1. bookVolume 12 (2019): Issue 2 (October 2019)
Journal Details
First Published
19 Jun 2009
Publication timeframe
4 times per year
Open Access

Aluminium toxicosis: a review of toxic actions and effects

Published Online: 20 Feb 2020
Volume & Issue: Volume 12 (2019) - Issue 2 (October 2019)
Page range: 45 - 70
Received: 22 Nov 2018
Accepted: 29 Aug 2019
Journal Details
First Published
19 Jun 2009
Publication timeframe
4 times per year

Abd-Elhady RM, Elsheikh AM, Khalifa AE. (2013). Anti-amnestic properties of Ginkgo biloba extract on impaired memory function induced by aluminum in rats. Int J Dev Neurosci31(7): 398–607.Search in Google Scholar

Abdel-Wahab WM. (2012). AlCl3-induced toxicity and oxidative stress in liver of male rats: protection by melatonin. Life Sci J9: 1173–1182.Search in Google Scholar

Abder-Rahman H. (1999). Effect of aluminum phosphide on blood glucose level. Vet Hum Toxicol41: 31–32.Search in Google Scholar

Abedini M, Fatehi F, Tabrizi N. (2014). Ischemic stroke as a rare manifestation of aluminium phosphide poisoning: a case report. Acta Med Iran52(12): 947–949.Search in Google Scholar

Abraham TM, Fox CS. (2013). Implications of rising prediabetes prevalence. Diabetes Care36(8): 2139–2141.Search in Google Scholar

Abubakar MG, Taylor A, Ferns GA. (2004). The effects of aluminium and selenium supplementation on brain and liver antioxidant status in the rat. Afr J Biotechnol 3: 88–93.Search in Google Scholar

Adzersen KH, Becker N, Steindorf K,Frentzel-Beyme R. (2003). Cancer mortality in a cohort of male German iron foundry workers. Am J Ind Med43: 295–305.Search in Google Scholar

Afridi HI, Kazi TG, Kazi N, Baig JA, Jamali MK, Arain MB, Sarfraz RA, Sheikh HU, Kandhro GA, Shah AQ. (2009). Status of essential trace metals in biological samples of diabetic mother and their neonates. Arch Gynecol Obstet280: 415–423.Search in Google Scholar

Afridi HI, Talpur FN, Kazi TG, Brabazon D. (2015). Effect of trace and toxic elements of different brands of cigarettes on the essential elemental status of Irish referent and diabetic mellitus consumers. Trace Elem Res167(2): 209–224.Search in Google Scholar

Aguilar MV, Saavedra P, Arrieta FJ, Mateos CJ, Gonzalez MJ, Meseguer I, Martinez-Para MC. (2007). Plasma mineral content in type-2 diabetic patients and their association with the metabolic syndrome. Ann Nutr Metab51: 402–406.Search in Google Scholar

Ahmad W. (2013). Overlapped metabolic and therapeutic links between Alzheimer’s disease and diabetes. Mol Neurobiol47(1): 399–424.Search in Google Scholar

Ahn HW, Fulton B, Moxon D, Jeffery EH. (1995). Interactive effects of fluoride and aluminum uptake and accumulation in bones of rabbits administered both agents in their drinking water. J Toxicol Environ Health44: 337–350.Search in Google Scholar

Akhlaghi F, Bagheri SM, Rajabi O. (2012). A comparative study of relationship between micronutrients and gestational diabetes. ISRN Obstet Gynecol2012, Article ID 470419, 4 pages, http://dx.doi.org/10.5402/2012/470419.10.5402/2012/470419344088022988520Search in Google Scholar

Akinola OB, Biliaminu SA, Adedeji OG, Oluwaseun BS, Olawoyin OM, Adelabu TA. (2016). Combined effects of chronic hyperglycaemia and oral aluminium intoxication on testicular tissue and some male reproductive paameters in Wistar rats. Andrologia48(7): 779–786.Search in Google Scholar

Al-Qayim MAJ, Ghali LS, Al-Azwai TS. (2014). Comparative effects of propolis and malic acid on hematological parameters of aluminum exposed male rats. Global J Bio-Sci Biotechnol3: 6–11.Search in Google Scholar

Alfrey AC. (1980). Aluminum metabolism in uremia. Neurotoxicology1: 43–53.Search in Google Scholar

Alfrey AC. (1993). Aluminum toxicity in patients with chronic renal failure. Ther Drug Monit15(6): 593–597.Search in Google Scholar

Alfrey AC, Solomons C. (1976). Bone pyrophosphate in uremia and its association with extraosseous calcification. J Clin Invest57: 700–705.Search in Google Scholar

Alter P, Grimm W, Maisch B. (2001). Lethal heart failure caused by aluminium phosphide poisoning. Intensive Care Med27: 327–331.Search in Google Scholar

Anane R, Creppy EE. (2001). Lipid peroxidation as pathway of aluminium cytotoxicity in human skin fibroblast cultures: prevention by superoxide dismutase+catalase and vitamins E and C. Hum Exp Toxicol20: 477–481.Search in Google Scholar

Andreoli SP. (1990). Aluminum levels in children with chronic renal failure who consume low phosphorus infant formula. J Pediatr116: 282–285.Search in Google Scholar

Anon (1982). Drinking Water and Health. National Research Council, National Academy Press, Washington, DC 4: 155–201.Search in Google Scholar

Anon (2008a). Aluminum and compounds. Hazardous Substances Data Bank. Bethesda, MD: National Library of Medicine. http://toxnet.nlm.nih.gov/cgibin/sis/htmlgen?HSDB Accessed 9 January 2016.Search in Google Scholar

Anon (2008b). Safety of aluminium from dietary intake. EFSA J754: 1–34.Search in Google Scholar

Anon (2008c). Toxicological profile for aluminum. Atlanta, GA, United States Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry. http://www.atsdr.cdc.gov/tox-profiles/tp22.pdf Accessed 27 January 2016.Search in Google Scholar

Anon (2011). On the evaluation of a new study to the bioavailability of aluminium in food. EFSA J9: 1–16.Search in Google Scholar

Arain MS, Afridi HI, Kazi TG, Talpur FN, Arain MB, Kazi A, Arain SA, Ali J. (2015). Correlation of aluminum and manganese concentrations in scalp hair samples of patients having neurological disorders. Environ Monit Assess187(2): 10.Search in Google Scholar

Arnold SE, Arvanitakis Z, Macauley-Rambach SL, Koenig AM, Wang H, Ahima RS, Craft S, Gandy S, Buettner C, Stoeckel LE, Holtzman DM, Nathan DM. (2018). Brain insulin resistance in type 2 diabetes and Alzheimer’s disease: concept and conumdrums. Nature Rev Neurol14(3): 168–181.Search in Google Scholar

Bacon R, Tavill A, Brittenham G, Park C, Recknagel R. (1983). Hepatic lipid peroxidation in vivo in rats with chronic iron overload. J Clin Invest71: 429–439.Search in Google Scholar

Bai C, Wang F, Zhao H, Li Y. (2012). Effects of subchronic aluminum exposure on liver function in rats. J Northeast Agric Univ19(2): 62–65.Search in Google Scholar

Bakir A, Darbre PD. (2015). Effect of aluminium on migration of oestrogen unresponsive MDA-MB-231 human breast cancer cells in culture. J Inorg Biochem152: 180–185.Search in Google Scholar

Bank WA, Kastin AJ, Maness LM, Huang W, Jaspan JB. (1995). Permeability of the blood-brain barrier by amylin. Life Sci57(22): 1993–2001.Search in Google Scholar

Bataineh H, Al-Hamood MH, Elbetieha AM. (1998). Assessment of aggressive, sexual behavior and fertility in adult rat following long term ingestion of four industrial metals salts. Hum Exp Toxicol17: 570–579.Search in Google Scholar

Bazzari F, Abdallah DM, El-Abhar HS. (2019). Chenodeoxycholic acid ameliorates AlCl3-induced Alzheimer’s disease neurotoxicity and cognitive deterioration via enhanced insulin signaling in rats. Molecules24(10): 1992.Search in Google Scholar

Bazzoni GB, Bollini AN, Hernández GN, Contini MC, Rasia ML (2005). In vivo effect of aluminium upon the physical properties of the erythrocyte membrane. J Inorg Biochem99(3): 822–827.Search in Google Scholar

Becaria A, Campbell A, Bondy SC. (2002). Aluminum as a toxicant. Toxicol Ind Health10(7): 309–320.Search in Google Scholar

Belaïd-Nouira Y, Bakhta H, Haouas Z, Flehi-Slim I, Cheikh HB. (2013). Fenu-greek seeds reduce aluminum toxicity associated with renal failure in rats. Nutr Res Pract7: 466–474.Search in Google Scholar

Biego GH, Joyeux M, Hartemann P, Debry G. (1998). Daily intake of essential minerals and metallic micropollutants from foods in France. Sci Total Environ217: 27–36.Search in Google Scholar

Bilkei-Gorzó A. (1993). Neurotoxic effect of enteral aluminum. Food Chem Toxicol31: 357–361.Search in Google Scholar

Bitra VR, Rapaka D, Mathala N, Akula A. (2014). Effect of wheat grass powder on aluminum induced Alzheimer’s disease in Wister rats. Asian Pac J Trop Med7(S1): S278–S281.Search in Google Scholar

Blaylock RL. (2012). Aluminium induced immunoexcitotoxicity in neurodevelopmental and neurodegenerative disorders. Current Inorg Chem2: 1–8.Search in Google Scholar

Bogdanović M, Janeva AB, Bulat P. (2008). Histopathological changes in rat liver after a single high dose of aluminium. Arch Ind Hyg Toxicol59: 97–101.Search in Google Scholar

Bondy SC. (2016). Low levels of aluminum can lead to behavioral and morphological changes associated with Alzheimer’s disease and age-related neurodegeneration. Neurotoxicology52: 222–229.Search in Google Scholar

Bondy SC, Truong A. (1999). Potentiation of beta-folding of β-amyloid peptide 25-35 by aluminum salts. Neurosci Lett267(1): 25–28.Search in Google Scholar

Boran AM, Al-Khatib AJ, Alanazi BS, Massadeh AM (2013). Investigation of aluminum toxicity among workers in aluminum industry sector. Eur Scient J9: 440–451.Search in Google Scholar

Boyce BF, Mocan MZ, Junor BJR. (1986). Toxic effect of aluminium and other substances on bone turnover. Nefrologia6: 103–108.Search in Google Scholar

Brown S, Savory J, Wills MR. (1987). Absorption of aluminum from citrate or chloride in everted rat gut sac. Clin Chem33: 933–934.Search in Google Scholar

Browne BA, McColl JG, Driscoll CT. (1990). Aluminum speciation using morin: I. morin and its complexes with aluminum. J Environ Qual19: 65–82.Search in Google Scholar

Buraimoh AA, Ojo SA. (2012). Effects of aluminium chloride exposure on the histology of the small intestine of wistar rats. Int J Appl Sci Technol2(10): 123–132.Search in Google Scholar

Buraimoh AA, Ojo SA. (2013). Effects of aluminium chloride exposure on the histology of lungs of wistar rats. J Appl Pharm Sci3: 108–112.Search in Google Scholar

Burge PS, Scott JA, McCoach J. (2000). Occupational asthma caused by aluminum. Allergy55(8): 77–780.Search in Google Scholar

Burgoin BP. (1992). Alumino-silicate content in calcium supplements derived from various carbonate deposits. Bull Environ Contam Toxicol48: 803–808.Search in Google Scholar

Bushinsky DA, Sprague SM, Hallegot P, Girod C, Chabala JM, Levi-Setti R. (1995). Effect of aluminum on bone surface ion composition. J Bone Miner Res10: 1988–1997.Search in Google Scholar

Cao Z, Fu Y, Sun X, Zhang Q, Xu F, Li Y. (2016). Aluminum inhibits osteoblastic differentiation through inactivation of Wnt/β-catenin signaling pathway in rat osteoblasts. Environ Toxicol Pharmacol42: 198–204.Search in Google Scholar

Campbell A, Bondy SC. (2000). Aluminum induced oxidative events and its relation to inflammation: a role for the metal in Alzheimer’s disease. Cell Mol Biol46(4): 721–730.Search in Google Scholar

Campbell A, Prasad KN, Bondy SC. (1999). Aluminum-induced oxidative events in cell lines: glioma are more responsive than neuroblastoma. Free Rad Biol Med26: 1166–1671.Search in Google Scholar

Campbell PGC, Hansen HJ, Dubreuil B, Nelson WO. (1992). Geochemistry of Quebec north shore salmon rivers during snowmelt: Organic acid pulse and aluminum mobilization. Can J Fish Aquat Sci49: 1938–1952.Search in Google Scholar

