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Molecular detection and genetic diversity of porcine circovirus type 3 in commercial pig farms in Xinjiang province, China

Qiao Mengfan

Qiao Mengfan

  • College of Animal Science and Technology, Shihezi UniversityShihezi, China
  • School of Biotechnology, Central South UniversityChangsha, China
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Mengfan, Qiao
, 
Wang Xifeng

Wang Xifeng

College of Animal Science and Technology, Shihezi UniversityShihezi, China
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Xifeng, Wang
, 
Zhang Guowu

Zhang Guowu

College of Animal Science and Technology, Shihezi UniversityShihezi, China
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Guowu, Zhang
, 
Meng Qingling

Meng Qingling

College of Animal Science and Technology, Shihezi UniversityShihezi, China
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Qingling, Meng
, 
Qiao Jun

Qiao Jun

College of Animal Science and Technology, Shihezi UniversityShihezi, China
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Jun, Qiao
, 
Wang Lixia

Wang Lixia

College of Animal Science and Technology, Shihezi UniversityShihezi, China
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Lixia, Wang
, 
Cai Kuojun

Cai Kuojun

Center for Animal Disease Prevention and ControlUrumqi, China
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Kuojun, Cai
, 
Zhang Jinsheng

Zhang Jinsheng

Center for Animal Disease Prevention and ControlTacheng, China
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Jinsheng, Zhang
, 
Zhang Zaichao

Zhang Zaichao

Center for Animal Disease Prevention and ControlChangji, China
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Zaichao, Zhang
, 
Yu Weiwei

Yu Weiwei

Center for Animal Disease Prevention and ControlKorla, China
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Weiwei, Yu
, 
Peng Yelong

Peng Yelong

Center for Animal Disease Prevention and ControlAksu, China
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Yelong, Peng
 and 
Cai Xuepeng

Cai Xuepeng

State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural SciencesLanzhou, China
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Xuepeng, Cai
  
Dec 19, 2019
Molecular detection and genetic diversity of porcine circovirus type 3 in commercial pig farms in Xinjiang province, China's Cover Image
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Published Online: Dec 19, 2019
Page range: 481 - 488
Received: May 07, 2019
Accepted: Nov 22, 2019
DOI: https://doi.org/10.2478/jvetres-2019-0071
Keywords
© 2019 Q. Mengfan et al. published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Introduction

Porcine circovirus type 3 (PCV3) is a newly discovered porcine circovirus. The molecular characteristics and genetic evolution of PCV3 in Xinjiang province, China still being unclear, the aim of the study was their elucidation.

Material and Methods

A total of 393 clinical samples were collected from pigs on commercial farms in nine different regions of Xinjiang and phylogenetic analysis based on full-length Cap genes was performed.

Results

The prevalence at farm level was 100%, while in all the tested samples it was 22.39%. Nine PCV3 strains were detected in Xinjiang province and they shared 98.9–99.3% nucleotide and 97.5–100.0% Cap gene amino acid sequence identities with other epidemic strains from China and abroad. Compared with other epidemic strains of PCV3, there were 26 base mutation sites in the Cap gene in the nine Xinjiang strains, resulting in the mutation of amino acids at positions 20, 24, 75, 77, 108, 111 and 206. Phylogenetic analysis showed that these strains can be divided into two different genetic groups, to the first of which five strains affiliated and divided between subgroups 1.1 and 1.2, and to the second of which the other four strains affiliated and similarly divided between subgroups 2.1 and 2.2.

Conclusion

PCV3 circulates widely among commercial pig farms in Xinjiang province, China, and displays obvious genetic diversity. The results provide epidemiological information useful for the prevention and control of PCV3 infection in the pig industry.

Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Life Sciences, Molecular Biology, Microbiology and Virology, Life Sciences, other, Medicine, Veterinary Medicine
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