<abstract xmlns="http://www.w3.org/1999/xhtml">

<bold>Introduction.</bold> Because of the increasing interest in the study of saliva, many methods have become available that can allow us to perform multiple and rapid analyzes of the composition of salivary secretion using advanced techniques of nanotechnology and fluid micro- engineering. The objectives of our study were to identify immunoglobulin levels variations with age.
<bold>Materials and methods.</bold> We conducted an analysis to check the correlation between saliva and plasma parameters on 24 patients. The study population was divided into 2 groups based on age, with a cut-off at 35 years. The differences on the variables between two groups were evaluated by TTEST and CORREL.
<bold>Results.</bold> Total plasma calcium, as well as ionic calcium have increased values in group 2, the increase being statistically significant (p =0.04) only for ionic calcium. Significant correlation of plasma and salivary values in the case of IgA / IgG ratio, and also a significant correlation of salivary and plasma concentrations for IgG were identified in our study.
<bold>Conclusions.</bold> The correlation between plasma and salivary parameters is closely related to age and these can be used as markers for diagnosis and evaluation of various pathologies. Also, regarding women, salivary calcium and phosphate concentrations increase with age showing peak values around menopause.
</abstract>

Introduction. Because of the increasing interest in the study of saliva, many methods have become available that can allow us to perform multiple and rapid analyzes of the composition of salivary secretion using advanced techniques of nanotechnology and fluid micro- engineering. The objectives of our study were to identify immunoglobulin levels variations with age.
Materials and methods. We conducted an analysis to check the correlation between saliva and plasma parameters on 24 patients. The study population was divided into 2 groups based on age, with a cut-off at 35 years. The differences on the variables between two groups were evaluated by TTEST and CORREL.
Results. Total plasma calcium, as well as ionic calcium have increased values in group 2, the increase being statistically significant (p =0.04) only for ionic calcium. Significant correlation of plasma and salivary values in the case of IgA / IgG ratio, and also a significant correlation of salivary and plasma concentrations for IgG were identified in our study.
Conclusions. The correlation between plasma and salivary parameters is closely related to age and these can be used as markers for diagnosis and evaluation of various pathologies. Also, regarding women, salivary calcium and phosphate concentrations increase with age showing peak values around menopause.

Correlation Depending on Age Between Saliva and Plasma Parameters

“Carol Davila” University of Medicine and Pharmacy

Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Correlation Depending on Age Between Saliva and Plasma Parameters"}

Introduction. Because of the increasing interest in the study of saliva, many methods have become available that can allow us to perform multiple and rapid...

Correlation Depending on Age Between Saliva and Plasma Parameters

Published Online: Jan 14, 2023

Page range: 27 - 35

DOI: https://doi.org/10.2478/inmed-2022-0226

Keywords
saliva, plasma, immunoglobulin, age

© 2022 Daniela-Gabriela Bălan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Correlation Depending on Age Between Saliva and Plasma Parameters

Published Online: Jan 14, 2023

Page range: 27 - 35

DOI: https://doi.org/10.2478/inmed-2022-0226

Keywordssaliva, plasma, immunoglobulin, age

© 2022 Daniela-Gabriela Bălan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
saliva, plasma, immunoglobulin, age