Open Access

Lycopene supplementation prevents reactive oxygen species mediated apoptosis in Sertoli cells of adult albino rats exposed to polychlorinated biphenyls


Cite

Anway MD, Folmer J, Wright WW, Zirkin BR. (2003). Isolation of Sertoli cells from adult rat testes: an approach to ex vivo studies of Sertoli cell function. Biol Reprod. 68: 996-1002.Search in Google Scholar

Atessahin A, Karahan I, Turk G, Gur S, Yılmaz S, Ceribas AO. (2006a). Protective role of lycopene on cisplatin induced changes in sperm characteristics, testicular damage and oxidative stress in rats. Reprod Toxicol 21: 42-47.10.1016/j.reprotox.2005.05.003Search in Google Scholar

Atessahin A, Turk G, Karahan I, Yilmaz S, Ceribasi AO, Bulmus O. (2006b). Lycopene prevents adriamycin-induced testicular toxicity in rats. Fertil Steril85: 1216-1222.10.1016/j.fertnstert.2005.11.035Search in Google Scholar

Bhuvaneswari V and Nagini S. (2005.) Lycopene: a review of its potential as an anticancer agent. Curr. Med. Chem. Anticancer Agents 5: 627-635.10.2174/156801105774574667Search in Google Scholar

Carreau S, Foucault P, Drosdowsky MA. (1994). Sertoli cells: Functional aspects compared in rats, pigs and man. Ann Endocrinol 55: 203-220.Search in Google Scholar

Chinnaiyan AM, O’Rourke K, Tewari M, Dixit VM. (1995). FADD, a novel deathdomain- containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81: 505-512.Search in Google Scholar

Cohen LA. (2002). A review of animal model studies of tomato carotenoids, lycopene and cancer chemoprevention. Exp Biol Med 227: 864-868.Search in Google Scholar

de Winther MP, Kanters E, Kraal G, Hofker MH. (2005). Nuclear factor kappaB signaling in atherogenesis. Arterioscler Thromb Vasc Biol 25: 904-914.Search in Google Scholar

De Castro BR, Korrick SA, Spengler JD, Soto AM. (2006). Estrogenic activity of polychlorinated biphenyls present in human tissue and the environment. Environ Sci Technol 40: 2819-2825.Search in Google Scholar

Devasagayam TP and Tarachand U. (1987). Decreased lipid peroxidation in rat kidneys during gestation. Biochem Biophys Res Comm 145: 134-138.Search in Google Scholar

Dubois W, Callard GV. (1990). Shark testis model: stage-dependent functions and the regulation of spermatogenesis. J Exp Zool 4: 142-144.Search in Google Scholar

Eldadah BA, Faden AI. (2000). Caspase pathways, neuronal apoptosis and CNS injury. J Neurotrauma 17: 811-829.Search in Google Scholar

Elumalai P, Krishnamoorthy G, Selvakumar K, Arunkumar R, Venkataraman P, Arunakaran J. (2009). Studies on the protective role of lycopene against polychlorinated biphenyls (Aroclor 1254)-induced changes in StAR protein and cytochrome P450 scc enzyme expression on Leydig cells of adult rats. Reprod Toxicol 27: 41-45.Search in Google Scholar

Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. (1998). A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1: 43-50.Search in Google Scholar

Green DR, Reed JC. (1998). Mitochondria and apoptosis. Science 281: 1309-1312.Search in Google Scholar

Griffith HR, Unswoth J, Blake DR, Lunec J. (1988). Oxidation of amino acidswithin serum proteins. In: Rice-Evans (Ed.), Free radicals: Chemistry, Pathology and Medicine Richeliue, London, pp.439-454.Search in Google Scholar

Hengartner MO. (1999). Programmed cell death in the nematode C. elegans. Recent Prog Horm Res 54: 213-222.Search in Google Scholar

Griswold MD. (1993). The central role of Sertoli cells in spermatogenesis. Seminarsin Cell & Develop Biol 9: 411-416.Search in Google Scholar

Hochstein P, Ernster L. (1963.) ADP-activated lipid peroxidation coupled on TPNH oxidase system of microsomes. Biochem Biophys Res Comm 12: 388-394.10.1016/0006-291X(63)90111-6Search in Google Scholar

Kasai H, Crain PF, Kuchino, Y, Nishimura S, Ootsyama A, Tanoaka H. (1986). Formation of 8-hydroxy-guanine moiety in cellular DNA by agents producing oxygen radical and evidence for its repair. Carcinogenesis 7: 1849-1851.Search in Google Scholar

Khan SM, Oliver RH, Dauffenbach LM, Yeh J. (2000). Depletion of Raf-1 protooncogene by geldanamycin causes apoptosis in human luteinized granulosa cells. Fertil Steril 74: 359-365.Search in Google Scholar

Kothakota S, Azuma T, Reinhard C, Klippel A, Tang J, Chu K, McGarry TJ, Kirschner MW, Koths K, Kwiatkowski DJ, Williams LT. (1997). Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science 278: 294-298.Search in Google Scholar

