<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>This retrospective single-centre study was conducted in an intensive care unit (ICU) in Pauls Stradiņš Clinical University Hospital (Rīga, Latvia) between 1 October 2020 and 30 April 2021. The aim was to assess the baseline clinical characteristics and their association with outcome for critically ill coronavirus disease 2019 (COVID-19) patients admitted to the ICU and requiring invasive mechanical ventilation (IMV). Demographic, clinical, laboratory, length-of-stay and mortality data were collected from medical records. In total, 66 critically ill patients admitted to the ICU were enrolled in this study. 77% were male, and the median age was 65.5 [57.0–70.8] years. Comorbidi-ties included obesity (67.2%), cardiovascular disease (63.6%) and type II diabetes (38.1%). Prone positioning was performed in most cases (68.2%) and one-third (34.8%) of patients required renal replacement therapy during their stay in the ICU. The median time to intubation after hospitalisation was eight [3.3–10.0] days. The median length-of-stay in the ICU was 12 [6.0–18.5] days and the overall mortality among all invasively ventilated patients in the ICU was 86%. In survivors, the duration of time between the onset of symptoms and hospitalisation, and time between the onset of symptoms and intubation, were found to be shorter than in non-survivors.</p>
</abstract>

This retrospective single-centre study was conducted in an intensive care unit (ICU) in Pauls Stradiņš Clinical University Hospital (Rīga, Latvia) between 1 October 2020 and 30 April 2021. The aim was to assess the baseline clinical characteristics and their association with outcome for critically ill coronavirus disease 2019 (COVID-19) patients admitted to the ICU and requiring invasive mechanical ventilation (IMV). Demographic, clinical, laboratory, length-of-stay and mortality data were collected from medical records. In total, 66 critically ill patients admitted to the ICU were enrolled in this study. 77% were male, and the median age was 65.5 [57.0–70.8] years. Comorbidi-ties included obesity (67.2%), cardiovascular disease (63.6%) and type II diabetes (38.1%). Prone positioning was performed in most cases (68.2%) and one-third (34.8%) of patients required renal replacement therapy during their stay in the ICU. The median time to intubation after hospitalisation was eight [3.3–10.0] days. The median length-of-stay in the ICU was 12 [6.0–18.5] days and the overall mortality among all invasively ventilated patients in the ICU was 86%. In survivors, the duration of time between the onset of symptoms and hospitalisation, and time between the onset of symptoms and intubation, were found to be shorter than in non-survivors.

Clinical Characteristics of Invasively Ventilated Covid-19 Patients: An Overview of Clinical Experience in Pauls Stradiņš Clinical University Hospital, Rīga, Latvia

Department of Anaesthesiology and Intensive Care

Pauls Stradiņš Clinical University Hospital

Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

This retrospective single-centre study was conducted in an intensive care unit (ICU) in Pauls Stradiņš Clinical University Hospital (Rīga, Latvia) between 1...

Clinical Characteristics of Invasively Ventilated Covid-19 Patients: An Overview of Clinical Experience in Pauls Stradiņš Clinical University Hospital, Rīga, Latvia

Published Online: Jul 23, 2022

Page range: 338 - 345

Received: Nov 15, 2021

Accepted: Jul 03, 2022

DOI: https://doi.org/10.2478/prolas-2022-0051

Keywords
SARS-CoV-2, invasive mechanical ventilation, intensive care unit, mortality

© 2022 Paula Zviedre et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Clinical Characteristics of Invasively Ventilated Covid-19 Patients: An Overview of Clinical Experience in Pauls Stradiņš Clinical University Hospital, Rīga, Latvia

Published Online: Jul 23, 2022

Page range: 338 - 345

Received: Nov 15, 2021

Accepted: Jul 03, 2022

DOI: https://doi.org/10.2478/prolas-2022-0051

KeywordsSARS-CoV-2, invasive mechanical ventilation, intensive care unit, mortality

© 2022 Paula Zviedre et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
SARS-CoV-2, invasive mechanical ventilation, intensive care unit, mortality