<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Triptans are specific drugs for migraine attack, their use leads to selective vasoconstriction, while the inflammatory condition that usually occurs during migraine is reduced. The structurally indolamine derivatives are selective agonists of the serotonin 1B/1D receptor. This review presents the history, representatives, production, and physico-chemical properties of triptans, but also discusses their pharmacological properties and mechanism of action.</p></abstract>

Triptans are specific drugs for migraine attack, their use leads to selective vasoconstriction, while the inflammatory condition that usually occurs during migraine is reduced. The structurally indolamine derivatives are selective agonists of the serotonin 1B/1D receptor. This review presents the history, representatives, production, and physico-chemical properties of triptans, but also discusses their pharmacological properties and mechanism of action.

Chemical and pharmacological characterization of triptans

University of Medicine, Pharmacy, Science and Technology of Târgu Mureș

Bulletin of Medical Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Chemical and pharmacological characterization of triptans"}

Triptans are specific drugs for migraine attack, their use leads to selective vasoconstriction, while the inflammatory condition that usually occurs during...

Chemical and pharmacological characterization of triptans

Published Online: Feb 13, 2020

Page range: 53 - 60

Received: May 22, 2019

Accepted: Jul 01, 2019

DOI: https://doi.org/10.2478/orvtudert-2019-0007

Keywords
triptans, migraine, analytics, mechanism of action, pharmacokinetics

© 2019 Kelemen Hajnal et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Chemical and pharmacological characterization of triptans

Published Online: Feb 13, 2020

Page range: 53 - 60

Received: May 22, 2019

Accepted: Jul 01, 2019

DOI: https://doi.org/10.2478/orvtudert-2019-0007

Keywordstriptans, migraine, analytics, mechanism of action, pharmacokinetics

© 2019 Kelemen Hajnal et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
triptans, migraine, analytics, mechanism of action, pharmacokinetics