[1. Hoffmann, D. and E. L. Wynder: Identification of polynuclear aromatic hydrocarbons; 136th National Meeting of the American Chemical Society (Am. Chem. Soc.), Atlantic City, NJ, 1959, No. 16U.]Search in Google Scholar
[2. Wynder, E. L. and D. Hoffmann: A Study of Tobacco Carcinogenesis. VII. The role of higher polycyclic hydrocar-bons; Cancer 12 (1959) 1079–1086.]Search in Google Scholar
[3. Wynder, E. L. and D. Hoffmann: The carcinogenicity of benzofluoranthenes; Cancer 12 (1959) 1194–1199.]Search in Google Scholar
[4. Hoffmann, D. and E. L. Wynder: On the isolation and identification of polycyclic aromatic hydrocarbons; Cancer 13 (1960) 1062–1073.]Search in Google Scholar
[5. Hoffmann, D. and E. L. Wynder: Short-term determination of carcinogenic aromatic hydrocarbons; Anal. Chem. 32 (1960) 295.]Search in Google Scholar
[6. Wynder, E. L. and D. Hoffmann: Studies in tobacco carcinogenesis; Proc. American Association for Cancer Research (Am. Assoc. Cancer Res.), 3 (1960) 164.]Search in Google Scholar
[7. Wynder, E. L. and D. Hoffmann: Some practical aspects of the smoking-cancer problem; New Engl. J. Med. 262 (1960) 540–545.]Search in Google Scholar
[8. Wynder, E. L. and D. Hoffmann: Tobacco smoking as a cause of cancer; in: Cancer Progress; edited by R. W. Raven, Butter-worths, London, UK, 1960, pp. 77–80.]Search in Google Scholar
[9. Biekert, E., D. Hoffmann, and L. Enslein: Über 1. 4-Oxazine. IV. Kondensation von 1. 2-Amino-alkoholen mit a-Ketocarbonsäure-estern zu 5. 6-Dihydro-1. 4-oxazinonen-(2); Chem. Ber. 94 (1961) 2778–2785.]Search in Google Scholar
[10. Biekert, E., D. Hoffmann, and F. J. Meyer: Über 1. 4-Oxazine. I. Darstellung kondensierter 1. 4-Oxazinone-(2) durch Umset- zung von o-Aminophenolen mit -Ketoestern; Chem. Ber. 94 (1961) 1664–1675.]Search in Google Scholar
[11. Biekert, E., D. Hoffmann, and F. J. Meyer: Über 1. 4-Oxazine. II. Überführung der 1. 4-Benzoxazinone-(2) in Phen-morpholone-(2) und N-substituierte Aminoalkohole; Chem. Ber. 94 (1961) 1676–1682.]Search in Google Scholar
[12. Hoffmann, D. and E. L. Wynder: Die quantitative Bestim-mung von Phenolen im Tabakrauch; Beitr. Tabakforsch. 1 (1961) 101–106.]Search in Google Scholar
[13. Wynder, E. L. and D. Hoffmann: Biological and chemical studies of tobacco smoke condensate; Proc. Am. Assoc. Cancer Res. 3 (1961) 280.]Search in Google Scholar
[14. Wynder, E. L. and D. Hoffmann: Carcinogenicity of di-benzo(a,1)pyrene; Nature 192 (1961) 1092–1093.]Search in Google Scholar
[15. Wynder, E. L. and D. Hoffmann: Present status of laboratory studies on tobacco carcinogenesis; Acta Pathol. Microbiol. Scand. 52 (1961) 119–132.]Search in Google Scholar
[16. Wynder, E. L. and D. Hoffmann: A Study of Tobacco Carcinogenesis. VIII. The role of the acidic fractions as promoters; Cancer 14 (1961) 1306–1315.]Search in Google Scholar
[17. Hoffmann, D. and E. L. Wynder: Analytical and biological studies on gasoline engine exhaust; National Cancer Institute (NCI) Monogr. 9 (1962) 91–116.]Search in Google Scholar
[18. Hoffmann, D. and E. L. Wynder: A Study of Air Pollution Carcinogenesis. II. The isolation and identification of polynu-clear aromatic hydrocarbons from gasoline engine exhaust condensate; Cancer 15 (1962) 93–102.]Search in Google Scholar
[19. Wynder, E. L. and D. Hoffmann: A Study of Air Pollution Carcinogenesis. III. Carcinogenic activity of gasoline engine exhaust condensate; Cancer 15 (1962) 103–108.]Search in Google Scholar
[20. Wynder, E. L. and D. Hoffmann: Air pollution and lung cancer; Proc. Natl. Conf. on Air Pollution, US Public Health Service Publ. No. 1022, 1962, pp. 143–148.]Search in Google Scholar
[21. Wynder, E. L. and D. Hoffmann: Studies with gaseous and particulate phase of tobacco smoke; 53rd Ann. Meeting Am. Assoc. Cancer Res., 1962, pp. 373.]Search in Google Scholar
[22. Wynder, E. L. and D. Hoffmann: The role of skin neoplasia in tobacco carcinogenesis; in: Tobacco and Health; edited by G. G. James and R. Rosenthal, Thomas, Springfield, IL, 1962, pp. 61-71.]Search in Google Scholar
[23. Hoffmann, D., G. Rathkamp, and E. L. Wynder: Comparison of the yields of several selected components in the smoke from different tobacco products; J. Natl. Cancer Inst. 31 (1963) 627-637.]Search in Google Scholar
[24. Hoffmann, D. and E. L. Wynder: Filtration of phenols from cigarette smoke; J. Natl. Cancer Inst. 30 (1963) 67-84.]Search in Google Scholar
[25. Hoffmann, D. and E. L. Wynder: Die Filtration von Phenolen aus Cigarettenrauch; Beitr. Tabakforsch. 2 (1963) 51-66.]Search in Google Scholar
[26. Hoffmann, D. and E. L. Wynder: Studies on Gasoline Engine Exhaust; J. Air Pollut. Control Assoc. 13 (1963) 322-327.10.1080/00022470.1963.10468184]Search in Google Scholar
[27. Wynder, E. L. and D. Hoffmann: Bioassay s on the carcinoge-nicity of tobacco smoke condensate and air pollutants; Proc. Am. Assoc. Cancer Res. 4 (1963) 73.]Search in Google Scholar
[28. Wynder, E. L. and D. Hoffmann: Experimental aspects of tobacco carcinogenesis; Dis. Chest 44 (1963) 337-344.]Search in Google Scholar
[29. Wynder, E. L. and D. Hoffmann: Ein experimenteller Beitrag zur Tabakrauchkanzerogenese [An experimental contribution to the problem of tobacco smoke carcinogenesis]; Dtsch. Med. Wochenschr. 88 (1963) 623-628.]Search in Google Scholar
[30. Wynder, E. L., H. E. Kaiser, D. A. Goodman, and D. Hoffmann: A method for determining ciliastatic components in cigarette smoke; Cancer 16 (1963) 1222-1225.]Search in Google Scholar
[31. Hoffmann, D., G. Rathkamp, and E. L. Wynder: Vergleich der Ausbeute an mehreren ausgewählten Komponenten im Rauch verschiedener Tabakerzeugnisse; Beitr. Tabakforsch. 2 (1964) 123-130.]Search in Google Scholar
[32. Wynder, E. L. and D. Hoffmann: Experimental tobacco carcinogenesis; Adv. Cancer Res. 8 (1964) 249–453.10.1016/S0065-230X(08)60510-2]Search in Google Scholar
[33. Hoffmann, D., E. Theisz, and E. L. Wynder: Studies on the carcinogenicity of gasoline exhaust; J. Air Pollut. Control Assoc. 15 (1965) 162-165.10.1080/00022470.1965.10468353]Search in Google Scholar
[34. Wynder, E. L., D. A. Goodman, and D. Hoffmann: Ciliatoxic Components in Cigarette Smoke. II. Carboxylic acids and aldehydes; Cancer 18 (1965) 505-509.]Search in Google Scholar
[35. Wynder, E. L., D. A. Goodman, and D. Hoffmann: Ciliatoxic Components in Cigarette Smoke. III. In vitro comparison of different smoke components; Cancer 18 (1965) 1652-1658.]Search in Google Scholar
[36. Wynder, E. L. and D. Hoffmann: Reduction of tumorigenicity of cigarette smoke; JAMA 192 (1965) 88-94.]Search in Google Scholar
[37. Wynder, E. L. and D. Hoffmann: Some laboratory and epi-demiological aspects of air pollution carcinogenesis; J. Air Pollut. Control Assoc. 15 (1965) 155-159.]Search in Google Scholar
[38. Wynder, E. L., D. Hoffmann, and O. Auerbach: The role of particulate and volatile components in tobacco carcinogenesis; Proc. Am. Assoc. Cancer Res. 6 (1965) 69.]Search in Google Scholar
[39. Hoffmann, D. and J. Rubin: Chemical Studies on Tobacco Smoke. I. the Quantitative Determination of Indoles in Cigarette Smoke; Beitr. Tabakforsch. 3 (1966) 409–414.]Search in Google Scholar
[40. Hoffmann, D. and E. L. Wynder: The tumor initiators in tobacco smoke; Proc. Am. Assoc. Cancer Res. 7 (1966) 32.]Search in Google Scholar
[41. Hoffmann, D. and E. L. Wynder: Beitrag zur carzinogenen Wirkung von Dibenzopyrenen; Z. Krebsforsch. 68 (1966) 137-149.]Search in Google Scholar
[42. Rathkamp, G., D. Hoffmann, and E. L. Wynder: Experiments on the reduction of polynuclear aromatic hydrocarbons in cigarette smoke; presented at the 20th Tobacco Chemists’ Research Conference (TCRC), Winston-Salem, NC, 1966, No. 19.]Search in Google Scholar
[43. Woziwodzki, H. and D. Hoffmann: Free higher fatty acids in tobacco and tobacco smoke; presented at the 20th TCRC, Winston-Salem, NC, 1966, No. 16.]Search in Google Scholar
[44. Wynder, E. L. and D. Hoffmann: Beziehungen zwischen Epidemiologie und experimenteller Karzinogenese; Münch. Med. Wochenschr. 108 (1966) 1501-1512.]Search in Google Scholar
[45. Wynder, E. L. and D. Hoffmann: Current concepts of environ-mental cancer research; Med. Clin. North Am. 50 (1966) 631-650.]Search in Google Scholar
[46. Hoffmann, D., G. Rathkamp, and J. Rubin: Chemical Studies on Tobacco Smoke. II. Comparison of the yields of several selected components in the smoke from five major Turkish tobacco varieties; Food Cosmet. Toxicol. 5 (1967) 37-38.]Search in Google Scholar
[47. Hoffmann, D. and E. L. Wynder: The reduction of the tumorigenicity of cigarette smoke condensate by addition of sodium nitrate to tobacco; Cancer Res. 27 (1967) 172-174.]Search in Google Scholar
[48. Rathkamp, G., D. Hoffmann, and E. L. Wynder: Primary and secondary nitrohydrocarbons in cigarette smoke; presented at the 21st TCRC, Durham, NC, 1967, No. 25.]Search in Google Scholar
[49. Wynder, E. L. and D. Hoffmann: Nutrition and Cancer; in: Prevention of Cancer; edited by R. W. Raven and F. J. C. Roe, Butterworths, London, England, 1967, pp. 11-18.]Search in Google Scholar
[50. Wynder, E. L. and D. Hoffmann: Tobacco and Tobacco Smoke. Studies in Experimental Carcinogenesis; Academic Press, New York, NY, 1967.]Search in Google Scholar
[51. Hoffmann, D. and G. Rathkamp:. Chemical Studies on Tobacco Smoke. III. Primary and Secondary Nitroalkanes in Cigarette Smoke; Beitr. Tabakforsch. 4 (1968) 124-134.]Search in Google Scholar
[52. Hoffmann, D. and G. Rathkamp: Chemical Studies on Tobacco Smoke. V. Quantitative Determination of Chlori-nated Hydrocarbon Insecticides in Cigarette Tobacco and its Smoke; Beitr. Tabakforsch. 4 (1968) 201-214.]Search in Google Scholar
[53. Hoffmann, D., G. Rathkamp, and H. Woziwodzki: Chemical Studies on Tobacco Smoke. VI. The Determination of Carba-zoles in Cigarette Smoke; Beitr. Tabakforsch. 4 (1968) 253-263.]Search in Google Scholar
[54. Hoffmann, D. and H. Woziwodzki: Chemical Studies on Tobacco Smoke. IV. The Quantitative Determination of Free Nonvolatile Fatty Acids in Tobacco and Tobacco Smoke; Beitr. Tabakforsch. 4 (1968) 167-175.]Search in Google Scholar
[55. Hoffmann, D. and E. L. Wynder: Chemical Analysis and Carcinogenic Bioassays of Organic Particulate Pollutants, in: Air Pollution, Vol. II: Analysis, Monitoring and Surveying; edited by A. C. Stern, Academic Press, New York, NY, 1968, pp. 187-247.]Search in Google Scholar
[56. Hoffmann, D. and E. L. Wynder: Selective reduction of the tumorigenicity of tobacco smoke. Experimental approaches; NCI Monogr. 28 (1968) 151-172.]Search in Google Scholar
[57. Masuda, Y., D. Hoffmann, and E. L. Wynder: a-Naphthyl-amine and P-naphthy lamine in cigarette smoke; presented at the 22nd TCRC, Richmond, VA, 1968, No. 22.]Search in Google Scholar
[58. Wynder, E. L. and D. Hoffmann: Experimental tobacco carcinogenesis; Science 162 (1968) 862-871.]Search in Google Scholar
[59. Wynder, E. L. and D. Hoffmann: Tobacco and Tobacco Smoke; Nature 219 (1968) 661-662.]Search in Google Scholar
[60. Wynder, E. L. and D. Hoffmann: Selected laboratory methods in tobacco carcinogenesis; in: Methods in Cancer Research, Vol. 4; edited by E. H. Busch, Academic Press, New York, NY, 1968, pp. 3-52.]Search in Google Scholar
[61. Wynder, E. L. and D. Hoffmann (Editors): Toward a less harmful cigarette; NCI Monograph 28, American Cancer Society, Bethesda, MD, 1968.]Search in Google Scholar
[62. Wynder, E. L., K. T. Taguchi, V. Baden, and D. Hoffmann: A Study of Tobacco Carcinogenesis. IX. The effect of cigarette smoke on the respiratory tract of mice after passive inhalation; Cancer 21 (1968) 134-153.]Search in Google Scholar
[63. Hoffmann, D., Y. Masuda, and E. L. Wynder: a-Naphthyl-amine and P-naphthy lamine in cigarette smoke; Nature 221 (1969) 254–256.]Search in Google Scholar
[64. Hoffmann, D., G. Rathkamp, and S. Nesnow: [Chemical Studies on Tobacco Smoke. VIII.] Quantitative determination of 9-methylcarbazoles in cigarette smoke; Anal. Chem. 41 (1969) 1256-1259.]Search in Google Scholar
[65. Hoffmann, D., G. Rathkamp, and E. L. Wynder: Chemical Studies on Tobacco Smoke. IX. Quantitative Analysis of Chlorinated Hydrocarbon Insecticides; Beitr. Tabakforsch. 5 (1969) 140-148.]Search in Google Scholar
[66. Masuda, Y. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. VII.] Quantitative determination of 1-naphthylamine and 2-naphthylamine in cigarette smoke; Anal. Chem. 41 (1969) 650–652.]Search in Google Scholar
[67. Masuda, Y. and D. Hoffmann: A method for the determination of primary amines of polynuclear aromatic hydrocarbons; J. Chromatogr. Sci. 7 (1969) 694–697.]Search in Google Scholar
[68. Mazzola, V., G. Rathkamp, and D. Hoffmann: N-Alkyl-indoles, N-alkylcarbazoles, and Dibenzofurans in Cigarette Smoke; presented at the 23rd TCRC, Philadelphia, PA, 1969, No. 22.]Search in Google Scholar
[69. Radford, E. P., V. R. Hunt, J. B. Little, E. L. Wynder, and D. Hoffmann: Carcinogenicity of Tobacco-smoke Constituents; Science 165 (1969) 312–313.]Search in Google Scholar
[70. Rathkamp, G. and D. Hoffmann: The inhibition of the pyrosynthesis of several selective smoke components. Experimental findings and theoretical considerations; pre-sented at the 23rd TCRC, Philadelphia, PA, 1969, No. 29.]Search in Google Scholar
[71. Wynder, E. L. and D. Hoffmann: Current studies on etiology and prevention; in: Lung Cancer: a study of 5,000 Memorial Hospital cases; edited by E. L. Watson, Mosby Company, St. Louis, MO, 1969, pp. 15–34.]Search in Google Scholar
[72. Wynder, E. L. and D. Hoffmann: A Study of Tobacco Carcinogenesis. X. Tumor promoting activity; Cancer 24 (1969) 289–301.]Search in Google Scholar
[73. Wynder, E. L. and D. Hoffmann: Bioassays in tobacco carcinogenesis; Prog. Exp. Tumor Res. 11 (1969) 163–193.]Search in Google Scholar
[74. Hoffmann, D. and V. Mazzola: Chemical Studies on Tobacco Smoke. XI. Dibenzofurans in Cigarette Smoke; Beitr. Tabak-forsch. 5 (1970) 183–188.]Search in Google Scholar
[75. Hoffmann, D. and G. Rathkamp: [Chemical Studies on Tobacco Smoke. X.] Quantitative determination of 1-alkyl-indoles in cigarette smoke; Anal. Chem. 42 (1970) 366–370.]Search in Google Scholar
[76. Hoffmann, D. and G. Rathkamp: Chemical Studies on Tobacco Smoke. XII. Quantitative determination of nitroben-zenes in cigarette smoke; Anal. Chem. 42 (1970) 1643–1647.]Search in Google Scholar
[77. Hoffmann, D. and E. L. Wynder: Chamber development and aerosol dispersion; in: Inhalation Carcinogenesis; edited by H. G. Hanna et al., US Atomic Energy Symp. Ser. 18, Washington, DC, 1970, pp. 173–191.]Search in Google Scholar
