<abstract xmlns="http://www.w3.org/1999/xhtml">

<bold>Introduction.</bold> Post-cholecystectomy cholangitis represents a controversial issue within the medical literature due to the polymorphism of the generating causes and due to the difficulties connected to its diagnosis and therapy.
<bold>Material and methods.</bold> The assessment of the study was performed on two batches of patients, namely 221 patients hospitalized at Surgery Departments and another batch of 109 patients hospitalized at the Gastroenterology Department all having post-cholecystectomy cholangitis as their main diagnosis. The assessment criteria were suggestive laboratory and imagery investigations and therapeutic management.
<bold>Results.</bold> If we compare the laboratory profile of both batches, we can see that only the non-specific inflammatory syndrome has shown significant differences statistically (way more frequent in case of patients hospitalized at the Gastroenterology Department), while the biliary-excretion, the cholestatic and hepatic cytolysis syndromes had approximately the same prevalence. In both batches, the treatment methods used were mainly pharmacology methods, and in a small number of cases retrograde endoscopic cholangiopancreatography. There were also a few cases where invasive surgery was applied.
<bold>Conclusion.</bold> An increased clinical suspicion, an early recognition based on laboratory and imagery investigations, a prompt therapy initiation, and a balanced and correct anti-microbial management, endoscopic and surgical, need the implication of complex teams of clinicians.
</abstract>

Introduction. Post-cholecystectomy cholangitis represents a controversial issue within the medical literature due to the polymorphism of the generating causes and due to the difficulties connected to its diagnosis and therapy.
Material and methods. The assessment of the study was performed on two batches of patients, namely 221 patients hospitalized at Surgery Departments and another batch of 109 patients hospitalized at the Gastroenterology Department all having post-cholecystectomy cholangitis as their main diagnosis. The assessment criteria were suggestive laboratory and imagery investigations and therapeutic management.
Results. If we compare the laboratory profile of both batches, we can see that only the non-specific inflammatory syndrome has shown significant differences statistically (way more frequent in case of patients hospitalized at the Gastroenterology Department), while the biliary-excretion, the cholestatic and hepatic cytolysis syndromes had approximately the same prevalence. In both batches, the treatment methods used were mainly pharmacology methods, and in a small number of cases retrograde endoscopic cholangiopancreatography. There were also a few cases where invasive surgery was applied.
Conclusion. An increased clinical suspicion, an early recognition based on laboratory and imagery investigations, a prompt therapy initiation, and a balanced and correct anti-microbial management, endoscopic and surgical, need the implication of complex teams of clinicians.

Comparative Study of the Laboratory, Imagery and Therapeutic Profile of Patients Hospitalized at the Gastroenterology Versus Surgery Department Diagnosed with Cholangitis after Cholecystectomy

Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Introduction. Post-cholecystectomy cholangitis represents a controversial issue within the medical literature due to the polymorphism of the generating causes...

Comparative Study of the Laboratory, Imagery and Therapeutic Profile of Patients Hospitalized at the Gastroenterology Versus Surgery Department Diagnosed with Cholangitis after Cholecystectomy

Published Online: Apr 10, 2022

Page range: 7 - 17

DOI: https://doi.org/10.2478/inmed-2022-0194

Keywords
cholangitis, choledochal lithiasis, endoscopic retrograde cholangiopancreatography

© 2022 Mariana Ungur, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Comparative Study of the Laboratory, Imagery and Therapeutic Profile of Patients Hospitalized at the Gastroenterology Versus Surgery Department Diagnosed with Cholangitis after Cholecystectomy

Published Online: Apr 10, 2022

Page range: 7 - 17

DOI: https://doi.org/10.2478/inmed-2022-0194

Keywordscholangitis, choledochal lithiasis, endoscopic retrograde cholangiopancreatography

© 2022 Mariana Ungur, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
cholangitis, choledochal lithiasis, endoscopic retrograde cholangiopancreatography