<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec>
<h3>Background</h3>
<p>Increased atrial elasticity is a marker of cardiovascular events. This study aimed to compare the parameters of elasticity and lipids in children with type 1 diabetes mellitus (TIDM) compared with controls and the effect of lipids on elasticity in children with diabetes.</p>
</sec>
<sec>
<h3>Method</h3>
<p>This case-control study was performed in 186 children aged 6 to 18 years. The aortic diameter was obtained from 3 cm above the aortic valve using M mode and was calculated as the distance between the medial edge of the anterior and posterior walls of the aorta at systole and diastole. AoS and AoD were recorded when the aortic wall was fully open. The parameters of aortic elasticity, aortic stiffness beta index, aortic tension, and elastic modulus of pressure were measured. Cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein were measured. For data analysis, SPSS 20 considers the applicable error to be 0.05.</p>
</sec>
<sec>
<h3>Results</h3>
<p>The participants were matched by sex and age. The right CHO, LDL, HDL, and MPI lipids, systolic, diastolic, and aortic systolic blood pressure were different among patients. The analysis also showed that ASβI (MWU = 1582.50, <italic>p</italic> &lt; 0.001) and PSEM (MWU = 1381.00 and <italic>p</italic> &lt; 0.001) were higher when AS (MWU = 1204 and <italic>p</italic> &lt; 0.001) and AoD (MWU = 1672.00 and <italic>p</italic> &lt; 0.001) and AoD (MWU = 1672.00 and <italic>p</italic> &lt; 0.001) were lower in patients than in controls. No lipid profiles were significantly correlated with stiffness parameters before and after controlling for age.</p>
</sec>
<sec>
<h3>Conclusion</h3>
<p>It was concluded that lipid profiles were different, and ASβI and PSEM were lower when AoS and AoD were higher in children with diabetes. None of the lipid profiles were significantly correlated with stiffness parameters before and after controlling for age.</p>
</sec>
</abstract>

Background
Increased atrial elasticity is a marker of cardiovascular events. This study aimed to compare the parameters of elasticity and lipids in children with type 1 diabetes mellitus (TIDM) compared with controls and the effect of lipids on elasticity in children with diabetes.


Method
This case-control study was performed in 186 children aged 6 to 18 years. The aortic diameter was obtained from 3 cm above the aortic valve using M mode and was calculated as the distance between the medial edge of the anterior and posterior walls of the aorta at systole and diastole. AoS and AoD were recorded when the aortic wall was fully open. The parameters of aortic elasticity, aortic stiffness beta index, aortic tension, and elastic modulus of pressure were measured. Cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein were measured. For data analysis, SPSS 20 considers the applicable error to be 0.05.


Results
The participants were matched by sex and age. The right CHO, LDL, HDL, and MPI lipids, systolic, diastolic, and aortic systolic blood pressure were different among patients. The analysis also showed that ASβI (MWU = 1582.50, p < 0.001) and PSEM (MWU = 1381.00 and p < 0.001) were higher when AS (MWU = 1204 and p < 0.001) and AoD (MWU = 1672.00 and p < 0.001) and AoD (MWU = 1672.00 and p < 0.001) were lower in patients than in controls. No lipid profiles were significantly correlated with stiffness parameters before and after controlling for age.


Conclusion
It was concluded that lipid profiles were different, and ASβI and PSEM were lower when AoS and AoD were higher in children with diabetes. None of the lipid profiles were significantly correlated with stiffness parameters before and after controlling for age.

Elasticity and Lipids Changes in Children with Type I Diabetes Mellitus Compared with Controls and the Effect of Lipids on Elasticity in Diabetic Children

Romanian Journal of Cardiology

This work is licensed under the Creative Commons Attribution 4.0 International License.

Background
Increased atrial elasticity is a marker of cardiovascular events. This study aimed to compare the parameters of elasticity and lipids in children...

Elasticity and Lipids Changes in Children with Type I Diabetes Mellitus Compared with Controls and the Effect of Lipids on Elasticity in Diabetic Children

Article Category: Original Article

Published Online: Sep 16, 2023

Page range: 99 - 106

DOI: https://doi.org/10.2478/rjc-2023-0019

Keywords
Aortic Elasticity, lipid, diabetes Type I, children

© 2023 Noor Mohammad Noori et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Elasticity and Lipids Changes in Children with Type I Diabetes Mellitus Compared with Controls and the Effect of Lipids on Elasticity in Diabetic Children

Article Category: Original Article

Published Online: Sep 16, 2023

Page range: 99 - 106

DOI: https://doi.org/10.2478/rjc-2023-0019

KeywordsAortic Elasticity, lipid, diabetes Type I, children

© 2023 Noor Mohammad Noori et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
Aortic Elasticity, lipid, diabetes Type I, children