[78. Rathkamp, G. and D. Hoffmann: Fluorenes and fluoranthenes in cigarette smoke; presented at the 24th TCRC, Montreal, Canada, 1970, No. 28.]Search in Google Scholar
[79. Rathkamp, G. and D. Hoffmann: Chemical Studies on Tobacco Smoke. XIII. Inhibition of the Pyrosyntheses of Several Selective Smoke Constituents; Beitr. Tabakforsch. 5 (1970) 302–306.]Search in Google Scholar
[80. Wynder, E. L. and D. Hoffmann: the Epidermis and the Respiratory Tract as Bioassay Systems in Tobacco Carcinoge-nesis; Brit. J. Cancer 24 (1970) 574–587.]Search in Google Scholar
[81. Hoffma nn, D. and J. Vai s: Ana lysis of vola tile N-nitrosami n es in unaged mainstream smoke of cigarettes; presented at the 25th TCRC, Louisville, KY, 1971, No. 23.]Search in Google Scholar
[82. Hoffmann, D. and E. L. Wynder: A Study of Tobacco Carcinogenesis. XI. Tumor initiators, tumor accelerators, and tumor promoting activity of condensate fractions; Cancer 27 (1971) 848–864.]Search in Google Scholar
[83. Marquardt, H., A. Bendich, F. S. Phillips, and D. Hoffmann: Binding of [G-3H]-7,12-dimethylbenz(a)anthracene to DNA of normal and of rapidly dividing hepatic cells of rats; Chem. Biol. Interactions 3 (1971) 1–11.]Search in Google Scholar
[84. Rathkamp, G., T. C. Tso, and D. Hoffmann: On the correlation between various leaf constituents and selected smoke com-pounds; presented at the 25th TCRC, Louisville, KY, 1971, No. 6.]Search in Google Scholar
[85. Singer, G. and D. Hoffmann: 4-N-Alkylaminophenols in cigarette smoke; presented at the 25th TCRC, Louisville, KY, 1971, No. 22.]Search in Google Scholar
[86. Wynder, E. L. and D. Hoffmann: Carcinogens in the air; Proc. 24th Ann. Symp. on Fundamental Cancer Research, Houston, TX, Williams & Wilkens, Baltimore, MD, 1971, pp. 118–141.]Search in Google Scholar
[87. Wynder, E. L., D. Hoffmann, P. Ashwanden, and R. Wachs-muth (Eds.): Less harmful ways of smoking; Proc. of a Workshop of the 2nd World Conf. on Smoking and Health, London, UK, 1971.]Search in Google Scholar
[88. Brunnemann, K. D. and D. Hoffmann: On the pH of tobacco smoke; presented at the Joint Conference CORESTA and 26th TCRC, Williamsburg, VA, 1972, No. 11.]Search in Google Scholar
[89. Hoffmann, D.: Benzo[a]pyrene in polluted air; Prev. Med. 1 (1972) 450–451.]Search in Google Scholar
[90. Hoffmann, D. and G. Rathkamp: [Chemical Studies on Tobacco Smoke. XIV.] Quantitative determination of fluor-enes in cigarette smoke and their formation by pyrosynthe-sis; Anal. Chem. 44 (1972) 899–904.]Search in Google Scholar
[91. Hoffmann, D., G. Rathkamp, S. Nesnow, and E. L. Wynder: [Chemical Studies on Tobacco Smoke. XVI.] Fluoranthenes: Quantitative determination in cigarette smoke, formation by pyrolysis, and tumor initiating activity; J. Natl. Cancer Inst. 49 (1972) 1165–1175.]Search in Google Scholar
[92. Hoffmann, D. and E. L. Wynder: Chemical Studies on Tobacco Smoke. XV. Chemical Composition and Tumori-genicity of Tobacco Smoke; in: The Chemistry of Tobacco and Tobacco Smoke; edited by I. Schmeltz, Plenum Press, New York, NY, 1972, pp. 123–147.]Search in Google Scholar
[93. Hoffmann, D. and E. L. Wynder: [Chemical Studies on Tobacco Smoke. XVIII.] Smoke of cigarettes and little cigars: An analytical comparison; Science 178 (1972) 1197–1199.]Search in Google Scholar
[94. Hoffmann, D. and E. L. Wynder: Respiratory Carcinogens: Their Nature and Precursors; in: Identification and measure-ment of environmental pollutants: proceedings of a sympo-sium; edited by B. Westley, Campbell Printing, Ottawa, Canada, 1972, pp. 9–16.]Search in Google Scholar
[95. Hoffmann, D. and E. L. Wynder: Selective Reduction of the Tumorigenicity of Tobacco Smoke. II. Experimental approaches; J. Natl. Cancer Inst. 48 (1972) 1855–1868.]Search in Google Scholar
[96. Rathkamp, G. and D. Hoffmann: Polynuclear aromatic hydrocarbon profile of tobacco smoke; presented at the Joint Conference CORESTA and 26th TCRC, Williamsburg, VA, 1972, No. 09.]Search in Google Scholar
[97. Wynder, E. L. and D. Hoffmann: Less harmful ways of smoking; J. Natl. Cancer Inst. 48 (1972) 1749–1758.]Search in Google Scholar
[98. Brunnemann, K. D., D. Hoffmann, and E. L. Wynder: Studies on the inhalability of cigarette and cigar smoke; presented at the 27th TCRC, Winston-Salem, NC, 1973, No. 27.]Search in Google Scholar
[99. Hecht, S. S., W. E. Bondinell, and D. Hoffmann: Isolation and identification of alkylchrysenes in cigarette smoke; pre-sented at the 27th TCRC, Winston-Salem, NC, 1973, No. 32.]Search in Google Scholar
[100. Hoffmann, D., G. Rathkamp, K. D. Brunnemann, and E. L. Wynder: [Chemical Studies on Tobacco Smoke. XXII.] On the profile analysis of tobacco smoke. Sci. Total Environ. 2 (1973) 157–171.]Search in Google Scholar
[101. Liu, Y. Y. and D. Hoffmann: Maleic hydrazide and volatile hydrazines in cigarette smoke; presented at the 27th TCRC, Winston-Salem, NC, 1973, No. 29.]Search in Google Scholar
[102. Liu, Y. Y. and D. Hoffmann: Chemical Studies on Tobacco Smoke. XIX. Quantitative chromatographic determination of maleic hydrazide in cigarette smoke; Anal. Chem. 45 (1973) 2270–2273.]Search in Google Scholar
[103. Rathkamp, D., D. K. Chao, and D. Hoffmann: Analytical studies on nonvolatile N-nitrosamines in cigarette smoke; presented at the 27th TCRC, Winston-Salem, NC, 1973, No. 26.]Search in Google Scholar
[104. Rathkamp, G., T. C. Tso, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XX. Smoke Analysis of Ciga-rettes Made from Bright Tobaccos Differing in Variety and Stalk Positions; Beitr. Tabakforsch. 7 (1973) 179–189.]Search in Google Scholar
[105. Schmeltz, I. and D. Hoffmann: Formation of polynuclear aromatic hydrocarbons from combustion of organic matter; in: Carcinogenesis. Polynuclear aromatic hydrocarbons: Chemistry, metabolism, and carcinogenesis; edited by R. I. Freudenthal and P. I. Jones, Raven Press, New York, NY (1973) 225–239.]Search in Google Scholar
[106. Tso, T. C., G. Rathkamp, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXI. Correlation and Multiple Regression among Selected Cigarette-smoke Constituents and Leaf Characteristics of Bright Tobacco; Beitr. Tabak-forsch. 7 (1973) 190–194.]Search in Google Scholar
[107. Brunnemann, K. D. and D. Hoffmann: Gas chromatographic determination of ammonia in cigarette and cigar smoke; presented at the 28th TCRC, Raleigh, NC, 1974, No. 53.]Search in Google Scholar
[108. Brunnemann, K. D. and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXIV. A quantitative method for carbon monoxide and carbon dioxide in cigarette and cigar smoke; J. Chromatogr. Sci. 12 (1974) 70–75.]Search in Google Scholar
[109. Brunnemann, K. D. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XXV.] The pH of tobacco smoke; Food Cosmet. Toxicol. 12 (1974) 115–124.]Search in Google Scholar
[110. Hecht, S. S., E. W. Bondinell, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXIX. Chrysene and methyl-chrysenes: Presence in tobacco and carcinogenicity; J. Natl. Cancer Inst. 53 (1974) 1121–1133.]Search in Google Scholar
[111. Hecht, S. S., R. M. Ornaf, and D. Hoffmann: N-nitroso-alkaloids in tobacco; presented at the 28th TCRC, Raleigh, NC, 1974, No. 36.]Search in Google Scholar
[112. Hecht, S. S., R. L. Thorne, and D. Hoffmann: Studies of tumor promoters in tobacco smoke; presented at the 28th TCRC, Raleigh, NC, 1974, No. 42.]Search in Google Scholar
[113. Hoffmann, D., W. E. Bondinell, and E. L. Wynder: Carcino-genicity of methylchrysenes; Science 183 (1974) 215–216.]Search in Google Scholar
[114. Hoffmann, D., S. S. Hecht, and R. M. Ornaf: Nonvolatile N-nitrosamines in tobacco and tobacco smoke; presented at the CORESTA Symposium Montreux, Suisse, 1974, No. 36.]Search in Google Scholar
[115. Hoffmann, D., S. S. Hecht, R. M. Ornaf, and E. L. Wynder: [Chemical Studies on Tobacco Smoke. XXX.] N’-Nitrosonornicotine in tobacco; Science 186 (1974) 265–267.]Search in Google Scholar
[116. Hoffmann, D., G. Rathkamp, and Y. Y. Liu: Chemical Studies on Tobacco Smoke. XXVI. On the isolation and identification of volatile and non-volatile N-nitrosamines and hydrazines in cigarette smoke; in: N-Nitroso Com-pounds in the Environment, IARC Sci. Publ. 9 (1974) 159–165.]Search in Google Scholar
[117. Hoffmann, D., L. D. Sanghvi, and E. L. Wynder: [Chemical Studies on Tobacco Smoke. XXVIII.] Comparative chemical analysis of Indian bidi and American cigarette smoke; Int. J. Cancer 14 (1974) 49–53.]Search in Google Scholar
[118. Hoffmann, D. and E. L. Wynder: Positive Controls in Environmental Respiratory Carcinogenesis; in: Carcinogene-sis Testing of Chemicals; edited by L. Goldberg, CRC Press, Cleveland, OH, 1974, pp. 35–39.]Search in Google Scholar
[119. Hu, M. W., W. E. Bondinell, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXIII. Synthesis of carbon-14 labelled myosmine, nornicotine, and N’-nitrosonornicotine; J. Labelled Compd. 10 (1974) 79–88.]Search in Google Scholar
[120. Kobayashi, N., D. Hoffmann, and E. L. Wynder: A Study of Tobacco Carcinogenesis. XII. Epithelial changes induced in the upper respiratory tracts of Syrian golden hamsters by cigarette smoke; J. Natl. Cancer Inst. 53 (1974) 1085–1089.]Search in Google Scholar
[121. Liu, Y. Y., I. Schmeltz, and D. Hoffmann: Chemical studies on tobacco smoke [XXVII]. Quantitative analysis of hydra-zine in tobacco and cigarette smoke; Anal. Chem. 46 (1974) 885–889.]Search in Google Scholar
[122. Schmeltz, I., A. de Paolis, and D. Hoffmann: Quantitative analyses of major phytosterols in tobacco and tobacco smoke; presented at the 28th TCRC, Raleigh, NC, 1974, No. 43.]Search in Google Scholar
[123. Schmeltz, I., D. Hoffmann, and E. L. Wynder: [Chemical Studies on Tobacco Smoke. XXXII.] Toxic and Tumorigen-ic Agents in Tobacco Smoke: Analytical Methods and Modes of Origin; Proceedings of the 8th Ann. Conf. on Trace Substances in Environmental Health; edited by D. D. Hem-phill, University of Missouri, Columbia, MO, 1974, pp. 281–295.]Search in Google Scholar
[124. Wynder, E. L., K. Mabuchi, and D. Hoffmann: Tobacco; in: Cancer Epidemiology and Prevention; edited by D. Schottenfeld, Charles C. Thomas Publ., Springfield, IL, 1974, pp. 102–125.]Search in Google Scholar
[125. Brunnemann, K. D. and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXXIV. Gas chromatographic determination of ammonia in cigarette and cigar smoke; J. Chroma-togr. Sci. 13 (1975) 159–163.]Search in Google Scholar
[126. Brunnemann, K. D., C. -H. Lee, and D. Hoffmann: A Study of the Precursors and on the Quantitative Analysis of Catechols in Cigarette Smoke; presented at the 29th TCRC, College Park, MD, 1975, No. 46.]Search in Google Scholar
[127. Hecht, S. S., M. Loy, R. R. Maronpot, and D. Hoffmann: A Study of Chemical Carcinogenesis: Comparative carcinoge-nicity of 5-methylchrysene, benzo(a)pyrene and modified chrysenes. Cancer Lett., 1 (1975) 147–153.]Search in Google Scholar
[128. Hecht, S. S., R. M. Ornaf, C. B. Chen, D. Hoffmann, and T. C. Tso; On the Origin of N-Nitrosonornicotine in Tobacco; pre-sented at the 29th TCRC, College Park, MD, 1975, No. 34.]Search in Google Scholar
[129. Hecht, S. S., R. M. Ornaf, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XLI.] Determination of N’-nitrosonornicotine in tobacco by high speed liquid chroma-tography; Anal. Chem. 47 (1975) 2046–2048.]Search in Google Scholar
[130. Hecht, S. S., R. M. Ornaf, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXXIII. N’-Nitrosonornicotine in tobacco: Analysis of possible contributing factors and biologic implications; J. Natl. Cancer Inst. 54 (1975) 1237–1244.]Search in Google Scholar
[131. Hecht, S. S., R. L. Thorne, R. R. Maronpot, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XIII. Tumor promoting subfractions of the weakly acidic fraction; J. Natl. Cancer Inst. 55 (1975) 1329–1336.]Search in Google Scholar
[132. Hoffmann, D., K. D. Brunnemann, G. B. Gori, and E. L. Wynder: On the carcinogenicity of marijuana smoke; Rec. Adv. Phytochem. 9 (1975) 63–81.]Search in Google Scholar
[133. Hoffmann, D., S. S. Hecht, I. Schmeltz, K. D. Brunnemann, and E. L. Wynder: Chemical Studies on Tobacco Smoke. XLIV. New separation techniques for classes of smoke compounds; Rec. Adv. Tobacco Sci. 1 (1975) 97–122.]Search in Google Scholar
[134. Hoffmann, D., C. P. Patrianakos, K. D. Brunnemann and G. B. Gori: On the Analysis of Vinyl Chloride in Tobacco Smoke; presented at the 29th TCRC, College Park, MD, 1975, No. 17.]Search in Google Scholar
[135. Hoffmann, D., R. Raineri, S. S. Hecht, R. R. Maronpot, and E. L. Wynder: A Study of Tobacco Carcinogenesis. XIV. Effect of N’-nitrosonornicotine and N’-nitrosoanabasine in rats; J. Natl. Cancer Inst. 55 (1975) 977–981.]Search in Google Scholar
[136. Hoffmann, D. and E. L. Wynder: New Separation Techniques for Classes of Smoke Compounds; presented at the 29th TCRC, College Park, MD, 1975, No. 5.]Search in Google Scholar
[137. Hoffmann, D. and E. L. Wynder: Chemical Studies on Tobacco Smoke. XLIII. The active fractions of cigarette smoke in experimental tobacco carcinogenesis. A review; Tobacco Res. (India) 1 (1975) 88–97.]Search in Google Scholar
[138. Schmeltz, I., K. D. Brunnemann, D. Hoffmann, and A. Cornell: On the chemistry of cigar smoke: comparisons between experimental little and large cigars; presented at the 29th TCRC, College Park, MD, 1975, No. 41.10.2478/cttr-2013-0405]Search in Google Scholar
[139. Schmeltz, I., A. de Paolis, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XXXI.] Phytosterols in Tobacco: Quantitative Analysis and Fate in Tobacco Combustion; Beitr. Tabakforsch. 8 (1975) 211–218.]Search in Google Scholar
[140. Schmeltz, I., D. Hoffmann, and J. Tosk: Naphthalenes in Tobacco Smoke: Analysis and Formation; presented at the 29th TCRC, College Park, MD, 1975, No. 22.]Search in Google Scholar
[141. Schmeltz, I., D. Hoffmann, and E. L. Wynder: The influence of tobacco smoke on indoor atmospheres. I. An overview; Prev. Med. 4 (1975) 66–82.]Search in Google Scholar
[142. Wynder, E. L. and D. Hoffmann: The tenth anniversary of the Surgeon General's report on smoking and health. Have we made any progress? Guest Editorial; J. Natl. Cancer Inst. 54 (1975) 533–534.]Search in Google Scholar
[143. Wynder, E. L., D. Hoffmann, P. Chan, and B. Reddy: Interdisciplinary and Experimental Approaches: Metabolic Epidemiology; in: Persons at High Risk of Cancer. An Approach to Cancer Etiology and Control; edited by J. F. Fraumeni, Academic Press, New York, NY, 1975, pp. 485–501.]Search in Google Scholar