Cannata JB, Briggs JD, Junor BJ, Fell GS, Beastall G. (1983). Effect of acute aluminium overload on calcium and parathyroid-hormone metabolism. Lancet1(8323): 501–503.Search in Google Scholar

Capdevielle MC, Scanes CG. (1995). Effect of dietary acid or aluminum on growth and growth-related hormones in mallard ducklings (Anas platyrhynchos). Arch Environ Contam Toxicol29(4): 462–468.Search in Google Scholar

Cech I, Montera J. (2000). Spatial variations in total aluminum concentrations in drinking water supplies studied by geographic information system (GIS) methods. Water Res34: 2703–2712.Search in Google Scholar

Chafe R, Aslanov R, Sarkar A, Gregory P, Comeau A, Newhook LA. (2018). Association of type 1 diabetes and concentrations of drinking water components in Newfoundland and Labrador, Canada. BMJ Open Diabetes Res Care 6(1): e000466.Search in Google Scholar

Chappard D, Bizot P, Mabilleau G, Hubert L. (2016). Aluminum and bone: review of new clinical circumstances associated with Al(3+) deposition in the calcified matrix of bone. Morphologie100(329): 95–105.Search in Google Scholar

Chen BB, Zeng Y, Hu B. (2010). Study on speciation of aluminum in human serum using zwitterionic bile acid derivative dynamically coated C18 column HPLC separation with UV and on-line ICP-MS detection. Talanta81: 180–186.Search in Google Scholar

Chen WJ, Monnat RJ Jr, Chen M, Mottet NK. (1978). Aluminum induced pulmonary granulomatosis. Hum Pathol9(6): 705–711.Search in Google Scholar

Chen YW, Yang CY, Huang CF, Hung DZ, Leung YM, Liu SH. (2009). Heavy metals, islet function and diabetes development. Islets1: 169–176.Search in Google Scholar

Chen Z, Zhong C. (2014). Oxidative stress in Alzheimer’s disease. Neurosci Bull30(2): 271–281.Search in Google Scholar

Cheng D, Tang J, Wang X, Zhang X, Wang S. (2018). Effect of aluminum (Al) speciation on erythrocytic antioxidant defense process: Correlations between lipid membrane peroxidation and morphological characteristics. Ecotoxicol Environ Saf157: 201–206.Search in Google Scholar

Cheng D, Zhang X, Tang J, Kong Y, Wang X, Wang S. (2019). Chlorogenic acid protects against aluminum toxicity via MAPK/Akt signaling pathway in murine RAW264.7 macrophages. J Inorg Biochem190: 113–120.Search in Google Scholar

Cheng D, Zhang X, Xu L, Li X, Hou L, Wang C. (2017). Protective and prophylactic effects of chlorogenic acid on aluminum-induced acute hepatotoxicity in mice. Chem Biol Interact273: 125–132.Search in Google Scholar

Chines A, Pacifici R. (1990). Antacid and sucralfate-induced hypophosphatemic osteomalacia: A case report and review of the literature. Calcif Tissue Int47: 291–295.Search in Google Scholar

Chinoy NJ, Patel TN. (2001). Effect of sodium fluoride and aluminium chloride on ovary and uterus of mice and their reversal by some antidotes. Fluoride34(1): 9–20.Search in Google Scholar

Chmielnicka J, Nasiadek M, Pinkowski R, Paradowski M. (1994). Disturbances of morphological parameters in blood of rats orally exposed to aluminum chloride. Biol Trace Elem Res42: 191–199.Search in Google Scholar

Chopra JS, Kalra OP, Malik VS, Sharma R, Chandna A. (1986). Aluminum phosphide poisoning: A prospective study of 16 cases in one year. Postgrad Med J62: 1113–1115.Search in Google Scholar

Christie H, MacKay RJ, Fisher AM. (1963). Pulmonary effects of inhalation of aluminum by rats and hamsters. AIHA J (Fairfax, Va)24: 47–56.Search in Google Scholar

Codling EE, Chaney RL,Mulchi CL. (2002). Biomass yield and phosphorus availability to wheat grown on high phosphorus soils amended with phosphate inactivating residues. I. Drinking water treatment residue. Commun Soil Sci Plant Anal33: 1039–1061.Search in Google Scholar

Colomina MT, Peris-Sampedro F. (2017). Aluminum and Alzheimer’s disease. Adv Neurobiol18: 183–197.Search in Google Scholar

Colomina MT, Roig JL, Sanchez DJ, Domingo JL. (2002). Influence of age on aluminum-induced neurobehavioral effects and morphological changes in rat brain. Neurotoxicology23: 775–781.Search in Google Scholar

Contini MC, Ferri A, Bernal CA, Carnovale CE. (2007). Study of iron homeostasis following partial hepatectomy in rats with chronic aluminum intoxication. Biol Trace Elem Res115: 31–45.Search in Google Scholar

Cournot-Witmer G, Plachot JJ. (1990). Parathyroid glands in chronic aluminum intoxication. Ultrastruct Pathol14(3): 211–219.Search in Google Scholar

Cox KA, Dunn MA. (2001). Aluminum toxicity alters the regulation of calbindin-D28k protein and mRNA expression in chick intestine. J Nutr131(7): 2007–2013.Search in Google Scholar

Crisponi G, Nurchi VM, Bertolasi V, Remelli M, Faa G. (2012). Chelating agents for human diseases related to aluminium overload. Coord Chem Rev256: 89–104.Search in Google Scholar

Cronan CS, Schofield CL. (1979). Aluminum leeching response to acid precipitation: Effect on high-elevation watersheds in the northeast. Science204: 304–306.Search in Google Scholar

Darbre PD. (2016). Aluminium and the human breast. Morphologie100(329): 65–74.Search in Google Scholar

Darbre PD, Bakir A, Iskakova E. (2013a). Effect of aluminium on migratory and invasive properties of MCF-7 human breast cancer cells in culture. J Inorg Biochem128: 245–249.10.1016/j.jinorgbio.2013.07.00423896199Search in Google Scholar

Darbre PD, Mannello F, Exley C. (2013b). Aluminium and breast cancer: sources of exposure, tissue measurmenets and mechanisms of toxicological actions of breast of breast biology. J Inorg Biochem128: 257–261.10.1016/j.jinorgbio.2013.07.00523899626Search in Google Scholar

Darbre PD, Pugazhendhi D, Mannello F. (2011). Aluminium and Human breast diseases. J Inorg Biochem105(11): 1484–1488.Search in Google Scholar

Dasappa H, Fathima FN, Prabhkar R, Sarin S. (2015). Prevalence of diabetes and prediabetes and assessment of risk factors in urban slums of Bangalore. J Family Med Prim Care4(3): 399–404.Search in Google Scholar

Day JP. (1986). Chemical aspects of aluminum chelation by desferrioxamine, in Aluminum and other trace elements in renal disease (Taylor A ed) pp. 184–192, Baillere-Tindall, London.Search in Google Scholar

Day JP, Barker J, Evans LJA, Perks J, Seabright PJ, Ackrill P, Lilley JS, Drumm PV, Newton GWA. (1991). Aluminum absorption studied by 26Al tracer. Lancet337: 1345.Search in Google Scholar

de Chambrun GP, Body-Malapel M, Frey-Wagner I, Djouina M, Deknuydt F, Atrott K, Esquerre N, Altare F, Neut C, Arrieta MC, Kanneganti T-D, Rogler G, Colombel JF, Cortot A, Desreumaux P, Vignal C. (2014). Aluminum enhances inflammation and decreases mucosal healing in experimental colitis in mice. Mucosal Immunol7(3): 589–601.Search in Google Scholar

de la Monte SM, Wand JR. (2008). Alzheimer’s disease is type 3 diabetes-Evidence reviewed. J Diabetes Sci Technol2(6): 1101–1113.Search in Google Scholar

Delhaize E, Ryan RP. (1995). Aluminum toxicity and tolerance in plants. Plant Physiol107: 315–321.Search in Google Scholar

Deugnier JL. (2003). Iron and liver cancer. Alcohol30: 145–150.Search in Google Scholar

DeVoto E, Yokel RA. (1994). The biological speciation and toxicokinetics of aluminum. Environ Health Perspect102: 940–951.Search in Google Scholar

de Vuyst P, Dumortier P, Schandené L, Estenne M, Verhest A, Yernault JC. (1987). Sarcoid-like lung granulomatosis induced by aluminum dusts. Am Rev Respir Dis135(2): 493–497.Search in Google Scholar

Díaz-Corte C, Fernández-Martín JL, Barreto S, Gómez C, Fernández-Coto T, Braga S, Cannata JB. (2001). Effect of aluminium load on parathyroid hormone synthesis. Nephrol Dial Transplant16(4): 742–745.Search in Google Scholar

Dixon RL, Sherins RJ, Lee IP. (1979). Assessment of environmental factors affecting male fertility. Environ Health Perspect30: 53–68.Search in Google Scholar

Dokken BB, Saengsirisuwan V, Kim JS, Teachey MK, Henriksen EJ. (2008). Oxidative stress-induced insulin resistance in rat skeletal muscle: role of glycogen synthase kinase-3. American Jounal of Physiology. Endocrinol Metab294(3): E615–621.Search in Google Scholar

Domingo JL. (1995). Reproductive and developmental toxicity of aluminum: a review. Neurotoxicology17(4): 515–521.Search in Google Scholar

Domingo JL, Gomez M, Liobet JM, Corbella J. (1988). Comparative effects of several chelating agents on the toxicity, distribution, and excretion of aluminum. Hum Toxicol7: 259–262.Search in Google Scholar

Domingo JL, Llobet JM, Gomez M, Tomas JM, Corbella J. (1987). Nutritional and toxicological effects of short-term ingestion of aluminum by the rat. Res Commun Chem Pathol Pharmacol56: 409–419.Search in Google Scholar

D’Souza SP, Vijayalaxmi KK, Prashantha N. (2014). Assessment of genotoxicity of aluminium acetate in bone marrow, male germ cells and fetal cells of Swiss albino mice. Mutat Res Genet Toxicol Environ Mutagen766: 16–22.Search in Google Scholar

Drüeke T, Touam M, Lacour B. (1986). Aluminum-induced microcytic anemia in experimental chronic renal failure. Nefrologia6: 67–69.Search in Google Scholar

Dunn MA, Ishizakie AS, Liew MYB, Too SL, Johnson N. (1995). Dietary aluminum chloride inhibits the ability of vitamin D to regulate intestinal calbindin-D28k levels in chicks. J Trace Elem Exp Med8: 47–57.Search in Google Scholar

Edwardson JA, Moore PB, Ferrier IN, Lilley JS, Newton GWA, Barker J, Templar J, Day JP. (1993). Effect of silicon on gastrointestinal absorption of aluminium. Lancet342: 211–212.Search in Google Scholar

Eisenreich SJ. (1980). Atmospheric input of trace metals to Lake Michigan (USA). Water Air Soil Pollut13: 287–301.Search in Google Scholar

El Mazoudy RH, Bekhet GA. (2016). In ovo toxico-teratological effects of aluminum on embryonic chick heart and vascularization. Environ Sci Pollut Res Int23(21): 21947–21956.Search in Google Scholar

Exley C. (2004). The proxidant activity of aluminium. Free Rad Biol Med36(3): 380–387.Search in Google Scholar

Exley C. (2006). Aluminium and iron, but neither copper nor zinc, are key to the precipitation of beta-sheets of A beta (42) in senile plaque cores in Alzheimer’s disease. J Alzheimers Dis 10: 173–177.Search in Google Scholar

Exley C. (2013). Human exposure to aluminium. Environ Sci Process Impacts15: 1807–1816.Search in Google Scholar

Exley C. (2016). The toxicity of aluminium in humans. Morphologie100(329): 51–55.Search in Google Scholar

Exley C, Begum A, Woolley MP, Bloor RN. (2006). Aluminum in tobacco and cannabis and smoking-related disease. Am J Med119(3): 276.e9–11.Search in Google Scholar

Exley C, Birchall JD. (1992). The cellular toxicity of aliminium. J Theor Biol159(1): 83–98.Search in Google Scholar

Exley C, Birchall JD, Price N. (1994). Luminum inhibition of hexokinase activity in vitro: A study in biological availability. J Inorg Biochem54(4): 297–304.Search in Google Scholar

Exley C, House E. (2011). Aluminium in the human brain. Monatshefte fur Chemie 142: 357–363.Search in Google Scholar

Exley C, Price NC, Kelly SM, Birchall JD. (1993). An interaction of β-amyloid with aluminium in vitro. FEBS Lett324(3): 293–295.Search in Google Scholar

Exley C, Siesjo P, Eriksson H. (2010). The immunobiology of aluminium adjuvants: how do they really work? Trends Immunol31: 103–109.10.1016/j.it.2009.12.00920153253Search in Google Scholar

