism. Orphanet J Rare Dis. 2010;5:17. DOI: 10.1186/1750-1172-5-1710.1186/1750-1172-5-17290352420537182]Open DOISearch in Google Scholar
[3. Gaudino R, Garel C, Czernichow P, Léger J. Proportion of various types of thyroid disorders among newborns with congenital hypothyroidism and normally located gland: a regional cohort study. Clin Endocrinol (Oxf). 2005;62(4):444-8. DOI: 10.1111/j.1365-2265.2005.02239.x10.1111/j.1365-2265.2005.02239.x15807875]Search in Google Scholar
[4. Anastasovska V, Koviloska R, Kocova M. High incidence of congenital hypothyroidism in one region of the Republic of Macedonia. Balkan J Med Genet. 2014;17(1):31-6. DOI: 10.2478/bjmg-2014-002410.2478/bjmg-2014-0024434747425741212]Open DOISearch in Google Scholar
[5. Kara C, Günindi F, Can Yılmaz G, Aydın M. Transient congenital hypothyroidism in Turkey: an analysis on frequency and natural course. J Clin Res Pediatr Endocrinol. 2016;8(2):170-9. DOI: 10.4274/jcrpe.234510.4274/jcrpe.2345509647227086592]Open DOISearch in Google Scholar
[6. Grasberger H, Refetoff S. Genetic causes of congenital hypothyroidism due to dyshormonogenesis. Curr Opin Pediatr. 2011;23(4):421-8. DOI: 10.1097/MOP.0b013e32834726a410.1097/MOP.0b013e32834726a4326331921543982]Search in Google Scholar
[7. Senese R, Cioffi F, de Lange P, Goglia F, Lanni A. Thyroid: biological actions of ‘nonclassical’ thyroid hormones. J Endocrinol. 2014;221(2):R1-12. DOI: 10.1530/JOE-13-057310.1530/JOE-13-057324464019]Open DOISearch in Google Scholar
[8. Gnidehou S, Caillou B, Talbot M, Ohayon R, Kaniewski J, Noël-Hudson MS, et al. Iodotyrosine dehalogenase 1 (DEHAL1) is a transmembrane protein involved in the recycling of iodide close to the thyroglobulin iodination site. FASEB J. 2004;18(13):1574-6. DOI: 10.1096/fj.04-2023fje10.1096/fj.04-2023fje15289438]Search in Google Scholar
[9. Maia AL, Goemann IM, Meyer EL, Wajner SM. Deiodinases: the balance of thyroid hormone: type 1 iodothyronine deiodinase in human physiology and disease. J Endocrinol. 2011;209(3):283-97. DOI: 10.1530/JOE-10-048110.1530/JOE-10-048121415143]Open DOISearch in Google Scholar
[10. Bianco AC, Kim BW. Deiodinases: implications of the local control of thyroid hormone action. J Clin Invest. 2006;116(10):2571-9. DOI: 10.1172/JCI2981210.1172/JCI29812157859917016550]Search in Google Scholar
[11. Dentice M, Salvatore D. Deiodinases: the balance of thyroid hormone: local impact of thyroid hormone inactivation. J Endocrinol. 2011;209(3):273-82. DOI: 10.1530/JOE-11-000210.1530/JOE-11-000221398344]Open DOISearch in Google Scholar
[12. Arrojo E Drigo R, Bianco AC. Type 2 deiodinase at the crossroads of thyroid hormone action. Int J Biochem Cell Biol. 2011;43(10):1432-4. DOI: 10.1016/j.biocel.2011.05.01610.1016/j.biocel.2011.05.016316377921679772]Search in Google Scholar
[13. Arrojo E Drigo R, Fonseca TL, Werneck-de-Castro JP, Bianco AC. Role of the type 2 iodothyronine deiodinase (D2) in the control of thyroid hormone signalling. Biochim Biophys Acta. 2013;1830(7):3956-64. DOI: 10.1016/j.bbagen.2012.08.01910.1016/j.bbagen.2012.08.019497922622967761]Open DOISearch in Google Scholar
[14. Dentice M, Marsili A, Zavacki A, Larsen PR, Salvatore D. The deiodinases and the control of intracellular thyroid hormone signaling during cellular differentiation. Biochim Biophys Acta. 2013;1830(7):3937-45. DOI: 10.1016/j.bbagen.2012.05.00710.1016/j.bbagen.2012.05.007367067222634734]Open DOISearch in Google Scholar
[15. Alina B, Daria P, Olga F, Vladislav S, Anna K, Elena G. Thr92Ala polymorphism of human type 2 deiodinase gene (hD2) affects the development of Graves’ disease, treatment efficiency, and rate of remission. Clin Dev Immunol. 2012;2012:340542. DOI: 10.1155/2012/34054210.1155/2012/340542350284023193417]Open DOISearch in Google Scholar