[144. Brunnemann, K. D., S. S. Hecht, and D. Hoffmann: Analysis of N-Nitrosamines in Tobacco and Tobacco Smoke with the Aid of the Thermal Energy Analyzer; presented at the 30th TCRC, Nashville, TN, 1976, No. 38.]Search in Google Scholar
[145. Brunnemann, K. D. and D. Hoffmann: Analysis of Polynu-clear Aromatic Hydrocarbons in the Respiratory Environ-ment; in: Carcinogenesis - A Comprehensive Survey; edited by R. I. Freudenthal and P. W. Jones, Raven Press, New York, NY, 1976, pp. 283–297.]Search in Google Scholar
[146. Brunnemann, K. D., D. Hoffmann, E. L. Wynder, and G. B. Gori: Chemical Studies on Tobacco Smoke. XXXVII. Determination of tar, nicotine, and carbon monoxide in cigarette smoke. A comparison of international smoking conditions; in: Smoking and Health: I. Modifying the Risk for the Smoker. Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder et al., US Gov. Print. Off., Washington, DC, 1976, pp. 441–449.]Search in Google Scholar
[147. Brunnemann, K. D., H. C. Lee, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XLVII. On the quantitative analysis of catechols and their reduction; Anal. Lett. 9 (1976) 939–955.]Search in Google Scholar
[148. Brunnemann, K. D., L. Yu, and D. Hoffmann: Gas Chro-matographic Determination of Hydrogen Cyanide and Cyanogen in Tobacco Smoke; presented at the 30th TCRC, Nashville, TN, 1976, No. 36.]Search in Google Scholar
[149. Hecht, S. S., C. B. Chen, and D. Hoffmann: Synthesis of N-nitrosamino aldehydes; Tetrahedron Lett. 8 (1976) 593–596.10.1016/S0040-4039(00)77919-6]Search in Google Scholar
[150. Hecht, S. S., M. Loy, and D. Hoffmann: On the Structure and Carcinogenicity of the Methylchrysenes; in: Carcinogenesis - A Comprehensive Survey; edited by R. I. Freudenthal and P. W. Jones, Raven Press, New York, NY, 1976, pp. 325–340.]Search in Google Scholar
[151. Hecht, S. S., R. M. Ornaf, M. Dong, and D. Hoffmann: Studies on Nonvolatile Nitrosamines in Tobacco; presented at the 30th TCRC, Nashville, TN, 1976, No. 27.]Search in Google Scholar
[152. Hecht, S. S., I. Schmeltz, D. Hoffmann, and E. L. Wynder: Chemical Studies on Tobacco Smoke. XL. Identification of carcinogens in tobacco; in: Smoking and Health: I. Modifying the Risk for the Smoker. Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder, et al., US Gov. Print. Off., Washington, DC, 1976, pp. 191–202.]Search in Google Scholar
[153. Hecht, S. S., T. C. Tso, and D. Hoffmann: Selective Reduction of Tumorigenicity of Tobacco Smoke. IV. Approaches to the reduction of nitrosamines and aromatic amines; in: Smoking and Health: I. Modifying the Risk for the Smoker. Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder et al., US Gov. Print. Off., Washington, DC, 1976, pp. 535–545.]Search in Google Scholar
[154. Hoffmann, D., S. S. Hecht, K. D. Brunnemann, and E. L. Wynder: Analysis and formation of N-nitrosamines in tobacco and tobacco smoke; presented at the CORESTA Congress Tokyo, Japan, 1976, No. S017.]Search in Google Scholar
[155. Hoffmann, D., S. S. Hecht, R. M. Ornaf, E. L. Wynder, and T. C. Tso: Chemical Studies on Tobacco Smoke. XLII. Nitrosonornicotine: Presence in Tobacco, Formation and Carcinogenicity; in: Asbestos, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 14, 1976, pp. 307–320.]Search in Google Scholar
[156. Hoffmann, D., C. P. Patrianakos, K. D. Brunnemann, and G. B. Gori: Chemical Studies on Tobacco Smoke. XXXVI. Chromatographic determination of vinyl chloride in tobacco smoke; Anal. Chem. 48 (1976) 47–50.]Search in Google Scholar
[157. Hoffmann, D., I. Schmeltz, S. S. Hecht, and E. L. Wynder: Chemical Studies on Tobacco Smoke. XXXIX. On the identification of carcinogens, tumor promoters, and cocarcinogens in tobacco smoke; in: Smoking and Health: I. Modifying the Risk for the Smoker. Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder et al., US Gov. Print. Off., Washington, DC, 1976, pp. 125–145.]Search in Google Scholar
[158. Hoffmann, D. and E. L. Wynder: Environmental Respiratory Carcinogenesis; in: Chemical Carcinogenesis; edited by C. E. Searle, Am. Chem. Soc. Monograph No. 173, Washington, DC, 1976, pp. 324–365.]Search in Google Scholar
[159. Hoffmann, D. and E. L. Wynder: Selective reduction of tumorigenicity of tobacco smoke. III. The reduction of polynuclear aromatic hydrocarbons in cigarette smoke; in: Smoking and Health. I: Modifying the Risk for the Smoker. Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder et al., US Gov. Print. Off., Washington, DC, 1976, pp. 495–504.]Search in Google Scholar
[160. Hoffmann, D. and E. L. Wynder: Smoking and occupational cancers; Prev. Med. 5 (1976) 245–261.]Search in Google Scholar
[161. Schmeltz, I., K. D. Brunnemann, D. Hoffmann, and A. Cornell: [Chemical Studies on Tobacco Smoke. XLV.] On the chemistry of cigar smoke: Comparisons Between Experimental Little and Large Cigars; Beitr. Tabakforsch. 8 (1976) 367–377.]Search in Google Scholar
[162. Schmeltz, I. and D. Hoffmann: Chemical Studies on Tobacco Smoke. XXXVIII. The physicochemical nature of cigarette smoke; in: Smoking and Health: I. Modifying the Risk for the Smoker; Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder et al., US Gov. Print. Off., Washington, DC, 1976, pp. 13–34.]Search in Google Scholar
[163. Schmeltz, I. and D. Hoffmann: Formation of Polynuclear Aromatic Hydrocarbons from Combustion of Organic Matter; in: Carcinogenesis - Polynuclear Aromatic Hydro-carbons: Chemistry, Metabolism, and Carcinogenesis; edited by R. I. Freudenthal and P. W. Jones, Raven Press, New York, NY, 1976, pp. 225–239.]Search in Google Scholar
[164. Schmeltz, I., J. Tosk, and D. Hoffmann: Chemical Studies on Tobacco Smoke. XLVI. Formation and determination of naphthalenes in cigarette smoke; Anal. Chem. 48 (1976) 645–650.]Search in Google Scholar
[165. Schmeltz, I., J. Tosk, G. Jacobs, and D. Hoffmann: The Redox Potential and Quinone Content of Cigarette Smoke; presented at the 30th TCRC, Nashville, TN, 1976, No. 44.]Search in Google Scholar
[166. Schmeltz, I., A. Wenger, D. Hoffmann, and T. C. Tso: Use of Radioactive Tobacco Isolates for Studying the Formation of Selected Smoke Components; presented at the 30th TCRC, Nashville, TN, 1976, No. 35.]Search in Google Scholar
[167. Tso, T. C., G. B. Gori, and D. Hoffmann: Reduction of Nicotine and Tar in Tobacco and in Cigarettes Through Agricultural Techniques; in: Smoking and Health: I. Modi-fying the Risk for the Smoker; Proc. 3rd World Conf. on Smoking and Health; edited by E. L. Wynder et al., US Gov. Print. Off., Washington, DC, 1976, pp. 35–48.]Search in Google Scholar
[168. Wynder, E. L. and D. Hoffmann: Tobacco and tobacco smoke; Semin. Oncol. 3 (1976) 5–15.]Search in Google Scholar
[169. Wynder, E. L., D. Hoffmann, and G. B. Gori (Editors): Smoking and Health: I. Modifying the Risk for the Smoker; Proc. 3rd World Conf. on Smoking and Health 1975, US Gov. Print. Off., Washington, DC, 1976.]Search in Google Scholar
[170. Brunnemann, K. D., J. D. Adams, and D. Hoffmann: Nonvol-atile N-Nitrosamines: Analysis in Tobacco and Tobacco Smoke by HPLC-TEA; presented at the 31st TCRC, Greens-boro, NC, 1977, No. 52.]Search in Google Scholar
[171. Brunnemann, K. D., G. Stahnke, and D. Hoffmann: Volatile Pyridines: Quantitative Analysis in Main- and Sidestream Smoke of Cigarettes and Cigars; presented at the 31st TCRC, Greensboro, NC, 1977, No. 36.]Search in Google Scholar
[172. Brunnemann, K. D., L. Yu, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XVII.] Assessment of carcino-genic volatile N-nitrosamines in tobacco and in mainstream and sidestream smoke from cigarettes; Cancer Res. 37 (1977) 3218–3222.]Search in Google Scholar
[173. Brunnemann, K. D., L. Yu, and D. Hoffmann: Chemical studies on tobacco smoke. XLIX. Gas chromatographic determination of hydrogen cyanide and cyanogen in tobacco smoke; J. Anal. Toxicol. 1 (1977) 38–42.]Search in Google Scholar
[174. Dong, M., D. Hoffmann, D. C. Locke, and E. Ferrand: Short Communication: The occurrence of caffeine in the air of New York City; Atmos. Environ. 11 (1977) 651–653.]Search in Google Scholar
[175. Dong, M. W., D. C. Locke, and D. Hoffmann: Characterization of aza-arenes in the basic organic portion of suspended particulate matter; Environ. Sci. Technol. 11 (1977) 612–618.]Search in Google Scholar
[176. Dong, M., D. C. Locke, and D. Hoffmann: Separation of aza-arenes by high pressure liquid chromatography; J. Chroma-togr. Sci. 15 (1977) 32–35.]Search in Google Scholar
[177. Dong, M., I. Schmeltz, R. Jacobs, and D. Hoffmann: Aza-arenes in Tobacco Smoke; presented at the 31st TCRC, Greensboro, NC, 1977, No. 43.]Search in Google Scholar
[178. Hecht, S. S., S. Carmella, and D. Hoffmann: Hydroxyphenyl Alcohols in Tobacco and Tobacco Smoke; presented at the 31st TCRC, Greensboro, NC, 1977, No. 51.]Search in Google Scholar
[179. Hecht, S. S., C. B. Chen, M. Dong, R. M. Ornaf, D. Hoffmann, and T. C. Tso: Chemical Studies on Tobacco Smoke. LI. Studies on Non-volatile Nitrosamines in Tobacco. Beitr. Tabakforsch. 9 (1977) 1–6.]Search in Google Scholar
[180. Hecht, S. S., I. Schmeltz, and D. Hoffmann: Chemical Studies on Tobacco Smoke. LVIII. Nitrogenous compounds in cigarette smoke and their possible precursors; presented at the 31st TCRC, Greensboro, NC, 1977, No. 3; in: Rec. Adv. Tobacco Sci. 3 (1977) 59–93.]Search in Google Scholar
[181. Hilfrich, J., S. S. Hecht, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XV. Effects of N’-nitrosonor-nicotine and N’-nitrosoanabasine in Syrian golden hamsters; Cancer Lett. 2 (1977) 169–176.]Search in Google Scholar
[182. Hoffmann, D., M. Dong, and S. S. Hecht: Chemical Studies on Tobacco Smoke. LII. Origin in tobacco smoke of N’-nitrosonornicotine, a tobacco-specific carcinogen: Brief Communication; J. Natl. Cancer Inst. 58 (1977) 1841–1844.]Search in Google Scholar
[183. Hoffmann, D., S. S. Hecht, I. Schmeltz, and E. L. Wynder: Polynuclear aromatic hydrocarbons: Occurrence, formation and carcinogenicity; in: Proc. Symp. Structural Correlates of Carcinogenesis and Mutagenesis: A Guide to Testing Priorities, FDA, Annapolis, MD, 1977, pp. 120–128.]Search in Google Scholar
[184. Hoffmann, D. and E. L. Wynder: The less harmful cigarette: present and future; World Smoking Health 2 (1977) 30–34.]Search in Google Scholar
[185. Hoffmann, D. and E. L. Wynder: Organic Particulate Pollutants. Chemical Analysis and Bioassays for Carcinoge-nicity; in: Air Pollution; edited by A. C. Stern, Academic Press, New York, NY, 1977, pp. 361–455.]Search in Google Scholar
[186. Patrianakos, C., K. D. Brunnemann, and D. Hoffmann: Aromatic Amines in Cigarette Smoke; presented at the 31st TCRC, Greensboro, NC, 1977, No. 44.]Search in Google Scholar
[187. Schmeltz, I., S. Abidi, and D. Hoffmann: [Chemical studies on tobacco smoke. XLVIII.] Tumorigenic agents in un-burned proc essed tobacco: N-nitrosodiethanolamine and 1,1-dimethylhydrazine; Cancer Lett. 2 (1977) 125–131.]Search in Google Scholar
[188. Schmeltz, I. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. L.] Nitrogen-containing compounds in tobacco and tobacco smoke. Chem. Rev. 77 (1977) 295–311.]Search in Google Scholar
[189. Schmeltz, I., D. Hoffmann, and B. Toth: Hydrazines: Occurence, analysis and carcinogenic activity as related to structure; in: Proc. Symp. Structural Correlates of Carcinogenesis and Mutagenesis: A Guide to Testing Priorities, FDA, Annapolis, MD, 1977, pp. 172–178.]Search in Google Scholar
[190. Schmeltz, I., J. Tosk, G. Jacobs, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XXXV.] The redox potential and quinone content of cigarette smoke; Anal. Chem. 49 (1977) 1924–1929.]Search in Google Scholar
[191. Schmeltz, I., A. Wenger, D. Hoffmann, and T. C. Tso: Use of Radioactive Tracers to Determine Cigarette Smoke Components that Arise from Nicotine During Tobacco Combustion; presented at the 31st TCRC, Greensboro, NC, 1977, No. 17.]Search in Google Scholar
[192. Stellman, J. M. and D. Hoffmann: Occupational bladder cancer; Lancet 310 (1977) 563–564.]Search in Google Scholar
[193. Toth, B., L. Wallcave, K. Patil, I. Schmeltz, and D. Hoffmann: Induction of tumors in mice with the herbicide succinic acid 2,2-dimethylhydrazine; Cancer Res. 37 (1977) 3497–3500.]Search in Google Scholar
[194. Adams, J. D., K. D. Brunnemann, and D. Hoffmann: Determi-nation of Nitric Oxide in Unaged Smoke by GSC-TEA; presented at the 32nd TCRC, Montreal, Canada, 1978, No. 36.]Search in Google Scholar
[195. Brunnemann, K. D., J. D. Adams, D. P. S. Ho, and D. Hoffmann: The influence of tobacco smoke on indoor atmo-spheres. II. Volatile and tobacco specific nitrosamines in main- and sidestream smoke and their contribution to indoor pollution; in: Proc. 4th Joint Conf. on Sensing of Environ-mental Pollutants, Am. Chem. Soc., New Orleans, LA, 1978, pp. 876–880.]Search in Google Scholar
[196. Brunnemann, K. D. and D. Hoffmann: Chemical Studies on Tobacco Smoke. LIX. Analysis of volatile nitrosamines in tobacco smoke and polluted indoor environments; in: Environmental Aspec ts of N-Ni tr oso Compounds, IARC Sci. Publ. 19 (1978) 343–356.]Search in Google Scholar
[197. Brunnemann, K. D., G. Stahnke, and D. Hoffmann: Chemical Studies on Tobacco Smoke. LXI. Volatile pyridines: quantitative analysis in mainstream and sidestream smoke of cigarettes and cigars; Anal. Lett. A-11 (1978) 545–560.]Search in Google Scholar
[198. Carmella, S., S. S. Hecht, and D. Hoffmann: Subfractionation of the Weakly Acidic Fraction of Cigarette Smoke Conden-sate by Preparative High Pressure Liquid Chromatography; presented at the 32nd TCRC, Montreal, Canada, 1978, No. 42.]Search in Google Scholar
[199. Chen, C. B., S. S. Hecht, and D. Hoffmann: [A Study of Chemical Carcinogenesis. XI.] Metabolic -hydroxylation of the tobacco-specific carcinogen, N’-nitrosonornicotine; Cancer Res. 38 (1978) 3639–3645.]Search in Google Scholar
[200. Chen, C. B., S. S. Hecht, E. LaVoie, and D. Hoffmann: Denitrosation of Tobacco Specific Nitrosamines by -Hydroxylation: An Approach to Their Reduction in Tobacco; presented at the 32nd TCRC, Montreal, Canada, 1978, No. 48.]Search in Google Scholar
[201. Chen, C. B., G. D. McCoy, S. S. Hecht, D. Hoffmann, and E. L. Wynder: [A Study of Chemical Carcinogenesis. X.] High pressure liquid chromatographic assay for -hydroxylation of N-nitrosopyrrolidine by isolated rat liver microsomes; Cancer Res. 38 (1978) 3812–3816.]Search in Google Scholar