Exley C, Swarbrick L, Gherardi RK, Authier FJ. (2009). A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome. Med Hypotheses72(2): 135–139.Search in Google Scholar

Fanti P, Kindy MS, Mohapatra S, Klein J, Columbo G, Malluche HH. (1992). Dose-dependent effects of aluminum on osteocalcin synthesis in osteo-blast like ROS 17/2 cells in culture. Am J Physiol263: E1113–E1118.Search in Google Scholar

Farina M, Rotta LN, Soares FA, Jardim F, Jacques R, Souza DO, Rocha JB. (2005). Hematological changes in rats chronically exposed to oral aluminum. Toxicology209: 29–37.Search in Google Scholar

Fernández MS. (2014). Human IAPP amyloidogenic properties and pancreatic β-cell death. Cell Calcium56(5): 416–427.Search in Google Scholar

Feinroth M, Feinroth MV, Berlyne GM. (1984). Aluminum absorption in the rat everted gut sac. Miner Electrolyte Metab8: 29–35.Search in Google Scholar

Feng W, Cui X, Liu B, Liu C, Xiao Y, Lu W, Guo H, He M, Zhang X, Yuan J, Chen W,Wu T. (2015). Association of urinary metal profiles with altered glucose levels and diabetes risk: a population-based study in China. PLoS One10: 1–11.Search in Google Scholar

Filipek LH, Nordstrom DK, Ficklin WH. (1987). Interaction of acid mine drainage with waters and sediments of West Squaw Creek in the West Shasta mining district, California. Environ Sci Technol21: 388–396.Search in Google Scholar

Flaten TP. (2001). Aluminium as a risk factor in Alzheimer’s disease, with emphasis on drinking water. Brain Res Bull55(2): 187–196.Search in Google Scholar

Flaten TP. (2002). Aluminium in tea-concentrations, speciation and bioavail-ability. Coord Chem Rev228: 385–395.Search in Google Scholar

Florence AL, Gauthier A, Ponsar C, Van den Bosch de Aguilar P, Crichton RR. (1994). An experimental animal model of aluminum overload. Neurodegeneration3: 315–323.Search in Google Scholar

Flores CR, Puga MP, Wrobel K, Sevilla MEG, Wrobel K. (2011). Trace elements status in diabetes mellitus type 2: Possible role of the interaction between molybdenum and copper in the progress of typical complications. Diabetes Res Clin Pract91: 333–341.Search in Google Scholar

Fogarty U, Perl D, Good P, Ensley S, Seawright A, Noonan J. (1998). A cluster of equine granulomatous enteritis cases: the link with aluminium. Vet Hum Toxicol40(5): 297–305.Search in Google Scholar

Fu Y, Jia FB, Wang J, Song M, Liu SM, Li YF, Liu SZ, Bu QW. (2014). Effects of sub-chronic aluminum chloride exposure on rat ovaries. Life Sci100(1): 61–66.Search in Google Scholar

Fyiad AA. (2007). Aluminium toxicity and oxidative damage reduction by melatonin in rats. J Appl Sci Res3: 1210–1217.Search in Google Scholar

Ganrot PO. (1986). Metabolism and possible health effects of aluminum. Environ Health Perspect65: 363–441.Search in Google Scholar

Garbossa G, Galvez G, Castro ME, Nesse A. (1998). Oral aluminum administration to rats with normal renal function. 1. Impairment of erythropoiesis. Hum Exp Toxicol17: 312–317.Search in Google Scholar

Garbossa G, Gutnisky A, Nesse A. (1996). Depressed erythroid progenitor cell activity in aluminum overloaded mice. Miner Electrolyte Metab22: 214–218.Search in Google Scholar

Garruto RM, Shankar SK, Yanagihara R, Salazar AM, Amyx HL, Gajdusek DC. (1989). Low-calcium, high-aluminum diet-induced motor neuron pathology in cynomolgus monkeys. Acta Neuropathol78: 210–219.Search in Google Scholar

Gensemer RW, Playle RC. (1999). The bioavailability and toxicity of aluminum in aquatic environments. Crit Rev Environ Sci Technol29(4): 315–450.Search in Google Scholar

Gherardi RK, Aouizerate J, Cadusseau J, Yara S, Authier FJ. (2016). Aluminum adjuvants of vaccines injected in muscle: Normal fate, pathology and associated disease. Morphologie100(329): 85–94.Search in Google Scholar

Gherardi RK, Authier FJ. (2012). Macrophagic myofaciitis: characterization and pathophysiology. Lupus21(2): 184–189.Search in Google Scholar

Glanz JM, Newcomer SR, Daley MF, McClure DL, Baxter RP, Jackson ML, Naleway AL, Lugg MM, DeStefano F. (2015). Cummulative and episodic vaccine aluminum exposure in a population based cohort of young children. Vaccine33(48): 6736–6744.Search in Google Scholar

Golub MS, Germann SI. (2001). Long-term consequences of developmental exposure to aluminum in a suboptimal diet for growth and behavior of Swiss Webster mice. Neurotoxicol Teratol23: 365–372.Search in Google Scholar

Golub MS, Han B, Keen CL, Gershwin ME. (1992). Effects of dietary aluminum excess and manganese deficiency on neurobehavioral endpoints in adult mice. Toxicol Appl Pharmacol112: 154–160.Search in Google Scholar

Gomes LS, Costa JR, Campos MS, Marques MR, Biancardi MF, Taboga SR, Ghedini PC, Santos FCA. (2019). Aluminum disrupts the prenatal development of male and female gerbil prostrate (Meriones unguiculatus). Exp Mol Pathol107: 32–42.Search in Google Scholar

Gomez M, Domingo JL, Llobet JM, Tomas JM, Carbella J. (1986). Short-term oral toxicity study of aluminum in rats. Arch Pharmacol Toxicol12: 145–151.Search in Google Scholar

Gonzalez MA, Alvarez ML, Pisani GB. (2007). Involvement of oxidative stress in the impairment in biliary secretory function induced by intraperitoneal administration of aluminum to rats. Biol Trace Elem Res116: 329–348.Search in Google Scholar

Gonzelez-Suerez I, ÁLvarez-Hernendez D, Carrillo-Lepez N, Naves-Deaz M, Fernendez-Marten JL, Cannata-Andea JB. (2005). Aluminum posttranscriptional regulation of parathyroid hormone synthesis: A role for the calcium-sensing receptor. Kidney Int68(6): 2484–2496.Search in Google Scholar

Gorsky JE, Dietz AA, Spencer H. (1979). Metabolic balance of aluminum in persons receiving aluminum antacids. Clin Chem25: 244–248.Search in Google Scholar

Green BN, Johnson CD, Adams A. (2006). Writing narrative literature reviews for peer-reviewed journals: secrets of the trade. J Chiropr Med5(3): 101–117.Search in Google Scholar

Greger JL. (1992). Dietary and other sources of aluminum intake. In: Aluminum in Biology and Medicine. Ciba Found Symp169: 26–49.Search in Google Scholar

Greger JL, Sutherland J. (1997). Aluminum exposure and metabolism. Critical Review. Clin Lab Sci 34: 439–474.Search in Google Scholar

Guo C, Lu Y, Hsu GSW. (2005). The influence of aluminum exposure on male reproduction and offspring in mice. Environ Toxicol Pharmacol20: 135–141.Search in Google Scholar

Haglin L, Essén-Gustavsson B, Lindholm A. (1994). Hypophosphatemia induced by dietary aluminium hydroxide in growing pigs: effects on erythrocytes, myocardium, skeletal muscle and liver. Acta Vet Scand35(3): 263–271.Search in Google Scholar

Han S, Lemire J, Appanna VP, Auger C, Castonguay Z, Appanna VD. (2013). How aluminium, an intracellular ROS generator, promotes hepatic and neurological diseases: the metabolic tale. Cell Biol Toxicol29(2): 75–84.Search in Google Scholar

Hangouche AJE, Fennich H, Alaika O, Dakka T, Raisouni Z, Oukerraj L, Doghmi N, Cherti M. (2017). Reversible myocadial injury and intraventricular thrombus associated with aluminium phosphide poisoning. Case Rep Cardiol2017, Article ID 6287015, 6 pages, https://doi.org/10.1155/2017/6287015.10.1155/2017/6287015540172328487776Search in Google Scholar

Hansen AB, Ravnskjær L, Loft S, Andersen KK, Bräuner EV, Baastrup R, Yao C, Ketzel M, Becker T, Brandt J, Hertel O, Andersen ZJ. (2016). Long-term exposure to fine particulate matter and incidence of diabetes in the Danish Nurse Cohort. Environ Int91: 243–250.Search in Google Scholar

Harris WR, Messori L. (2002). A comparative study of aluminum (III), gallium (III), indium (III), and thallium (III) binding to human serum transferrin. Coord Chem Rev228: 237–262.Search in Google Scholar

Hasan NA. (2009). Effects of trace elements on albumin and lipoprotein glycation in diabetic retinopathy. Saudi Med J30: 1263–1271.Search in Google Scholar

Hasseeb MM, Al-Hizab AF, Hussein AY. (2011). A histopathologic study of the protective effect of grape seed extract against experimental aluminum toxicosis in male rat. Scient J King Faisal Univ (Basic Appl Sci)12: 283–297.Search in Google Scholar

Hayacibara MF, Queiroz CS, Tabchoury CPM,Cury JA. (2004). Fluoride and aluminum in teas and tea-based beverages. Rev Saude Publica38: 100–105.Search in Google Scholar

He P, Zou Y, Hu Z. (2015). Advances in aluminum hydroxide-based adjuvant research and its mechanism. Hum Vaccin Immunother11(2): 477–488.Search in Google Scholar

Hem SL. (2002). Elimination of aluminum adjuvants. Vaccine20: S40–43.Search in Google Scholar

Hemadi M, Miquel G, Kahn PH, Chahine JME. (2003). Aluminum exchange between citrate and human serum transferrin and interaction with transferrin receptor 1. Biochemistry42: 3120–3130.Search in Google Scholar

Henriksen EJ. (2010). Dysregulation of glycogen synthase kinase-3 in skeletal muscle and the etiology of insulin resistance and type 2 diabetes. Curr Diabetes Rev6(5): 285–293.Search in Google Scholar

Henshaw PF, Bewtra JK, Biswas N. (1993). Occurrence of aluminum, lead, and trihalomethanes in drinking water from the Great Lakes. J Great Lakes Res19: 521–532.Search in Google Scholar

Herbert A, Sterling G, Abraham J, Corrin B. (1982). Desquamative interstitial pneumonia in an aluminum welder. Hum Pathol13(8): 694–699.Search in Google Scholar

Hernández G, Bollini A, Huarte M, Bazzoni G, Piehl L, Chiarotto M, Rubin de Celis E, Rasia M. (2008). In vitro effect of aluminium upon erythrocyte membrane properties. Clin Hemorheol Microcirc40(3): 191–205.Search in Google Scholar

Hewitt CD, Savory J, Wills MR. (1990). Aspects of aluminium toxicity. Clin Lab Med10: 403–422.Search in Google Scholar

His E, Beiras R, Seaman MN, Pagano G, Trieff NM. (1996). Sublethal and lethal toxicity of aluminum industry effluents to early developmental stages of the Crassostrea gigas oyster. Arch Environ Contam Toxicol30: 335–339.Search in Google Scholar

Hofstetter JR, Vincent I, Bugiani O, Richter JA. (1987). Aluminum-induced decreases in choline acetyltransferase, tyrosine hydroxylase and glutamate decarboxylase in selected regions of rabbit brain. Neurochem Pathol6(3): 177–193.Search in Google Scholar

Hogenesch H. (2013). Mechanism of immunopotentiation and safety of aluminum adjuvants. Frontiers Immunol10: 406.Search in Google Scholar

House E, Polwart A, Darbre P, Barr L, Metaxas G, Exley C. (2013). The aluminium content of breast tissue taken from women with breast cancer. Med Biol27(4): 257–266.Search in Google Scholar

Huang W, Wang P, Shen T, Hu C, Han Y, Song M, Bian Y, Li Y, Zhu Y. (2017). Aluminum trichloride inhibited osteoblastic proliferation and downregulated the Wnt/β-catenin pathway. Biol Trace Elem Res177(2): 323–330.Search in Google Scholar

Igbokwe NA. (2016). Characterization of the osmotic stability of Sahel goat erythrocytes in ionic and non-ionic hypotonic media. PhD thesis, Department of Physiology, Pharmacology and Biochemistry, Faculty of Veterinary Medicine, University of Maiduguri, Maiduguri, Nigeria.Search in Google Scholar

Igbokwe NA. (2018). A review of the factors that influence erythrocyte osmotic fragility. Sokoto J Vet Sci16(4): 1–23.Search in Google Scholar

