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Figure 1

An example of an RT treatment plan (color wash display of isodoses with a minimal dose of 57 Gy, that is 95% of the prescribed dose of 60 Gy) in three planes. A RT plan for the same patient was prepared using a simultaneous integrated boost (left) and sequential boost (right). Target volumes are shown in blue contour (yellow labeled arrows). Dose assignment to the “PTV2-boost” target volume is the same in boost cases, 30 × 2.0 Gy. With sequential boost, overtreatment (red arrows) is observed in the area where a lower dose was prescribed.
An example of an RT treatment plan (color wash display of isodoses with a minimal dose of 57 Gy, that is 95% of the prescribed dose of 60 Gy) in three planes. A RT plan for the same patient was prepared using a simultaneous integrated boost (left) and sequential boost (right). Target volumes are shown in blue contour (yellow labeled arrows). Dose assignment to the “PTV2-boost” target volume is the same in boost cases, 30 × 2.0 Gy. With sequential boost, overtreatment (red arrows) is observed in the area where a lower dose was prescribed.

Recommendations for target definition according to EORTC, RTOG and ESTRO-ACROP

Contouring approach Dose prescription GTV CTV
EORTC single phase 30 × 2.0 Gy Resection cavity + residual T1 enhancement GTV + 2 cm
RTOG two phases 23 × 2.0 Gy GTV1: Resection cavity + residual T1 enhancement + FLAIR abnormality (oedema) CTV1 = GTV1 + 2 cm (the margin is 2.5 cm in cases where no oedema is presented)
+ 7 × 2.0 Gy GTV2: Resection cavity + residual T1 enhancement GTV2 + 2 cm
ESTRO-ACROP 30 × 2.0 Gy Resection cavity + residual T1 enhancement + FLAIR abnormality (oedema) for secondary glioblasomas GTV + 2 cm
eISSN:
1581-3207
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Medicine, Clinical Medicine, Radiology, Internal Medicine, Haematology, Oncology