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<p>Background: wild <italic>Coleus forskohlii L</italic>. is a well-known traditional medicine for the treatment of many diseases because of its high forskolin content and several diterpenes. Objective: this study aimed phytochemical screening, finding of total phenolic content (TPC), total flavonoid content (TFC) and antioxidation activity of <italic>Coleus forskohlii L</italic>. leavse extracts in Al-Leith area, Saudi Arabia. Materials and Methods: dry leaves of wild <italic>C. forskohlii L</italic>. were used. Four solvents from diverse polarity groups were tested on these leaves, which are ethanol, ethyl acetate, chloroform, and hexane. Moreover, obtained extracts were used in phytochemical analyzing, finding of total phenols, and antioxidation activity. Results: showed the presence of phenols, flavonoids, tannins, alkaloids, Proteins, carbohydrates, saponins, and glycosides in <italic>Coleus forskohlii L</italic>. leaves. The highest value of total phenolic content (TPC) was significantly (P &lt; 0.001) in ethanol extract (280.5±2.33 mg GAE/gm. Also, the highest value of total flavonoid content (TFC) was in ethanol extract (141.4±1.30 mg QE /g). The antioxidation activity was significantly (P &lt; 0.001) higher in ethanol extract (78.55±2.23%), followed by ethyl acetate extract (60.18±1.21%), chloroform extract (36.11±2.54%), and lowest value in hexane extract (20.71±0.59%). The study clearly indicated that the leaves extract of <italic>C. forskohlli L</italic>. collected from Al-Leith region- Saudi Arabia has properties to be useful in pharmacological and biological industries.</p>
</abstract>

Background: wild Coleus forskohlii L. is a well-known traditional medicine for the treatment of many diseases because of its high forskolin content and several diterpenes. Objective: this study aimed phytochemical screening, finding of total phenolic content (TPC), total flavonoid content (TFC) and antioxidation activity of Coleus forskohlii L. leavse extracts in Al-Leith area, Saudi Arabia. Materials and Methods: dry leaves of wild C. forskohlii L. were used. Four solvents from diverse polarity groups were tested on these leaves, which are ethanol, ethyl acetate, chloroform, and hexane. Moreover, obtained extracts were used in phytochemical analyzing, finding of total phenols, and antioxidation activity. Results: showed the presence of phenols, flavonoids, tannins, alkaloids, Proteins, carbohydrates, saponins, and glycosides in Coleus forskohlii L. leaves. The highest value of total phenolic content (TPC) was significantly (P < 0.001) in ethanol extract (280.5±2.33 mg GAE/gm. Also, the highest value of total flavonoid content (TFC) was in ethanol extract (141.4±1.30 mg QE /g). The antioxidation activity was significantly (P < 0.001) higher in ethanol extract (78.55±2.23%), followed by ethyl acetate extract (60.18±1.21%), chloroform extract (36.11±2.54%), and lowest value in hexane extract (20.71±0.59%). The study clearly indicated that the leaves extract of C. forskohlli L. collected from Al-Leith region- Saudi Arabia has properties to be useful in pharmacological and biological industries.

Phytochemical composition and antioxidant activity of leaves extracts of <italic>Coleus forskohlii L</italic>. collected from Al-Leith Area, Saudi Arabia

Chemistry Department, Faculty of Applied Sciences

Al-Leith University College, Umm Al-Qura University

Polish Journal of Chemical Technology

This work is licensed under the Creative Commons Attribution 4.0 International License.

Phytochemical composition and antioxidant activity of leaves extracts of . collected from Al-Leith Area, Saudi Arabia

Background: wild Coleus forskohlii L. is a well-known traditional medicine for the treatment of many diseases because of its high forskolin content and several...

Phytochemical composition and antioxidant activity of leaves extracts of Coleus forskohlii L. collected from Al-Leith Area, Saudi Arabia

Published Online: Oct 12, 2023

Page range: 56 - 62

DOI: https://doi.org/10.2478/pjct-2023-0025

Keywords
., Leaves Extracts, Phytochemical composition, Antioxidant activity

© 2023 Manal Y. Sameeh, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Phytochemical composition and antioxidant activity of leaves extracts of Coleus forskohlii L. collected from Al-Leith Area, Saudi Arabia

Published Online: Oct 12, 2023

Page range: 56 - 62

DOI: https://doi.org/10.2478/pjct-2023-0025

Keywords., Leaves Extracts, Phytochemical composition, Antioxidant activity

© 2023 Manal Y. Sameeh, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
., Leaves Extracts, Phytochemical composition, Antioxidant activity