Igwenagu E. (2017). Pathologic effects of oral aluminium administration in non-diabetic and diabetic rats. MVSc dissertation, Department of Veterinary Pathology, University of Maiduguri, Maiduguri, Nigeria.Search in Google Scholar

Igwenagu E, Igbokwe IO, Egbe-Nwiyi TN. (2019). Fasting hyperglycaemia, glucose intolerance and pancreatic islet necrosis in albino rats associated with subchronic oral aluminium chloride exposure. Comp Clin Patholhttp://dx.doi.org/10.1007/s00580-019-03028-4.10.1007/s00580-019-03028-4Search in Google Scholar

Iijima Y, Bando M, Yamasawa H, Moriyama H, Takemura T, Niki T, Sugiyama Y. (2017). A case of mixed dust pneumoconiosis with desquamative interstitial-like reaction in an aluminum welder. Respir Med Case Rep20: 150–153.Search in Google Scholar

Issa AM, Salim MS, Zidan H, Mohamed AF, Farrag AH. (2014). Evaluation of the effects of aluminum phosphate and calcium phosphate nanoparticles as adjuvants in vaccinated mice. Int J Chem Eng Appl5: 367–373.Search in Google Scholar

Jang JH, Surh YJ. (2002). β-Amyloid induces oxidative DNA damage and cell death through activation of c-Jun N terminal kinase. Ann N Y Acad Sci973: 228–236.Search in Google Scholar

Jangra A, Kasbe P, Pandey SN, Dwivedi S, Gurjar SS, Kwatra M, Mishra M, Venu AK, Sulakhiya K, Gogoi R, Sarma N, Bezbaruah BK, Lahkar M. (2015). Hesperidin and silibinin ameliorate aluminum-induced neurotoxicity: modulation of antioxidants and inflammatory cytokines level in mice hippocampus. Biol Trace Elem Res168: 462–471.Search in Google Scholar

Järup L. (2003). Hazards of heavy metal contamination. British Med Bull68: 167–82.Search in Google Scholar

Jederlinic PJ, Abraham JL, Churg A, Himmelstein JS, Epler GR, Gaensler EA. (1990). Pulmonary fibrosis in aluminum oxide workers. Investigation of nine workers with pathologic examination and microanalysis in three of them. Am Rev Respir Dis142(5): 1179–1184.Search in Google Scholar

Jeffery EH, Abreo K, Burgess E, Cannata J, Greger JL. (1996). Systemic aluminum toxicity: effect on bone haematopoietic tissue and kidney. J Toxicol Environ Health46(6): 649–665.Search in Google Scholar

Jones KC, Bennet BG. (1986). Exposure of man to environmental aluminiuman exposure commitment assessment. Sci Total Environ52: 65–82.Search in Google Scholar

Jones K, Linhart C, Haekin C, Exley C. (2017). Urinary excretion of aluminium and silicon in secondary progressive multiple sclerosis. EBioMedicine26: 60–67.Search in Google Scholar

Johnson VJ, Sharma RP. (2003). Aluminum disrupts the pro-inflammatory cytokine/neurotrophin balance in primary brain rotation-mediated aggregate cultures: possible role in neurodegeneration. Neurotoxicology24(2): 261–268.Search in Google Scholar

Jouhanneau P, Raisbeck GM, Yiou F, Lacour B, Banide H, Drueke TB. (1997). Gastrointestinal absorption, tissue retention, and urinary excretion of dietary aluminum determined by using 26Al. Clin Chem43: 1023–1028.Search in Google Scholar

Julka D, Gill KD. (1996). Altered calcium homeostasis: a possible mechanism of aluminium-induced neurotoxicity. Biochem Biophys Acta1315: 47–54.Search in Google Scholar

Kaiser L,Schwartz KA, Burnatowska-Hledin MA. (1984). Microcytic anemia secondary to intraperitoneal aluminum in normal and uremic rats. Kidney Int26: 269–274.Search in Google Scholar

Kamalov J, Carpenter DO, Birman I. (2011). Cytotoxicity of environmentally relevant concentrations of aluminum in murine thymocytes and lymphocytes. J Toxicol2011: 796719.Search in Google Scholar

Kamanyire R, Murray V. (2003). Occupational exposures to fumigants. J Toxicol Clin Toxicol41: 489–490.Search in Google Scholar

Kandimalla R, Thirumala V, Reddy PH. (2017). Is Alzheimer’s disease a type 3 diabetes? A critical appraisal. Biochim Biophys-Mol Basis Dis1863(5): 1078–1089.Search in Google Scholar

Kandimalla R, Vallamkondu J, Corgiat EB, Gill KD. (2016). Understanding aspects of aluminum exposure in Alzheimer’s disease development. Brain Pathol26(2): 139–154.Search in Google Scholar

Katz AC, Frank DW, Sauerhoff MW, Zwicker GM, Freudenthal RI. (1984). A 6-month dietary toxicity study of acidic sodium aluminum phosphate in beagle dogs. Food Chem Toxicol22: 7–9.Search in Google Scholar

Kawahara M, Kato-Negishi M. (2011). Link between aluminum and the pathogenesis of Alzheimer’s disease: The integration of the aluminum and amyloid cascade hypothesis. Int J Alzheimer’s Dis2011: 276393.Search in Google Scholar

Kawahara M, Konoha K, Nagata T, Sadakane Y. (2007). Aluminum and human health: its intake, bioavailability and neurotoxicity. Biomed Res Trace Elem18: 211–220.Search in Google Scholar

Kazi TG, Afridi HI, Kazi N, Jamali MK, Arain MB, Jalbani N, Kandhro GA. (2008). Copper, chromium, manganese, iron, nickel and zinc levels in biological samples of diabetes mellitus patients. Biol Trace Elem Res122: 1–18.Search in Google Scholar

Kazi TG, Jalbani N, Arain MB, Jamali MK, Afridi HI, Shah AQ. (2009). Determination of toxic elements in different brands of cigarette by atomic absorption spectrometry using ultrasonic assisted acid digestion. Environ Monit Assess154(1–4): 155–167.Search in Google Scholar

Keberle H. (1964). The biochemistry of DFO and its relation to iron metabolism. Ann N Y Acad Sci 119: 758–776.Search in Google Scholar

Keith LS, Jones DE, Chou CH. (2002). Aluminum toxicokinetics regarding infant diet and vaccinations. Vaccine20: 13–17.Search in Google Scholar

Kell BD. (2009). Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC Med Genomics2: 1–79.Search in Google Scholar

Khalaf AA, Morgan AM, Mekawy MM, Ali MF. (2007). Developmental toxicity evaluation of oral aluminum in rats. J Egypt Soc Toxicol37: 11–26.Search in Google Scholar

Khattab HAH, Abdallah IZA, Kamel GM. (2010). Grape seed extract alleviate reproductive toxicity caused by aluminium chloride in male rats. J American Sci6: 1200–1209.Search in Google Scholar

Khosla SN, Nand N, Khosla P. (1988). Aluminum phosphide poisoning. J Trop Med Hyg91: 196–198.Search in Google Scholar

Kihira T, Yoshida S, Yase Y, Ono S, Kondo T. (2002). Chronic low-Ca/Mg high–Al diet induces neuronal loss. Neuropathology22: 171–179.Search in Google Scholar

King SW, Savory J, Wills MR, Gitelman HJ. (1981). The clinical biochemistry of aluminum. Crit Rev Clin Lab Sci14: 1–20.Search in Google Scholar

Klaassen CD. (1990). Heavy metals and heavy-metal antagonists, in Goodman and Gilman’s: The Pharmacological Basis of Therapeutics (Gilma AG, Rall TW, Nies AS, Taylor P eds), pp 1592–1614, Pergamon Press, New York.Search in Google Scholar

Klein GL. (2019). Aluminum toxicity to bone: A multisystem effect. Osteoporos Sarcopenia5(1): 2–5.Search in Google Scholar

Klein JP, Mold M, Mery L, Cottier M, Exley C. (2014). Aluminum content of human semen: implications for semen quality. Reprod Toxicol50: 43–48.Search in Google Scholar

Koltz K, Weistenhöfer W, Neff F, Hartwig A, van Thriel C, Drexler H. (2017). The health effects of aluminum exposure. Dtsch Arztebl Int114(39): 653–659.Search in Google Scholar

Konda VR, Eerike M, Chary RP, Arunachalam R, Yeddula VR, Meti V, Devi TS. (2017). Effect of aluminum chloride on blood glucose level and lipid profile in normal, diabetic and treated diabetic rats. Indian J Pharmacol49: 357–365.Search in Google Scholar

Kongerud J, Søyseth V. (2014). Respiratory disorders in aluminum smelter workers. J Occup Environ Med56(5 suppl): S60–70.Search in Google Scholar

Konishi Y, Yagyu K, Kinebuchi H, Salto N, Yamaguchi T, Ohtsuki Y. (1996). Chronic effect of aluminum ingestion on bone in calcium-deficient rats. Basic Clin Pharmacol Toxicol78: 429–434.Search in Google Scholar

Kowalczyk E, Kopff A, Kędziora J, Błaszczyk J, Kopff M, Niedworok J, Fijałkowski P. (2004). Effect of long-term aluminium chloride intoxication on selected biochemical parameters and oxidative-antioxidative balance in experimental animals. Pol J Environ Stud13: 41–43.Search in Google Scholar

Krewski D, Yokel RA, Nieboer E, Borchelt D, Cohen J, Harry J, Kacew S, Lindsay J, Mahfouz AM, Rondeau V. (2007). Human health risk assessment for aluminium, aluminium oxide, and aluminium hydroxide. J Toxicol Environ Health10: 251–269.Search in Google Scholar

Kücük M, Kalayci RB, Cevik A, Elmas I, Kaya M. (2001). Effect of aluminum on the blood-brain barrier permeability in acute and chronically hyperglycaemic rats. Biol Trace Elem Res80 (2): 181–189.Search in Google Scholar

Kumar V, Gill KD. (2014). Oxidative stress and mitochondrial dysfunction in aluminium neurotoxicity and its amelioration. Neurotoxicology41: 154–166.Search in Google Scholar

Lantzy RJ, MacKenzie FT. (1979). Atmospheric trace metals: global cycles and assessment of man’s impact. Geochim Cosmochim Acta43: 511–525.Search in Google Scholar

Lee REJ, Von Lehmden DJ. (1973). Trace metal pollution in the environment. J Air Pollut Control Assoc23: 853–857.Search in Google Scholar

Lefcourt AM, Mesinger JJ. (2001). Effect of adding alum or zeolite to dairy slurry on ammonia volatilization and chemical composition. J Dairy Sci84: 1814–1821.Search in Google Scholar

Lerner A. (2007). Aluminum is a potential envirnmental factor for Crohn’s disease induction: extended hypothsesis. Ann N Y Acad Sci1107: 329–345.Search in Google Scholar

Levine S, Saltzman A, Drakontides AB. (1992). Parenteral aluminum compounds produce a local toxic myopathy in rats: importance of the anion. Toxicol Pathol20(3–1): 405–415.Search in Google Scholar

Levine SN, Sonnier GB, Abreo K. (1990). Effects of diabetes mellitus and aluminum toxicity on myocardial calcium transport. Toxicology65: 137–148.Search in Google Scholar

Lewis RJ. (2001). Hawley’s Condensed Chemical Dictionary, 14th edn, pp. 39–46, Wiley-Interscience, New Jersey, USA.Search in Google Scholar

Li P, Luo W, Zhang H, Zheng X, Liu C, Ouyang H. (2016). Effects of aluminum exposure on bone stimulatory growth factors in rats. Biol Trace Elem Res172(1): 166–171.Search in Google Scholar

Li X, Han Y, Guan Y, Zhang L, Bai C, Li Y. (2012). Aluminum induces osteoblast apoptosis through oxidative stress-mediated JNK signaling pathway. Biol Trace Elem Res150(1–3): 502–508.Search in Google Scholar

Li Y, Liu J, Cao Z. (2015). Effect of sub-chronic aluminum exposure on renal structure in rats. J Northeast Agric Univ22(2): 47–51.Search in Google Scholar

Liaquat L, Sadir S, Batool Z, Tabassum S, Shahzad S, Afzal A, Haider S. (2019). Acute aluminum chloride toxicity revisited: study on DNA damage and histopathological, biochemical and neurochemical alterations in rat brain. Life Sci217: 202–211.Search in Google Scholar

Lidsky TI. (2014). Is the aluminum hypothesis dead? J Occup Environ Med56(5 suppl): S73–S79.10.1097/JOM.0000000000000063413194224806729Search in Google Scholar

Lin CY, Hsiao WC, Huang CJ, Kao CF, Hsu GS. (2013). Heme oxygenase-1 induction by ROS-JNK pathway plays a role in aluminum-induced anemia. J Inorg Chem128: 221–228.Search in Google Scholar