[202. Dong, M., I. Schmeltz, and D. Hoffmann: Purification of quinolines for bioassay by preparative high pressure liquid chromatography; J. Chromatogr. 150 (1978) 269–272.]Search in Google Scholar
[203. Dong, M., I. Schmeltz, E. Jacobs, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LV.] Aza-arenes in tobacco smoke; J. Anal. Toxicol. 2 (1978) 21–25.]Search in Google Scholar
[204. Dong, M., I. Schmeltz, E. LaVoie, and D. Hoffmann: Aza-arenes in the respiratory environment: analysis and assays for mutagenicity; in: Carcinogenesis - Polynuclear Aromatic Hydrocarbons, Vol. 3; edited by R. W. Jones and R. I. Freudenthal, Raven Press, New York, NY, 1978, pp. 97-108.]Search in Google Scholar
[205. Hecht, S. S., S. Carmella, and D. Hoffmann: Chemical Studies on Tobacco Smoke. LIV. Determination of hydroxybenzyl alcohols and hydroxyphenyl ethanols in tobacco and tobacco smoke; J. Anal. Toxicol. 2 (1978) 56-59.]Search in Google Scholar
[206. Hecht, S. S., C. B. Chen, N. Hirota, R. M. Ornaf, T. C. Tso, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XVI.] Tobacco-specific nitrosamines: Formation from nico-tine in vitro and during tobacco curing, and carcinogenicity in strain A mice; J. Natl. Cancer Inst. 60 (1978) 819-824.]Search in Google Scholar
[207. Hecht, S. S., C. B. Chen, and D. Hoffmann: [A Study of Chemical Carcinogenesis. VI.] Evidence for metabolic a-hydroxylation of N-nitrosopyrrolidine; Cancer Res. 38 (1978) 215-218.]Search in Google Scholar
[208. Hecht, S. S., C. B. Chen, EJ. LaVoie, and D. Hoffmann: Formation and metabolism of tobacco-specific N-nitros-amines in leaf; presented at the CORESTA Symposium Sofia, Bulgaria, 1978, No. S16.]Search in Google Scholar
[209. Hecht, S. S., C. B. Chen, R. M. Ornaf, D. Hoffmann, and T. C. Tso: Chemical Studies on Tobacco Smoke. LVI. Tobacco-specific nitrosamines: origins, carcinogenicity and metabolism; in: Environmental Aspects of N-Nitroso Compounds, IARC Sci. Publ. 19 (1978) 395–413.]Search in Google Scholar
[210. Hecht, S. S., C. B. Chen, R. M. Ornaf, E. Jacobs, J. D. Adams, and D. Hoffmann: Chemical Studies on Tobacco Smoke. LII. Reaction of nicotine and sodium nitrite: Formation of nitrosamines and fragmentation of the pyrrolidine ring; J. Org. Chem. 43 (1978) 72-76.]Search in Google Scholar
[211. Hecht, S. S., N. Hirota, and D. Hoffmann: [A Study of Chemical Carcinogenesis. XII.] Comparative tumor initiating activity of 10-methylbenzo(a)pyrene, 7,10-dimethyl-benzo(a)pyrene, and benzo(a)pyrene; Cancer Lett. 5 (1978) 179-183.]Search in Google Scholar
[212. Hecht, S. S., N. Hirota, M. Loy, and D. Hoffmann: [A Study of Chemical Carcinogenesis. VIII.] Tumor initiating activity of fluorinated 5-methylchrysenes; Cancer Res. 38 (1978): 1694-1698.]Search in Google Scholar
[213. Hecht, S. S., E. LaVoie, R. Mazzarese, S. Amin, V. Bedenko, and D. Hoffmann: [A Study of Chemical Carcinogenesis. IX.] 1,2-Dihydro-1,2-dihydroxy-5-methylchrysene, a major activated metabolite of the environmental carcinogen, 5-methylchrysene; Cancer Res. 38 (1978) 2191-2194.]Search in Google Scholar
[214. Hecht, S. S., M. Loy, R. Mazzarese, and D. Hoffmann: A Study of Chemical Carcinogenesis. V. On the Carcinogenicity of 5-Methylchrysene: Structure-activity Studies and Metabolism; in: Polynuclear Aromatic Hydrocarbons and Cancer; edited by H. V. Gelboin and P. O. Ts'o, Academic Press, New York, NY, 1978, pp. 119-130.]Search in Google Scholar
[215. Hecht, S. S., M. Loy, R. Mazzarese, and D. Hoffmann: A Study of Chemical Carcinogenesis. VII. Synthesis and mutagenicity of modified chrysenes related to the carcinogen, 5-methylchrysene; J. Med. Chem. 21 (1978) 38–44.]Search in Google Scholar
[216. Hilfrich, J., I. Schmeltz, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XVII.] Effects of N-nitroso-diethanolamine and 1,1-diethanolhydrazine in Syrian golden hamsters; Cancer Lett. 4 (1978) 55-60.]Search in Google Scholar
[217. Hoffmann, D., K. D. Brunnemann, and J. Adams: Analysis of selected components in the smoke of little cigars; presented at the CORESTA Symposium Sofia, Bulgaria, 1978, No. S12.]Search in Google Scholar
[218. Hoffmann, D., I. Schmeltz, S. S. Hecht, K. D. Brunnemann, and E. L. Wynder: Volatile Carcinogens: Occurrence, Formation and Analysis; in: Prevention and Detection of Cancer, Part I: Prevention; edited by H. E. Nieburgs, Marcel Dekker, New York, NY, 1978, pp. 1943-1959.]Search in Google Scholar
[219. Hoffmann, D., I. Schmeltz, S. S. Hecht, and E. L. Wynder: Tobacco Carcinogenesis; in: Polycyclic Hydrocarbons and Cancer, Vol. 1: Chemistry; edited by H. V. Gelboin and P. O. Ts'o, Academic Press, New York, NY, 1978, pp. 85–117.]Search in Google Scholar
[220. Hoffmann, D. and E. L. Wynder: Identification and reduction of carcinogens in the respiratory environment; Zentralbl. Bakteriol. Parasitenkd. Infektionskr. Hyg. Orig. B, 166 (1978) 113–135.]Search in Google Scholar
[221. Schmeltz, I., K. D. Brunnemann, and D. Hoffmann: Analyti-cal Methods for Polynuclear Hydrocarbons, in: Prevention and Detection of Cancer, Part I: Prevention; edited by H. E. Nieburgs, Marcel Dekker, New York, NY, 1978, pp. 1973–1992.]Search in Google Scholar
[222. Schmeltz, I., K. G. Chiong, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LX.] Formation and determination of ethyl carbamate in tobacco and tobacco smoke; J. Anal. Toxicol. 2 (1978) 265–268.]Search in Google Scholar
[223. Schmeltz, I., J. Tosk, H. Hilfrich, N. Hirota, D. Hoffmann, and E. L Wynder: Bioassays of Naphthalene and Alkyl-naphthalene for Co-carcinogenic Activity. Relation to Tobacco Carcinogenesis; in: Carcinogenesis - A Compre-hensive Survey; edited by R. W. Jones and R. I. Freudenthal, Raven Press, New York, NY, 1978, pp. 47–60.]Search in Google Scholar
[224. Schmeltz, I., A. Wenger, D. Hoffmann, and T. C. Tso: Chemical Studies on Tobacco Smoke. LIII. Use of radioactive tobacco isolates for studying the formation of smoke components; J. Agr. Food Chem. 26 (1978) 234–239.]Search in Google Scholar
[225. Weiss, L., M. Loy, S. S. Hecht, and D. Hoffmann: A Study of Chemical Carcinogenesis. IV. Synthesis of the carbon-14 labelled carcinogens 5-methylchrysene, 2-methylaniline, and 3-methyl-2-naphthylamine; J. Labelled Compd. Radio-pharm. 14 (1978) 119–131.]Search in Google Scholar
[226. Wynder, E. L., D. Hoffmann, G. D. McCoy, L. A. Cohen, and B. S. Reddy: Tumor Promotion and Cocarcinogenesis as Related to Man and His Environment; in: Carcinogenesis, Vol. 2: Mechanisms of Tumor Promotion and Cocarcinoge-nesis; edited by J. Slaga et al., Raven Press, New York, NY, 1978 pp. 59–77.]Search in Google Scholar
[227. Amin, S., S. S. Hecht, E. LaVoie, and D. Hoffmann: A Study of Chemical Carcinogenesis. XIX. Synthesis and mutageni-city of 5,11-dimethylchrysene and some methyl-oxidized derivatives of 5-methylchrysene; J. Med. Chem. 22 (1979) 1336–1340.]Search in Google Scholar
[228. Carmella, S., S. S. Hecht, and D. Hoffmann: Quantitative Analysis of Alkyl-2-hydroxy-2-cyclopentene-1-ones in Tobacco Smoke; presented at the 33rd TCRC, Lexington, KY, 1979, No. 54.]Search in Google Scholar
[229. DeVera, N., I. Schmeltz, S. S. Hecht, and D. Hoffmann: Moderately polar non-PAH neutral components in cigarette smoke; presented at the 33rd TCRC, Lexington, KY, 1979, No. 49.]Search in Google Scholar
[230. Hecht, S. S., S. Amin, A. Rivenson, and D. Hoffmann: A Study of Chemical Carcinogenesis. XX. Tumor initiating activity of 5,11-dimethylchrysene, 5,12-dimethylchrysene and 5-methylchrysene; Cancer Lett. 8 (1979) 65–70.]Search in Google Scholar
[231. Hecht, S. S., C. B. Chen, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XVII. Tobacco-specific nitros-amines: Occurrence, formation, carcinogenicity, and metabolism; Acc. Chem. Res. 12 (1979) 92–98.]Search in Google Scholar
[232. Hecht, S. S., C. B. Chen, G. D. McCoy, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XVIII. Tobacco-specific nitrosamines: Occurrence, carcinogenicity, and metabolism; in: Proceedings 8th Northeastern Regional Meeting, Am. Chem. Soc. Symp. Ser. 101 (1979) 125–152.]Search in Google Scholar
[233. Hecht, S. S., C. B. Chen, G. D. McCoy, D. Hoffmann, and L. A. Domellöf: [A Study of Chemical Carcinogenesis. XVIII.] -Hydroxylation of N-nitrosopyrrolidine and N’-nitrosonornicotine by human liver microsomes; Cancer Lett. 8 (1979) 35–41.]Search in Google Scholar
[234. Hecht, S. S., E. LaVoie, and D. Hoffmann: A Study of Chemical Carcinogenesis. XIII. Structure-activity relation-ships in polynuclear aromatic hydrocarbons; in: Proc. Lawrence Berkeley Lab. Conf. on Carbonaceous Particles in the Atmosphere; edited by T. Novakov, Natl. Techn. Inform. Serv., US Dept. Commerce, Springfield, VA, 1979, pp. 177-186.]Search in Google Scholar
[235. Hecht, S. S., E. LaVoie, R. Mazzarese, N. Hirota, T. Ohmori, and D. Hoffmann: [A Study of Chemical Carcinogenesis. XVI.] Comparative mutagenicity, tumor-initiating activity, carcinogenicity, and in vitro metabolism of fluorinated 5-methylchrysenes; J. Natl. Cancer Inst. 63 (1979) 855-861.]Search in Google Scholar
[236. Hecht, S. S., R. Mazzarese, S. Amin, EJ. LaVoie, and D. Hoffmann: A Study of Chemical Carcinogenesis. XV. On the Metabolic Activation of 5-Methylchrysene; in: Polynu-clear Aromatic Hydrocarbons; edited by P. W. Jones and P. Leber, Ann Arbor Sci. Publ., Ann Arbor, MI, 1979, pp. 733-752.]Search in Google Scholar
[237. Hoffmann, D., J. D. Adams, K. D. Brunnemann, and S. S. Hecht: [Chemical Studies on Tobacco Smoke. LXII.] Assessment of tobacco-specific N-nitrosamines in tobacco products; Cancer Res. 39 (1979) 2505-2509.]Search in Google Scholar
[238. Hoffmann, D., J. D. Adams, and E. L. Wynder: [Chemical Studies on Tobacco Smoke. LXV.] Formation and analysis of carbon monoxide in cigarette mainstream and sidestream smoke; Prev. Med. 8 (1979) 344-350.]Search in Google Scholar
[239. Hoffmann, D., K. D. Brunnemann, I. Schmeltz, and E. L. Wynder: Trace Analysis in Respiratory carcinogenesis; in: Trace Organic Analysis: A New Frontier in Analytical Chemistry; edited by H. S. Hertz and S. N. Chester, Natl. Bureau of Standards Special Publ. No. 519, US Govt. Print. Off, Washington, DC, 1979, pp. 131-141.]Search in Google Scholar
[240. Hoffmann, D., A. Rivenson, S. S. Hecht, J. Hilfrich, N. Kobayashi, and E. L. Wynder: Model studies in tobacco carcinogenesis with the Syrian golden hamster; Progr. Exp. Tumor Res. 24 (1979) 370-390.]Search in Google Scholar
[241. LaVoie, E., V. Bedenko, N. Hirota, S. S. Hecht, and D. Hoffmann: A Comparison of the Mutagenicity, Tumor-initiating Activity and Complete Carcinogenicity of Polynu-clear Aromatic Hydrocarbons; in: Polynuclear Aromatic Hydrocarbons; edited by P. W. Jones and P. Leber, Ann Arbor Sci. Publ., Ann Arbor, MI, 1979, pp. 705-721.]Search in Google Scholar
[242. LaVoie, E., L. Tulley, E. Fow, and D. Hoffmann: Mutagenicity of aminophenyl and nitrophenyl ethers, sulfides, and disulfides; Mutat. Res. 67 (1979) 123-131.]Search in Google Scholar
[243. Patrianakos, C. and D. Hoffmann: Chemical Studies on Tobacco Smoke. LXIV. On the analysis of aromatic amines in cigarette smoke; J. Anal. Toxicol. 3 (1979) 150-154.]Search in Google Scholar
[244. Piade, J. J, J. D. Adams, and D. Hoffmann: Alkaloids and Nonvolatile N-Nitrosamines in Tobacco and Smoke of French Cigarettes; presented at the 33rd TCRC, Lexington, KY, 1979, No. 56.]Search in Google Scholar
[245. Schmeltz, I., K. D. Brunnemann, and D. Hoffmann: Trace analysis in agricultural products: methods for hydrazines, carbamates, N-nitrosodiethanolamine and other compounds; in: Trace Organic Analysis: A New Frontier in Analytical Chemistry; edited by H. S. Hertz and S. N. Chester, Natl. Bureau of Standards Special Publ. No. 519, U. S. Govt. Print. Off, Washington, DC, 1979, pp. 297-309.]Search in Google Scholar
[246. Schmeltz, I., A. Wenger, D. Hoffmann, and T. C. Tso: Chemical Studies on Tobacco Smoke. LXIII. On the fate of nicotine during py roly sis and in a burning cigarette; J. Agric. Food Chem. 27 (1979) 602-608.]Search in Google Scholar
[247. Tosk, J., I. Schmeltz, and D. Hoffmann: Hydrazines as mutagens in a histidine-requiring auxotroph of Salmonella typhimurium; Mutat. Res. 66 (1979) 247-252.]Search in Google Scholar
[248. Wynder, E. L. and D. Hoffmann: Rauchen und Gesundheit. Die Epidemiologie tabakbedingter Erkrankungen; Therapiewoche 29 (1979) 8747-8757.]Search in Google Scholar
[249. Wynder, E. L. and D. Hoffmann: Perforated filter-tip cigarettes: effect on tar, nicotine, and carbon monoxide intake; JAMA 241 (1979) 295.]Search in Google Scholar
[250. Wynder, E. L. and D. Hoffmann: Stopping smoking (Letter); New Engl. J. Med. 301 (1979) 390.]Search in Google Scholar
[251. Wynder, E. L. and D. Hoffmann: Smoking and Health: Pathogenic and Preventive Considerations; Bull. Schweiz. Akad. Med. Wiss. 35 (1979) 83–98.]Search in Google Scholar
[252. Wynder, E. L. and D. Hoffmann: Tobacco and Health. A societal challenge; New Engl. J. Med. 300 (1979) 894–903.]Search in Google Scholar
[253. Adams, J. D., J. J. Piade, and D. Hoffmann: The selective reduction of tobacco specific N-nitrosamines from cigarette smoke; presented at the 34th TCRC, Richmond, VA, 1980, No. 50.]Search in Google Scholar
[254. Brunnemann, K. D., D. Hoffmann, and T. C. Tso: The fate of diethanolamine in tobacco and cigarette smoke; presented at the 34th TCRC, Richmond, VA, 1980, No. 51.]Search in Google Scholar
[255. Carmella, S., S. S. Hecht, D. Hoffmann, and T. C. Tso: The formation of catechol in cigarette smoke; presented at the 34th TCRC, Richmond, VA, 1980, No. 30.]Search in Google Scholar
[256. Chen, C. B., S. S. Hecht, G. D. McCoy, and D. Hoffmann: Assays for metabolic -hydroxylation of N’-nitrosonornico-tine and N-nitrosopy rrolidine and the influence of modifying factors; in: N-Nitroso Compounds: Analysis, Formation and Occurrence, IARC Sci. Publ. 31 (1980) 349–359.]Search in Google Scholar
[257. Hecht, S. S., C. B. Chen, and D. Hoffmann: [A Study of Chemical Carcinogenesis. XXIX.] Metabolic -hydroxylation and N-oxidation of N’-nitrosonornicotine; J. Med. Chem. 23 (1980) 1175–1178.]Search in Google Scholar
[258. Hecht, S. S., C. B. Chen, T. Ohmori, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XIX.] Comparative car-cinogenicity in F344 rats of the tobacco-specific nitros-amines, N’-nitrosonornicotine and 4-(N-methyl-N-nitros-amino)-1-(3-pyridyl)-1-butanone; Cancer Res. 40 (1980) 298–302.]Search in Google Scholar
