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Effectiveness of family psychosocial intervention on mental health and family function of caregivers of children with cancer: a meta-analysis


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Figure 1.

PRISMA flow diagram for the study selection process.
PRISMA flow diagram for the study selection process.

Figure 2.

Risk of bias summary: assessment of each risk bias item for the individual studies.
Risk of bias summary: assessment of each risk bias item for the individual studies.

Figure 3.

Forest plot: effect of family psychosocial intervention on caregiver anxiety level.
Forest plot: effect of family psychosocial intervention on caregiver anxiety level.

Figure 4.

Forest plot: effect of family psychosocial intervention on caregiver depression level.
Forest plot: effect of family psychosocial intervention on caregiver depression level.

Figure 5.

Forest plot: subgroup analysis of the effects of family psychosocial intervention on caregiver PTSD symptoms.
Forest plot: subgroup analysis of the effects of family psychosocial intervention on caregiver PTSD symptoms.

Figure 6.

Forest plot: effect of family psychosocial intervention on family function.
Forest plot: effect of family psychosocial intervention on family function.

Publication bias.

ltems Egger’s test Begg’s test
Z value P Z value P
Anxiety −0.01 0.9886 −0.12 1.0000
Depression 0.68 0.4973 −0.34 1.0000
PTSD 0.75 0.4539 0.24 0.8065
Family function 0.21 0.8370

Characteristics of the included RCT studies.

Study/country Cancer type Sample size Intervention type Duration of intervention No. of sections Section length Frequency of intervention Follow-up Measurement tools Outcome indicators
Experimental group Control group
Liu et al,14/ China Unlimited 30 28 Family task intervention 4 weeks 8 45 Twice a week Immediately after intervention FFFS
Fu et al.9/ China Hematological tumors 20 20 Structural family therapy 8 weeks 4 60 Every 2 weeks 1 month after intervention FAD
Hoekstra-Weebers et al,15/ Netherlands Unlimited 20 21 Family cognitive behavior intervention 21 weeks 7 90 Every 3 weeks 6 months after intervention STAI
Kazak et al.16/ USA Unlimited 129 115 Family cognitive behavior intervention 1 d 4 60-90 Intervention group: 3-5 months after intervention Control group: 8-10 months after intervention STAI, PTSD-RI, IES-R ②④
Kazak et al.17/ USA Unlimited 11 18 Family cognitive behavior intervention 3 weeks 3 45 Once a week 2 months after intervention STAI, ASDS, IES-R ②④
Stehl et al.18/ USA Unlimited 76 76 Family cognitive behavior intervention 6 weeks 6 45 Once a week 1 month after intervention STAI, ASDS, IES-R ②④
Shekarabi-Ahari et al,19/ Iran Unlimited 10 10 Family cognitive behavior intervention 8 weeks 8 120 Once a week 2 months after intervention BYI
Marsland et al,20/ USA Unlimited 23 14 Family cognitive behavior intervention 12-18 weeks 6 30-60 Every 2-3 weeks 2 weeks after intervention STAI, BYI, IES ②③④
Cernvall et al.6/ Sweden Unlimited 31 27 Family cognitive behavior intervention 10 weeks 10 240 Once a week 12 months after intervention BYI, PCL-C ②③④
Tsitsi et al,21/ Cyprus Unlimited 29 25 Family relaxation therapy 3 weeks 3 25 Once a week 25 min each time 3 weeks after intervention HAM-A POMS ②③
Salem et al.22/ Denmark Unlimited 82 79 Family cognitive behavior intervention ≤24 weeks 7 60-90 Unclear 12 months after intervention SCL-92-R Harvard Trauma Questionnaire ②③

Strategy used to search the Web of Science.

No. Search strategy No. of documents
#1 ((TS = (“adolescent*” OR “teen*” OR “youth*” OR “child*” OR “infant*” OR “preschool” OR “minor*”)) OR Tl = (“adolescent*” OR “teen*” OR “youth*” OR “child*” OR “infant*” OR “preschool” OR “minor*”)) OR AB = (“adolescent*” OR “teen*” OR “youth*” OR “child*” OR “infant*” OR “preschool” OR “minor*”) 1,778,196
#2 ((TS = (“neoplasm*” OR “cancer*” OR “tumour*” OR “leukaemia”)) OR Tl = (“neoplasm*” OR “cancer*” OR “tumour*” OR “leukaemia”)) OR AB = (“neoplasm*” OR “cancer*” OR “tumour*” OR “leukaemia”) 3,171,886
#3 ((TS = (“family intervention” OR “family-based intervention” OR “family-centred intervention” OR “family psychosocial intervention” OR “family psychoeducation” OR “family therapy”)) OR Tl = (“family intervention” OR “family-based intervention” OR “family-centred intervention” OR “family psychosocial intervention” OR “family psychoeducation” OR “family therapy”)) OR AB=(“family intervention” OR “family-based intervention” OR “family-centred intervention” OR “family psychosocial intervention” OR “family psychoeducation” OR “family therapy”) 2363
#4 #1 AND #2 AND #3 39
eISSN:
2544-8994
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Medicine, Assistive Professions, Nursing