[16. Verloop H, Dekkers OM, Peeters RP1, Schoones JW, Smit JW. Genetics in endocrinology: genetic variation in deiodinases: a systematic review of potential clinical effects in humans, Eur J Endocrinol. 2014;171(3):R123-35. DOI: 10.1530/EJE-14-030210.1530/EJE-14-030224878678]Open DOISearch in Google Scholar
[17. McAninch EA, Jo S, Preite NZ, Farkas E, Mohácsik P, Fekete C, et al. Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes. J Clin Endocrinol Metab. 2015;100(3):920-33. DOI: 10.1210/jc.2014-409210.1210/jc.2014-4092433304825569702]Open DOISearch in Google Scholar
[18. Dilli D, Çzbaş S, Acıcan D, Yamak N, Ertek M, Dilmen U. Establishment and development of a national newborn screening programme for congenital hypothyroidism in Turkey. J Clin Res Pediatr Endocrinol. 2013;5(2):73-9. DOI: 10.4274/Jcrpe.92910.4274/Jcrpe.929370192523748057]Open DOISearch in Google Scholar
[19. Carlé A, Faber J, Steffensen R, Laurberg P, Nygaard B. Hypothyroid Patients Encoding Combined MCT10 and DIO2 Gene Polymorphisms May Prefer L-T3 + L-T4 Combination Treatment Data Using a Blind, Randomized, Clinical Study. Eur Thyroid J. 2017;6(3):143-151. DOI: 10.1159/00046970910.1159/000469709552722428785541]Search in Google Scholar
[20. Oto Y, Muroya K, Hanakawa J, Asakura Y, Adachi M. The ratio of serum free triiodothyronine to free thyroxine in children: a retrospective database survey of healthy short individuals and patients with severe thyroid hypoplasia or central hypothyroidism. Thyroid Res. 2015;8:10. DOI: 10.1186/s13044-015-0023-510.1186/s13044-015-0023-5449564426157488]Open DOISearch in Google Scholar
[21. Butler PW, Smith SM, Linderman JD, Brychta RJ, Alberobello AT, Dubaz OM, et al. The Thr92Ala 5’ type 2 deiodinase gene polymorphism is associated with a delayed triiodothyronine secretion in response to the thyrotropin-releasing hormone-stimulation test: a pharmacogenomic study. Thyroid. 2010;20(12):1407-12. DOI: 10.1089/thy.2010.024410.1089/thy.2010.0244299028021054208]Open DOISearch in Google Scholar
[22. Wartofsky L. Combination L-T3 and L-T4 therapy for hypothyroidism., Curr Opin Endocrinol Diabetes Obes. 2013;20(5):460-6. DOI: 10.1097/01.med.0000432611.03732.4910.1097/01.med.0000432611.03732.4923974776]Open DOISearch in Google Scholar
[23. Simionescu R, Cherecheanu A, Voinea L, Sfrenț-Cornățeanu R. TNF-α Gene Polymorphisms and Primary Open Angle Glaucoma in Romanian Population. Rev Romana Med Lab. 2015; 23(1): 47-58. DOI: 10.1515/rrlm-2015-000410.1515/rrlm-2015-0004]Open DOISearch in Google Scholar
[24. Anghel A, Enache A, Seclaman E, Gruin G, Ursoniu S, Alexa A, et al. Genetic polymorphism data on 15 autosomal STR markers in a Western Romanian population sample. Leg Med (Tokyo). 2014;16(4):238-40. DOI: 10.1016/j.legalmed.2014.04.00110.1016/j.legalmed.2014.04.00124767967]Open DOISearch in Google Scholar
[25. Appelhof BC, Peeters RP, Wiersinga WM, Visser TJ, Wekking EM, Huyser J, et al. Polymorphisms in type 2 deiodinase are not associated with well-being, neurocognitive functioning, and preference for combined thyroxine/3,5,3’-triiodothyronine therapy. J Clin Endocrinol Metab. 2005;90(11):6296-9. DOI: 10.1210/jc.2005-045110.1210/jc.2005-045116144953]Open DOISearch in Google Scholar
[26. Peeters RP, van Toor H, Klootwijk W, de Rijke YB, Kuiper GG, Uitterlinden AG, et al. Polymorphisms in thyroid hormone pathway genes are associated with plasma TSH and iodothyronine levels in healthy subjects. J Clin Endocrinol Metab. 2003;88(6):2880-8. DOI: 10.1210/jc.2002-02159210.1210/jc.2002-02159212788902]Search in Google Scholar
