1. bookVolume 19 (2019): Issue 5 (October 2019)
Journal Details
License
Format
Journal
eISSN
1335-8871
First Published
07 Mar 2008
Publication timeframe
6 times per year
Languages
English
Open Access

Identification of Microrecording Artifacts with Wavelet Analysis and Convolutional Neural Network: An Image Recognition Approach

Published Online: 07 Oct 2019
Volume & Issue: Volume 19 (2019) - Issue 5 (October 2019)
Page range: 222 - 231
Received: 20 Mar 2019
Accepted: 30 Aug 2019
Journal Details
License
Format
Journal
eISSN
1335-8871
First Published
07 Mar 2008
Publication timeframe
6 times per year
Languages
English
Abstract

Deep brain stimulation (DBS) is an internationally accepted form of treatment option for selected patients with Parkinson’s disease and dystonia. Intraoperative extracellular microelectrode recordings (MER) are considered as the standard electrophysiological method for the precise positioning of the DBS electrode into the target brain structure. Pre-processing of MERs is a key phase in clinical analysis, with intraoperative microelectrode recordings being prone to several artifact groups (up to 25 %). The aim of this methodological article is to provide a convolutional neural network (CNN) processing pipeline for the detection of artifacts in an MER. We applied continuous wavelet transform (CWT) to generate an over-complete time–frequency representation. We demonstrated that when attempting to find artifacts in an MER, the new CNN + CWT provides a high level of accuracy (ACC = 88.1 %), identifies individual classes of artifacts (ACC = 75.3 %) and also offers artifact time onset detail, which can lead to a reduction in false positives/negatives. In summary, the presented methodology is capable of identifying and removing various artifacts in a comprehensive database of MER and represents a substantial improvement over the existing methodology. We believe that this approach will assist in the proposal of interesting clinical hypotheses and will have neurologically relevant effects.

Keywords

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