Quantitative assessment of bone marrow infiltration and characterization of tumor burden using dual-layer spectral CT in patients with multiple myeloma

1. Kazandjian D. Multiple myeloma epidemiology and survival: a unique malignancy. Semin Oncol 2016; 43: 676–81. doi: 10.1053/j.seminoncol.2016.11.004 KazandjianD Multiple myeloma epidemiology and survival: a unique malignancy Semin Oncol 2016 43 676 81 10.1053/j.seminoncol.2016.11.004 Open DOISearch in Google Scholar

2. Panaroni C, Yee AJ, Raje NS. Myeloma and bone disease. Curr Osteoporos Rep 2017; 15: 483–98. doi: 10.1007/s11914-017-0397-5 PanaroniC YeeAJ RajeNS Myeloma and bone disease Curr Osteoporos Rep 2017 15 483 98 10.1007/s11914-017-0397-5 Open DOISearch in Google Scholar

3. O’Donnell EK, Raje NS. Myeloma bone disease: pathogenesis and treatment. Clin Adv Hematol Oncol 2017; 15: 285–95. PMID: 28591104 O’DonnellEK RajeNS Myeloma bone disease: pathogenesis and treatment Clin Adv Hematol Oncol 2017 15 285 95 28591104 Search in Google Scholar

4. Rajkumar SV, Dimopoulos MA, Palumbo A, Blade J, Merlini G, Mateos MV, et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol 2014; 15: e538–48. doi: 10.1016/S1470-2045(14)70442-5 RajkumarSV DimopoulosMA PalumboA BladeJ MerliniG MateosMV International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma Lancet Oncol 2014 15 e538 48 10.1016/S1470-2045(14)70442-5 Open DOISearch in Google Scholar

5. Duvauferrier R, Valence M, Patrat-Delon S, Brillet E, Niederberger E, Marchand A, et al. Current role of CT and whole body MRI in multiple myeloma. Diagn Interv Imaging 2013; 94: 169–83. doi: 10.1016/j.diii.2012.12.001 DuvauferrierR ValenceM Patrat-DelonS BrilletE NiederbergerE MarchandA Current role of CT and whole body MRI in multiple myeloma Diagn Interv Imaging 2013 94 169 83 10.1016/j.diii.2012.12.001 Open DOISearch in Google Scholar

6. Dimopoulos M, Terpos E, Comenzo RL, Tosi P, Beksac M, Sezer O, et al. International Myeloma Working Group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple myeloma. Leukemia 2009; 23: 1545–56. doi: 10.1038/leu.2009.89 DimopoulosM TerposE ComenzoRL TosiP BeksacM SezerO International Myeloma Working Group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple myeloma Leukemia 2009 23 1545 56 10.1038/leu.2009.89 Open DOISearch in Google Scholar

7. Durie BG, Salmon SE. A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. Cancer 1975; 36: 842–54. doi: 10.1002/1097-0142(197509)36:3<842::aid-cncr2820360303>3.0.co;2-u DurieBG SalmonSE A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival Cancer 1975 36 842 54 10.1002/1097-0142(197509)36:3<842::aid-cncr2820360303>3.0.co;2-u Open DOISearch in Google Scholar

8. Portet M, Owens E, Howlett D. The use of whole-body MRI in multiple myeloma. Clin Med 2019; 19: 355–6. doi: 10.7861/clinmedicine.19-4-355 PortetM OwensE HowlettD The use of whole-body MRI in multiple myeloma Clin Med 2019 19 355 6 10.7861/clinmedicine.19-4-355 Open DOISearch in Google Scholar

9. Kosmala A, Weng AM, Heidemeier A, Krauss B, Knop S, Bley TA, et al. Multiple myeloma and dual-energy CT: diagnostic accuracy of virtual non-calcium technique for detection of bone marrow infiltration of the spine and pelvis. Radiology 2018; 286: 205–13. doi: 10.1148/radiol.2017170281 KosmalaA WengAM HeidemeierA KraussB KnopS BleyTA Multiple myeloma and dual-energy CT: diagnostic accuracy of virtual non-calcium technique for detection of bone marrow infiltration of the spine and pelvis Radiology 2018 286 205 13 10.1148/radiol.2017170281 Open DOISearch in Google Scholar

10. Hillengass J, Usmani S, Rajkumar SV, Durie BGM, Mateos MV, Lonial S, et al. International Myeloma Working Group consensus recommendations on imaging in monoclonal plasma cell disorders. Lancet Oncol 2019; 20: e302–e312. doi: 10.1016/S1470-2045(19)30309-2 HillengassJ UsmaniS RajkumarSV DurieBGM MateosMV LonialS International Myeloma Working Group consensus recommendations on imaging in monoclonal plasma cell disorders Lancet Oncol 2019 20 e302 e312 10.1016/S1470-2045(19)30309-2 Open DOISearch in Google Scholar