[27. Torlontano M, Durante C, Torrente I, Crocetti U, Augello G, Ronga G, et al. Type 2 deiodinase polymorphism (threonine 92 alanine) predicts L-thyroxine dose to achieve target thyrotropin levels in thyroidectomized patients. J Clin Endocrinol Metab. 2008;93(3):910-3. DOI: 10.1210/jc.2007-106710.1210/jc.2007-106718073314]Open DOISearch in Google Scholar
[28. Peeters RP, van den Beld AW, Attalki H, Toor Hv, de Rijke YB, Kuiper GG, et al. A new polymorphism in the type II deiodinase gene is associated with circulating thyroid hormone parameters. Am J Physiol Endocrinol Metab. 2005;289:E75–E81 DOI: 10.1152/ajpendo.00571.200410.1152/ajpendo.00571.200415727947]Open DOISearch in Google Scholar
[29. Bernal J. Thyroid Hormones in Brain Development and Function. De Groot LJ, Chrousos G, Dungan K, et al., editors. Endotext (Internet). South Dartmouth (MA): MDText.com, Inc.; 2000. https://www.ncbi.nlm.nih.gov/books/NBK285549/ (Updated 2015 Sep 2).]Search in Google Scholar
[30. Panicker V, Saravanan P, Vaidya B, Evans J, Hattersley AT, Frayling TM, et al. Common variation in the DIO2 gene predicts baseline psychological well-being and response to combination thyroxine plus triiodothyronine therapy in hypothyroid patients. J Clin Endocrinol Metab. 2009;94(5):1623-9. DOI: 10.1210/jc.2008-130110.1210/jc.2008-130119190113]Open DOISearch in Google Scholar
[31. McDermott MT. Does combination T4 and T3 therapy make sense?, Endocr Pract. 2012;18(5):750-7. DOI: 10.4158/EP12076.RA10.4158/EP12076.RA22548953]Open DOISearch in Google Scholar
[32. Korkmaz L, Akın MA, Güneş T, Daar G, Baştuğ O, Yıkılmaz A, et al. Unusual course of congenital hypothyroidism and route of the L-thyroxine treatment in a preterm newborn. J Clin Res Pediatr Endocrinol. 2014;6(3):177-9. DOI: 10.4274/jcrpe.138310.4274/jcrpe.1383429364825241613]Open DOISearch in Google Scholar
[33. Wiersinga WM, Duntas L, Fadeyev V, Nygaard B, Vanderpump MP. 2012 ETA Guidelines: The Use of L-T4 + L-T3 in the Treatment of Hypothyroidism, Eur Thyroid J. 2012;1(2):55-71. DOI: 10.1159/00033944410.1159/000339444382146724782999]Open DOISearch in Google Scholar
[34. Fisher DA, Schoen EJ, La Franchi S, Mandel SH, Nelson JC, Carlton EI, et al. The hypothalamic-pituitary-thyroid negative feedback control axis in children with treated congenital hypothyroidism. J Clin Endocrinol Metab. 2000;85(8):2722-7. DOI: 10.1210/jcem.85.8.671810.1210/jcem.85.8.671810946871]Search in Google Scholar
[35. Kempers MJ, van Trotsenburg AS, van Tijn DA, Bakker E, Wiedijk BM, Endert E, et al. Disturbance of the fetal thyroid hormone state has long-term consequences for treatment of thyroidal and central congenital hypothyroidism. J Clin Endocrinol Metab. 2005;90(7):4094100. DOI: 10.1210/jc.2005-019710.1210/jc.2005-019715827096]Open DOISearch in Google Scholar
[36. van Mullem AA, Visser TJ, Peeters RP. Clinical Consequences of Mutations in Thyroid Hormone Receptor-α1. Eur Thyroid J. 2014; 3(1): 17–24. DOI: 10.1159/00036063710.1159/000360637400526424847461]Open DOISearch in Google Scholar
[37. Wiersinga WM. Therapy of endocrine disease: T4+T3 combination therapy: is there a true effect?. Eur J Endocrinol. 2017;177(6):R287-R296. DOI: 10.1530/EJE-17-064510.1530/EJE-17-064528855267]Open DOISearch in Google Scholar
[38. Biondi B, Wartofsky L. Combination treatment with T4 and T3: toward personalized replacement therapy in hypothyroidism?. J Clin Endocrinol Metab. 2012;97(7):2256-71. DOI: 10.1210/jc.2011-339910.1210/jc.2011-339922593590]Open DOISearch in Google Scholar