Lin JL, Yang YJ, Yang SS, Leu ML. (1997). Aluminum utensils contribute to aluminum accumulation in patients with renal disease. Am J Kidney Dis30: 653–665.Search in Google Scholar

Linhart C, Talasz H, Morandi EM, Exley C, Lindner HH, Taucher S, Egle D, Hubalek M, Concin N, Ulmer H. (2017). Use of underarm cosmetic products in relation to risk of breast cancer: a case-control study. EBioMedicine21: 78–85.Search in Google Scholar

Lione A. (1983). The prophylactic reduction of aluminum intake. Food Chem Toxicol21: 103–109.Search in Google Scholar

Lione A. (1985). Aluminum toxicity and the aluminum-containing medications. Pharmacol Ther29: 255–285.Search in Google Scholar

Liukkonen-Lilja H, Piepponen S. (1992). Leaching of aluminum from aluminum dishes and packages. Food Addit Contam9: 213–223.Search in Google Scholar

Lukiw WJ, LeBlanc HJ, Carver LA, McLachlan DR, Bazan NG. (1998). Run-on gene transcription in human neocortical nuclei. Inhibition by nanomolar aluminum and implications for neurodegenerative disease. J Mol Neurosci11: 67–78.Search in Google Scholar

Lukiw WJ, Percy ME, Kruck TP. (2005). Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture. J Inorg Biochem99(9): 1895–1898.Search in Google Scholar

Lukyanenko LM, Skarabahatava AS, Slobozhanina EI, Kovaliova SA, Falcioni ML. (2013). In vitro effect of AlCl3 on human erythrocytes: changes in membrane morphology and functionality. J Trace Elem Med Biol27(2): 160–167.Search in Google Scholar

Lyons-Weiler J, Ricketson R. (2018). Reconsideration of the immunotherapeutic pediatric safe dose levels of aluminum. J Trace Elem Med Biol48: 67–73.Search in Google Scholar

Mahieu S, Contini MC, Gonzalez M, Millen N, Elias MM. (2000). Aluminum toxicity. Hematological effects. Toxicol Lett111(3): 235–242.Search in Google Scholar

Mailloux RJ, Hamel R, Appanna VD. (2006). Aluminum toxicity elicits a dys-functional TCA cycle and succinate accumulation in hepatocytes. J Biochem Mol Toxicol20: 198–208.Search in Google Scholar

Mailloux RJ, Lemire J, Appanna VD. (2011). Hepatic response to aluminum toxicity: dyslipidemia and liver diseases. Exp Cell Res317: 2231–2238.Search in Google Scholar

Maitani T, Kubota H, Hori N. (1994). Distribution and urinary excretion of aluminum injected with several organic acids into mice: Relationship with chemical state in serum studied by the HPLC-ICP method. J Appl Toxicol14: 257–261.Search in Google Scholar

Malakoff D. (2000). Aluminum is put on trial as a vaccine booster. Science288: 1323–1234.Search in Google Scholar

Malekshah AK, Torabizadeh Z, Naghshwar F. (2005). Developmental toxicity of aluminum from high doses of AlCl3 in mice. J Appl Res5(4): 575–579.Search in Google Scholar

Malluche HH, Smith AJ, Abreo K, Faugere MC. (1984). The use of deferoxarnme in the management of aluminum accumulation in bone in patients with renal failure. N Engl J Med311: 140–144.Search in Google Scholar

Manello F, Ligi D, Canale M. (2013). Aluminium, carbonyls and cytokines in human nipple aspirate fluids: possible relationship between inflammation, oxidative stress and breast cancer microenvirnment. J Inorg Biochem128: 250–256.Search in Google Scholar

Marítin-Llorens M, Jurado J, Hernández F, Avila J. (2014). GSK-3β, a pivotal kinase in Alzheimer’s disease. Front Mol Neurosci7: 46.Search in Google Scholar

Martin RB. (1992). Aluminum speciation in biology. Ciba Found Symp16: 95–125.Search in Google Scholar

Martin RB, Savory J, Brown S, Bertholf RL, Wills MR. (1987). Transferrin binding to Al and Fe. Clin Chem33: 405–407.Search in Google Scholar

Martinez CS, Escobar AG, Uranga-Ocio JA, Precanba FM, Vassallo DV, Exley C, Miguel M, Wiggers GA. (2017). Aluminum exposure for 60 days at human dietary levels impairs spermatogenesis and sperm quality in rats. Reprod Toxicol73: 128–141.Search in Google Scholar

Martyn CN, Barker DJ, Osmond C, Harris EC, Edwardson JA, Lacey RF. (1989). Geographical relation between Alzheimer’s disease and aluminum in drinking water. Lancet1: 59–62.Search in Google Scholar

Mathiyazahan DB, Thenmozhi AJ, Manivasagam T. (2015). Protective effect of black tea extract against aluminium chloride-induced Alzheimer’s disease in rats. A behavioural, biochemical and molecular approach. J Funct Foods16: 423–435.Search in Google Scholar

Maya S, Prakash T, Madhu KD, Goli D. (2016). Multifaceted effects of aluminium in neurodegenerative diseases: a review. Biomed Pharmacother83: 746–754.Search in Google Scholar

Mayor GH, Lohr TO, Sanchez TV. (1985). Aluminum metabolism and toxicity in renal failure: A review. J Environ Pathol Toxicol Oncol6: 43–50.Search in Google Scholar

Mehrpour O, Alfred S, Shadnia S, Keyler DE, Soltaninejad K, Chalaki N, Sedaghat M. (2008). Hyperglycemia in acute aluminum phosphide poisoning as a potential prognostic factor. Hum Exp Toxicol27: 591–595.Search in Google Scholar

Meliker JR, Wahi RL, Cameron LL, Nriagu JO. (2007). Arsenic in drinking water and cerebrovascular disease, diabetes mellitus, and kidney disease in Michigan: a standardized mortality ratio analysis. Environ Health6: 1–11.Search in Google Scholar

Menke A, Casagrande S, Geiss L, Cowie CC. (2015). Prevalence of and trends in diabetes among adults in the United States, 1988–2012. J Am Med Assoc314(10): 1021–1029.Search in Google Scholar

Mestaghanmi H, El Amrani S, Dauca M, Saile R. (2003). Effect of aluminium chloride on pregnant rats and their offspring. Sciences et Techniques de l’Animal de Laboratoire28(1): 43–51.Search in Google Scholar

Miller RR, Churg AM, Hutcheon M, Lom S. (1984). Pulmonary aveolar proteinosis and aluminum dust exposure. Am Rev Respir Dis130(2): 312–315.Search in Google Scholar

Miller ZN. (2016). Aluminum in childhood vaccines is unsafe. J Am Phys Surg21(4): 109–117.Search in Google Scholar

Milnerowicz H, Ściskalska M, Dul M. (2015). Pro-inflammatory effects of metals in persons and animals exposed to tobacco smoke. J Trace Elem Med Biol29: 1–10.Search in Google Scholar

Mirhashemi SM, Aarabi MH. (2011). To study various concentrations of magnesium and aluminium on amylin hormone conformation. Pak J Biol Sci14(11): 653–657.Search in Google Scholar

Mirhashemi SM, Shahabaddin M-E. (2011). Evaluation of aluminium, manganese, copper and selenium effects on human islets amyloid polypeptide hormone aggregation. Pak J Biol Sci14(4): 288–292.Search in Google Scholar

Mirza A, King A, Troakes C, Exley C. (2017). Aluminium in brain tissue in familial Alzheimer’s disease. J Trace Elem Med Biol40: 30–36.Search in Google Scholar

Miska-Schramm A, Kapusta A, Kruczek M. (2017). The effect of aluminum exposure on reproductive ability of the bank vole (Myodes glareolus). Biol Trace Elem Res177(1): 97–106.Search in Google Scholar

Mitkus RJ, King DB, Hess MA, Forshee RA, Walderhaug MO. (2011). Updated aluminum pharmacokinetics following infant exposures through diet and vaccination. Vaccine29(51): 9538–9543.Search in Google Scholar

Mittal K, Katare DP. (2016). Shared links between type 2 diabetes mellitus and Alzheimer’s disease: A review. Diabetes Metab Syndr10(2 Suppl 1): S144–S149.Search in Google Scholar

Miu AC, Benga O. (2006). Aluminum and Alzheimer’s disease: a new look. J Alzheimers Dis10(2–3): 179–201.Search in Google Scholar

Moghadamnia AA. (2012). An update on toxicology of aluminum phosphide. DARU J Pharm Sci20: 1–8.Search in Google Scholar

Mohammed A, Mayyas I, Elbetieha A, Shoter A, Khamas W, Alnasser Z. (2008). Toxicity evaluation of aluminium chloride on adult female mice. J Anim Vet Adv7(5): 552–556.Search in Google Scholar

Mold M, Umar D, King A, Exley C. (2018). Aluminium in brain tissue in autism. J Trace Elem Med Biol46: 76–82.Search in Google Scholar

Moore PA, Daniel TC,Edwards DR. (1999). Reducing phosphorus runoff and improving poultry production with alum. Poult Sci78: 692–698.Search in Google Scholar

Moore PA, Daniel TC,Edwards DR. (2000). Reducing phosphorus runoff and inhibiting ammonia loss from poultry manure with aluminum sulfate. J Environ Qual29: 37–49.Search in Google Scholar

Morris G, Puri BK, Frye RE. (2017). The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. How strong is the evidence and what could be the mechanism involved? Metab Brain Dis32(5): 1335–1355.Search in Google Scholar

Morrissey J, Rothstein M, Mayor G, Slatopolsky E. (1983). Suppresion of parathyroid hormone secretion by aluminum. Kidney Int23(5): 699–704.Search in Google Scholar

Mouro VGS, Menezes TP, Lima GDA, Domingues RR, Souza AC, Oiveira JA, Matta SLP, Machado-Neves M. (2017). How bad is aluminum exposure to reproductive parameters? Biol Trace Elem Res Sept 8. Doi: 10.1007/s12011-017-1139-3.10.1007/s12011-017-1139-328887675Search in Google Scholar

Mujika JI, Torre GD, Formoso E, Grande-Aztatzi R, Grabowski SJ, Exley C, Lopex X. (2018). Aluminum’s preferential binding site in proteins: sidechain of amino acids versus backbone interactions. J Inorg Biochem181: 111–116.Search in Google Scholar

Muselin F, Cristina RT, Iqna V, Dumitrescu E, Brezovan D, Trif A. (2016). The consequences of aluminium intake on reproductive function in male rats: a three-generation study. Turk J Med Sci46: 1240–1248.Search in Google Scholar

Nam SM, Kim JW, Yoo DY, Kim W, Jung HY, Hwang IK, Seong JK, Yoon YS. (2014). Additive or synergistic effects of aluminum on the reduction of neural stem cells, cell proliferation and neuroblast differentiation in the dentate gyrus of high-fat diet-fed mice. Biol Trace Elem Res157 (1): 51–59.Search in Google Scholar

Nam SM, Kim JW, Yoo DY, Jung HY, Choi JH, Hwang IK, Seong JK, Yoon YS. (2016). Reduction of adult hippocampal neurogenesis is amplified by aluminium exposure in a model of type 2 diabetes. Journal of Veterinary Science17(1): 13–20.Search in Google Scholar

Nasu T, Suzuki N. (1998). Effect of aluminum ions on K+-induced contraction in ileal longitudinal smooth muscle. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol120(1): 137–143.Search in Google Scholar

Nayak P. (2002). Aluminum: impacts and disease. Environ Res89: 101–115.Search in Google Scholar

Navas-Acien A, Silbergeld EK, Pastor-Barriuso R, Guallar E. (2009). Rejoinder: arsenic exposure and prevalence of type 2 diabetes: updated findings from the National Health Nutrition and Examination Survey, 2003–2006. Epidemiology20: 816–820.Search in Google Scholar

Neiva TJC, Fries DM, Monteiro HP, D’Amico EA, Chamone DAF. (1997). Aluminum induces lipid peroxidation and aggregation of human blood platelets. Braz J Med Biol Res30: 599–604.Search in Google Scholar

Nelson WO, Campbell PGC. (1991). The effects of acidification on the geo-chemistry of Al, Cd, Pb, and Hg in freshwater environments: a literature review. Environ Pollut71: 91–130.Search in Google Scholar

Netterlid E, Hindsén M, Siemund I, Björk J, Werner S, Jacobsson H, Güner N, Bruze M. (2013). Does allergen-specific immunotherapy induce contact allergy to aluminim? Acta Derm Venereol93: 50–56.10.2340/00015555-140922948339Search in Google Scholar

Newairy AS, Salama AF, Hussien HM, Yousef MI. (2009). Propolis alleviates aluminum-induced lipid peroxidation and biochemical parameters in male rats. Food Chem Toxicol47: 1093–1098.Search in Google Scholar

