<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Multiple myeloma is a neoplasm of plasma cells affecting mostly the elderly with incidence peaks between 60 and 70 years. This disease is exceedingly rare in younger people, especially in adults under 30-year-old. Non-secretory multiple myeloma accounts for 1–5% of all cases of multiple myeloma. It is also a rare condition in young adult patients, and only six cases have been reported [1]. We herein describe a rare case of non-secretory myeloma in a 22-year-old male, explaining from chest wall pain, without general manifestation. Plain radiography and CT scans revealed diffuse osteolytic lesion mimicking the Gorham disease. A bone marrow biopsy was conducted, revealing the diagnosis of myeloma.</p></abstract>

Multiple myeloma is a neoplasm of plasma cells affecting mostly the elderly with incidence peaks between 60 and 70 years. This disease is exceedingly rare in younger people, especially in adults under 30-year-old. Non-secretory multiple myeloma accounts for 1–5% of all cases of multiple myeloma. It is also a rare condition in young adult patients, and only six cases have been reported [1]. We herein describe a rare case of non-secretory myeloma in a 22-year-old male, explaining from chest wall pain, without general manifestation. Plain radiography and CT scans revealed diffuse osteolytic lesion mimicking the Gorham disease. A bone marrow biopsy was conducted, revealing the diagnosis of myeloma.

Non-secretory myeloma in young man mimicking the Gorham disease: case report and the literature review

Romanian Journal of Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Multiple myeloma is a neoplasm of plasma cells affecting mostly the elderly with incidence peaks between 60 and 70 years. This disease is exceedingly rare in...

Non-secretory myeloma in young man mimicking the Gorham disease: case report and the literature review

Published Online: Mar 17, 2022

Page range: 77 - 84

Received: May 11, 2021

DOI: https://doi.org/10.2478/rjim-2021-0036

Keywords
multiple myeloma, Gorham disease, young people, non-secretory

© 2022 Hanene Lassoued Ferjani et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Non-secretory myeloma in young man mimicking the Gorham disease: case report and the literature review

Published Online: Mar 17, 2022

Page range: 77 - 84

Received: May 11, 2021

DOI: https://doi.org/10.2478/rjim-2021-0036

Keywordsmultiple myeloma, Gorham disease, young people, non-secretory

© 2022 Hanene Lassoued Ferjani et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
multiple myeloma, Gorham disease, young people, non-secretory