[259. Hecht, S. S., C. B. Chen, R. Young, D. Lin, and D. Hoffmann: Metabolism of the tobacco-specific nitrosamines, N’-nitrosonornicotine and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone, in: N-Nitroso Compounds: Analysis, Formation and Occurrence, IARC Sci. Publ. 31 (1980) 755–765.]Search in Google Scholar
[260. Hecht, S. S., E. LaVoie, S. Amin, V. Bedenko, and D. Hoffmann: On the metabolic activation of the benzofluor-anthenes, in: Polynuclear Aromatic Hydrcarbons: Chemistry and Biological Effects; edited by A. Bjorseth and A. J. Dennis, Battelle Press, Columbus, OH, 1980, pp. 417–433.]Search in Google Scholar
[261. Hecht, S. S., A. Rivenson, and D. Hoffmann: Tumor-initiating activity of dihydrodiols formed metabolically from 5-methylchrysene; Cancer Res. 40 (1980) 1396–1399.]Search in Google Scholar
[262. Hoffmann, D., J. D. Adams, J. J. Piade, and S. S. Hecht: Chemical Studies on Tobacco Smoke. LXVIII. Analysis of volatile and tobacco-specific nitrosamines in tobacco products; in: N-Nitroso Compounds: Analysis, Formation and Occurrence, IARC Sci. Publ. 31 (1980) 507–516.]Search in Google Scholar
[263. Hoffmann, D., C. B. Chen, and S. S. Hecht: The role of volatile and nonvolatile N-nitrosamines in tobacco carcino-genesis; in: Banbury Report 3: A Safe Cigarette?; edited by G. B. Gori and F. B. Bock, Cold Spring Harbor Laboratory Publ., Cold Spring Harbor, NY, 1980, pp. 113–127.]Search in Google Scholar
[264. Hoffmann, D., S. S. Hecht, and E. L. Wynder: The role of polynuclear aromatic hydrocarbons in tobacco carcinogene-sis; presented at the Polycyclic Aromatic Hydrocarbons Conf. of the Verein Deutscher Ingenieure, Hannover, Germany, 1979; VDI-Ber. 358 (1980) 335–350.]Search in Google Scholar
[265. Hoffmann, D. and I. Hoffmann: Oncology Overview on Organ Specific Carcinogenicity of Tobacco Products. 1. Epidemiology of Non-Respiratory Tract Cancer and Related Clinical Observations; Internatl. Cancer Res. Data Bank PB80-922907, US Dept. H. H. S., 1980.]Search in Google Scholar
[266. Hoffmann, D., T. C. Tso, and G. B. Gori: The Less Harmful Cigarette; Prev. Med. 9 (1980) 287–296.]Search in Google Scholar
[267. Hoffmann, D. and E. L. Wynder: The low yield cigarette. Editorial; Am. J. Public Health, 70 (1980) 1143–1144; Response to Letter to the Editor; Am. J. Public Health, 71 (1981) 536–537.]Search in Google Scholar
[268. LaVoie, E. J., S. S. Hecht, S. Amin, V. Bedenko, and D. Hoffmann: Identification of mutagenic dihydrodiols as metabolites of benzo(j)fluoranthene and benzo(k)fluoran-thene; Cancer Res. 40 (1980) 4528–4532.]Search in Google Scholar
[269. LaVoie, E. J., S. S. Hecht, D. Hoffmann, and E. L. Wynder: The less harmful cigarette and tobacco smoke flavors; Banbury Report 3: A Safe Cigarette?; edited by G. B. Gori and F. B. Bock, Cold Spring Harbor Laboratory Publ., Cold Spring Harbor, NY, 1980, pp. 251–260.]Search in Google Scholar
[270. LaVoie, E., L. Tulley, V. Bedenko, and D. Hoffmann: Mutagenicity, tumor initiating activity and metabolism of tricyclic polynuclear aromatic hydrocarbons; in: Polynuclear Aromatic Hydrocarbons: Chemistry and Biological Effects.; edited by A. Bjorseth and A. J. Dennis, Battelle Press, Columbus, OH, 1980, pp. 1041–1057.]Search in Google Scholar
[271. Piade, J. J., J. D. Adams, and D. Hoffmann: The semi-volatile and gasphases of cigarette smoke from air cured tobacco: chromatographic profiling and effect of aging; presented at the 34th TCRC, Richmond, VA, 1980, No. 16.]Search in Google Scholar
[272. Piade, J. J. and D. Hoffmann: Chemical Studies on Tobacco Smoke. LXVII. Quantitative determination of alkaloids in tobacco by liquid chromatography; J. Liq. Chromatogr. 3 (1980) 1505–1515.]Search in Google Scholar
[273. Rivenson, A., T. Ohmori, S. S. Hecht, and D. Hoffmann: Organotropic carcinogenicity of tobacco-specific N-nitros-amines, in: Biology of the Cancer Cell; edited by K. Letnan-sky, Kugler Publ., Amsterdam, The Netherlands, 1980, pp. 51–62.]Search in Google Scholar
[274. Rühl, C., J. D. Adams, and D. Hoffmann: Chemical Studies on Tobacco Smoke. LXVI. Comparative assessment of volatile and tobacco-specific N-nitrosamines in the smoke of selected cigarettes from the USA, West Germany and France; J. Anal. Toxicol. 4 (1980) 255–259.]Search in Google Scholar
[275. Schmeltz, I., K. D. Brunnemann, and D. Hoffmann: Aza-arenes and other nitrogen-containing compounds in the respiratory environment. Proc. Am. Inst. Chem. Engineers Symposium Ser. 196, 1980, pp. 312–320.]Search in Google Scholar
[276. Schmeltz, I., A. Wenger, and D. Hoffmann: TLC in the Analysis of the Respiratory Environment; in: Thin-layer Chromatography: Quantitative, Environmental, and Clinical Applications; edited by J. C. Touchstone and D. Rogers, J. Wiley and Sons, New York, NY, 1980, pp. 325–347.]Search in Google Scholar
[277. Adams, J. D., A. Castonguay, S. J. Lee, N. Vinchkoski, and D. Hoffmann: Formation and Transfer of 4-(Methylnitros-amino)-1-(3-pyridyl)-butanone (NNK) During Smoking; pres. at the 35th TCRC, Winston-Salem, NC, 1981, No. 49.]Search in Google Scholar
[278. Amin, S., V. Bedenko, E. LaVoie, S. S. Hecht, and D. Hoffmann: Study of chemical carcinogenesis. XXII. Syn-thesis of dihydrodiols as potential proximate carcinogens of benzofluoranthenes; J. Org. Chem. 46 (1981) 2573–2578.]Search in Google Scholar
[279. Amin, S., S. S. Hecht, and D. Hoffmann: Synthesis of angular ring methoxy-5-methylchrysenes and 5-methyl-chrysenols; J. Org. Chem. 46 (1981) 2394–2398.]Search in Google Scholar
[280. Brunnemann, K. D. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXIX.] Assessment of the carcinogenic N-nitrosodiethanolamine in tobacco products and tobacco smoke; Carcinogenesis 2 (1981) 1123–1127.]Search in Google Scholar
[281. Brunnemann, K. D. and D. Hoffmann: Concurrent Gas Chromatographic Determination of Volatile, Nonvolatile, and Tobacco Specific N-Nitrosamines; presented at the 35th TCRC, Winston-Salem, NC, 1981, No. 33.]Search in Google Scholar
[282. Carmella, S., S. S. Hecht, and D. Hoffmann: Precursor Studies on Catechol in Cigarette Smoke; presented at the 35th TCRC, Winston-Salem, NC, 1981, No. 50.]Search in Google Scholar
[283. El-Bayoumy, K., E. J. LaVoie, S. S. Hecht, E. A. Fow, and D. Hoffmann: The influence of methyl substitution on the mutagenicity of nitronaphthalenes and nitrobiphenols; Mutat. Res. 81 (1981) 143–153.]Search in Google Scholar
[284. Hecht, S. S., S. Carmella, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXX.] Quantitative Analysis of Alkyl-2-hydroxy-2-cyclopenten-1-ones in Tobacco Smoke; J. Agric. Food Chem. 29 (1981) 401–404.]Search in Google Scholar
[285. Hecht, S. S., S. Carmella, H. Mori, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XX. Role of Catechol as a Major Cocarcinogen in the Weakly Acidic Fraction of Smoke Condensate; J. Natl. Cancer Inst. 66 (1981) 163–169.]Search in Google Scholar
[286. Hecht, S. S., C. B. Chen, R. Young, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXI.] Mass Spectra of Tobacco-specific Nitrosamines, Their Metabolites, and Related Compounds; Beitr. Tabakforsch. Int. 11 (1981) 57–66.]Search in Google Scholar
[287. Hecht, S. S., E. J. LaVoie, V. Bedenko, D. Hoffmann, D. J. Sardella, E. Boger, and R. Lehr: A Study of Chemical Carcinogenesis. XXXII. On the Metabolic Activation of Dibenzo[a, i]pyrene and Dibenzo[a, h]pyrene; in: Polynuclear Aromatic Hydrocarbons: Chemical Analysis and Biological Fate; edited by M. Cooke and A. J. Dennis, Battelle Press, Columbus, OH, 1981, pp. 43–54.]Search in Google Scholar
[288. Hecht, S. S., E. J. LaVoie, V. Bedenko, L. Pingaro, S. Katayama, D. Hoffmann, D. J. Sardella, E. Boger, and R. E. Lehr: Reduction of tumorigenicity and of dihydrodiol formation by fluorine substitution in the angular rings of dibenzo[a, i]pyrene; Cancer Res. 41 (1981) 4341–4345.]Search in Google Scholar
[289. Hoffmann, D. and J. D. Adams: [A Study of Tobacco Carcinogenesis. XXIII.] Carcinogenic tobacco-specific N-nitrosamines in snuff and in the saliva of snuff dippers; Cancer Res. 41 (1981) 4305–4308.]Search in Google Scholar
[290. Hoffmann, D., J. D. Adams, K. D. Brunnemann, and S. S. Hecht: Formation, occurrence and carcinogenicity of N-nitrosamines in tobacco products; in: N-Nitroso Compounds; edited by R. A. Scanlan and S. R. Tannenbaum, Am. Chem. Soc. Symp. Ser. 174, Washington, DC, 1981, pp. 247–273.10.1021/bk-1981-0174.ch018]Search in Google Scholar
[291. Hoffmann, D., A. Castonguay, A. Rivenson, and S. S. Hecht: [A Study of Tobacco Carcinogenesis. XXII.] Comparative carcinogenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N’-nitrosonornicotine in Syrian golden hamsters; Cancer Res. 41 (1981) 2386–2393.]Search in Google Scholar
[292. Hoffmann, D. and I. Hoffmann: Oncology overview on organ specific carcinogenicity of tobacco products. 2. Bioassays, physicochemical analysis, and other experimental evidence; Internatl. Cancer Res. Data Bank PB81-922902, US Dept. H. H. S., 1981.]Search in Google Scholar
[293. LaVoie, E. J., A. Govil, G. Briggs, and D. Hoffmann: Mutagenicity of aminocarbazoles and nitrocarbazoles; Mutat. Res. 90 (1981) 337–344.10.1016/0165-1218(81)90056-2]Search in Google Scholar
[294. LaVoie, E. J., A. Rivenson, B. Bedenko, E. Kolb, T. Ohmori, and D. Hoffmann: Carcinogenicity in Syrian golden ham-sters of N-nitrosamines formed during nitrosation of spermi-dine; Cancer Detect. Prev. 4 (1981) 79–84.]Search in Google Scholar
[295. LaVoie, E. J., L. Tulley-Freiler, V. Bedenko, and D. Hoffmann: On the metabolic activation of methylated phenan-threnes; presented at the 72nd Ann. Meeting Am. Assoc. Cancer Res., 1981, No. 370.]Search in Google Scholar
[296. LaVoie, E. J., L. Tulley, V. Bedenko, and D. Hoffmann: Mutagenicity and methylated fluorenes and benzofluorenes; Mutat. Res. 91 (1981) 167–176.10.1016/0165-7992(81)90027-0]Search in Google Scholar
[297. LaVoie, E. J., L. Tulley-Freiler, V. Bedenko, Z. Girach, and D. Hoffmann: Comparative Studies on the Tumor-initiating Activity and Metabolism of Methylfluorenes and Methyl-benzofluorenes; in: Polynuclear Aromatic Hydrocarbons: Chemical Analysis and Biological Fate; edited by M. Cooke and A. J. Dennis, Battelle Press, Columbus, OH, 1981, pp. 417–427.]Search in Google Scholar
[298. LaVoie, E. J., L. Tulley-Freiler, V. Bedenko, and D. Hoff mann: Mutagenicity, tumor initiating activity and metabolism of methylphenanthrenes; Cancer Res. 41 (1981) 3441-3447.]Search in Google Scholar
[299. Melikian, A., EJ. LaVoie, D. Hoffmann, and E. L. Wynder: Volatile nitrosamines: analysis in breast fluid and blood of non-lactating women; Food Cosmet. Toxicol. 19 (1981) 757-759.]Search in Google Scholar
[300. Adams, J. D., K. D. Brunnemann, S. S. Hecht, and D. Hoffmann: Biogenesis and chemistry of alkaloid-derived N-nitrosamines; presented at the 184th Natl. Mtg., Am. Chem. Soc, 1982, No. 66.]Search in Google Scholar
[301. Adams, J. D., EJ. LaVoie, and D. Hoffmann: Analysis of methy lated polynuclear aromatic hy drocarbons by capillary gas chromatography. Influence of temperature on the pyro-synthesis of anthracene, phenanthrene, and their methy lated derivatives; J. Chromatogr. Sci. 20 (1982) 274-277.]Search in Google Scholar
[302. Adams, J. D., A. Shigematsu, P. Owens, EJ. LaVoie, and D. Hoffmann: Quinolines and methylquinolines in the main-stream smoke of commercial cigarettes; presented at the 36th TCRC, Raleigh, NC, 1982, No. 38.]Search in Google Scholar
[303. Brunnemann, K. D., S. S. Hecht, and D. Hoffmann: N-Nitrosamines: Environmental occurrence, in vivo formation and metabolism; J. Toxicol. Clin. Toxicol. 19 (1982) 661-688.]Search in Google Scholar
[304. Brunnemann, K. D. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXIV.] Pyrolytic origins of major gas phase constituents of cigarette smoke; presented at the 36th TCRC, Raleigh, NC, 1982, No. 3; in: Rec. Adv. Tobacco Sci. 8 (1982) 103-140.]Search in Google Scholar
[305. Brunnemann, K. D., J. C. Scott, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXII.] N-Nitrosomorpholine and other volatile N-nitrosamines in snuff tobacco; Carcinogenesis 3 (1982) 693-696.]Search in Google Scholar
[306. Carmella, S., S. S. Hecht, D. Hoffmann, and T. C. Tso: Cellulose and modified cellulose as precursors to catechol in cigarette smoke; presented at the 36th TCRC, Raleigh, NC, 1982, No. 39.]Search in Google Scholar
[307. Castonguay, A., S. S. Hecht, D. Hoffmann, G. D. Stoner, and H. AJ. Schut: Metabolism of tobacco-specific nitrosamines in cultured human tissues; presented at the 73rd Ann. Meeting Am. Assoc. Cancer Res., 1982, No. 333.]Search in Google Scholar
[308. El-Bayoumy, K., S. S. Hecht, and D. Hoffmann: [A Study of Chemical Carcinogenesis. XLVI.] Comparative tumor initiating activity on mouse skin of 6-nitrobenzo[a]pyrene, 6-nitrochrysene, 3-nitropyrene, 1-nitropyrene and their parent hy drocarbons; Cancer Lett. 16 (1982) 333-337.]Search in Google Scholar
[309. Gutenmann, W. H., CA. Bache, DJ. Lisk, D. Hoffmann, J. D. Adams, and D. C. Elfving: Cadmium and nickel in smoke of cigarettes prepared from tobacco cultured on municipal sludge-amended soil; J. Toxicol. Environ. Health 10 (1982) 423–431.]Search in Google Scholar
[310. Hecht, S. S., A. Castonguay, F. -L. Chung, D. Hoffmann, and G. D. Stoner: Recent studies on the metabolic activation of cyclic nitrosamines; in: Banbury Report 12: Nitrosamines and Human Cancer; edited by P. N. Magee, Cold Spring Harbor Laboratory Publ., Cold Spring Harbor, NY, 1982, pp. 103-120.]Search in Google Scholar
[311. Hecht, S. S., G. D. McCoy, B. C. Chen, and D. Hoffmann: The metabolism of cyclic nitrosamines; in: N-Nitroso Compounds; edited by RA. Scanlan and S. R. Tannenbaum, Am. Chem. Soc. Symp. Ser. 174, Washington, DC, 1982, pp. 49-75.10.1021/bk-1981-0174.ch004]Search in Google Scholar
[312. Hecht, S. S., R. Young, A. Rivenson, and D. Hoffmann: On the metabolic activation of N-nitrosomorpholine and N’-nitrosonornicotine: effects of deuterium substitution; in: N-Nitroso Compounds: Occurrence and Biological Effects, IARC Sci. Publ. 41 (1982) 499-507.]Search in Google Scholar
[313. Hoffmann, D., J. D. Adams, A. Rivenson, and S. S. Hecht: Alkaloid-derived N-nitrosamines, a major group of tobacco carcinogens; presented at the 13th International Cancer Congress, Seattle, 1982, No. 2292.]Search in Google Scholar
