<abstract xmlns="http://www.w3.org/1999/xhtml"><bold><italic>Background</italic></bold>. In the last years an uprising interest for a relatively unknown entity, eosinophilic ascites (EA), has been recorded.Our aim is to investigate the potential causes of EA development, as well as clinical, laboratory, endoscopic and radiologic features, management and outcome in these patients.<bold><italic>Methods</italic></bold>. The following research was performed on PubMed (MEDLINE) database using the medical subject headings [Mesh] terms “Ascites” AND “Eosinophils”.<bold><italic>Results</italic></bold>. A total of 284 results, dating from 1962 onwards, were found and abstracts were examined. 131 papers were excluded and the remaining 153 publications, consisting in case reports and series of cases, were analyzed.From 171 patients with EA, 127 subjects (74%) had EGE, 17 (10%) parasitic and fungal infections, 11(7%) Hypereosinophilic syndrome and 16 patients (9%) less common diseases (eosinophilic pancreatitis, chronic eosinophilic leukemia, myelofibrosis, T-cell lymphoma, Churg Strauss Syndrome, Systemic lupus erythematosus, Familial paroxysmal polyserositis and Ménétrier’s disease). High eosinophil blood count and IgE levels as well as gastrointestinal symptoms are frequent. The diagnosis is based on ascitic fluid analysis, imaging and endoscopic biopsies. Therapy with corticosteroids results in resolution of eosinophilic ascites in almost all patients.<bold><italic>Conclusion</italic></bold>. In most cases, in the absence of allergy, parasitic infections, malignancy, hematological disorders, peritoneal tuberculosis, inflammatory bowel disease or autoimmune disease, EA develops as a manifestation of eosinophilic gastroenteritis.</abstract>

Background. In the last years an uprising interest for a relatively unknown entity, eosinophilic ascites (EA), has been recorded.Our aim is to investigate the potential causes of EA development, as well as clinical, laboratory, endoscopic and radiologic features, management and outcome in these patients.Methods. The following research was performed on PubMed (MEDLINE) database using the medical subject headings [Mesh] terms “Ascites” AND “Eosinophils”.Results. A total of 284 results, dating from 1962 onwards, were found and abstracts were examined. 131 papers were excluded and the remaining 153 publications, consisting in case reports and series of cases, were analyzed.From 171 patients with EA, 127 subjects (74%) had EGE, 17 (10%) parasitic and fungal infections, 11(7%) Hypereosinophilic syndrome and 16 patients (9%) less common diseases (eosinophilic pancreatitis, chronic eosinophilic leukemia, myelofibrosis, T-cell lymphoma, Churg Strauss Syndrome, Systemic lupus erythematosus, Familial paroxysmal polyserositis and Ménétrier’s disease). High eosinophil blood count and IgE levels as well as gastrointestinal symptoms are frequent. The diagnosis is based on ascitic fluid analysis, imaging and endoscopic biopsies. Therapy with corticosteroids results in resolution of eosinophilic ascites in almost all patients.Conclusion. In most cases, in the absence of allergy, parasitic infections, malignancy, hematological disorders, peritoneal tuberculosis, inflammatory bowel disease or autoimmune disease, EA develops as a manifestation of eosinophilic gastroenteritis.

Causes of eosinophilic ascites – A systematic review

Internal Medicine Department, “Colentina” Clinical Hospital

Romanian Journal of Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Causes of eosinophilic ascites \u2013 A systematic review"}

Background. In the last years an uprising interest for a relatively unknown entity, eosinophilic ascites (EA), has been recorded.Our aim is to investigate the...

Causes of eosinophilic ascites – A systematic review

Published Online: Jun 20, 2019

Page range: 110 - 124

Received: Dec 12, 2018

DOI: https://doi.org/10.2478/rjim-2018-0041

Keywords
Ascites, Hypereosinophilia, Eosinophilic ascites, Eosinophilic gastroenteritis, Hypereosinophilic syndrome, parasitic infection, systematic review

© 2019 Larisa Pinte et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Causes of eosinophilic ascites – A systematic review

Published Online: Jun 20, 2019

Page range: 110 - 124

Received: Dec 12, 2018

DOI: https://doi.org/10.2478/rjim-2018-0041

KeywordsAscites, Hypereosinophilia, Eosinophilic ascites, Eosinophilic gastroenteritis, Hypereosinophilic syndrome, parasitic infection, systematic review

© 2019 Larisa Pinte et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
Ascites, Hypereosinophilia, Eosinophilic ascites, Eosinophilic gastroenteritis, Hypereosinophilic syndrome, parasitic infection, systematic review