<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Skin chromophore phantoms are widely used for better understanding of the light interaction with tissue and for calibration of skin diagnostic imaging techniques. In this work, different phantoms were examined and compared in order to find biologically equivalent substances that are the most promising for this purpose. For mimicking the skin medium and layered structure, a fibrin matrix with epidermal and dermal cell inclusion was used. Synthesized bilirubin, red blood cells and nigrosin were taken as absorbers. For spectral analysis of the developed phantoms a computer-aided multispectral imaging system Nuance 2.4 (Cambridge Research &amp; Instrumentation, Inc., USA) was used. In this study, skin phantoms were created using such substances as bilirubin, melanin, haemoglobin and nigrosin</p></abstract>

Skin chromophore phantoms are widely used for better understanding of the light interaction with tissue and for calibration of skin diagnostic imaging techniques. In this work, different phantoms were examined and compared in order to find biologically equivalent substances that are the most promising for this purpose. For mimicking the skin medium and layered structure, a fibrin matrix with epidermal and dermal cell inclusion was used. Synthesized bilirubin, red blood cells and nigrosin were taken as absorbers. For spectral analysis of the developed phantoms a computer-aided multispectral imaging system Nuance 2.4 (Cambridge Research & Instrumentation, Inc., USA) was used. In this study, skin phantoms were created using such substances as bilirubin, melanin, haemoglobin and nigrosin

Development and Experimental Study of Phantoms for Mapping Skin Chromophores

Biophotonics Laboratory Institute of Atomic Physics and Spectroscopy, University of Latvia, 19 Raina Blvd., LV-1586, Riga, LATVIA

Latvian Journal of Physics and Technical Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Development and Experimental Study of Phantoms for Mapping Skin Chromophores"}

Skin chromophore phantoms are widely used for better understanding of the light interaction with tissue and for calibration of skin diagnostic imaging...

Development and Experimental Study of Phantoms for Mapping Skin Chromophores

Published Online: Jul 16, 2014

Page range: 58 - 66

DOI: https://doi.org/10.2478/lpts-2014-0020

© by A. Silapetere

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.