The Impact of Technical Skills and Education on Exacerbations, Adherence to Treatment and the Choice of Inhaler Device in Patients with COPD

1 Anderson, P. (2005). Patient preference for and satisfaction with inhaler devices. European Respiratory Review, 14(96), 109–116. https://doi.org/10.1183/09059180.05.00009606 Search in Google Scholar

2 Bonini, M., & Usmani, O. S. (2015). The importance of inhaler devices in the treatment of COPD. COPD Research and Practice, 1(1), 9. https://doi.org/10.1186/s40749-015-0011-0 Search in Google Scholar

3 Calzetta, L., Aiello, M., Frizzelli, A., Ritondo, B. L., Pistocchini, E., Rogliani, P., & Chetta, A. (2022). Impact of Sex on Proper Use of Inhaler Devices in Asthma and COPD: A Systematic Review and Meta-Analysis. Pharmaceutics, 14(8). https://doi.org/10.3390/pharmaceutics14081565 Search in Google Scholar

4 Cazzola, M., & Matera, M. G. (2012). IL-17 in chronic obstructive pulmonary disease. Expert Review of Respiratory Medicine, 6(2), 135–138. https://doi.org/10.1586/ers.12.7 Search in Google Scholar

5 Cecere, L. M., Slatore, C. G., Uman, J. E., Evans, L. E., Udris, E. M., Bryson, C. L., & Au, D. H. (2012). Adherence to Long-Acting Inhaled Therapies among Patients with Chronic Obstructive Pulmonary Disease (COPD). COPD: Journal of Chronic Obstructive Pulmonary Disease, 9(3), 251–258.https://doi.org/10.3109/15412555.2011.650241 Search in Google Scholar

6 Cerveri, I., Locatelli, F., Zoia, M. C., Corsico, A., Accordini, S., & de Marco, R. (1999). International variations in asthma treatment compliance: the results of the European Community Respiratory Health Survey (ECRHS). European Respiratory Journal, 14(2), 288 LP – 294. http://erj.ersjournals.com/content/14/2/288.abstract Search in Google Scholar

7 Chrystyn, H., van der Palen, J., Sharma, R., Barnes, N., Delafont, B., Mahajan, A., & Thomas, M. (2017). Device errors in asthma and COPD: systematic literature review and meta-analysis. Npj Primary Care Respiratory Medicine, 27(1), 22. https://doi.org/10.1038/s41533-017-0016-z Search in Google Scholar

8 Dantic, D. E. (2014). A critical review of the effectiveness of “teach-back” technique in teaching COPD patients self-management using respiratory inhalers. Health Education Journal, 73(1), 41–50. https://doi.org/10.1177/0017896912469575 Search in Google Scholar

9 Darbà, J., Ramírez, G., Sicras, A., Francoli, P., Torvinen, S., & Sánchez-De La Rosa, R. (2015). The importance of inhaler devices: The choice of inhaler device may lead to suboptimal adherence in COPD patients. International Journal of COPD, 10(1), 2335–2345. https://doi.org/10.2147/COPD.S90155 Search in Google Scholar

10 Davis, J. R., Wu, B., Kern, D. M., Tunceli, O., Fox, K. M., Horton, J., Legg, R. F., & Trudo, F. (2017). Impact of Nonadherence to Inhaled Corticosteroid/LABA Therapy on COPD Exacerbation Rates and Healthcare Costs in a Commercially Insured US Population. American Health & Drug Benefits, 10(2), 92–102. Search in Google Scholar

11 Disease, G. initiative for strategy for chronic obstructive lung. (2018). Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: 2018 Report. In GOLD, Global Obstructive Lung Disease. https://goldcopd.org/wp-content/uploads/2017/11/GOLD-2018-v6.0-FINAL-revised-20-Nov_WMS.pdf Search in Google Scholar

12 Duarte-de-Araújo, A., Teixeira, P., Hespanhol, V., & Correia-de-Sousa, J. (2019). COPD: misuse of inhaler devices in clinical practice. International Journal of Chronic Obstructive Pulmonary Disease, 14, 1209–1217. https://doi.org/10.2147/COPD.S178040 Search in Google Scholar

13 Lareau, S. C., & Yawn, B. P. (2010). Improving adherence with inhaler therapy in COPD. International Journal of Chronic Obstructive Pulmonary Disease, 5, 401–406. https://doi.org/10.2147/copd.s14715 Search in Google Scholar

14 Lavorini, F., & Fontana, G. A. (2014). Inhaler technique and patient’s preference for dry powder inhaler devices. Expert Opinion on Drug Delivery, 11(1), 1–3. https://doi.org/10.1517/17425247.2014.846907 Search in Google Scholar

15 Lavorini, F., Magnan, A., Christophe Dubus, J., Voshaar, T., Corbetta, L., Broeders, M., Dekhuijzen, R., Sanchis, J., Viejo, J. L., Barnes, P., Corrigan, C., Levy, M., & Crompton, G. K. (2008). Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD. Respiratory Medicine, 102(4), 593–604. https://doi.org/https://doi.org/10.1016/j.rmed.2007.11.003 Search in Google Scholar

