<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Human herpesvirus 8 (HHV8), also known as Kaposi sarcoma-associated herpesvirus (KSHV), is one of the few pathogens recognized as direct carcinogen, being involved in the pathogenesis of Kaposi sarcoma, primary effusion lymphoma and multicentric Castleman disease. KSHV is a relatively recently discovered virus, with still limited possibilities for diagnosis and treatment. Therefore, ongoing studies are trying to answer the main issues related to the management of KSHV infection and its associated diseases. This review updates the current knowledge of the KSHV infection, discussing aspects related to epidemiology, virological features, clinical manifestations, diagnosis and treatment.</p></abstract>

Human herpesvirus 8 (HHV8), also known as Kaposi sarcoma-associated herpesvirus (KSHV), is one of the few pathogens recognized as direct carcinogen, being involved in the pathogenesis of Kaposi sarcoma, primary effusion lymphoma and multicentric Castleman disease. KSHV is a relatively recently discovered virus, with still limited possibilities for diagnosis and treatment. Therefore, ongoing studies are trying to answer the main issues related to the management of KSHV infection and its associated diseases. This review updates the current knowledge of the KSHV infection, discussing aspects related to epidemiology, virological features, clinical manifestations, diagnosis and treatment.

Update on Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) – review

“Carol Davila” University of Medicine and Pharmacy

Romanian Journal of Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Update on Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) \u2013 review"}

Human herpesvirus 8 (HHV8), also known as Kaposi sarcoma-associated herpesvirus (KSHV), is one of the few pathogens recognized as direct carcinogen, being...

Update on Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) – review

Published Online: Dec 17, 2020

Page range: 199 - 208

Received: Jun 10, 2020

DOI: https://doi.org/10.2478/rjim-2020-0017

Keywords
Kaposi sarcoma-associated herpesvirus, KSHV, Kaposi sarcoma, primary effusion lymphoma, multicentric Castleman disease

© 2020 Nicoleta Iftode et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Update on Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) – review

Published Online: Dec 17, 2020

Page range: 199 - 208

Received: Jun 10, 2020

DOI: https://doi.org/10.2478/rjim-2020-0017

KeywordsKaposi sarcoma-associated herpesvirus, KSHV, Kaposi sarcoma, primary effusion lymphoma, multicentric Castleman disease

© 2020 Nicoleta Iftode et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
Kaposi sarcoma-associated herpesvirus, KSHV, Kaposi sarcoma, primary effusion lymphoma, multicentric Castleman disease