Ng M. (2004). Role of hydrogen peroxide in the aetiology of Alzheimer’s disease: Implications for treatment. Drugs Aging21: 81–100.Search in Google Scholar

Niemoeller OM, Kiedaisch V, Dreischer P, Wieder T, Lang F. (2006). Stimulation of eryptosis by aluminum ions. Toxicol Appl Pharmacol217(2): 168–175.Search in Google Scholar

Nikolov IG, Joki N, Vicca S, Patey N, Auchere D, Benchitrit J. (2010). Tissue accumulation of lanthanum as compared to aluminum in rats with chronic renal failure: possible harmful effects after long-term exposure. Nephron Exp Nephrol115: 112–121.Search in Google Scholar

Nordal KP, Dahl E, Albrechtsen D, Halse J, Leivestad T, Tretli S, Flatmark A. (1988). Aluminum accumulation and immunosuppressive effect in recipients of kidney transplants. Br Med J287: 1581–1582.Search in Google Scholar

Obukhova T, Budkar’ LN, Tereshina LG, Karpova EA. (2015). [Dissociation of disorders of carbohydrate and lipid metabolism in aluminum industry workers according to medical examination data] in Russian. Gig Sanit94 (2): 67–69.Search in Google Scholar

Ogborn MR, Dorcas VC, Crocker JF. (1991). Deferoxamine and aluminum clearance in pediatric hemodialysis patients. Pediatr Nephrol5: 62–64.Search in Google Scholar

Ohsaka Y, Nomura Y. (2016). Rat white adipocytes activate p85/p110 P13K and induce PM GLUT4 response to adrenoceptor agonists or aluminum fluoride. Physiol Int103(1): 35–48.Search in Google Scholar

Omar HM, Khadiga AH, Abd-Elghaffar SK, Ahmed EA. (2003). Aluminium toxicity in rats: the role of tannic acid as antioxidant. Assiut Univ Bull Environ Res6: 1–14.Search in Google Scholar

Ondov JM, Zoller WH, Gordon GE. (1982). Trace element emissions of aerosols from motor vehicles. Environ Sci Technol16: 318–328.Search in Google Scholar

Oneda S, Takasaki T, Kuriwaki K, Ohi Y, Umekita Y, Hatanaka S, Fujiyoshi T, Yoshida A, Yoshida H. (1994). Chronic toxicity and tumorigenicity study of aluminum potassium sulfate in B6C3F1 mice. In Vivo8: 271–278.Search in Google Scholar

Orihuela D. (2007). Effect of aluminium on duodenal calcium transport in pregnant and lactating rats treated with bromocriptine. J Inorg Biochem101(9): 1270–1274.Search in Google Scholar

Orihuela D. (2011). Aluminium effects on thyroid gland function: iodide up-take, hormone biosynthesis and secretion. J Inorg Biochem105(11): 1464–1468.Search in Google Scholar

Osama A, Fatma A, Mohamed E, Huda S. (2014). Studies on the protective effects of ginger extract and in combination with ascorbic acid against aluminum toxicity induced hematological disorders, oxidative stress and hepatorenal damage in rats. Ann Vet Anim Sci1: 136–150.Search in Google Scholar

Osman HM, Shayoub ME, Babiker EM, Osman B, Elhassan AM. (2012). Effect of ethanolic leaf extract of Moringa oleifera on aluminum-induced anemia in white albino rats. Jordan J Biol Sci5: 255–260.Search in Google Scholar

Oteiza PI. (1994). A mechanism for the stimulatory effect of aluminum on iron-induced lipid peroxidation. Arch Biochem Biophys308: 374–379.Search in Google Scholar

Oteiza PI, Fraga C, Keen CL. (1993a). Aluminum has both oxidant and antioxidant effects in mouse brain membranes. Arch Biochem Biophys300: 517–521.10.1006/abbi.1993.10708424688Search in Google Scholar

Oteiza PI, Keen CL, Han B, Golub MS. (1993b). Aluminum accumulation and neurotoxicity in Swiss-Webster mice after long-term dietary exposure to aluminum and citrate. Metabolism42: 1296–1300.10.1016/0026-0495(93)90128-BSearch in Google Scholar

Owen LM, Crews HM, Bishop NJ, Massey RC. (1994). Aluminum uptake from some foods by guinea pigs and the characterization of aluminum in in vivo intestinal digesta by SEC-ICP-MS. Food Chem Toxicol32: 697–705.Search in Google Scholar

Oztürk B, Ozdemir S. (2015). Effects of aluminum chloride on some trace elements and erythrocyte osmotic fragility in rats. Toxicol Ind Health31(12): 1069–1077.Search in Google Scholar

Pandey G, Jain GC. (2013). A review on toxic effects of aluminium exposure on male reproductive system and probable mechanisms of toxicity. Intl J Toxicol Appl Pharmacol3(3): 48–57.Search in Google Scholar

Pappas RS. (2011). Toxic elements in tobacco and cigarette smoke: inflammation and sensitization. Metallomics3(11): 1181–1198.Search in Google Scholar

Pennington JA. (1988). Aluminum content of foods and diets. Food Addit Contam5: 161–232.Search in Google Scholar

Pennington JA,Schoen SA. (1995). Estimates of dietary exposure to aluminium. Food Addit Contam12: 119–128.Search in Google Scholar

Perez G, Garbossa G, Nesse A. (2001). Disturbance of cellular iron uptake and utilization by aluminum. J Inorg Biochem87: 21–27.Search in Google Scholar

Pettersen JC, Hackett DS, Zwicker GM,Sprague GL. (1990). Twenty-six week toxicity study with KASAL (basic sodium aluminum phosphate) in beagle dogs. Environ Geochem Health12: 121–123.Search in Google Scholar

Pineau A, Fauconneau B, Sappino A-P, Deloncle R, Guillard O. (2014). If exposure to aluminium in antiperspirants presents health risk, its content should be reduced. J Trace Elem Med Biol28(2): 147–150.Search in Google Scholar

Pivnick EK, Kerr NC, Kaufman RA, Jones DP, Chesney RW. (1995). Rickets secondary to phosphate depletion: a sequela of antacid use in infancy. Clin Pediatr34: 73–78.Search in Google Scholar

Pogue AI, Jaber V, Zhao Y, Lukiw WJ. (2017). Systemic inflammation in C57BL/6J mice receiving dietary aluminum sulfate; up-regulation of the pro-inflammatory cytokines IL-6 and TNFα, C-reactive protein (CRP) and miRNA-146a in blood serum. J Alzheimers Dis Parkinsonism7(6): 403. doi: 10.4172/2161-0460.1000403.10.4172/2161-0460.1000403577142829354323Search in Google Scholar

Pogue Ai, Lukiw WJ. (2016). Aluminium, the genetic apparatus of human CNS and Alzheimer’s disease. Morphologie100(329): 56–64.Search in Google Scholar

Pratico D, Uryu K, Sung S, Tang S, Trojanowski JQ, Lee VM. (2002). Aluminum modulates brain amyloidosis through oxidative stress APP transgenic mice. FASEB J16: 1138–1140.Search in Google Scholar

Priest ND, Talbot RJ, Austin JG, Day JP, King SJ, Fifield K, Cresswell RG. (1996). The bioavailability of 26Al-labelled aluminium citrate and aluminium hydroxide in volunteers. Biometals9: 221–228.Search in Google Scholar

Pun KK, Ho PWM, Lau P. (1990). Effect of aluminum on the parathyroid hormone receptors of bone and kidney. Kidney Int37(1): 72–78.Search in Google Scholar

Que Hee SS, Finelli VN, Fricke FL,Wolnik KA. (1982). Metal content of stack emissions, coal and fly ash from some eastern and western power plants in the U.S.A. as obtained by ICP-AES. Int J Environ Anal Chem13: 1–18.Search in Google Scholar

Qureshi N, Malmberg RH. (1985). Reducing aluminum residuals in finished water. J Am Water Works Assoc77: 1–18.Search in Google Scholar

Ranau R, Oehlenschlager J, Steinhart H. (2001). Aluminium levels of fish fillets baked and grilled in aluminium foil. Food Chem73: 1–6.Search in Google Scholar

Ranjbar A, Khani-Jazani R, Sedighi A, Jalali-Mashayekhi F, Ghazi-Khansari M, Abdollahi M. (2008). Alteration of body total antioxidant capacity and thiol molecules in human chronic exposure to aluminum. Toxicol Environ Chem90: 707–713.Search in Google Scholar

Ravi SK, Ramesh BN, Mundugaru R, Vincent B. (2018). Multiple pharmacological activities of Caesalpinia crista against aluminium-induced neurodegeneration in rats: Relevance for Alzheimer’s disease. Environ Toxicol Pharmacol58: 202–211.Search in Google Scholar

Razniewska G, Trzcinka-Ochocka M. (2003). ET-AAS as a method for determination of aluminum in blood serum and urine. Chem Anal48: 107–113.Search in Google Scholar

Reinke CM, Breitkreutz J, Leuenberger H. (2003). Aluminum in over the-counter drugs: risks outweigh benefits. Drug Saf26: 1011–1025.Search in Google Scholar

Reto M, Figueira ME, Filipe HM, Almeida CM. (2007). Chemical composition of green tea (Camellia sinensis) infusions commercialized in Portugal. Plant Foods Hum Nutr62: 139–144.Search in Google Scholar

Reza SM, Palan MJ. (2006). Effect of aluminium on testosterone hormones in male rat. J Med Sci6(2): 296–299.Search in Google Scholar

Rigolet M, Aouizerate J, Couette M, Ragunathan-Thangarajah N, Aoun-Sebaiti M, Gherardi RK, Cadusseau C, Authier FJ. (2014). Clinical features in patients with long-lasting macrophagic myofasciitis. Front Neurol doi: 10.3389/fneur.2014.00230.10.3389/fneur.2014.00230424668625506338Search in Google Scholar

Rim K. (2007). Aluminum leaching using chelating agent as a composition food. Food Chem Toxicol45: 1688–1693.Search in Google Scholar

Rodríguez J, Mandlunis PM. (2018). A review of metal exposure and its effects on bone health. J Toxicol2018, Article ID 4854152, 11 pages.10.1155/2018/4854152632351330675155Search in Google Scholar

Rosseland BO, Eidhuset TD, Staurnes M. (1990). Environmental effects of aluminum. Environ Geochem Health12: 17–27.Search in Google Scholar

Sadhana S. (2011). S-Allyl-Cysteines reduce amelioration of aluminum induced toxicity in rats. Am J Biochem Biotechnol7: 74–83.Search in Google Scholar

Saiyed SM, Yokel RA. (2005). Aluminum content of some foods and food products in the USA, with aluminum food additives. Food Addit Contam22: 234–244.Search in Google Scholar

Sakajiri T, Yamamura T, Kikuchi T, Ichimura K, Sawada T, Yajima H. (2010). Absence of binding between the human transferrin receptor and the transferrin complex of biological toxic trace element, aluminum, because of an incomplete open/closed form of the complex. Biol Trace Elem Res136: 279–286.Search in Google Scholar

Sakamoto T, Saito H, Ishii K, Takahashi H, Tanabe S, Ogasawara Y. (2006). Aluminum inhibits proteolytic degradation of amyloid beta peptide by cathepsin D: a potential link between aluminum accumulation and neuritic plaque deposition. FEBS Lett580: 6543–6549.Search in Google Scholar

Savory J, Exley C, Forbes WF, Huang Y, Joshi JG, Kruck T, McLachlan DR, Wakayama I. (1996). Can the controversy of the role of aluminum in Alzheimer’s be resolved? What are the suggested approaches to this controversy and methodological issues to be considered? J Toxicol Environ Health48: 615–635.10.1080/0098410961611048772802Search in Google Scholar

Schroeder HA, Mitchener M. (1975a). Life-term studies in rats: effects of aluminum, barium, beryllium and tungsten. J Nutr105: 421–427.10.1093/jn/105.4.4211113208Search in Google Scholar

Schroeder HA, Mitchener M. (1975b). Life-term effects of mercury, methyl-mercury, and nine other trace metals on mice. J Nutr105: 452–458.10.1093/jn/105.4.4521113210Search in Google Scholar

Sedman AB, Klein GL, Merritt RJ, Weber KO, Gill WL, Anand H, Alfrey AC. (1985). Evidence of aluminum loading in infants receiving intravenous therapy. N Engl J Med312(21): 1337–1343.Search in Google Scholar

Sepe A, Costantini S, Ciaralli L, Ciprotti M, Giordano R. (2001). Evaluation of aluminium concentrations in samples of chocolate and beverages by electrothermal atomic absorption spectrometry. Food Addit Contam18: 788–796.Search in Google Scholar