11. Shah LM, Hanrahan CJ. MRI of spinal bone marrow: part I, techniques and normal age-related appearances. AJR Am J Roentgenol 2011; 197: 1298–308. doi: 10.2214/AJR.11.7005 ShahLM HanrahanCJ MRI of spinal bone marrow: part I, techniques and normal age-related appearances AJR Am J Roentgenol 2011 197 1298 308 10.2214/AJR.11.7005 Open DOISearch in Google Scholar

12. Padhani AR, Koh DM, Collins DJ. Whole-body diffusion-weighted MR imaging in cancer: current status and research directions. Radiology 2011; 261: 700–18. doi: 10.1148/radiol.11110474 PadhaniAR KohDM CollinsDJ Whole-body diffusion-weighted MR imaging in cancer: current status and research directions Radiology 2011 261 700 18 10.1148/radiol.11110474 Open DOISearch in Google Scholar

13. Cavo M, Terpos E, Nanni C, Moreau P, Lentzsch S, Zweegman S, et al. Role of (18)F-FDG PET/CT in the diagnosis and management of multiple myeloma and other plasma cell disorders: a consensus statement by the International Myeloma Working Group. Lancet Oncol 2017; 18: e206–e217. doi: 10.1016/S1470-2045(17)30189-4 CavoM TerposE NanniC MoreauP LentzschS ZweegmanS Role of (18)F-FDG PET/CT in the diagnosis and management of multiple myeloma and other plasma cell disorders: a consensus statement by the International Myeloma Working Group Lancet Oncol 2017 18 e206 e217 10.1016/S1470-2045(17)30189-4 Open DOISearch in Google Scholar

14. Fervers P, Fervers F, Kottlors J, Lohneis P, Pollman-Schweckhorst P, Zaytoun H, et al. Feasibility of artificial intelligence-supported assessment of bone marrow infiltration using dual-energy computed tomography in patients with evidence of monoclonal protein - a retrospective observational study. Eur Radiol 2022; 32: 2901–11. doi: 10.1007/s00330-021-08419-2 FerversP FerversF KottlorsJ LohneisP Pollman-SchweckhorstP ZaytounH Feasibility of artificial intelligence-supported assessment of bone marrow infiltration using dual-energy computed tomography in patients with evidence of monoclonal protein - a retrospective observational study Eur Radiol 2022 32 2901 11 10.1007/s00330-021-08419-2 Open DOISearch in Google Scholar

15. Fervers P, Glauner A, Gertz R, Täger P, Kottlors J, Maintz D, et al. Virtual calcium-suppression in dual energy computed tomography predicts metabolic activity of focal MM lesions as determined by fluorodeoxyglucose positron-emission-tomography. Eur J Radiol 2021; 135: 109502. doi: 10.1016/j.ejrad.2020.109502 FerversP GlaunerA GertzR TägerP KottlorsJ MaintzD Virtual calcium-suppression in dual energy computed tomography predicts metabolic activity of focal MM lesions as determined by fluorodeoxyglucose positron-emission-tomography Eur J Radiol 2021 135 109502 10.1016/j.ejrad.2020.109502 Open DOISearch in Google Scholar

16. Brandelik SC, Skornitzke S, Mokry T, Sauer S, Stiller W, Nattenmüller J, et al. Quantitative and qualitative assessment of plasma cell dyscrasias in dual-layer spectral CT. Eur Radiol 2021; 31: 7664–73. doi: 10.1007/s00330-021-07821-0 BrandelikSC SkornitzkeS MokryT SauerS StillerW NattenmüllerJ Quantitative and qualitative assessment of plasma cell dyscrasias in dual-layer spectral CT Eur Radiol 2021 31 7664 73 10.1007/s00330-021-07821-0 Open DOISearch in Google Scholar

17. Moulopoulos LA, Koutoulidis V, Hillengass J, Zamagni E, Aquerreta JD, Roche CL, et al. Recommendations for acquisition, interpretation and reporting of whole body low dose CT in patients with multiple myeloma and other plasma cell disorders: a report of the IMWG Bone Working Group. Blood Cancer J 2018; 8: 95. doi: 10.1038/s41408-018-0124-1 MoulopoulosLA KoutoulidisV HillengassJ ZamagniE AquerretaJD RocheCL Recommendations for acquisition, interpretation and reporting of whole body low dose CT in patients with multiple myeloma and other plasma cell disorders: a report of the IMWG Bone Working Group Blood Cancer J 2018 8 95 10.1038/s41408-018-0124-1 Open DOISearch in Google Scholar

