<abstract xmlns="http://www.w3.org/1999/xhtml">

In the available literature on this subject there are many studies which describe the effects of sexually transmitted infections on pregnancy and fertility of women. Because of the frequency of the infections with the atypical bacteria of the <italic>Ureaplasma</italic> Spp., <italic>Mycoplasma</italic> Spp., <italic>Chlamydia Trachomatis</italic>, as well as HPV infections in women of reproductive age, it is easy to underestimate their importance when establishing the basis of the genital health of women of reproductive age.
In this prospective analysis, conducted from 2014 to 2018 in the laboratory for HPV and Molecular diagnostics at the University Clinic of Gynaecology and Obstetrics in Skopje, North Macedonia, we analysed the results of 10,387 patients of all ages, of which 973 patients were of reproductive age. A Panel analysis was also conducted (including the above-mentioned pathogens). An HPV analysis was also conducted on 643 patients in this group. Within the group of 643 patients, there was a positive result for HPV in 26.7% of them, while in 40.9% there was a positive result for one or more pathogens on the Panel analysis of bacterial pathogens. The statistical analysis of the results showed that the most frequent of all bacterial pathogens within the Macedonian population of women of reproductive age is <italic>Ureaplasma</italic> Spp, with an incidence of 33%, followed by <italic>Mycoplasma</italic> Spp., with 7.8%, while <italic>Chlamydia Trachomatis</italic> was present in 6.4% of the cases. We should highlight that a co-infection with HPV was present in 18.5% of all the patients where there was analysis of both diagnostic procedures.
The analysis of the results in the patients co-infected with HPV and at least one bacterial pathogen on the Panel Analysis, showed a very high statistical correlation (p&lt;001).
</abstract>

In the available literature on this subject there are many studies which describe the effects of sexually transmitted infections on pregnancy and fertility of women. Because of the frequency of the infections with the atypical bacteria of the Ureaplasma Spp., Mycoplasma Spp., Chlamydia Trachomatis, as well as HPV infections in women of reproductive age, it is easy to underestimate their importance when establishing the basis of the genital health of women of reproductive age.
In this prospective analysis, conducted from 2014 to 2018 in the laboratory for HPV and Molecular diagnostics at the University Clinic of Gynaecology and Obstetrics in Skopje, North Macedonia, we analysed the results of 10,387 patients of all ages, of which 973 patients were of reproductive age. A Panel analysis was also conducted (including the above-mentioned pathogens). An HPV analysis was also conducted on 643 patients in this group. Within the group of 643 patients, there was a positive result for HPV in 26.7% of them, while in 40.9% there was a positive result for one or more pathogens on the Panel analysis of bacterial pathogens. The statistical analysis of the results showed that the most frequent of all bacterial pathogens within the Macedonian population of women of reproductive age is Ureaplasma Spp, with an incidence of 33%, followed by Mycoplasma Spp., with 7.8%, while Chlamydia Trachomatis was present in 6.4% of the cases. We should highlight that a co-infection with HPV was present in 18.5% of all the patients where there was analysis of both diagnostic procedures.
The analysis of the results in the patients co-infected with HPV and at least one bacterial pathogen on the Panel Analysis, showed a very high statistical correlation (p<001).

Incidence and Prevalence of Vaginal Infections in Women of Reproductive Age in North Macedonia

University Clinic of Gynecology and Obstetrics

PRILOZI

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

In the available literature on this subject there are many studies which describe the effects of sexually transmitted infections on pregnancy and fertility of...

Incidence and Prevalence of Vaginal Infections in Women of Reproductive Age in North Macedonia

Published Online: Jul 15, 2023

Page range: 73 - 80

DOI: https://doi.org/10.2478/prilozi-2023-0027

Keywords
vaginal infections, reproductive health, Spp., Spp., HPV, co-infections

© 2023 Jovana Albig et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Incidence and Prevalence of Vaginal Infections in Women of Reproductive Age in North Macedonia

Published Online: Jul 15, 2023

Page range: 73 - 80

DOI: https://doi.org/10.2478/prilozi-2023-0027

Keywordsvaginal infections, reproductive health, Spp., Spp., HPV, co-infections

© 2023 Jovana Albig et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
vaginal infections, reproductive health, Spp., Spp., HPV, co-infections