Krishnamoorthy G, Venkataraman P, Arunkumar A, Vignesh RC, Aruldhas MM, Arunakaran J. (2007). Ameliorative effect of vitamins (alpha-tocopherol and ascorbic acid) on PCB (Aroclor 1254) induced oxidative stress in rat epididymal sperm. Reprod Toxicol 23: 239-245.Search in Google Scholar

Krishnamoorthy G, Selvakumar K, Elumalai P, Venkataraman P, Arunakaran J. (2011). Protective role of lycopene on polychlorinated biphenyls (Aroclor 1254)-induced adult rat Sertoli cell dysfunction by increased oxidative stress and endocrine disruption. Biomed Prev Nutr 1: 116-125.Search in Google Scholar

Krishnamoorthy G, Murugesan P, Muthuvel R, Gunadharini DN, Vijayababu MR, Arunkumar A, Venkataraman P, Aruldhas MM, Arunakaran J. (2005). Effect of Aroclor 1254 on Sertoli cellular antioxidant system, androgen binding protein and lactate in adult rat in vitro. Toxicology 212: 195-205.Search in Google Scholar

Martin SJ, O’Brien GA, Nishioka WK, McGahon AJ, Mahboubi A, Saido TC, Green DR. (1995). Proteolysis of fodrin (non-erythroid spectrin) during apoptosis. J Biol Chem 270: 6425-6428.Search in Google Scholar

McLean MR., Bauer U, Amaro AR, Robertson LW. (1996). Identification of catechol and hydroquinone metabolites of 4-monochlorobiphenyl. Chem ResToxicol 9: 158-164.Search in Google Scholar

Murugesan P, Balaganesh M, Balasubramanian K, Arunakaran J. (2007a). Effects of polychlorinated biphenyl (Aroclor 1254) on steroidogenesis and antioxidant system in cultured adult rat Leydig cells. J Endocrinol 192: 325-338.10.1677/joe.1.0687417283232Search in Google Scholar

Murugesan P, Senthilkumar J, Balasubramanian K, Aruldhas MM, Arunakaran J. (2005a). Impact of polychlorinated biphenyl Aroclor 1254 on testicular antioxidant system in adult rats. Hum Exp Toxicol 24: 61-66.10.1191/0960327105ht500oa15850280Search in Google Scholar

Murugesan P, Muthusamy T, Balasubramanian K, Arunakaran J. (2005b). Studies on the protective role of vitamin C and E against polychlorinated biphenyl (Aroclor 1254)-induced oxidative damage in Leydig cells. Free Rad Res39: 1259-1272.10.1080/1071576050030815416298753Search in Google Scholar

Nehar D, Mauduit C, Boussouar F, Benahmed M. (1998). Interleukin 1a Stimulates Lactate Dehydrogenase A Expression and Lactate production in cultured porcine Sertoli cells. Biol Reprod 59: 1425-1432.Search in Google Scholar

Orrenius S, McCabe MJ Jr, Nicotera P. (1992). Ca(2+)-dependent mechanisms of cytotoxicity and programmed cell death. Toxicol Lett 64-65 Spec No: 357-64.Search in Google Scholar

Orth JM, Gunsalus GL, Lamperti AA. (1988). Evidence from Sertoli cell-depleted rats indicates that spermatid number in adults depends on numbers of Sertoli cells produced during perinatal development. Endocrinology122: 787-794.Search in Google Scholar

Pick E, Keisari Y. (1981). Superoxide anion and hydrogen peroxide production by chemically elicited peritoneal macrophages-induction by multiple nonphagocytic stimuli. Cell Immunol 59: 301-318.Search in Google Scholar

Porrini M, Riso P. (2000). Lymphocyte lycopene concentration and DNA protection from oxidative damage is increased in women after a short period of tomato consumption. J Nutr 130: 189-192.Search in Google Scholar

Puntarulo S, Cederbaum AI. (1988). Effect of oxygen concentration on microsomal oxidation of ethanol and generation of oxygen radicals. Biochem J251: 787-794.Search in Google Scholar

Rao AV, Agarwal S. (2000). Role of antioxidant lycopene in cancer and heart disease. J Am Coll Nutr 19: 563-569.Search in Google Scholar

Ratnasoorya WD. (1984). Effect of atropine on fertility of female rat and sperm motility. Indian J Exp Biol 22: 463-470.Search in Google Scholar

Rudel T, Bokoch GM. (1997). Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 6: 1571-1574.Search in Google Scholar

Schlezinger JJ, Keller J, Verbrugge LA, Stegeman JJ. (2000). 3,3’,4,4’-Tetrachlorobiphenyl oxidation in fish, bird and reptile species: relationship to cytochrome P450 1A inactivation and reactive oxygen production. Comp. Biochem. Physiol C Toxicol Pharmacol 125: 273-286.Search in Google Scholar

Seligman J, Shalgi K, Oschry Y, Kosower NS. (1991). Sperm analysis by flow cytometry using the fluorescent thiol labeling agent monobromobimane. Mol Reprod Dev 29: 276-281.Search in Google Scholar