16 Luiza, M., Souza, M., Meneghini, A. C., Ferraz, É., Oliveira Vianna, E., & Carvalho Borges, M. (2009). Knowledge of and technique for using inhalation devices among asthma patients and COPD patients* Técnica e compreensão do uso dos dispositivos inalatórios em pacientes com asma ou DPOC Knowledge of and technique for using inhalation devices among asthma p. J Bras Pneumol, 35(9), 824–831. Search in Google Scholar

17 Mäkelä, M. J., Backer, V., Hedegaard, M., & Larsson, K. (2013). Adherence to inhaled therapies, health outcomes and costs in patients with asthma and COPD. Respiratory Medicine, 107(10), 1481–1490. https://doi.org/https://doi.org/10.1016/j.rmed.2013.04.005 Search in Google Scholar

18 Meek, P. M., Lareau, S. C., & Fahy, B. F. (2006). Selection of aerosol delivery device. International Journal of Respiratory Care, 2(4), 130–133. Search in Google Scholar

19 Melani, A. S., Bonavia, M., Cilenti, V., Cinti, C., Lodi, M., Martucci, P., Serra, M., Scichilone, N., Sestini, P., Aliani, M., & Neri, M. (2011). Inhaler mishandling remains common in real life and is associated with reduced disease control. Respiratory Medicine, 105(6), 930–938. https://doi.org/https://doi.org/10.1016/j.rmed.2011.01.005 Search in Google Scholar

20 Miravitlles, M., Soler-Cataluña, J. J., Alcázar, B., Viejo, J. L., & García-Río, F. (2018). Factors affecting the selection of an inhaler device for COPD and the ideal device for different patient profiles. Results of EPOCA Delphi consensus. Pulmonary Pharmacology and Therapeutics, 48, 97–103. https://doi.org/10.1016/j.pupt.2017.10.006 Search in Google Scholar

21 Molimard, M., & Colthorpe, P. (2015). Inhaler devices for chronic obstructive pulmonary disease: Insights from patients and healthcare practitioners. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 28(3), 219–228. https://doi.org/10.1089/jamp.2014.1142 Search in Google Scholar

22 Navaie, M., Dembek, C., Cho-Reyes, S., Yeh, K., & Celli, B. R. (2020). Device use errors with soft mist inhalers: A global systematic literature review and meta-analysis. Chronic Respiratory Disease, 17, 1479973119901234. https://doi.org/10.1177/1479973119901234 Search in Google Scholar

23 Ocakli, B., Ozmen, I., Tuncay, E. A., Gungor, S., Ozalp, A., Yasin, Y., Adiguzel, N., Gungor, G., & Karakurt, Z. (2020). Influence of gender on inhaler technique. Respiratory Care, 65(10), 1470–1477. https://doi.org/10.4187/respcare.06917 Search in Google Scholar

24 Price, D., Keininger, D. L., Viswanad, B., Gasser, M., Walda, S., & Gutzwiller, F. S. (2018). Factors associated with appropriate inhaler use in patients with COPD -lessons from the REAL survey. International Journal of Chronic Obstructive Pulmonary Disease, 13, 695–702. https://doi.org/10.2147/COPD.S149404 Search in Google Scholar

25 Restrepo, R. D., Alvarez, M. T., Wittnebel, L. D., Sorenson, H., Wettstein, R., Vines, D. L., Sikkema-Ortiz, J., Gardner, D. D., & Wilkins, R. L. (2008). Medication adherence issues in patients treated for COPD. International Journal of COPD, 3(3), 371–384. https://doi.org/10.2147/copd.s3036 Search in Google Scholar

26 Scichilone, N., Benfante, A., Bocchino, M., Braido, F., Paggiaro, P., Papi, A., Santus, P., & Sanduzzi, A. (2015). Which factors affect the choice of the inhaler in chronic obstructive respiratory diseases? Pulmonary Pharmacology and Therapeutics, 31, 63–67. https://doi.org/10.1016/j.pupt.2015.02.006 Search in Google Scholar

27 Takemura, M., Mitsui, K., Itotani, R., Ishitoko, M., Suzuki, S., Matsumoto, M., Aihara, K., Oguma, T., Ueda, T., Kagioka, H., & Fukui, M. (2011). Relationships between repeated instruction on inhalation therapy, medication adherence, and health status in chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease, 6, 97–104. https://doi.org/10.2147/COPD.S16173 Search in Google Scholar

28 Virchow, J. C., Crompton, G. K., Dal Negro, R., Pedersen, S., Magnan, A., Seidenberg, J., & Barnes, P. J. (2008). Importance of inhaler devices in the management of airway disease. Respiratory Medicine, 102(1), 10–19. https://doi.org/https://doi.org/10.1016/j.rmed.2007.07.031 Search in Google Scholar

29 Yawn, B. P., Colice, G. L., & Hodder, R. (2012). Practical aspects of inhaler use in the management of chronic obstructive pulmonary disease in the primary care setting. International Journal of COPD, 7, 495–502. https://doi.org/10.2147/COPD.S32674 Search in Google Scholar