<abstract xmlns="http://www.w3.org/1999/xhtml">
<sec><h3>Introduction:</h3>
<p>Chronic kidney disease (CKD) has always been a complicated global challenge, ranking as the 12th leading cause of death worldwide. Hemodialysis, being one of the most opted renal replacement therapies (RRTs) for patients with end-stage renal disease (ESRD), still possesses some limitations in preventing complications, such as malnutrition and mineral bone disease (CKD-MBD). While efforts have focused on controlling CKD-MBD parameters like calcium and phosphate, less attention has been given to dietary interventions. Moreover, the adoption of low-phosphorus diets for hemodialysis patients is very complex due to potential conflicts with the guideline-recommended high-protein dietary approach. This study sought to investigate the relationship between dietary phosphorus intake and nutritional status in CKD patients undergoing regular hemodialysis.</p>
</sec>
<sec><h3>Method:</h3>
<p>This non-randomized cross-sectional study comprising 88 patients was conducted at the Hemodialysis Unit, RSUD Dr. Soetomo, Surabaya, East Java, using a three-day dietary record in March 2022. Relationships between variables were analyzed using Spearman and ANOVA tests.</p>
</sec>
<sec><h3>Result:</h3>
<p>No significant positive association was found between dietary calcium with corrected calcium levels (p = 0.988; r<sub>s</sub> = −0.002) and between dietary phosphorus with plasma phosphate levels (p = 0.082; r<sub>s</sub> = 0.187). However, Spearman's analysis revealed a weak but positive correlation between dietary phosphorus and nutritional status (p = 0.022; r<sub>s</sub> = 0.215*).</p>
</sec>
<sec><h3>Conclusion:</h3>
<p>Our study highlights a positive relationship between dietary phosphorus and nutritional status among hemodialysis patients, offering insights into potential strategies for optimizing patient care and outcomes.</p>
</sec>
</abstract>

Introduction:
Chronic kidney disease (CKD) has always been a complicated global challenge, ranking as the 12th leading cause of death worldwide. Hemodialysis, being one of the most opted renal replacement therapies (RRTs) for patients with end-stage renal disease (ESRD), still possesses some limitations in preventing complications, such as malnutrition and mineral bone disease (CKD-MBD). While efforts have focused on controlling CKD-MBD parameters like calcium and phosphate, less attention has been given to dietary interventions. Moreover, the adoption of low-phosphorus diets for hemodialysis patients is very complex due to potential conflicts with the guideline-recommended high-protein dietary approach. This study sought to investigate the relationship between dietary phosphorus intake and nutritional status in CKD patients undergoing regular hemodialysis.

Method:
This non-randomized cross-sectional study comprising 88 patients was conducted at the Hemodialysis Unit, RSUD Dr. Soetomo, Surabaya, East Java, using a three-day dietary record in March 2022. Relationships between variables were analyzed using Spearman and ANOVA tests.

Result:
No significant positive association was found between dietary calcium with corrected calcium levels (p = 0.988; rs = −0.002) and between dietary phosphorus with plasma phosphate levels (p = 0.082; rs = 0.187). However, Spearman's analysis revealed a weak but positive correlation between dietary phosphorus and nutritional status (p = 0.022; rs = 0.215*).

Conclusion:
Our study highlights a positive relationship between dietary phosphorus and nutritional status among hemodialysis patients, offering insights into potential strategies for optimizing patient care and outcomes.

The hidden and complex relationship between dietary phosphorus and malnutrition in hemodialysis patients with chronic kidney disease

Department of Internal Medicine, Faculty of Medicine

Department of Orthopedics and Traumatology, Faculty of Medicine

Romanian Journal of Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Introduction:
Chronic kidney disease (CKD) has always been a complicated global challenge, ranking as the 12th leading cause of death worldwide. Hemodialysis,...

The hidden and complex relationship between dietary phosphorus and malnutrition in hemodialysis patients with chronic kidney disease

Published Online: Mar 23, 2024

Page range: 52 - 60

Received: Aug 29, 2023

DOI: https://doi.org/10.2478/rjim-2023-0029

Keywords
albumin, chronic kidney disease, mineral-bone disease, diet, nutrition therapy, phosphate

© 2024 Clonia Milla et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The hidden and complex relationship between dietary phosphorus and malnutrition in hemodialysis patients with chronic kidney disease

Published Online: Mar 23, 2024

Page range: 52 - 60

Received: Aug 29, 2023

DOI: https://doi.org/10.2478/rjim-2023-0029

Keywordsalbumin, chronic kidney disease, mineral-bone disease, diet, nutrition therapy, phosphate

© 2024 Clonia Milla et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
albumin, chronic kidney disease, mineral-bone disease, diet, nutrition therapy, phosphate