<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Congenital aortic bicuspid valve can evolve rapidly and at an early age to a severe aortic disease with significant stenosis and regurgitation. Therefore, cardiovascular surgery with mechanical aortic prosthesis implant is the only therapeutic solution. Despite a successful surgical procedure, complications can be numerous, especially post-operatively, as conduction disorders and arrhythmias. Also, given the recent guidelines recommendations to maintain the INR values above 2,5, chronic oral anticoagulation is critical in the long-term prevention of cardioembolic events. Thus, we are presenting the case of a patient diagnosed with a severe aortic disease secondary to a bicuspid aortic valve, who underwent a Bentall surgical procedure, later suffering a wide spectrum of complications, both immediate and late, especially due to long-term subtherapeutic INR values. The particularities of the case reside both in the multitude of complications that occurred in a particular chronological order and in the interfering mechanisms with the anticoagulant therapy.</p>
</abstract>

Congenital aortic bicuspid valve can evolve rapidly and at an early age to a severe aortic disease with significant stenosis and regurgitation. Therefore, cardiovascular surgery with mechanical aortic prosthesis implant is the only therapeutic solution. Despite a successful surgical procedure, complications can be numerous, especially post-operatively, as conduction disorders and arrhythmias. Also, given the recent guidelines recommendations to maintain the INR values above 2,5, chronic oral anticoagulation is critical in the long-term prevention of cardioembolic events. Thus, we are presenting the case of a patient diagnosed with a severe aortic disease secondary to a bicuspid aortic valve, who underwent a Bentall surgical procedure, later suffering a wide spectrum of complications, both immediate and late, especially due to long-term subtherapeutic INR values. The particularities of the case reside both in the multitude of complications that occurred in a particular chronological order and in the interfering mechanisms with the anticoagulant therapy.

Immediate and Late Complications in Aortic Valve Replacement Surgery

“Grigore T. Popa” University of Medicine and Pharmacy

Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Immediate and Late Complications in Aortic Valve Replacement Surgery"}

Congenital aortic bicuspid valve can evolve rapidly and at an early age to a severe aortic disease with significant stenosis and regurgitation. Therefore,...

Immediate and Late Complications in Aortic Valve Replacement Surgery

Published Online: Oct 15, 2022

Page range: 75 - 81

DOI: https://doi.org/10.2478/inmed-2022-0222

Keywords
bicuspid aortic valve, mechanical aortic prosthesis, chronic oral anticoagulation

© 2022 Alexandru-Dan Costache et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Immediate and Late Complications in Aortic Valve Replacement Surgery

Published Online: Oct 15, 2022

Page range: 75 - 81

DOI: https://doi.org/10.2478/inmed-2022-0222

Keywordsbicuspid aortic valve, mechanical aortic prosthesis, chronic oral anticoagulation

© 2022 Alexandru-Dan Costache et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
bicuspid aortic valve, mechanical aortic prosthesis, chronic oral anticoagulation