<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Renal transplantation is the most beneficial treatment in patients with chronic kidney disease (CKD), increasing life expectancy and improving quality of life. A better understanding of organ and tissue functions, the development of surgical techniques, and new and effective immunosuppressive and antimicrobial drugs increase the success of transplantation. However, the number of renal transplantations from living and cadaveric donors is not at the desired frequency. Among the leading causes of the restrictions for transplantation are both the recipients’ and donors’ chronic diseases. While hepatitis B and C infections are a significant problem affecting the number and success of renal transplantations, the innovation of hepatitis C virus treatments has improved outcomes. Thus, the recipient and donor hepatitis B and C virus infections are no longer considered as relative contraindications for renal transplantation. This review discusses the management of patients and donors with hepatitis B and hepatitis C in renal transplantation.</p>
</abstract>

Renal transplantation is the most beneficial treatment in patients with chronic kidney disease (CKD), increasing life expectancy and improving quality of life. A better understanding of organ and tissue functions, the development of surgical techniques, and new and effective immunosuppressive and antimicrobial drugs increase the success of transplantation. However, the number of renal transplantations from living and cadaveric donors is not at the desired frequency. Among the leading causes of the restrictions for transplantation are both the recipients’ and donors’ chronic diseases. While hepatitis B and C infections are a significant problem affecting the number and success of renal transplantations, the innovation of hepatitis C virus treatments has improved outcomes. Thus, the recipient and donor hepatitis B and C virus infections are no longer considered as relative contraindications for renal transplantation. This review discusses the management of patients and donors with hepatitis B and hepatitis C in renal transplantation.

Current Approach to Renal Transplantation Candidates and Potential Donors with Viral Hepatitis

Bahcesehir University Faculty of Medicine

Sutcu Imam University Faculty of Medicine

PRILOZI

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Renal transplantation is the most beneficial treatment in patients with chronic kidney disease (CKD), increasing life expectancy and improving quality of life....

Current Approach to Renal Transplantation Candidates and Potential Donors with Viral Hepatitis

Published Online: Mar 29, 2023

Page range: 135 - 144

DOI: https://doi.org/10.2478/prilozi-2023-0015

Keywords
Renal Transplantation, Hepatitis B Virus, Hepatitis C Virus, Direct-acting antiviral agents

© 2023 Berfu Korucu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Current Approach to Renal Transplantation Candidates and Potential Donors with Viral Hepatitis

Published Online: Mar 29, 2023

Page range: 135 - 144

DOI: https://doi.org/10.2478/prilozi-2023-0015

KeywordsRenal Transplantation, Hepatitis B Virus, Hepatitis C Virus, Direct-acting antiviral agents

© 2023 Berfu Korucu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Renal Transplantation, Hepatitis B Virus, Hepatitis C Virus, Direct-acting antiviral agents