[314. Hoffmann, D., J. D. Adams, K. D. Brunnemann, A. Rivenson, and S. S. Hecht: Tobacco-specific N-Nitrosamines: Occur-rence and Bioassays; in: N-Nitroso Compounds: Occurrence and Biological Effects, IARC Sci. Publ. 41 (1982) 309–318.]Search in Google Scholar
[315. Hoffmann, D., J. D. Adams, N. Vinchkoski, and T. C. Tso: On the fate of nicotine-14C during leaf curing and smoking; presented at the CORESTA Symposium Winston-Salem, NC, 1982, No. S04.]Search in Google Scholar
[316. Hoffmann, D., K. D. Brunnemann, J. D. Adams, A. Rivenson, and S. S. Hecht: N-Nitrosamines in tobacco carcinogenesis; in: Banbury Report 12: Nitrosamines and Human Cancer; edited by P. N. Magee, Cold Spring Harbor Laboratory Publ., Cold Spring Harbor, NY, 1982, pp. 211–225.]Search in Google Scholar
[317. Hoffmann, D., K. D. Brunnemann, A. Rivenson, and S. S. Hecht: N-Nitrosodiethanolamine: Analysis, formation in tobacco products and carcinogenicity in Syrian golden hamsters; presented at the 7th International Meeting on N-Nitroso Compounds, Tokyo, Japan, 1981; in: N-Nitroso Compounds: Occurrence and Biological Effects, IARC Sci. Publ. 41 (1982) 299–307.]Search in Google Scholar
[318. Hoffmann, D. and I. Hoffmann: Experimental Carcinogene-sis with Tobacco Products; in: Health Consequences of Smoking - Cancer. A Report of the Surgeon General, Part III, US Department of Health and Human Services, Washington, DC, DHHS (PHS) 82–50179, 1982, pp. 181–235.]Search in Google Scholar
[319. Hoffmann, D., E. J. LaVoie, and S. S. Hecht: Polynuclear aromatic hydrocarbons: effect of chemical structure on tumorigenicity; in: Polynuclear Aromatic Hydrocarbons: Physical and Biological Chemistry; edited by M. Cooke et al., Battelle Press, Columbus, OH, 1982, pp. 1–19.]Search in Google Scholar
[320. Hoffmann, D. and E. L. Wynder: Radioactivity in cigarette smoke; New Engl. J. Med. 307 (1982) 312.]Search in Google Scholar
[321. Hoffmann, D. and E. L. Wynder: Tobacco and tobacco smoke. A continuing public health issue; Tobacco J. Int. 1 (1982) 83–85.]Search in Google Scholar
[322. LaVoie, E. J., S. Amin, S. S. Hecht, K. Furuya, and D. Hoffmann: [A Study of Chemical Carcinogenesis. XXXVIII.] Tumor-initiating activity of dihydrodiols of benzo(b)fluoranthene, benzo(j)fluoranthene, and benzo(k)-fluoranthene; Carcinogenesis 3 (1982) 49–52.]Search in Google Scholar
[323. LaVoie, E. J., V. Bedenko, L. Tulley-Freiler, and D. Hoffmann: Tumor-initiating activity and metabolism of poly-methylated phenanthrenes; Cancer Res. 42 (1982) 4045–4049.]Search in Google Scholar
[324. LaVoie, E. J., G. Briggs, V. Bedenko, and D. Hoffmann: Mutagenicity of substituted carbazoles in Salmonella typhimurium; Mutat. Res. 101 (1982) 141–150.]Search in Google Scholar
[325. LaVoie, E. J., S. S. Hecht, V. Bedenko, and D. Hoffmann: Identification of the mutagenic metabolites of fluoranthene, 2-methylfluoranthene, and 3-methylfluoranthene. Carcino-genesis 3 (1982) 841–846.]Search in Google Scholar
[326. LaVoie, E. J, A. Shigematsu, and D. Hoffmann: Aromatic amines and N-heterocyclics in tobacco distillates; presented at the 184th Natl. Mtg. Am. Chem. Soc., 1982, No. 53.]Search in Google Scholar
[327. Lee, S. J., J. D. Adams, and D. Hoffmann: On the occurrence and analysis of nitrocatechol(s) in cigarette smoke; pre-sented at the 36th TCRC, 1982, Raleigh, NC, No. 12.]Search in Google Scholar
[328. Melikian, A. A., E. J. LaVoie, S. S. Hecht, and D. Hoffmann: Influence of a bay region methyl group on formation of 5-methylchrysene dihydrodiol epoxide: DNA adducts in mouse skin; Cancer Res. 42 (1982) 1239–1242.]Search in Google Scholar
[329. Scott, J. C., K. D. Brunnemann, and D. Hoffmann: N-Nitroso-proline, an indicator for N-nitrosation of amines in tobacco products; presented at the 36th TCRC, 1982, Raleigh, NC, No. 40.]Search in Google Scholar
[330. Tso, T. C., J. F. Chaplin, J. D. Adams, and D. Hoffmann: Simple Correlation and Multiple Regression among Leaf and Smoke Characteristics of Burley Tobaccos; Beitr. Tabakforsch. Int. 11 (1982) 141–150.]Search in Google Scholar
[331. Wynder, E. L. and D. Hoffmann: Tobacco; in: Cancer Epidemiology and Prevention; edited by D. Schottenfeld and J. J. F. Fraumeni, Saunders, Philadelphia, PA, 1982, pp. 277–292 (Chapter 15).]Search in Google Scholar
[332. Adams, J. D., K. D. Brunnemann, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXV.] Rapid method for the analysis of tobacco-specific N-nitrosamines by GLC-TEA. J. Chromatogr. 256 (1983) 347–351.]Search in Google Scholar
[333. Adams, E. A., E. J. LaVoie, and D. Hoffmann: Mutagenicity and metabolism of azaphenanthrenes; in: Polynuclear Aromatic Hydrocarbons - Formation, Metabolism and Measurements; edited by M. Cooke and A. J. Dennis, Battelle Press, Columbus, OH, 1983, pp. 73–87.]Search in Google Scholar
[334. Adams, J. D., E. J. LaVoie, A. Shigematsu, P. Owens, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXX.] Quinoline and methylquinolines in cigarette smoke: Com-parative data and the effect of filtration; J. Anal. Toxicol. 7 (1983) 293–296.]Search in Google Scholar
[335. Adams, J. D., S. J. Lee, N. Vinchkoski, A. Castonguay, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXIII.] On the formation of the tobacco-specific carcino-gen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone during smoking; Cancer Lett. 17 (1983) 339–346.]Search in Google Scholar
[336. Brunnemann, K. D. and D. Hoffmann: GC-TEA of NDELA from tobacco products; in: Environmental Carcinogens -Selected Methods of Analysis. Vol. 6: N-Nitroso Com-pounds, IARC Sci. Publ. 45 (1983) 399–402.]Search in Google Scholar
[337. Brunnemann, K. D. and D. Hoffmann: N-Nitrosodiethanol-amine in tobacco and mainstream and sidestream smoke; in: Environmental Carcinogens - Selected Methods of Analysis. Vol. 6: N-Nitroso Compounds, IARC Sci. Publ. 45 (1983) 85–92.]Search in Google Scholar
[338. Brunnemann, K. D., J. Masaryk, and D. Hoffmann: The role of tobacco stems in the formation of N-nitrosamines in tobacco and cigarette mainstream and sidestream smoke; presented at the 37th TCRC, Washington, DC, 1983, No. 6.10.1021/jf00120a020]Search in Google Scholar
[339. Brunnemann, K. D., J. Masaryk, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXI.] Role of tobacco stems in the formation of N-nitrosamines in tobacco and cigarette mainstream and sidestream smoke; J. Agric. Food Chem. 31 (1983) 1221–1224.]Search in Google Scholar
[340. Brunnemann, K. D., J. C. Scott, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXIX.] N-Nitrosoproline, an indicator for N-nitrosation of amines in processed tobacco; J. Agric. Food Chem. 31 (1983) 905–909.]Search in Google Scholar
[341. Carmella, S. C., S. S. Hecht, D. Hoffmann, J. J. Lam, and T. C. Tso: Effects of carboxymethylation of tobacco fiber on smoke catechol levels; presented at the 37th TCRC, Washington, DC, 1983, No. 40.]Search in Google Scholar
[342. Eisenbrand, G., M. Archer, K. D. Brunnemann, D. Fine, S. S. Hecht, D. Hoffmann, J. Krull, and K. S. Webb: Problems of contamination and artifact formation in nitrosamine sam-pling and analysis; in: Environmental Carcinogens - Se-lected Methods of Analysis, Vol. 6: N-Nitroso Compounds, IARC Sci. Publ. 45 (1983) 25–34.]Search in Google Scholar
[343. Gutenmann, W. H., D. J. Lisk, D. Hoffmann, and J. D. Adams: Selenium in particulates and gaseous fractions of smoke from cigarettes prepared from tobacco grown on fly-ash-amended soil; J. Toxicol. Environ. Health 12 (1983) 385–393.]Search in Google Scholar
[344. Hecht, S. S., J. D. Adams, and D. Hoffmann: HPLC-TEA of Tobacco-Specific Nitrosamines, in: Environmental Carcino-gens - Selected Methods of Analysis. Vol. 6: N-Nitroso Compounds, IARC Sci. Publ. No., 45 (1983) 429–436.]Search in Google Scholar
[345. Hecht, S. S., J. D. Adams, and D. Hoffmann: Tobacco-specific Nitrosamines in Tobacco and Tobacco Smoke; in: Environmental Carcinogens - Selected Methods of Analysis. Vol. 6. N-Nitroso Compounds, IARC Sci. Publ. 45 (1983) 93-101.]Search in Google Scholar
[346. Hecht, S. S., J. D. Adams, S. Numoto, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XXV. Induction of respiratory tract tumors in Syrian golden hamsters by a single dose of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and the effect of smoke inhalation; Carcinogenesis 4 (1983) 1287-1290.]Search in Google Scholar
[347. Hecht, S. S., A. Castonguay, and D. Hoffmann: Nasal cavity carcinogens: possible routes of metabolic activation; in: Nasal Tumors in Animals and Man, Vol. 3: Experimental Nasal Carcinogenesis; edited by G. Reznik and S. F. Stinson, CRC Press Inc., Boca Raton, FL, 1983, pp. 201-232.]Search in Google Scholar
[348. Hecht, S. S., A. Castonguay, A. Rivenson, B. Mu, and D. Hoffmann: Tobacco-specific nitrosamines: carcinogenicity, metabolism, and possible role in human cancer; J. Environ. Sci. Health C1 1 (1983) 1-54.]Search in Google Scholar
[349. Hoffmann, D., J. D. Adams, and N. J. Haley: [Chemical Studies on Tobacco Smoke. LXXVI.] Reported cigarette smoke values: a closer look; Amer. J. Public Health 73 (1983) 1050-1053.]Search in Google Scholar
[350. Hoffmann, D. and K. D. Brunnemann: GC-TEA of Volatile Nitrosamines from Tobacco Products; in: Environmental Carcinogens - Selected Methods of Analysis. Vol. 6: N-Nitroso Compounds, IARC Sci. Publ. 45 (1983) 363-366.]Search in Google Scholar
[351. Hoffmann, D. and K. D. Brunnemann: [A Study of Tobacco Carcinogenesis.] XXVI. Endogenous formation of N-nitrosoproline in cigarette smokers; Cancer Res. 43 (1983) 5570-5574.]Search in Google Scholar
[352. Hoffmann, D., K. D. Brunnemann, and K. S. Webb: Volatile nitrosamines in tobacco and mainstream and sidestream smoke and indoor environments; in: Environmental Carcinogens - Selected Methods of Analysis. Vol. 6: N-Nitroso Compounds, IARC Sci. Publ. 45 (1983) 69-83.]Search in Google Scholar
[353. Hoffmann, D., N. J. Haley, K. D. Brunnemann, J. D. Adams, and E. L. Wynder: Cigarette sidestream smoke: Formation, analysis, and model studies on the uptake by nonsmokers; US-Japan Meeting., New Etiology of Lung Cancer, Honolulu, Hawaii, 1983.]Search in Google Scholar
[354. Hoffmann, D., N. J. Haley, K. D. Brunnemann, and E. L. Wynder: On the endogenous formation of N-nitrosamines in cigarette smokers; presented at the 74th Ann. Meeting Am. Assoc. Cancer Res., 1983, No. 241.]Search in Google Scholar
[355. Hoffmann, D., N. J. Haley, K. D. Brunnemann, and E. L. Wynder: On the endogenous formation of N-nitrosamines in cigarette smokers; Proc. Am. Assoc. Cancer Res. 24 (1983) 61-63.]Search in Google Scholar
[356. Hoffmann, D. and S. S. Hecht: Tobacco and Tobacco Smoke (Volatile and Tobacco-Specific Nitrosamines). II. 2. a: General Aspects; in: Environmental Carcinogens - Selected Methods of Analysis. Vol. 6: N-Nitroso Compounds, IARC Sci. Publ. 45 (1983) 63-67.]Search in Google Scholar
[357. Hoffmann, D., S. S. Hecht, N. J. Haley, K. D. Brunnemann, J. D. Adams, and E. L. Wynder: Tobacco Carcinogenesis: Metabolic Studies in Humans; in: Human Carcinogenesis; edited by CC. Harris and H. N. Autrup, Academic Press, New York, NY, 1983, pp. 809-832.]Search in Google Scholar
[358. Hoffmann, D., S. S. Hecht, and E. L. Wynder: Tumor promot-ers and cocarcinogens in tobacco carcinogenesis; Environ. Health Perspect. 50 (1983) 247-257.]Search in Google Scholar
[359. Hoffmann, D., A. Rivenson, J. D. Adams, A. Juchatz, N. Vinchkoski, and S. S. Hecht: [A Study of Tobacco Carcinogenesis. XXIV.] Effects of route of administration and dose on the carcinogenicity of N-nitrosodiethanolamine in the Syrian golden hamster; Cancer Res. 43 (1983) 2521-2524.]Search in Google Scholar
[360. Hoffmann, D., E. L. Wynder, A. Rivenson, EJ. LaVoie, and S. S. Hecht: Skin Bioassays in Tobacco Carcinogenesis; in: Progress in Experimental Tumor Research. Vol. 26: Skin Painting Techniques and in vivo Carcinogenesis Bioassays; edited by F. Homburger, Karger, Basel, Switzerland, 1983, pp. 43-67.]Search in Google Scholar
[361. LaVoie, EJ., E. A. Adams, and D. Hoffmann: Identification of the metabolites of benzo(f)quinoline and benzo(h)-quinoline formed by rat liver homogenate; Carcinogenesis 4 (1983) 1133-1138.]Search in Google Scholar
[362. LaVoie, EJ., E. A. Adams, A. Shigematsu, and D. Hoffmann: On the metabolism of quinoline and isoquinoline: possible molecular basis for differences in biological activities; Carcinogenesis 4 (1983) 1169-1173.]Search in Google Scholar
[363. LaVoie, EJ., D. T. Coleman, R. L. Tonne, and D. Hoffmann: Mutagenicity, Tumor Initiating Activity and Metabolism of Methylated Anthracenes, in: Polynuclear Aromatic Hydro-carbons - Formation, Metabolism and Measurements; edited by M. Cooke and A J. Dennis, Battelle Press, Columbus, OH, 1983, pp. 785-798.]Search in Google Scholar
[364. LaVoie, EJ., S. S. Hecht, and D. Hoffmann: Molecular basis for the structure-carcinogenicity relationships of polynuclear aromatic hydrocarbons; in: Structure-Activity Correlation as a Predictive Tool in Toxicology. Fundamentals, Methods, and Application; edited by L. Goldberg, Hemisphere Publ. Co., New York, NY, 1983, pp. 263-274.]Search in Google Scholar
[365. LaVoie, EJ., L. Tulley-Freiler, V. Bedenko, and D. Hoffmann: Mutagenicity of substituted phenanthrenes in Salmonella typhimurium; Mutat. Res. 116 (1983) 91-102.]Search in Google Scholar
[366. Masaryk, J., K. D. Brunnemann, D. Hoffmann: Model studies on nicotine analogues, synthesis and nitrosation reactions; presented at the 37th TCRC, Washington, DC, 1983, No. 8.]Search in Google Scholar
[367. Melikian, AA., EJ. LaVoie, S. S. Hecht, and D. Hoffmann: 5-Methylchrysene metabolism in mouse epidermis in vivo, diol epoxide-DNA adduct persistence, and diol epoxide reactivity with DNA as potential factors influencing the predominance of 5-methylchrysene-1,2-diol-3,4-epoxide-DNA adducts in mouse epidermis; Carcinogenesis 4 (1983) 843-849.]Search in Google Scholar
[368. Melikian, A. A., EJ. LaVoie, S. S. Hecht, and D. Hoffmann: On the enhancing effect of a bay-region methyl group in 5-methylchrysene carcinogenesis; in: Polynuclear Aromatic Hydrocarbons Formation, Metabolism and Measurements; edited by M. Cooke and AJ. Dennis, Battelle Press, Columbus, OH, 1983, pp. 861-875.]Search in Google Scholar
[369. Rice, J. E., V. Bedenko, EJ. LaVoie, and D. Hoffmann: Studies on the metabolism of fluoranthene, 2-methy lfluoran-thene, and 3-methylfluoranthene; in: Polynuclear Aromatic Hydrocarbons - Formation, Metabolism and Measurements; edited by M. Cooke and AJ. Dennis, Battelle Press, Columbus, OH, 1983, pp. 1009-1020.]Search in Google Scholar
