<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Cardiovascular disorders have been described as relevant risk factor for severe COVID infection. Stent thrombosis is a life-threatening complication that may occur subacutely. We present an interesting case of a middle-aged woman who developed acute stent thrombosis while interrupting dual antiplatelet therapy (DAPT) ticagrelor, during an episode of coronavirus disease (COVID-19). In our case, the patient’s not-compliance to DAPT, associated with COVID-19 infection and a hyperinflammatory and hypercoagulable state associated with it played a major role in the development of stent thrombosis. The hypercoagulable and hyperinflammatory state associated with COVID-19 has important implications for cardiac patients, especially those undergoing complex coronary intervention, predisposing them to an increased risk of post-PCI complications.</p>
</abstract>

Cardiovascular disorders have been described as relevant risk factor for severe COVID infection. Stent thrombosis is a life-threatening complication that may occur subacutely. We present an interesting case of a middle-aged woman who developed acute stent thrombosis while interrupting dual antiplatelet therapy (DAPT) ticagrelor, during an episode of coronavirus disease (COVID-19). In our case, the patient’s not-compliance to DAPT, associated with COVID-19 infection and a hyperinflammatory and hypercoagulable state associated with it played a major role in the development of stent thrombosis. The hypercoagulable and hyperinflammatory state associated with COVID-19 has important implications for cardiac patients, especially those undergoing complex coronary intervention, predisposing them to an increased risk of post-PCI complications.

Double Trouble: Interrupting DAPT and COVID-19

“George Emil Palade” University of Medicine, Pharmacy, Science and Technology

Journal of Cardiovascular Emergencies

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Double Trouble: Interrupting DAPT and COVID-19"}

Cardiovascular disorders have been described as relevant risk factor for severe COVID infection. Stent thrombosis is a life-threatening complication that may...

Double Trouble: Interrupting DAPT and COVID-19

Published Online: Oct 14, 2022

Page range: 39 - 42

Received: Jul 13, 2022

Accepted: Aug 15, 2022

DOI: https://doi.org/10.2478/jce-2022-0007

Keywords
COVID-19, stent thrombosis, dual antiplatelet therapy, hypercoagulability

© 2022 Theofana Mihăilă et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Double Trouble: Interrupting DAPT and COVID-19

Published Online: Oct 14, 2022

Page range: 39 - 42

Received: Jul 13, 2022

Accepted: Aug 15, 2022

DOI: https://doi.org/10.2478/jce-2022-0007

KeywordsCOVID-19, stent thrombosis, dual antiplatelet therapy, hypercoagulability

© 2022 Theofana Mihăilă et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
COVID-19, stent thrombosis, dual antiplatelet therapy, hypercoagulability