<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Background</h3>
<p>Optical coherence tomography angiography (OCTA) is an emerging imaging modality that enables noninvasive visualization and analysis of tumor vasculature. OCTA has been particularly useful in clinical ocular oncology, while in this article, we evaluated OCTA in assessing microvascular changes in clinical nonocular oncology through a systematic review of the literature.</p>
</sec>
<sec><h3>Method</h3>
<p>The inclusion criterion for the literature search in PubMed, Web of Science and Scopus electronic databases was the use of OCTA in nonocular clinical oncology, meaning that all ocular clinical studies and all ocular and nonocular animal, phantom, ex vivo, experimental, research and development, and purely methodological studies were excluded.</p>
</sec>
<sec><h3>Results</h3>
<p>Eleven articles met the inclusion criteria. The anatomic locations of the neoplasms in the selected articles were the gastrointestinal tract (2 articles), head and neck (1 article) and skin (8 articles).</p>
</sec>
<sec><h3>Conclusions</h3>
<p>While OCTA has shown great advancements in ophthalmology, its translation to the nonocular clinical oncology setting presents several limitations, with a lack of standardized protocols and interpretation guidelines posing the most significant challenge.</p>
</sec>
</abstract>

Background
Optical coherence tomography angiography (OCTA) is an emerging imaging modality that enables noninvasive visualization and analysis of tumor vasculature. OCTA has been particularly useful in clinical ocular oncology, while in this article, we evaluated OCTA in assessing microvascular changes in clinical nonocular oncology through a systematic review of the literature.

Method
The inclusion criterion for the literature search in PubMed, Web of Science and Scopus electronic databases was the use of OCTA in nonocular clinical oncology, meaning that all ocular clinical studies and all ocular and nonocular animal, phantom, ex vivo, experimental, research and development, and purely methodological studies were excluded.

Results
Eleven articles met the inclusion criteria. The anatomic locations of the neoplasms in the selected articles were the gastrointestinal tract (2 articles), head and neck (1 article) and skin (8 articles).

Conclusions
While OCTA has shown great advancements in ophthalmology, its translation to the nonocular clinical oncology setting presents several limitations, with a lack of standardized protocols and interpretation guidelines posing the most significant challenge.

Imaging microvascular changes in nonocular oncological clinical applications by optical coherence tomography angiography: a literature review

Radiology and Oncology

This work is licensed under the Creative Commons Attribution 4.0 International License.

Background
Optical coherence tomography angiography (OCTA) is an emerging imaging modality that enables noninvasive visualization and analysis of tumor...

Imaging microvascular changes in nonocular oncological clinical applications by optical coherence tomography angiography: a literature review

Article Category: Review

Published Online: Nov 30, 2023

Page range: 411 - 418

Received: Sep 15, 2023

Accepted: Oct 03, 2023

DOI: https://doi.org/10.2478/raon-2023-0057

Keywords
optical coherence tomography angiography (OCTA), oncology, endoscopy, skin carcinoma

© 2023 Rok Hren et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Imaging microvascular changes in nonocular oncological clinical applications by optical coherence tomography angiography: a literature review

Article Category: Review

Published Online: Nov 30, 2023

Page range: 411 - 418

Received: Sep 15, 2023

Accepted: Oct 03, 2023

DOI: https://doi.org/10.2478/raon-2023-0057

Keywordsoptical coherence tomography angiography (OCTA), oncology, endoscopy, skin carcinoma

© 2023 Rok Hren et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
optical coherence tomography angiography (OCTA), oncology, endoscopy, skin carcinoma