[370. Rice, J. E., EJ. LaVoie, and D. Hoffmann: Synthesis of the isomeric phenols and trans-2,3-dihydrodiol of fluoranthene; J. Org. Chem. 48 (1983) 2360-2363.]Search in Google Scholar
[371. Rivenson, A., K. Furuya, S. S. Hecht, and D. Hoffmann: Experimental nasal cavity tumors induced by tobacco-specific nitrosamines (TSNA); in: Nasal Tumor in Animals and Man, Vol. 3: edited by G. Reznik and S. F. Stinson, CRC Press Inc., Boca Raton, FL, 1983, pp. 79-113.]Search in Google Scholar
[372. Shigematsu, A., J. D. Adams, J. Camanzo, EJ. LaVoie, and D. Hoffmann: Steam-volatile components in the tobacco and mainstream smoke of cigarettes with low ‘tar’ yields; presented at the 37th TCRC, Washington, DC, 1983, No. 12.]Search in Google Scholar
[373. Tso, T. C., J. D. Adams, NJ. Haley, and D. Hoffmann: The smokers’ dependence on nicotine and the fate of nicotine during tobacco curing and smoking, and its reduction; in: Proc. 5th World Conf. on Smoking and Health, Winnipeg, Canada, 1983, pp. 229-238.]Search in Google Scholar
[374. Wenke, G. and D. Hoffmann: A study of betel quid carcinogenesis. 1. On the in vitro N-nitrosation of arecoline; Carcinogenesis 4 (1983) 169-172.]Search in Google Scholar
[375. Adams, J. D., EJ. LaVoie, M. O'Donnell, and D. Hoffmann: On the pharmacokinetics of tobacco-specific N-nitros-amines; in: N-Nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer, IARC Sci. Publ. 57 (1984) 779–785.]Search in Google Scholar
[376. Adams, J. D., S. J. Lee, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXVIII.] Carcinogenic agents in cigarette smoke and the influence of nitrate on their formation; Carcinogenesis 5 (1984) 221–223.]Search in Google Scholar
[377. Adams, J. D., P. Owens-Tucciarone, and D. Hoffmann: Tobacco carcinogenesis and asbestos fibers: a model study; presented at the 75th Ann. Meeting Am. Assoc. Cancer Res., Toronto, Canada, 1984.]Search in Google Scholar
[378. Brunnemann, K. D., S. J. Lee, S. Adams, and D. Hoffmann: Occurrence of N-nitrosamines in chewing tobacco: a closer look; presented at the 38th TCRC, Atlanta, GA, 1984, No. 26.]Search in Google Scholar
[379. Brunnemann, K. D., J. C. Scott, N. J. Haley, and D. Hoffmann: Endogenous formation of N-nitrosoproline upon cigarette smoke inhalation; in: N-Nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer, IARC Sci. Publ. 57 (1984) 819–828.]Search in Google Scholar
[380. Brunnemann, K. D., J. C. Scott, and D. Hoffmann: Develop-ment of an HPLC postcolumn photolysis detector for the determination of N-nitrosamides; presented at the CO-RESTA Congress Vienna, Austria, 1984, No. S11.]Search in Google Scholar
[381. Carmella, S. G., S. S. Hecht, T. C. Tso, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXVII.] Roles of tobacco cellulose, sugars, and chlorogenic acid as precursors to catechol in cigarette smoke; J. Agric. Food Chem. 32 (1984) 267–273.]Search in Google Scholar
[382. El-Bayoumi, K., M. O'Donnell, S. S. Hecht, and D. Hoffmann: The influence of tobacco nitrate on aromatic amines and nitro-aromatics in cigarette smoke; presented at the 38th TCRC, 1984, Atlanta, GA, No. 36.]Search in Google Scholar
[383. Hecht, S. S., A. Castonguay, F. -L. Chung, and D. Hoffmann: Carcinogenicity and metabolism activation of tobacco-specific nitrosamines: current status and future prospects; in: N-Nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer, IARC Sci. Publ. 57 (1984) 763–778.]Search in Google Scholar
[384. Hoffmann, D., K. D. Brunnemann, and J. D. Adams: Tobacco-specific N-nitrosamines (TSNA): recent progress on occurrence, formation and reduction; presented at the CORESTA Congress Vienna, Austria, 1984, No. S15.]Search in Google Scholar
[385. Hoffmann, D., K. D. Brunnemann, J. D. Adams, and N. J. Haley: Indoor air pollution by tobacco smoke: model studies on the uptake by nonsmokers; in: Indoor Air. Radon, Passive Smoking, Particulates and Housing Epidemiology. Proc. 3rd Internatl. Conf. on Indoor Air Quality and Climate Stock-holm, Sweden, Vol. 2, D 17, 1984, pp. 313–318.]Search in Google Scholar
[386. Hoffmann, D., K. D. Brunnemann, J. D. Adams, and S. S. Hecht: Formation and analysis of N-nitrosamines in tobacco products and their endogenous formation in tobacco con-sumers; in: N-Nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer, IARC Sci. Publ. 57 (1984) 743–762.]Search in Google Scholar
[387. Hoffmann, D., N. J. Haley, J. D. Adams, and K. D. Brunne-mann: Tobacco Sidestream Smoke: Uptake by Nonsmokers; Prev. Med. 13 (1984) 608–617.]Search in Google Scholar
[388. Hoffmann, D., A. Rivenson, S. Amin, and S. S. Hecht: [A Study of Tobacco Carcinogenesis. XXVII.] Dose-Response Study on the Carcinogenicity of Tobacco-Specific N-Nitrosamines in F344 rats; J. Cancer Res. Clin. Oncol. 108 (1984) 81–86.]Search in Google Scholar
[389. LaVoie, E. J., A. Shigematsu, E. A. Adams, J. Rigotty, and D. Hoffmann: Tumor-initiating activity of quinoline and methylated quinolines on the skin of SENCAR mice; Cancer Lett. 22 (1984) 269–273.]Search in Google Scholar
[390. Melikian, A. A., S. Amin, S. S. Hecht, D. Hoffmann, J. Pataki, and R. G. Harvey: Identification of the major adducts formed by reaction of 5-methylchrysene anti-dihydrodiol epoxides with DNA in vitro; Cancer Res. 44 (1984) 2524-2529.]Search in Google Scholar
[391. Sasson, I. M., D. T. Coleman, EJ. LaVoie, D. Hoffmann, and E. L. Wynder: Influence of diet and smoking on the mutage-nic activity of human urine: vegan diet increases mutageni-city; presented at the 75th Ann. Meeting Am. Assoc. Cancer Res., Toronto, Canada, 1984, No. 102.]Search in Google Scholar
[392. Wenke, G., K. D. Brunnemann, D. Hoffmann, and S. V. Bhide: A Study of Betel Quid Carcinogenesis. 4. Analysis of the saliva of betel chewers. A preliminary report; J. Cancer Res. Clin. Oncol. 108 (1984) 110-113.]Search in Google Scholar
[393. Wenke, G., A. Rivenson, K. D. Brunnemann, and D. Hoffmann: A Study of Betel Quid Carcinogenesis. 2. On the formation of N-nitrosamines during betel quid chewing; in: N-Nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer, IARC Sci. Publ. 57 (1984) 859-866.]Search in Google Scholar
[394. Wenke, G., A. Rivenson, and D. Hoffmann: A Study of Betel Quid Carcinogenesis. 3. 3-(Methylnitrosamino)-propionitrile, a powerful carcinogen in F344 rats; Carcinogenesis 5 (1984) 1137-1140.]Search in Google Scholar
[395. Wynder, E. L., M. T. Goodman, and D. Hoffmann: Demo-graphic aspects of the low-yield cigarette; J. Natl. Cancer Inst. 72 (1984) 817-822.]Search in Google Scholar
[396. Adams, J. D., EJ. LaVoie, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XXVIII.] On the pharmacokinetics of tobacco-specific N-nitrosamines in Fischer rats; Carcinogenesis 6 (1985) 509-511.]Search in Google Scholar
[397. Adams, J. D., EJ. LaVoie, KJ. O'Mara-Adams, D. Hoffmann, K. D. Carey, and M. V. Marshall: [A Study of Tobacco Carcinogenesis. XXIX.] Pharmacokinetics of N’-nitrosonor-nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-buta-none in laboratory animals; Cancer Lett. 28 (1985) 195-201.]Search in Google Scholar
[398. Adams, J. D., KJ. O'Mara-Adams, and D. Hoffmann: On the mainstream-sidestream distribution of smoke components from commercial cigarettes; presented at the 39th TCRC, Montreal, Canada, 1985, No. 34.]Search in Google Scholar
[399. Bache, CA., DJ. Lisk, GJ. Doss, D. Hoffmann, and J. D. Adams: Cadmium and nickel in mainstream particulates of cigarettes containing tobacco grown on a low cadmium soil-sludge mixture; J. Environ. Toxicol. 16 (1985) 547-552.]Search in Google Scholar
[400. Brunnemann, K. D., L. Genoble, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXIV.] N-Nitrosamines in chewing tobacco: an international comparison; J. Agr. Food Chem. 33 (1985) 1178-1181.]Search in Google Scholar
[401. Chou, D., K. D. Brunneman, J. D. Adams, and D. Hoffmann: On the isolation and identification of new tobacco-specific N-nitrosamines; presented at the 39th TCRC, Montreal, Canada, 1985, No. 22.]Search in Google Scholar
[402. El-Bayoumy, K., M. O'Donnell, S. S. Hecht, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXII.] On the analysis of 1-nitronaphthalene, 1-nitropyrene, and 6-nitrochrysene in cigarette smoke; Carcinogenesis 6 (1985) 505-507.]Search in Google Scholar
[403. Haley, NJ. and D. Hoffmann: Analysis for nicotine and cotinine in hair to determine cigarette smoker status; Clin. Chem. 31 (1985) 1598-1600.]Search in Google Scholar
[404. Haley, NJ., D. W. Sepkovic, D. Hoffmann, and E. L. Wynder: Cigarette smoking as a risk for cardiovascular disease. Part VI. Compensation with nicotine availability as a single variable; Clin. Pharmacol. Ther. 38 (1985) 164-170.]Search in Google Scholar
[405. Hecht, S. S., A. Amin, AA. Melikian, EJ. LaVoie, and D. Hoffmann: Effects of methy l and fluorine substitution on the metabolic activation and tumorigenicity of polycyclic aromatic hydrocarbons; Amer. Chem. Soc. Symp. Series 238 (1985) 85-105.]Search in Google Scholar
[406. Hecht, S. S., L. Radok, S. Amin, K. Huie, AA. Melikian, D. Hoffmann, J. Pataki, and R. G. Harvey: Tumorigenicity of 5-methylchrysene dihydrodiols and dihydrodiol epoxides in newborn mice and on mouse skin; Cancer Res. 45 (1985) 1449–1452.]Search in Google Scholar
[407. Hoffmann, D. and S. S. Hecht: [A Study of Tobacco Carcinogenesis. XXX.] Perspectives in Cancer Research. Nicotine-derived N-nitrosamines and tobacco-related cancer: current status and future directions; Cancer Res. 45 (1985) 935–944.]Search in Google Scholar
[408. Hoffmann, D., S. S. Hecht, N. J. Haley, K. D. Brunnemann, J. D. Adams, and E. L. Wynder: Tumorigenic agents in tobacco products and their uptake by chewers, smokers and nonsmokers; J. Cell. Biochem. Suppl. 9C (1985) 33.]Search in Google Scholar
[409. Hoffmann, D., E. J. LaVoie, and S. S. Hecht: Nicotine: a precursor for carcinogens. Cancer Lett. 26 (1985) 67–75.]Search in Google Scholar
[410. Hoffmann, D., A. Melikian, J. D. Adams, K. D. Brunnemann, and N. J. Haley: New Aspects of Tobacco Carcinogenesis; in: Carcinogenesis; edited by M. J. Maas et al., Raven Press, New York, NY, 1985, pp. 239–256.]Search in Google Scholar
[411. Hoffmann, D., A. S. Rivenson, and S. S. Hecht: The Role of Nicotine in Tobacco Carcinogenesis; in: Hommage au Professeur Rene Truhaut; edited by Comité d'organisation du jubilé scientifique du Prof. R. Truhaut, Tardy Quercy (S. A.), Cahors, France, 1985, pp. 491–495.]Search in Google Scholar
[412. Hoffmann, D. and E. L. Wynder: The selective reduction of cigarette smoke constituents. Proc. 1st Member Congress China Tobacco Soc., Beijing, China, 1985, pp. 234–279.]Search in Google Scholar
[413. LaVoie, E. J., E. A. Adams, A. Shigematsu, and D. Hoffmann: Metabolites of phenanthridine formed by rat liver homogenate; Drug Metab. Dispos. 13 (1985) 71–75.]Search in Google Scholar
[414. LaVoie, E. J., D. T. Coleman, J. E. Rice, N. G. Geddie, and D. Hoffmann: Tumor-initiating activity, mutagenicity, and metabolism of methylated anthracenes; Carcinogenesis 6 (1985) 1483–1488.]Search in Google Scholar
[415. LaVoie, E. J., A. Shigematsu, B. Mu, A. Rivenson, and D. Hoffmann: The effects of catechol on the urinary bladder of rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine; Gann: Jpn. J. Cancer Res. 76 (1985) 266–271.]Search in Google Scholar
[416. LaVoie, E. J., A. Shigematsu, A. Rivenson, B. Mu, and D. Hoffmann: Evaluation of the effects of cotinine and nicotine-N’-oxides on the development of tumors in rats initiated with N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide; J. Natl. Cancer Inst. 75 (1985) 1075–1081.]Search in Google Scholar
[417. LaVoie, E. J., A. Shigematsu, P. L. Tucciarone, J. D. Adams, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXIII.] Comparison of the steam-volatile components of commercial cigarette, pipe, and chewing tobaccos; J. Agric. Food Chem. 33 (1985) 876–879.]Search in Google Scholar
[418. Melikian, A. A., S. S. Hecht, D. Hoffmann, J. Pataki, and R. G. Harvey: Analysis of syn- and anti-1,2-dihydroxy-3,4-epoxy-1,2,3,4-tetrahydro-5-methylchrysene-deoxyribo-nucleoside adducts by boronate chromatography; Cancer Lett. 27 (1985) 91–97.]Search in Google Scholar
[419. Melikian, A. A., J. M. Leszczynska, S. Amin, S. S. Hecht, D. Hoffmann, J. Pataki, and R. G. Harvey: Rates of hydrolysis and extents of DNA-binding of 5-methylchrysene dihydro-diol epoxides; Cancer Res. 45 (1985) 1990–1996.]Search in Google Scholar
[420. Sasson, I. M., D. T. Coleman, E. J. LaVoie, D. Hoffmann, and E. L. Wynder: Mutagens in human urine: Effects of cigarette smoking and diet; Mutat. Res. 158 (1985) 149–157.]Search in Google Scholar
[421. Sasson, I. M., N. J. Haley, D. Hoffmann, E. L. Wynder, D. Hellberg, and S. Nilsson: Cigarette Smoking and Neoplasia of the Uterine Cervix: Smoke Constituents in Cervical Mucus; N. Engl. J. Med. 312 (1985) 315–316.]Search in Google Scholar
[422. Wynder, E. L., M. T. Goodman, and D. Hoffmann: Lung Cancer Etiology: Challenges of the Future; in: Cancer of the Respiratory Tract: Predisposing Factors; edited by M. J. Maas et al., Raven Press, New York, NY, 1985, pp. 39–62.]Search in Google Scholar
[423. Zaridze, D. G., M. Blettner, N. N. Trapeznikov, J. P. Kuvshinov, E. G. Matiakin, B. P. Poljakov, B. K. Poddubni, S. M. Parshikova, V. I. Rottenberg, F. S. Chamrakulov, M. C. Chodjaeva, H. F. Stich, M. P. Rosin, D. I. Thurnham, D. Hoffmann, and K. D. Brunnemann: Survey of a population with a high incidence of oral and esophageal cancer; Int. J. Cancer 36 (1985) 153–158.]Search in Google Scholar
[424. Adams, J. D., P. L. Tucciarone, L. Genoble, K. D. Brunne-mann, and D. Hoffmann: On the anaylsis of N-nitroso compounds in tobacco and tobacco smoke by capillary GC-TEA; presented at the 40th TCRC, Knoxville, TN, No. 48.]Search in Google Scholar
[425. Bache, C. A., C. M. Reid, D. Hoffmann, J. D. Adams, and D. J. Lisk: Cadmium in smoke particulates of regular and filter cigarettes containing low and high cadmium concentrations; Bull. Environ. Contam. Toxicol. 36 (1986) 372–375.]Search in Google Scholar
[426. Brunnemann, K. D., B. Prokopczyk, D. Hoffmann, J. Nair, H. Ohshima, and H. Bartsch: Laboratory studies on oral cancer and smokeless tobacco; in: Mechanisms in Tobacco Carcinogenesis, Banbury Report, No. 23; edited by D. Hoffmann and C. C. Harris, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986, pp. 197–213.]Search in Google Scholar
