<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Cushing’s syndrome (CS) is a clinical condition resulting from chronic exposure to glucocorticoid excess. Hypercortisolism contributes significantly to the early development of systemic disorders by direct and/or indirect effects. Complications such as obesity, hypertension, diabetes, dyslipidemia, and hypercoagulability cause premature atherosclerosis and increase cardiovascular mortality. These associated abnormalities increase cardiovascular risk not only during the active phase of the disease but also long after the remission of hypercortisolism. Clinical management of these patients should be particularly careful and control of cardiovascular risk factors is necessary for a long period.</p></abstract>

Cushing’s syndrome (CS) is a clinical condition resulting from chronic exposure to glucocorticoid excess. Hypercortisolism contributes significantly to the early development of systemic disorders by direct and/or indirect effects. Complications such as obesity, hypertension, diabetes, dyslipidemia, and hypercoagulability cause premature atherosclerosis and increase cardiovascular mortality. These associated abnormalities increase cardiovascular risk not only during the active phase of the disease but also long after the remission of hypercortisolism. Clinical management of these patients should be particularly careful and control of cardiovascular risk factors is necessary for a long period.

The Cardiovascular Risk in Cushing’s Syndrome

“C.I. Parhon” National Institute of Endocrinology

“Carol Davila” University of Medicine and Pharmacy

Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"The Cardiovascular Risk in Cushing\u2019s Syndrome"}

Cushing’s syndrome (CS) is a clinical condition resulting from chronic exposure to glucocorticoid excess. Hypercortisolism contributes significantly to the...

The Cardiovascular Risk in Cushing’s Syndrome

Published Online: Jul 18, 2019

Page range: 35 - 45

DOI: https://doi.org/10.2478/inmed-2019-0058

Keywords
Cushing’s syndrome, hypercortisolism, obesity, hypertension, diabetes, dyslipidemia, hypercoagulability, atherosclerosis, cardiovascular risk

© 2019 Mariana Dobrescu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Cardiovascular Risk in Cushing’s Syndrome

Published Online: Jul 18, 2019

Page range: 35 - 45

DOI: https://doi.org/10.2478/inmed-2019-0058

KeywordsCushing’s syndrome, hypercortisolism, obesity, hypertension, diabetes, dyslipidemia, hypercoagulability, atherosclerosis, cardiovascular risk

© 2019 Mariana Dobrescu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Cushing’s syndrome, hypercortisolism, obesity, hypertension, diabetes, dyslipidemia, hypercoagulability, atherosclerosis, cardiovascular risk