Senthilkumar J, Banudevi S, Sharmila M, Murugesan P, Srinivasan N, Balasubramanian K, Aruldhas MM, Arunakaran J. (2004). Effects of vitamin C and E on PCB (Aroclor 1254) induced oxidative stress, androgen binding protein and lactate in rat Sertoli cells. Reprod Toxicol 9: 201-208.Search in Google Scholar

Shi Y, Song Y, Wang Y, Wang Y, Liang Y, Hu Y, Yu H, Guan X, Cheng J, Yang K. (2009). β-Benzene hexachloride induces apoptosis of rat Sertoli cells through generation of reactive oxygen species and activation of JNKs and FasL. Environ Toxicol 26: 124-135.Search in Google Scholar

Shimizu K, Ogawa F, Thiele JJ, Bae S, Sato S. (2007). Lipid peroxidation is enhanced in Yusho victims 35 years after accidental poisoning with polychlorinated biphenyls in Nagasaki, Japan. J Appl Toxicol 27: 195-197.Search in Google Scholar

Scolastici C, Lopes GA, Barbisan LF, Salvadori DM. (2008). Tomato oleoresin inhibits DNA damage but not diethylnitrosamine-induced rat hepatocarcinogenesis. Exp Toxicol Pathol 60: 59-68.Search in Google Scholar

Scolastici C, Alves de Lima RO, Barbisan LF, Ferreira AL, Ribeiro DA, Salvadori DM. (2008). Antigenotoxicity and antimutagenicity of lycopene in HepG2 cell line evaluated by the comet assay and micronucleus test. Toxicol In vitro22: 510-514.Search in Google Scholar

Song Y, Yang KD. (2006). Effect of p, p’-DDE on DNA damage and expression of FasL gene of rat Sertoli cell in vitro. Wei Sheng Yan Jiu 35: 261-263.Search in Google Scholar

Steinberger A , Klinefelter GR. (1993). Sensitivity of Sertoli and Leydig cells to xenobiotics in in vitro models. Reprod Toxicol 7: 23-57.Search in Google Scholar

Steinberger A, Steinberger E. (1971). Replication pattern of Sertoli cells in maturing rat testis in vivo and in organ culture. Biol Reprod 4: 84-87.Search in Google Scholar

Syed V, Gu W, Hecht N. (1997). Sertoli cells in culture and mRNA differential display provide a sensitive early warning assay system to detect changes induced by xenobiotics. J Androl 18: 264-273.Search in Google Scholar

Tang L, Guan H, Ding X, Jia-Sheng W. (2007). Modulation of aflatoxin toxicity and biomarkers by lycopene in F344 rats. Toxicol Appl Pharmacol 219: 10-17.Search in Google Scholar

Tapiero H, Townsend DM, Tew KD. (2004). The role of carotenoids in the prevention of human pathologies. Biomed Pharmacother 58: 100-110.Search in Google Scholar

Turk G, Atessahin A, Sonmez M, Yuce A, Ceribas AO. (2007). Lycopene protects against cyclosporine A-induced testicular toxicity in rats. Theriogenology67: 778-785.Search in Google Scholar

Twaroski TP, O’Brien ML, Larmonier N, Glauert HP, Rorbertson LW. (2001). Polychlorinated biphenyls-induced effects of metabolic enzymes, AP-1 binding, vitamin E, and oxidative stress in the rat liver. Toxicol Appl Pharmacol171: 85-93.Search in Google Scholar

Venkataraman P, Selvakumar K, Krishnamoorthy G, Muthusami S, Rameshkumar R, Prakash S, Arunakaran J. (2010). Effect of melatonin on PCB (Aroclor 1254) induced neuronal damage and changes in Cu/Zn superoxide dismutase and glutathione peroxidase-4 mRNA expression in cerebral cortex, cerebellum and hippocampus of adult rats. Neurosci Res 66: 189-197.Search in Google Scholar

Venkataraman P, Krishnamoorthy G, Vengatesh G, Srinivasan N, Aruldhas MM, Arunakaran J. (2008). Protective role of melatonin on PCB (Aroclor 1,254) induced oxidative stress and changes in acetylcholine esterase and membrane bound ATPases in cerebellum, cerebral cortex and hippocampus of adult rat brain. Int J Dev Neurosci 26: 585-591.Search in Google Scholar

Wang X. (2001). The expanding role of mitochondria in apoptosis. Genes Dev15: 2922-2933.Search in Google Scholar

Yagi M, Suzuki K, Suzuki H. (2006). Apoptotic Sertoli cell death in hypogonadic (hgn/hgn) rat testes during early postnatal development. Asian J Androl8: 535-541.Search in Google Scholar

Yilmaz S, Atessahin A, Sahna E, Karahan I, Ozer S. (2006). Protective effect of lycopene on adriamycin-induced cardiotoxicity and nephrotoxicity. Toxicology218: 164-171. Search in Google Scholar

eISSN:
1337-9569
ISSN:
1337-6853
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Medicine, Clinical Medicine, Pharmacology, Toxicology