<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Objective</h3><p>This study evaluates the effectiveness of a dalethyne dressing for decreasing bacteria in diabetic patients with infected foot ulcers.</p></sec>
<sec><h3>Methods</h3><p>This study was conducted from March to September 2018 with a sample of 30 participants from the outpatient Kitamura Wound Clinic in Pontianak City, Indonesia. A quasi-experimental non-equivalent pretest–posttest control group design was used for the study. Participants were divided into two groups: an intervention group (treated with a dalethyne dressing) and a control group (treated with a standard dressing). Two trained research assistants collected the data using the Wagner wound classification system and a bacteria counter. The assistants swabbed each wound surface with sterile cotton, and the swabs were used to conduct a bacteria culture and count.</p></sec>
<sec><h3>Results</h3><p>The study population was 50% female and 50% male with no significant differences between each other in age, HbA1c, blood pressure, or ankle-brachial index (ABI; <italic>P</italic> > 0.05). Both groups had a significant reduction in the number of bacteria from the pretest to posttest (<italic>P</italic> &lt; 0.05). Mann–Whitney analysis of posttest data indicated a significant difference in bacteria reduction between the control group (median = 2.25) and the intervention group (median = 7.6; <italic>P</italic> = 0.018). It was noted that <italic>Staphylococcus aureus</italic> was found in the control group at posttest, but not in the intervention group.</p></sec>
<sec><h3>Conclusions</h3><p>This study provides evidence that a dalethyne dressing is effective for killing <italic>S. aureus</italic> in the infected foot ulcers of diabetic patients.</p></sec>
</abstract>

ObjectiveThis study evaluates the effectiveness of a dalethyne dressing for decreasing bacteria in diabetic patients with infected foot ulcers.
MethodsThis study was conducted from March to September 2018 with a sample of 30 participants from the outpatient Kitamura Wound Clinic in Pontianak City, Indonesia. A quasi-experimental non-equivalent pretest–posttest control group design was used for the study. Participants were divided into two groups: an intervention group (treated with a dalethyne dressing) and a control group (treated with a standard dressing). Two trained research assistants collected the data using the Wagner wound classification system and a bacteria counter. The assistants swabbed each wound surface with sterile cotton, and the swabs were used to conduct a bacteria culture and count.
ResultsThe study population was 50% female and 50% male with no significant differences between each other in age, HbA1c, blood pressure, or ankle-brachial index (ABI; P > 0.05). Both groups had a significant reduction in the number of bacteria from the pretest to posttest (P < 0.05). Mann–Whitney analysis of posttest data indicated a significant difference in bacteria reduction between the control group (median = 2.25) and the intervention group (median = 7.6; P = 0.018). It was noted that Staphylococcus aureus was found in the control group at posttest, but not in the intervention group.
ConclusionsThis study provides evidence that a dalethyne dressing is effective for killing S. aureus in the infected foot ulcers of diabetic patients.

The effectiveness of dalethyne dressings for reducing bacteria in diabetic foot ulcers

Department of Medical-Surgical Nursing, School of Nursing, Faculty of Medicine

Frontiers of Nursing

This work is licensed under the Creative Commons Attribution 4.0 International License.

ObjectiveThis study evaluates the effectiveness of a dalethyne dressing for decreasing bacteria in diabetic patients with infected foot ulcers.
MethodsThis...

Variables	Pretest (bacteria count × 10⁵ CFU/mL)			Posttest (bacteria count ×10⁵ CFU/mL)			P-value

	Mean	Median	SD	Mean	Median	SD
Control	30.19	63.7	683	23.80	2.25	37.62	0.004^*
Intervention	1946.50	227.0	2790	0.97	0.76	0.83	0.003^*

Bacteria type	Control n (%)		Intervention n (%)

	Pre (n = 15)	Post (n = 15)	Pre (n = 15)	Post (n = 15)
Staphylococcus aureus	8 (50)	10 (62.5)	10 (58.8)	–
Proteus mirabilis	3 (18.75)	3 (18.75)	1 (5.9)	1 (14.3)
Citrobacter freundii	3 (18.75)	3 (18.75)	2 (11.8)	3 (28.6)
Bacillus megaterium	2 (12.5)	–	–	–
Bacillus subtilis	–	–	4 (23.5)	4 (57.1)

Characteristics	n	%
Sex
Female	15	50
Male	15	50
Wound duration at week
1	11	36.7
2	12	40.0
3	6	20.0
4	1	3.3
DM duration in years
1–3	10	33.3
4–7	16	53.3
>7	4	13.3

Variables	Control group posttest		Intervention group posttest		P-value

	Median	95% CI	Median	95% CI
Bacteria count,×10⁵ CFU/mL	2.25	2.20–16.35	7.6	7.82–62.57	0.018^*

Items	Control group	Intervention group
Age	49.7 ± 8.4^*	52.5 ± 8.1^*
HbA1c	9.0 ± 1.0^*	9.6 ± 1.9^*
Blood pressure
Systole	122.9 ± 10.2^*	121.5 ± 10.1^*
Diastole	81.2 ± 9.0^*	78.8 ± 7.1^*
Ankle Brachial Index (ABI)	0.9 ± 0.07^*	0.9 ± 0.6^*

The effectiveness of dalethyne dressings for reducing bacteria in diabetic foot ulcers

Article Category: Original article

Published Online: Aug 18, 2021

Page range: 153 - 158

Received: Oct 25, 2020

Accepted: Nov 16, 2020

DOI: https://doi.org/10.2478/fon-2021-0017

Keywords
diabetic ulcer, dalethyne, infection, Staphylococcus aureus

© 2021 Suriadi Jais et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Figure 1

Pretest and posttest independent bacteria counts.

Type of bacteria present in pretest and posttest samples.

Participant characteristics.

Posttest bacteria count differences.

Differences between control group and intervention group (M±SD).

The effectiveness of dalethyne dressings for reducing bacteria in diabetic foot ulcers

Article Category: Original article

Published Online: Aug 18, 2021

Page range: 153 - 158

Received: Oct 25, 2020

Accepted: Nov 16, 2020

DOI: https://doi.org/10.2478/fon-2021-0017

Keywordsdiabetic ulcer, dalethyne, infection, Staphylococcus aureus

© 2021 Suriadi Jais et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Figure 1

Pretest and posttest independent bacteria counts.

Type of bacteria present in pretest and posttest samples.

Participant characteristics.

Posttest bacteria count differences.

Differences between control group and intervention group (M±SD).

Keywords
diabetic ulcer, dalethyne, infection, Staphylococcus aureus