18. Reinert CP, Krieg E, Esser M, Nikolaou K, Bösmüller H, Horger M. Role of computed tomography texture analysis using dual-energy-based bone marrow imaging for multiple myeloma characterization: comparison with histology and established serologic parameters. Eur Radiol 2021; 31: 2357–67. doi: 10.1007/s00330-020-07320-8 ReinertCP KriegE EsserM NikolaouK BösmüllerH HorgerM Role of computed tomography texture analysis using dual-energy-based bone marrow imaging for multiple myeloma characterization: comparison with histology and established serologic parameters Eur Radiol 2021 31 2357 67 10.1007/s00330-020-07320-8 Open DOISearch in Google Scholar

19. Hu C, Zhang Y, Xiong X, Meng Q, Yao F, Ye A, et al. Quantitative evaluation of bone marrow infiltration using dual-energy spectral computed tomography in patients with multiple myeloma. J Xray Sci Technol 2021; 29: 463–75. doi: 10.3233/XST-200811 HuC ZhangY XiongX MengQ YaoF YeA Quantitative evaluation of bone marrow infiltration using dual-energy spectral computed tomography in patients with multiple myeloma J Xray Sci Technol 2021 29 463 75 10.3233/XST-200811 Open DOISearch in Google Scholar

20. Mosebach J, Thierjung H, Schlemmer HP, Delorme S. Multiple myeloma guidelines and their recent updates: implications for imaging. Rofo 2019; 191: 998–1009. doi: 10.1055/a-0897-3966 MosebachJ ThierjungH SchlemmerHP DelormeS Multiple myeloma guidelines and their recent updates: implications for imaging Rofo 2019 191 998 1009 10.1055/a-0897-3966 Open DOISearch in Google Scholar

21. Cowan AJ, Green DJ, Kwok M, Lee S, Coffey DG, Holmberg LA, et al. Diagnosis and management of multiple myeloma: a review. JAMA 2022; 327: 464–77. doi: 10.1001/jama.2022.0003 CowanAJ GreenDJ KwokM LeeS CoffeyDG HolmbergLA Diagnosis and management of multiple myeloma: a review JAMA 2022 327 464 77 10.1001/jama.2022.0003 Open DOISearch in Google Scholar

22. Thomas C, Schabel C, Krauss B, Weisel K, Bongers M, Claussen CD, et al. Dual-energy CT: virtual calcium subtraction for assessment of bone marrow involvement of the spine in multiple myeloma. AJR Am J Roentgenol 2015; 204: W324–31. doi: 10.2214/AJR.14.12613 ThomasC SchabelC KraussB WeiselK BongersM ClaussenCD Dual-energy CT: virtual calcium subtraction for assessment of bone marrow involvement of the spine in multiple myeloma AJR Am J Roentgenol 2015 204 W324 31 10.2214/AJR.14.12613 Open DOISearch in Google Scholar

23. Ekert K, Hinterleitner C, Baumgartner K, Fritz J, Horger M. Extended texture analysis of non-enhanced whole-body MRI image data for response assessment in multiple myeloma patients undergoing systemic therapy. Cancers 2020; 12: 761. doi: 10.3390/cancers12030761 EkertK HinterleitnerC BaumgartnerK FritzJ HorgerM Extended texture analysis of non-enhanced whole-body MRI image data for response assessment in multiple myeloma patients undergoing systemic therapy Cancers 2020 12 761 10.3390/cancers12030761 Open DOISearch in Google Scholar

24. Yu Z, Leng S, Jorgensen SM, Li Z, Gutjahr R, Chen B, et al. Evaluation of conventional imaging performance in a research whole-body CT system with a photon-counting detector array. Phys Med Biol 2016; 61: 1572–95. doi: 10.1088/0031-9155/61/4/1572 YuZ LengS JorgensenSM LiZ GutjahrR ChenB Evaluation of conventional imaging performance in a research whole-body CT system with a photon-counting detector array Phys Med Biol 2016 61 1572 95 10.1088/0031-9155/61/4/1572 Open DOISearch in Google Scholar

25. Koutoulidis V, Terpos E, Papanikolaou N, Fontara S, Seimenis I, Gavriatopoulou M, et al. Comparison of MRI features of fat fraction and ADC for early treatment response assessment in participants with multiple myeloma. Radiology 2022; 304: 137–44. doi: 10.1148/radiol.211388 KoutoulidisV TerposE PapanikolaouN FontaraS SeimenisI GavriatopoulouM Comparison of MRI features of fat fraction and ADC for early treatment response assessment in participants with multiple myeloma Radiology 2022 304 137 44 10.1148/radiol.211388 Open DOISearch in Google Scholar

