<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Background</h3>
<p>The aim of this study was to compare the dosimetry of carotid arteries (CAs) using three radiation therapy (RT) techniques, three-dimensional conformal RT (3D-CRT), helical tomotherapy-intensity-modulated RT (HT-IMRT), and volumetric modulated arc therapy (VMAT), in patients with early-stage glottic cancer.</p>
</sec>
<sec><h3>Patients and Methods</h3>
<p>A retrospective analysis of 28 patients was performed, and the right and left CAs were delineated. Mean and maximum dose (Dmax) values were compared across the three treatment techniques.</p>
</sec>
<sec><h3>Results</h3>
<p>The results indicate that 3D-CRT plans had the highest mean and maximum doses to CAs, while VMAT plans had the lowest doses.</p>
</sec>
<sec><h3>Conclusions</h3>
<p>Our study demonstrates the feasibility of sparing CAs with newer RT modalities. Further clinical studies are needed to determine if these techniques can reduce carotid stenosis-related events.</p>
</sec>
</abstract>

Background
The aim of this study was to compare the dosimetry of carotid arteries (CAs) using three radiation therapy (RT) techniques, three-dimensional conformal RT (3D-CRT), helical tomotherapy-intensity-modulated RT (HT-IMRT), and volumetric modulated arc therapy (VMAT), in patients with early-stage glottic cancer.

Patients and Methods
A retrospective analysis of 28 patients was performed, and the right and left CAs were delineated. Mean and maximum dose (Dmax) values were compared across the three treatment techniques.

Results
The results indicate that 3D-CRT plans had the highest mean and maximum doses to CAs, while VMAT plans had the lowest doses.

Conclusions
Our study demonstrates the feasibility of sparing CAs with newer RT modalities. Further clinical studies are needed to determine if these techniques can reduce carotid stenosis-related events.

Comparison of Carotid Artery Dose in Early-Stage Glottic Cancer Treated with 3D-Conformal, Helical-IMRT and VMAT

Portuguese Institute of Oncology of Coimbra

Forum of Clinical Oncology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Background
The aim of this study was to compare the dosimetry of carotid arteries (CAs) using three radiation therapy (RT) techniques, three-dimensional...

Comparison of Carotid Artery Dose in Early-Stage Glottic Cancer Treated with 3D-Conformal, Helical-IMRT and VMAT

Article Category: Research Article

Published Online: Nov 13, 2023

Page range: 23 - 30

Received: Jun 19, 2023

Accepted: Oct 07, 2023

DOI: https://doi.org/10.2478/fco-2023-0009

Keywords
Glottic Cancer, Carotid Arteries Dose, 3D-CRT, HT-IMRT, VMAT

© 2023 B Pires et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Comparison of Carotid Artery Dose in Early-Stage Glottic Cancer Treated with 3D-Conformal, Helical-IMRT and VMAT

Article Category: Research Article

Published Online: Nov 13, 2023

Page range: 23 - 30

Received: Jun 19, 2023

Accepted: Oct 07, 2023

DOI: https://doi.org/10.2478/fco-2023-0009

KeywordsGlottic Cancer, Carotid Arteries Dose, 3D-CRT, HT-IMRT, VMAT

© 2023 B Pires et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
Glottic Cancer, Carotid Arteries Dose, 3D-CRT, HT-IMRT, VMAT