Serdar MA, Bakir F, Hasimi A, Celik T, Akin O, Kenar L, Aykut O, Yildirimkaya M. (2009). Trace and toxic element patterns in nonsmoker patients with non-insulin-dependent diabetes mellitus, impaired glucose tolerance, and fasting glucose. Int J Diabetes Dev Ctries29: 35–40.Search in Google Scholar

Shadnia S, Mehrpour O, Abdollahi M. (2008). Unintentional poisoning by phosphine released from aluminum phosphide. Hum Exp Toxicol27: 87–89.Search in Google Scholar

Shahraki MR, Mony EYP, Asl SZ, Sarkaki AR, Shahraki AR. (2008). Effects of aluminium chloride injection in lateral ventricles on serum gonadothropines, testosterone and spermatogenesis in rats. J Med Sci8(4): 410–414.Search in Google Scholar

Sharma DR, Wani WY, Sunkaria A, Kandimalla RJ, Sharma RK, Verma D, Bal A, Gill KD. (2016). Quercetin attenuates neuronal death against aluminum-induced neurodegeneration in rat hippocampus. Neuroscience324: 163–176.Search in Google Scholar

Shati AA, Alamri SA. (2010). Role of saffron (Crocus sativus L.) and honey syrup on aluminum-induced hepatotoxicity. Saudi Med J31: 1106–1113.Search in Google Scholar

Shaw CA, Li D, Tomljenovic L. (2014). Are there negative CNS impacts of aluminum adjuvants used in vaccines and immunotherapy. Immunotherapy6(10): 1055–1077.Search in Google Scholar

She Y, Wang N, Chen C, Zhu Y, Xia S, Hu C, Li Y. (2012). Effects of aluminum on immune functions of cultured splenic T and B lymphocytes in rats. Biol Trace Elem Res147(1–3): 246–250.Search in Google Scholar

Sherrard DJ, Ott SM, Andress DL. (1985). Pseudohyperparathyroidism syndrome associated with aluminum intoxication in patients with renal failure. Am J Med79(1): 127–130.Search in Google Scholar

Shirley DG, Lote CJ. (2005). Renal Handling of Aluminium. Nephron Physiol100: 99–103.Search in Google Scholar

Singh T, Goel RK. (2015). Neuroprotective effect of Allium cepa L. in aluminium chloride induced neurotoxicity. NeuroToxicology49: 1–7.Search in Google Scholar

Skarabahatava AS, Lukyanenko LM, Slobozhanina EI, Falcioni ML, Orlando P, Silvestri S, Tiano L, Falcioni G. (2015). Plasma and mitochondrial membrane perturbation induced by aluminum in human peripheral blood lymphocytes. J Trace Elem Med Biol31: 37–44.Search in Google Scholar

Song M, Huo H, Cao Z, Han Y, Gao L. (2017). Aluminum trichloride inhibits the rat osteoblast mineralization in vitro. Biol Trace Elem Res175(1): 186–193.Search in Google Scholar

Soni MG, White SM, Flamm WG, Burdock GA. (2001). Safety evaluation of dietary aluminum. Regul Toxicol Pharmacol33: 66–79.Search in Google Scholar

Sorenson JRJ, Campbell IR, Tepper LB,Lingg RD. (1974). Aluminum in the environment and human health. Environ Health Perspect8: 3–95.Search in Google Scholar

Sorgdrager B, Looff AJ, Monchy JG, Pal TM, Dubois AE, Rijcken B. (1998). Occurrence of occupational asthma in aluminum potroom workers in relation to preventative measures. Int Arch Occup Environ Health71: 53–59.Search in Google Scholar

Stahl T, Taschan H, Brunn H. (2011). Aluminium content of selected foods and food products. Environ Sci Eur23(37): 1–11.Search in Google Scholar

Steinhausen C, Kislinger G, Winklhofer C. (2004). Investigation of the aluminum biokinetics in humans: a 26Al tracer study. Food Chem Toxicol42: 363–371.Search in Google Scholar

Stone CJ, McLaurin DA, Steinhagen WH, Cavender FL, Haseman JK. (1979). Tissue deposition patterns after chronic inhalation exposures of rats and guinea pigs to aluminum chlorhydrate. Toxicol Appl Pharmacol49: 71–76.Search in Google Scholar

Sun H, Hu C, Jia L, Zhu Y, Zhao H, Shao B, Wang N, Zhang Z, Li Y. (2011). Effects of aluminum exposure on serum sex hormones and androgen receptors expression in male rats. Biol Trace Elem Res144(1–3): 1050–1058.Search in Google Scholar

Sun X, Cao Z, Zhang Q, Han L, Li Y. (2016a). Aluminum chloride inhibits osteo-blast mineralization via TGF-β1/Smad signaling pathway. Chem Biol Interact244: 9–15.10.1016/j.cbi.2015.11.02726658030Search in Google Scholar

Sun X, Cao Z, Zhang Q, Liu S, Xu F, Che J, Zhu Y, Li, Y, Pan C, Liang W. (2015). Aluminum trichloride impairs bone and downregulates Wnt/β-catenin signaling pathway in young growing rats. Food Chem Toxicol86: 154–162.Search in Google Scholar

Sun X, Liu J, Zhuang C, Yang X, Han Y, Shao B, Song M, Li Y, Zhu Y. (2016b). Aluminum trichloride induces bone impairment through TGF-β1/Smad signaling pathway. Toxicology371: 49–57.10.1016/j.tox.2016.10.00227720690Search in Google Scholar

Sun X, Sun H, Yu K, Wang Z, Liu Y, Liu K, Zhu Y, Li Y. (2018). Aluminum chlo-ride causes the dysfunction of testes through inhibiting ATPase enzyme activities and gonadotropin receptor expression in rats. Biol Trace Elem Res183(2): 296–304.Search in Google Scholar

Sun X, Wang H, Huang W, Yu H, Shen T, Song M, Han Y, Li Y, Zhu Y. (2017). Inhibition of bone formation in rats by aluminum exposure via Wnt/β-catenin pathway. Chemosphere176: 1–7.Search in Google Scholar

Sumathi T, Shobana C, Mahalakshmi V, Sureka R, Subathra M, Vishali A, Rekha K. (2013). Oxidative stress in brains of male rats intoxicated with aluminium and neuromodulating effect of Celastrus paniculatus alcoholic seed extract. Asian J Pharm Clin Res6: 80–90.Search in Google Scholar

Sushma NJ, Sivaiah U, Suraj NJ, Rao KJ. (2007). Aluminium acetate: role in oxidative metabolism of albino mice. Int Zool Res3(1): 48–52.Search in Google Scholar

Suwalsky M, Norris B, Villena F, Cuevas F, Sotomayor P, Zatta P. (2004). Aluminium fluoride affects the structure and functions of cell membrane. Toxicology42(6): 925–933.Search in Google Scholar

Taїr K, Kharoubi O, Taїr OA, Hellal N, Benyettou I, Aoues A. (2016). Aluminium-induced acute neurotoxicity in rats: Treatment with aqueous extract of Arthrophytum (Hammada scoparia). J Acute Dis5(6): 470–482.Search in Google Scholar

Taiwo OA. (2014). Diffuse parenchymal diseases associated with aluminium use and primary aluminum production. J Occup Environ Med55(5 suppl): S71–S72.Search in Google Scholar

Taiwo OA, Sircar KD, Slade MD, Cantley LF, Vegso SJ, Rabinowitz PM, Fiellin MG, Cullen MR. (2006). Incidence of asthma among aluminum workers. J Occup Environ Med48(3): 275–282.Search in Google Scholar

Tanabe K, Liu Z, Patel S, Doble BW, Li L, Cras-Méneur C, Martinez SC, Welling CM, White MF, Bernal-Mirzrachi E, Woodgett JR, Permutt MA. (2008). Genetic deficiency of glycogen synthase kinase-3β corrects diabetes in mouse models of insulin resistance. PLoS Biology6(2): e37.Search in Google Scholar

Teraoka H. (1981). Distribution of 24 elements in the internal organs of normal males and the metallic workers in Japan. Arch Environ Health36: 155–164.Search in Google Scholar

Thompson KH, Orvig C. (2006). Vanadium in diabetes: 100 years from phase 0 to phase I. J Inorg Biochem100: 1925–1935.Search in Google Scholar

Thomson SM, Burnet DC, Bergmann JD, Hixson CJ. (1986). Comparative inhalation hazards of aluminum and brass powders using bronchopulmonary lavage as an indicator of lung damage J Appl Toxicol6: 197–209.10.1002/jat.25500603113722713Search in Google Scholar

Tomasello MF, Sinopoli A, Pappalardo G. (2015). On the environmental factors affecting the structural and cytotoxic properties of IAPP peptides. J Diabetes Res2015: 918573.Search in Google Scholar

Tomljenovic L, Shaw CA. (2011). Aluminum vaccine adjuvants: are they safe? Curr Med Chem18: 2630–2637.10.2174/09298671179593374021568886Search in Google Scholar

Toyokuni S. (2002). Iron and carcinogenesis: From fenton reaction to target genes. Redox Rep4: 189–197.Search in Google Scholar

Trieff NM, Romana LA, Esposito A, Oral R, Quiniou F, Iaccarino M, Alcock N, Ramanujam VMS, Pagano G. (1995). Effluent from bauxite factory induces developmental and reproductive damage in sea urchins. Arch Environ Contam Toxicol28: 173–177.Search in Google Scholar

Türkez H, Geyikoglu F, Colak S. (2011). The protective effect of boric acid in aluminum-induced hepatotoxicity and genotoxicity in rats. Turk J Biol35: 293–301.Search in Google Scholar

Türkez H, Yousef MI, Geyikoglu F. (2010). Propolis prevents aluminium-induced genetic and hepatic damages in rat liver. Food Chem Toxicol48(10): 2741–2746.Search in Google Scholar

Valkonen S Aitio A. (1997). Analysis of aluminum in serum and urine for the biomonitoring of occupational exposure. Sci Total Environ199: 103–110.Search in Google Scholar

van Landeghem GF, D’Haese PC, Lamberts LV, DebBroe ME. (1994). Quantitative HPLC/ETAAS hybrid method with an on-line metal scavenger for studying the protein binding and speciation of aluminum and iron. Anal Chem66: 216–222.Search in Google Scholar

van Rensburg SJ, Carstens ME, Potocnik FCV, Aucamp AK, Taljaard JJF, Koch KR. (1992). Membrane fluidity of platelets and erythrocytes in patients with Alzheimer’s disease and the effect of small amounts of aluminium on platelet and erythrocyte membranes. Neurochem Res17(8): 825–829.Search in Google Scholar

Vandenplas O, Delwiche JP, Vanbilsen ML, Joly J, Roosels D. (1998). Occupational asthma caused by aluminum welding. Eur Respir J11: 1182–1184.Search in Google Scholar

Vasanthan S, Joshi P. (2018). Effect of aluminum toxicity and Bacopa monnieri on plasma cortisol level in Wistar albino rats. Natl J Physiol Pharm Pharmacol8(8): 1088–1091.Search in Google Scholar

Verma SK, Ahmad S, Shirazi N, Barthwal SP, Khurana D, Chugh M, Gambhir HS. (2007). Acute pancreatitis: a lesser-known complication of aluminum phosphide poisoning. Hum Exp Toxicol26: 979–981.Search in Google Scholar

Vignal C, Desreumaux P, Body-Malapel M. (2016). Gut: An underestimated target organ for aluminium. Morphologie100(329): 75–84.Search in Google Scholar

Vittori D, Garbossa G, Lafourcade C, Pérez G, Nesse A. (2002). Human erythroid cells are affected by aluminium. Alteration of membrane band 3 protein. Biochim Biophys Acta Biomembr1558(2): 142–150.Search in Google Scholar

Vittori D, Nesse A, Pérez G, Garbossa G. (1999). Morphologic and functional alterations of erythroid cells induced by long-term ingestion of aluminum. J Inorg Biochem76: 113–120.Search in Google Scholar

Vittori D, Pregi N, Pérez G, Garbossa G, Nesse A. (2005). The distinct erythropoietin functions that promote cell survival and proliferation are affected by aluminum exposure through mechanisms involving erythropoietin receptor. Biochim Biophys Acta1743(1–2): 29–36.Search in Google Scholar

Vorbrodt AW, Trowbridge RS, Drobrogowska DH. (1994). Cytochemical study of the effect of aluminium on cultured brain microvascular endothelial cells. Histochem J26(2): 119–126.Search in Google Scholar

Vota DM, Crisp RL, Nesse AB, Vittori DC. (2012). Oxidative stress due to aluminum exposure induces eryptosis which is prevented by erythropoietin. J Cell Biochem113(5): 1581–1589.Search in Google Scholar

Wang N, She Y, Zhu Y, Zhao H, Shao B, Sun H, Hu C, Li Y. (2012). Effects of sub-chronic aluminum exposure on the reproductive function of female rats. Biol Trace Elem Res145(3): 382–387.Search in Google Scholar

