<abstract xmlns="http://www.w3.org/1999/xhtml"><bold><italic>Background and Objective</italic></bold>. Vitamin D deficiency is considered one of the most common nutritional deficiencies associated with weakened immune system and increased likelihood of sepsis. The current study was conducted to investigate the association between serum vitamin D level and the severity and prognosis of ventilator associated pneumonia (VAP) in inpatients in intensive care unit (ICU).<bold><italic>Methods</italic></bold>. Eighty-four consecutive patients with VAP were enrolled in this observational, prospective study conducted in the ICU of Besat Hospital, Hamadan. The patients were examined for serum 25-hydroxyvitamin D (vitD3) level and VAP severity and prognosis. Clinical pulmonary infection score was used for the diagnosis, and Sequential Organ Failure Assessment (SOFA) Score was used to determine the severity of VAP.<bold><italic>Results</italic></bold>. Low level serum vitD3 (under 30 ng/mL) was found in 66 (78.6%) patients. In this series of VAP patients, there were no significant differences in blood culture results, 14 and 28-day sepsis-associated mortality, mechanical ventilation duration, or SOFA Score on days 3, 7, and 14 between the low level and normal level vitD3 patients (<italic>p</italic> > 0.05).<bold><italic>Conclusion</italic></bold>. Serum vitD3 level was not associated with mortality from VAP or complications due to sepsis in the inpatients in the ICU.</abstract>

Background and Objective. Vitamin D deficiency is considered one of the most common nutritional deficiencies associated with weakened immune system and increased likelihood of sepsis. The current study was conducted to investigate the association between serum vitamin D level and the severity and prognosis of ventilator associated pneumonia (VAP) in inpatients in intensive care unit (ICU).Methods. Eighty-four consecutive patients with VAP were enrolled in this observational, prospective study conducted in the ICU of Besat Hospital, Hamadan. The patients were examined for serum 25-hydroxyvitamin D (vitD3) level and VAP severity and prognosis. Clinical pulmonary infection score was used for the diagnosis, and Sequential Organ Failure Assessment (SOFA) Score was used to determine the severity of VAP.Results. Low level serum vitD3 (under 30 ng/mL) was found in 66 (78.6%) patients. In this series of VAP patients, there were no significant differences in blood culture results, 14 and 28-day sepsis-associated mortality, mechanical ventilation duration, or SOFA Score on days 3, 7, and 14 between the low level and normal level vitD3 patients (p > 0.05).Conclusion. Serum vitD3 level was not associated with mortality from VAP or complications due to sepsis in the inpatients in the ICU.

Serum vitamin D level was not associated with severity of ventilator associated pneumonia

Department of Infectious Disease, School of Medicine

Department of Anesthesiology and Critical Care, School of Medicine

Department of Community Medicine, School of Medicine

Romanian Journal of Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Background and Objective. Vitamin D deficiency is considered one of the most common nutritional deficiencies associated with weakened immune system and...

Serum vitamin D level was not associated with severity of ventilator associated pneumonia

Published Online: Mar 28, 2019

Page range: 55 - 60

Received: Aug 19, 2018

DOI: https://doi.org/10.2478/rjim-2018-0033

Keywords
Vitamin D, Pneumonia, Ventilator-Associated

© 2019 Mojtaba Hedayat Yaghoobi et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Serum vitamin D level was not associated with severity of ventilator associated pneumonia

Published Online: Mar 28, 2019

Page range: 55 - 60

Received: Aug 19, 2018

DOI: https://doi.org/10.2478/rjim-2018-0033

KeywordsVitamin D, Pneumonia, Ventilator-Associated

© 2019 Mojtaba Hedayat Yaghoobi et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
Vitamin D, Pneumonia, Ventilator-Associated