26. Sidiqi MH, Aljama M, Kumar SK, Jevremovic D, Buadi FK, Warsame R, et al. The role of bone marrow biopsy in patients with plasma cell disorders: should all patients with a monoclonal protein be biopsied? Blood Cancer J 2020; 10: 52. doi: 10.1038/s41408-020-0319-0 SidiqiMH AljamaM KumarSK JevremovicD BuadiFK WarsameR The role of bone marrow biopsy in patients with plasma cell disorders: should all patients with a monoclonal protein be biopsied? Blood Cancer J 2020 10 52 10.1038/s41408-020-0319-0 Open DOISearch in Google Scholar

27. Dupuis MM, Tuchman SA. Non-secretory multiple myeloma: from biology to clinical management. Onco Targets Ther 2016; 9: 7583–90. doi: 10.2147/OTT.S122241 DupuisMM TuchmanSA Non-secretory multiple myeloma: from biology to clinical management Onco Targets Ther 2016 9 7583 90 10.2147/OTT.S122241 Open DOISearch in Google Scholar

28. Wale A, Pawlyn C, Kaiser M, Messiou C. Frequency, distribution and clinical management of incidental findings and extramedullary plasmacytomas in whole body diffusion weighted magnetic resonance imaging in patients with multiple myeloma. Haematologica 2016; 101: e142–4. doi: 10.3324/haematol.2015.139816 WaleA PawlynC KaiserM MessiouC Frequency, distribution and clinical management of incidental findings and extramedullary plasmacytomas in whole body diffusion weighted magnetic resonance imaging in patients with multiple myeloma Haematologica 2016 101 e142 4 10.3324/haematol.2015.139816 Open DOISearch in Google Scholar

29. Hamdaoui H, Benlarroubia O, Ait Boujmia OK, Mossafa H, Ouldim K, Belkhayat A, et al. Cytogenetic and FISH analysis of 93 multiple myeloma Moroccan patients. Mol Genet Genomic Med 2020; 8: e1363. doi: 10.1002/mgg3.1363 HamdaouiH BenlarroubiaO Ait BoujmiaOK MossafaH OuldimK BelkhayatA Cytogenetic and FISH analysis of 93 multiple myeloma Moroccan patients Mol Genet Genomic Med 2020 8 e1363 10.1002/mgg3.1363 Open DOISearch in Google Scholar

30. Saxe D, Seo EJ, Bergeron MB, Han JY. Recent advances in cytogenetic characterization of multiple myeloma. Int J Lab Hematol 2019; 41: 5–14. doi: 10.1111/ijlh.12882 SaxeD SeoEJ BergeronMB HanJY Recent advances in cytogenetic characterization of multiple myeloma Int J Lab Hematol 2019 41 5 14 10.1111/ijlh.12882 Open DOISearch in Google Scholar

31. Zhao XQ, Zhao SY, Chen WX, Liu XW, Yan HX, Lou YJ. Correlation between clinical factors and prognosis in newly diagnosed multiple myeloma. J Coll Physicians Surg Pak 2020; 30: 601–5. doi: 10.29271/jcpsp.2020.06.601 ZhaoXQ ZhaoSY ChenWX LiuXW YanHX LouYJ Correlation between clinical factors and prognosis in newly diagnosed multiple myeloma J Coll Physicians Surg Pak 2020 30 601 5 10.29271/jcpsp.2020.06.601 Open DOISearch in Google Scholar

32. Usmani SZ, Crowley J, Hoering A, Mitchell A, Waheed S, Nair B, et al. Improvement in long-term outcomes with successive total therapy trials for multiple myeloma: are patients now being cured? Leukemia 2013; 27: 226–32. doi: 10.1038/leu.2012.160 UsmaniSZ CrowleyJ HoeringA MitchellA WaheedS NairB Improvement in long-term outcomes with successive total therapy trials for multiple myeloma: are patients now being cured? Leukemia 2013 27 226 32 10.1038/leu.2012.160 Open DOISearch in Google Scholar

33. Ross FM, Avet-Loiseau H, Ameye G, Gutiérrez NC, Liebisch P, O’Connor S, et al. Report from the European Myeloma Network on interphase FISH in multiple myeloma and related disorders. Haematologica 2012; 97: 1272–7. doi: 10.3324/haematol.2011.056176 RossFM Avet-LoiseauH AmeyeG GutiérrezNC LiebischP O’ConnorS Report from the European Myeloma Network on interphase FISH in multiple myeloma and related disorders Haematologica 2012 97 1272 7 10.3324/haematol.2011.056176 Open DOISearch in Google Scholar