Wang X, Xi Y, Zeng X, Zhao H, Cao J, Jiang W. (2018). Effect of chlorogenic acid against aluminium neurotoxicity in ICR mice through chelation and anti-oxidant actions. J Funct Foods40: 365–376.Search in Google Scholar

Wang Z, Wei X, Yang J, Suo J, Chen J, Liu X, Zhao X. (2016). Chronic exposure to aluminum and risk of Alzheimer’s disease: a meta-analysis. Neurosci Lett610: 200–206.Search in Google Scholar

Warady BA, Ford DM, Gaston CE, Sedrnan AB, Huffer WE, Lum GM. (1986). Aluminum intoxication in a child: treatment with intraperitoneal desferrioxamine. Pediatrics78: 651–655.Search in Google Scholar

Ward R, Zhang Y, Crichton RR. (2001). Aluminum toxicity and iron homeostasis. J Inorg Biochem87: 9–14.Search in Google Scholar

Wei H, Wang MD, Meng LX. (2012). Laurel West aluminum industial base residents trace element content in serum and its associated abnormal glucose metabolism (J). Xian dai Yu fang Yi xue (Modern Prev Med)4: 065.Search in Google Scholar

Wei X, Wei H, Yang D, Li D, Yang X, He M, Lin E, Wu B. (2018). Effect of aluminum exposure on glucose metabolism and its mechanism in rats. Biol Trace Elem Reshttps://doi.org/10.1007/s12011-018-1318-x First online 28 March 2018.10.1007/s12011-018-1318-x29589267Search in Google Scholar

Wesdock JC, Arnold IMF. (2014). Occupational and environmental health in the aluminum industry. J Occup Environ Med56(5 suppl): S5–11.Search in Google Scholar

Westermark P, Andersson A, Westermark GT. (2011). Islet amyloid polypeptide, islet amyloid and diabetes mellitus. Physiol Rev91(3): 795–826.Search in Google Scholar

Willhite CC, Karyakina NA, Yokel RA, Yenugadhati N, Wisniewski TM, Arnold IMF, Momoli F, Krewski D. (2014). Systematic review of potential health risk posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminium, aluminum oxides, aluminum hydroxides and its soluble salts. Crit Rev Toxicol44(suppl 4): 1–88.Search in Google Scholar

Wills MR, Savory J. (1983). Aluminum poisoning: Dialysis encephalopathy, osteomalacia and anaemia. Lancet322: 29–34.Search in Google Scholar

Wills MR, Savory J. (1989). Aluminum and chronic renal failure: Sources, absorption, transport, and toxicity. Crit Rev Clin Lab Sci27: 59–107.Search in Google Scholar

Wisniewski HM, Sturman JA, Shek JW. (1980). Aluminum chloride induced neurofibrillary changes in the developing rabbit: a chronic animal model. Ann Neurol8: 479–490.Search in Google Scholar

Wisser LA, Heinrich BS, Leach RM. (1990). Effect of aluminum on performance and mineral metabolism in young chicks and laying hens. J Nutr120(5): 493–498.Search in Google Scholar

Woodson GC. (1998). An interesting case of osteomalacia due to antacid use associated with stainable bone aluminum in a patient with normal renal function. Bone22: 695–698.Search in Google Scholar

Xiea CX, Mattsonbc MP, Lovellcd MA, Yokelae RA. (1996). Intraneuronal aluminum potentiates iron-induced oxidative stress in cultured rat hippocampal neurons. Brain Res743(1–2): 271–277.Search in Google Scholar

Xu F, Liu Y, Zhao H, Yu K, Song M, Zhu Y, Li Y. (2017). Aluminum chloride caused liver dysfunction and mitochondrial energy metabolism disorder in rat. J Inorg Biochem174: 55–66.Search in Google Scholar

Xu F, Ren L, Song M, Shao B, Han Y, Cao Z, Li Y. (2018). Fas- and mitochondia-mediated signaling pathway involved in osteoblast apoptosis induced by AlCl3. Biol Trace Elem Res184(1): 173–185.Search in Google Scholar

Xu ZX, Fox L, Melethil S, Winberg L, Badr M. (1990). Mechanism of aluminum-induced inhibition of hepatic glycolysis: inactivation of phosphofructokinase. J Pharmacol Exp Ther254(1): 301–305.Search in Google Scholar

Xu Z-X, Zhang Q, Ma G-L, Chen C-H, He Y-M, Xu L-H, Zhang Y, Zhou G-R, Li Z-H, Yang H-J, Zhou P. (2016). Influence of aluinium and EGCCG on fibrillation and aggregation of human islet amyloid polypeptide. J Diabetes Res2016, ID 1867059, 14 pages. http://dx.org/10.1155/2016/1867059.Search in Google Scholar

Yahaya T, Obaroh I, Oladele EO. (2017). The roles of environmental pollutants in the pathogenesis and prevalence of diabetes: a review. J Appl Sci Environ Manag21: 5–8.Search in Google Scholar

Yamanaka K, Minato N, Iwai K. (1999). Stabilization of iron regulatory protein 2, IRP2, by aluminum. FEBS lett462: 216–220.Search in Google Scholar

Yang AM, ChengN, Pu HQ, Liu SM, Li JS, Bassig BA, Dai M, Li HY, Hu XB, Wei X, Zheng TZ, Bai YN. (2015). Metal exposure and risk of diabetes and pre-diabetes among Chinese occupational workers. Biomed Eviron Sci28(12): 875–883.Search in Google Scholar

Yang M, Jiang L, Huang H, Zeng S, Qiu F, Yu, Li X, Wei S. (2014). Dietary exposure to aluminium and health risk assessment in residents of Shenzhen, China. PLoS One9(3): e89715 https://doi.org/10.1371/journalpone.0089715.Search in Google Scholar

Yang S-J, Huh J-E, Lee JE, Choi SY, Kim TU, Cho S-W. (2003). Inactivation of human glutamate dehydrogenase by aluminum. Cell Mol Life Sci60(11): 2538–2546.Search in Google Scholar

Yang X, Huo H, Xiu C, Song M, Han Y, Li Y, Zhu Y. (2016). Inhibition of osteo-blast differentiation by aluminum trichloride exposure is associated with inhibition of BMP-2/Smad pathway component expression. Food Chem Toxicol97: 120–126.Search in Google Scholar

Yang X, Yu K, Wang H, Zhang H, Bai C, Song M, Han Y, Shao B, Li Y, Li X. (2018). Bone impairment caused AlCl3 is associated with activation of JNK apoptotic pathway mediated by oxidative stress. Food Chem Toxicol116(Part B): 307–314.Search in Google Scholar

Yassa HA, George SM, Mohamed HK. (2017). Folic acid improves developmental toxicity induced by aluminum sulphates. Environ Toxicol Pharmacol50: 32–36.Search in Google Scholar

Yokel RA. (2000). The toxicology of aluminum in the brain: a review. Neurotoxicology21: 813–828.Search in Google Scholar

Yokel RA. (2012). Aluminum in food-The nature and contributions of food additives. Food Additive (El-Samragy Y ed), ISBN: 978-953-51-0067-6, InTech, http://www.intechopen.com.Search in Google Scholar

Yokel RA, Florence RL. (2006). Aluminum bioavailability from the approved food additive leavening agent acidic sodium aluminum phosphate, incorporated into a baked good, is lower than from water. Toxicology227: 86–93.Search in Google Scholar

Yokel RA, Hicks CL, Florence RL. (2008). Aluminum bioavailability from basic sodium aluminum phosphate, an approved food additive emulsifying agent, incorporated in cheese. Food Chem Toxicol46: 2261–2266.Search in Google Scholar

Yokel RA, McNamara PJ. (2001). Aluminum toxicokinetics: an updated mini-review. Pharmacol Toxicol88: 159–167.Search in Google Scholar

Yousef MI, Kamel KL, ElGuendi MI, El-Demerdash FM. (2007). An in vitro study on reproductive toxicity of aluminium chloride on rabbit sperm: The protective role of some antioxidants. Toxicology239: 213–223.Search in Google Scholar

Yousef MI, Salama AF. (2009). Propolis protection from reproductive toxicity caused by aluminium chloride in male rats. Food Chem Toxicol47: 1168–1175.Search in Google Scholar

Yu H, Zhang J, Ji, Q, Wang P, Song M, Cao Z, Zhang X, Li Y. (2019). Melatonin alleviates aluminium chloride-induced immunotoxicity by inhibiting oxidative stress and apoptosis associated with the activation of Nrf2 signaling pathway. Ecotoxicol Environ Saf173: 131–141.Search in Google Scholar

Zatta P, Lain E, Cagnolini C. (2000). Effects of aluminum on activity of Krebs cycle enzymes and glutamate dehydrogenase in rat brain homogenate. Eur J Biochem267(10): 3049–3055.Search in Google Scholar

Zatta P, Perazzolo M, Corain B. (1989). Tris acetylacetonate aluminium (III) induces osmotic fragility and acanthocyte formation in suspended erythrocytes. Toxicol Lett45(1): 15–21.Search in Google Scholar

Zatta P, Ricchelli F, Drago D, Filipi B, Tognon G. (2005). Aluminum-triggered structural modification and aggregation of beta-amyloid. Cell Mol Life Sci62: 1725–1733.Search in Google Scholar

Zatta P, Zambenedetti P, Milanese M. (1999). Activation of monoamine oxidase type B by aluminum in rat brain homogenate. NeuroReport10(17): 3645–3648.Search in Google Scholar

Zhang F, Sun X, Yu H, Yang X, Song M, Han Y, Li Y, Zhu Y. (2017). Effects of aluminum trichloride on cartilage stimulatory growth factor in rats. Biometals30(1): 143–150.Search in Google Scholar

Zhang L, Lin X, Gu Q, Zhu Y, Zhao H, Li Y, Zhang Z. (2010). Effects of sub-chronic aluminum exposure on serum concentrations of iron and iron-associated proteins in rats. Biol Trace Elem Res141(1–3): 246–253.Search in Google Scholar

Zhang Q, Cao Z, Sun X, Zuang C, Huang W, Li Y. (2016). Aluminum trichloride induces hypertension and disturbs the function of erythrocyte membrane in male rats. Biol Trace Elem Res171(1): 116–123.Search in Google Scholar

Zhang Y, Song W. (2017). Islet amyloid polypeptide: another key molecule in Alzheimer’s pathogenesis? Prog Neurobiol153: 100–120.10.1016/j.pneurobio.2017.03.00128274676Search in Google Scholar

Zhou Y, Harris WR, Yokel RA. (2008). The influence of citrate, maltolate and fluoride on the gastrointestinal absorption of aluminum at a drinking water-relevant concentration: A 26Al and 14C study. J Inorg Biochem102: 798–808.Search in Google Scholar

Zhou Y, Yokel RA. (2005). The chemical species of aluminum influence its paracellular flux across and uptake into Caco-2 cells, a model of gastrointestinal absorption. Toxicol Sci87: 15–26.Search in Google Scholar

Zhu Y, Hu C, Zheng P, Miao L, Yan X, Li H, Wang Z, Gao B, Li Y. (2016a). Ginsenoside Rb1 alleviates aluminum chloride induced rat osteoblasts dysfunction. Toxicology368–369: 183–188.10.1016/j.tox.2016.07.01427470910Search in Google Scholar

Zhu Y, Li Y, Miao L, Wang Y, Liu Y, Yan X. (2014a). Immunotoxicity of aluminum. Chemosphere104: 1–6.10.1016/j.chemosphere.2013.10.05224287266Search in Google Scholar

Zhu Y, Xu F, Yan X, Miao L, Li H, Hu C, Wang Z, Lian S, Feng Z, Li Y. (2016b). The suppressive effects of aluminum chloride on osteoblasts function. Environ Toxicol Pharmacol48: 125–129.10.1016/j.etap.2016.10.00927771505Search in Google Scholar

Zhu YZ, Sun H, Fu Y, Wang J, Song M, Li M, Li YF, Miao LG. (2014b). Effects of sub-chronic aluminium chloride on spermatogenesis and testicular enzymatic activity in male rats. Life Sci102(1): 36–40.10.1016/j.lfs.2014.02.03524607783Search in Google Scholar

Zhuang C, Liu D, Yang X, Wang H, Han L, Li Y. (2016). The immunotoxicity of aluminum trichloride on rat peritoneal macrophages via β2-adrenoceptors/cAMP pathway acted by norepinephrine. Chemosphere149: 34–40.Search in Google Scholar

Zlatkovic J, Tsouchnikas G, Jarmer J, Koessi C, Stiasny K, Heinz FX. (2013). Aluminum hydroxide influences not only the extent but also the fine specificity and function activity of antibody responses to tick-borne encephalitis virus in mice. J Virol87(22): 12187–12195.Search in Google Scholar

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