[427. Brunnemann, K. D., R. Onrust, and D. Hoffmann: Determi-nation of volatile carbonyl compounds in tobacco headspace and tobacco smoke; presented at the 40th TCRC, Knoxville, 1986, No. 47.]Search in Google Scholar
[428. Connolly, G. N., D. M. Winn, S. S. Hecht, J. E. Henningfield, B. Walker Jr, and D. Hoffmann: The reemergence of smokeless tobacco; N. Engl. J. Med. 314 (1986) 1020–1027.10.1056/NEJM198604173141605]Search in Google Scholar
[429. Donahue, J. M., K. El-Bayoumi, S. S. Hecht, and D. Hoffmann: Aromatic amines in human urine; presented at the 77th Ann. Meeting Am. Assoc. Cancer Res., 1986, No. 373.]Search in Google Scholar
[430. El-Bayoumy, K., J. M. Donahue, S. S. Hecht, and D. Hoffmann: Analysis of aniline and o-toluidine in human urine; in: Mechanisms in Tobacco Carcinogenesis, Banbury Report, No. 23; edited by D. Hoffmann and C. C. Harris, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986, pp. 77–84.]Search in Google Scholar
[431. El-Bayoumy, K., J. M. Donahue, S. S. Hecht, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XXXIII.] Identification and quantitative analysis of aniline and toluidines in human urine; Cancer Res. 46 (1986) 6064–6067.]Search in Google Scholar
[432. Haley, N. J., D. Hoffmann, and E. L. Wynder: Uptake of Tobacco Smoke Components; in: Mechanisms in Tobacco Carcinogenesis, Banbury Report, No. 23; edited by D. Hoffmann and C. C. Harris, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986, pp. 3–19.]Search in Google Scholar
[433. Hecht, S. S., P. G. Foiles, S. G. Carmella, N. Trushin, A. Rivenson, and D. Hoffmann: Recent studies on the meta-bolic activation of tobacco-specific nitrosamines: Prospects for dosimetry in humans; in: Mechanisms in Tobacco Carcinogenesis, Banbury Report, No. 23; edited by D. Hoffmann and C. C. Harris, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986, pp. 245–257.]Search in Google Scholar
[434. Hecht, S. S., A. Rivenson, J. Braley, J. DiBello, J. D. Adams, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XXXII.] Induction of oral cavity tumors in F344 rats by tobacco-specific nitrosamines and snuff; Cancer Res. 46 (1986) 4162–4166.]Search in Google Scholar
[435. Hoffmann, D., K. D. Brunnemann, J. D. Adams, and S. S. Hecht: Laboratory studies on snuff-dipping and oral cancer; Cancer J. 1 (1986) 10–13.]Search in Google Scholar
[436. Hoffmann, D., N. H. Harley, I. Fisenne, J. D. Adams, and K. D. Brunnemann: [A Study of Tobacco Carcinogenesis. XXXI.] Carcinogenic agents in snuff; J. Natl. Cancer Inst. 76 (1986) 435–437.]Search in Google Scholar
[437. Hoffmann, D. and C. C. Harris: Mechanisms in tobacco carcinogenesis; Banbury Report, No. 23; edited by D. Hoffmann and C. C. Harris, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986, pp. 428.]Search in Google Scholar
[438. Hoffmann, D., S. S. Hecht, A. A. Melikian, N. J. Haley, K. D. Brunnemann, J. D. Adams, and E. L. Wynder: Tumorigenic agents in tobacco products and their uptake by chewers, smokers and nonsmokers; in: Biochemical and Molecular Epidemiology of Cancer; edited by C. C. Harris, Alan Liss Inc., New York, NY, 1986, pp. 191–204.]Search in Google Scholar
[439. Hoffmann, D. and E. L. Wynder: The tumor initiator in tobacco smoke; Proc. Am. Assoc. Cancer Res., Chicago, 7 (1986) 32.]Search in Google Scholar
[440. Hoffmann, D. and E. L. Wynder: [A Study of Tobacco Car-cinogenesis. XXXVII.] Chemical constituents and bioacti-vity of tobacco smoke; in: Tobacco – A Major International Health Hazard, IARC Sci. Publ. 74 (1986) 145–165.]Search in Google Scholar
[441. Kuller, L. H., L. Garfinkel, P. Correa, N. Haley, D. Hoffmann, S. Preston-Martin, and D. Sandler: Contribution of passive smoking to respiratory cancer; Environ. Health Perspect. 70 (1986) 57–69.]Search in Google Scholar
[442. LaVoie, E. J., J. D. Adams, J. Reinhardt, A. Rivenson, and D. Hoffmann: Toxicity studies on clove cigarette smoke and constituents of clove: determination of the LD50 of eugenol by intratracheal instillation in rats and hamsters; Arch. Toxicol. 59 (1986) 78–81.]Search in Google Scholar
[443. LaVoie, E. J., J. D. Adams, J. Reinhardt, A. Rivenson, and D. Hoffmann: Comments on the toxicology of constituents in clove cigarette smoke; Arch. Toxicol. 59 (1986) 298–299.]Search in Google Scholar
[444. LaVoie, E. J., I. M. Sasson, D. Hoffmann, M. V. Marshall, and W. Rodgers: Mutagens in the urine of cigarette smokers; in: Mechanisms of Tobacco Carcinogenesis, Banbury Report 23; edited by D. Hoffmann and C. C. Harris, 1986, pp. 121–136.]Search in Google Scholar
[445. Melikian, A. A., J. M. Leszczynska, S. S. Hecht, and D. Hoffmann: Effects of the co-carcinogen catechol on benzo[a]pyrene metabolism and DNA adduct formation in mouse skin; Carcinogenesis 7 (1986) 9–15.]Search in Google Scholar
[446. Palladino, G., J. D. Adams, K. D. Brunnemann, N. J. Haley, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XXXVI.] Snuff-dipping in college students: a clinical profile; Mil. Med. 151 (1986) 342–346.]Search in Google Scholar
[447. Parsa, I., C. A. Foye, C. M. Cleary, and D. Hoffmann: Differences in metabolism and biological effects of NNK in human target cells; in: Mechanisms of Tobacco Carcino-genesis, Banbury Report, No. 23; edited by D. Hoffmann and C. C. Harris, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1986, pp. 233–244.]Search in Google Scholar
[448. Rivenson, A., D. Hoffmann, and S. S. Hecht: Local and regional tumors induced by smokeless tobacco and its components in Fischer rats; 14th Int. Cancer Cong., Buda-pest, Hungary (1986).]Search in Google Scholar
[449. Sepkovic, D. W., N. J. Haley, and D. Hoffmann: Elimination from the body of tobacco products by smokers and passive smokers; J. Am. Med. Assoc. 256 (1986) 863.]Search in Google Scholar
[450. Zaridze, D. G., M. Blettner, E. G. Matiakin, B. P. Poljakov, H. F. Stich, M. P. Rosin, D. Hoffmann, and K. D. Brunne-mann: The effect of nass use and smoking on the risk of oral leukoplakia; Cancer Detect. Prevent. 9 (1986) 435–440.]Search in Google Scholar
[451. Abbaspour, A., S. S. Hecht, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXVII.] Synthesis of 5’-carboxy-N’-nitrosonornicotine and 5’-[14C]carboxy-N’-nitrosonornicotine; J. Org. Chem. 52 (1987) 3474–3477.]Search in Google Scholar
[452. Adams, J. D., K. J. O'Mara-Adams, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXVI.] Toxic and carcinogenic agents in undiluted mainstream smoke and sidestream smoke of different types of cigarettes; Carcinogenesis 8 (1987) 729–731.]Search in Google Scholar
[453. Adams, J. D., P. Owens-Tucciarone, and D. Hoffmann: Tobacco-specific N-nitrosamines in dry snuff; Food Chem. Toxicol. 25 (1987) 245–246.10.1016/0278-6915(87)90090-1]Search in Google Scholar
[454. Bache, C. A., D. J. Lisk, B. S. Shane, D. Hoffmann, and J. D. Adams: Effectiveness of cigarette filter tips for reducing cadmium in relation to other mainstream smoke constituents; Drug Chem. Toxicol. 10 (1987) 189–193.]Search in Google Scholar
[455. Brunnemann, K. D., L. Genoble, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXV.] Identification and analysis of a new tobacco-specific N-nitrosamine, 4-(methylnitrosamino)-4-(3-pyridyl)-1-butanol; Carcinogene-sis 8 (1987) 465–469.]Search in Google Scholar
[456. Brunnemann, K. D., N. J. Haley, J. D. Adams, D. W. Sepkovic, and D. Hoffmann: Model studies on the uptake of nicotine after exposure to environmental tobacco smoke (ETS); presented at the 41st TCRC, NC, 1987, No. 31.]Search in Google Scholar
[457. Brunnemann, K. D., A. Rivenson, J. D. Adams, S. S. Hecht, and D. Hoffmann: A study of snuff carcinogenesis; in: The Relevance of N-Nitroso Compounds to Human Cancer: Exposures and Mechanisms, IARC Sci. Publ. 84 (1987) 456–459.]Search in Google Scholar
[458. El-Bayoumy, K., M. O'Donnell, and D. Hoffmann: Determi-nation of aromatic amines in sidestream smoke; in: Environ-mental Carcinogens: Methods of Analysis and Exposure Measurement, IARC Sci. Publ. 81 (1987) 269–277.]Search in Google Scholar
[459. Gutenmann, W. H., D. J. Lisk, B. S. Shane, D. Hoffmann, and J. D. Adams: Selenium in mainstream and sidestream smoke of cigarettes containing fly ash-grown tobacco; Drug Chem. Toxicol. 10 (1987) 181–187.]Search in Google Scholar
[460. Haley, N. J., J. D. Adams, J. Alzofon, and D. Hoffmann: Uptake of sidestream smoke by Syrian golden hamsters; Toxicol. Lett. 35 (1987) 83–88.]Search in Google Scholar
[461. Haley, N. J., J. D. Adams, C. M. Axelrad, and D. Hoffmann: Sidestream smoke uptake by Syrian golden hamsters in an inhalation bioassay; in: Proc. 4th International Conf. Indoor Air ‘87, Berlin, Germany, Vol. 2 (Environmental tobacco smoke, multicomponent studies, radon, sick buildings, odors and irritants, hyperreactivities and allergies; edited by B. Seifert et al., Institute for Water, Soil and Air Hygiene) 1987, pp. 68–73.]Search in Google Scholar
[462. Hoffmann, D., J. D. Adams, and K. D. Brunnemann: A critical look at N-nitrosamines in environmental tobacco smoke; Toxicol. Lett. 35 (1987) 1–8.]Search in Google Scholar
[463. Hoffmann, D., J. D. Adams, D. Lisk, I. Fisenne, and K. D. Brunnemann: [A Study of Tobacco Carcinogenesis. XXXIX.] Toxic and carcinogenic agents in dry and moist snuff; J. Natl. Cancer Inst. 79 (1987) 1281–1286.]Search in Google Scholar
[464. Hoffmann, D., K. D. Brunnemann, N. J. Haley, D. W. Sepko-vic, and J. D. Adams: Nicotine uptake by nonsmokers exposed to passive smoking under controlled conditions and the elimination of cotinine; in: Proc. 4th International Conf. Indoor Air ‘87, Berlin, Germany, Vol. 2, (Environmental tobacco smoke, multicomponent studies, radon, sick buildings, odors and irritants, hyperreactivities and allergies; edited by B. Seifert et al., Institute for Water, Soil and Air Hygiene), 1987, pp. 13–17.]Search in Google Scholar
[465. Hoffmann, D. and I. Hoffmann: Significance of Exposure to Sidestream Tobacco Smoke; in: Environmental Carcinogens - Methods of Analysis and Exposure Measurement. Vol. 9: Passive Smoking, IARC Sci. Publ. 81 (1987) 3–10.]Search in Google Scholar
[466. Hoffmann, D., E. J. LaVoie, and S. S. Hecht: Chemical fractionation and bioassay of complex mixtures: studies in tobacco carcinogenesis; in: Health and Environmental Research on Complex Organic Mixtures; edited by R. H. Gray et al., Battelle, Pacific Northwest Laboratory, Rich-land, WA, 1987, pp. 151–165.]Search in Google Scholar
[467. Hoffmann, D., E. L. Wynder, S. S. Hecht, K. D. Brunnemann, E. J. LaVoie, and N. J. Haley: Chemical carcinogens in tobacco; in: Cancer Risks: Strategies for Elimination; edited by P. Bannasch, Springer-Verlag, Berlin, 1987, pp. 101–113.10.1007/978-3-642-71843-4_9]Search in Google Scholar
[468. Prokopczyk, G., J. D. Adams, E. J. LaVoie, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XXXIV.] Effect of snuff and nicotine on DNA methylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone; Carcinoge-nesis 8 (1987) 1395–1397.]Search in Google Scholar
[469. Prokopczyk, B., K. D. Brunnemann, P. Bertinato, and D. Hoffmann:The role of N- (nitrosomethylamino)propionitrile in betel-quid carcinogenesis; IARC Monogr. 84 (1987) 470–473.]Search in Google Scholar
[470. Prokopczyk, B., A. Rivenson, P. Bertinato, K. D. Brunnemann, and D. Hoffmann: [A study of betel quid carcinogenesis. V.] 3-(Methylnitrosamino)propionitrile: occurrence in saliva of betel quid chewers, carcinogenicity and DNA methylation in F344 rats; Cancer Res. 47 (1987) 467-471.]Search in Google Scholar
[471. Schiffmann, M. H., NJ. Haley, J. S. Felton, A. W. Andrews, R. A. Kaslow, W. D. Lancaster, RJ. Kurman, LA. Brinton, L. B. Lannom, and D. Hoffmann: Biochemical epidemiology of cervical neoplasia: measuring cigarette smoke constitu-ents in the cervix; Cancer Res. 47 (1987) 3886-3888.]Search in Google Scholar
[472. Tucciarone, P. L., J. D. Adams, E. L. LaVoie, M. Kagan, and D. Hoffmann: Quantitative analyses of steam distillates and aqueous extracts of commercial smokeless tobaccos; presented at the 41st TCRC, 1987, Greensboro, NC, No. 11.]Search in Google Scholar
[473. Brunnemann, K. D., M. R. Kagan, and D. Hoffmann: Analy-sis of selected gas phase components by GC-MSD; pre-sented at the 42nd TCRC, Lexington, KY, 1988, No. 18.]Search in Google Scholar
[474. Brunnemann, K. D., A. Rivenson, A. Czech, EJ. LaVoie, and D. Hoffmann: Isolation, identification, and bioassay of the tobacco-specific N-nitrosamine 4-methylnitrosamino-(3-pyridyl)-1-butanol; Proc. Am. Assoc. Cancer Res. 29 (1988) No. 332.]Search in Google Scholar
[475. Djordjevic, M. V., K. D. Brunnemann, and D. Hoffmann: Identification and analy sis of nicotine-derived N-nitrosamino acid and other nitrosamino acids in tobacco; presented at the 42nd TCRC, Lexington, KY, 1988, No. 41.]Search in Google Scholar
[476. Haley, N. J., D. W. Sepkovic, E. Louis, and D. Hoffmann: Absorption and elimination by smokers, nonsmokers, and chewers of nicotine gum; in: The Pharmacology of Nicotine; edited by M. J. Rand and K. Thurau, IRL Press, Washington, DC, 1988, pp. 20-21.]Search in Google Scholar
[477. Hecht, S. S., A. Abbaspour, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XLII. Bioassay in A/J mice of some structural analogues of tobacco-specific nitrosamines; Cancer Lett. 42 (1988) 141-145.]Search in Google Scholar
[478. Hecht, S. S., S. G. Carmella, N. Trushin, T. E. Spratt, P. G. Foiles, and D. Hoffmann: Approaches to the development of assays for interaction of tobacco specific nitrosamines with hemoglobin and DNA; in: Methods for Detecting DNA Damaging Agents in Humans: Applications in Cancer Epidemiology and Prevention, IARC Sci. Publ. 89 (1988) 121-128.]Search in Google Scholar
[479. Hecht, S. S. and D. Hoffmann: Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke; Carcinogenesis 9 (1988) 875-884.]Search in Google Scholar
[480. Hellberg, D., S. Nilsson, N. J. Haley, D. Hoffmann, and E. Wynder: Smoking and cervical intraepithelial neoplasia -nicotine and continine in serum and cervical mucus in smokers and nonsmokers; Am. J. Obstet. Gynecol. 158 (1988) 910-913.]Search in Google Scholar
[481. Hoffmann, D.: Krank durch Passivrauchen? Oral presentation held on the Symposium ‘Krank durch Passivrauchen?’ Vienna, Austria, 1988, in: Transcription of a live recording, pp. 41–45.]Search in Google Scholar
[482. Hoffmann, D., J. D. Adams, EJ. LaVoie, and S. S. Hecht: Biochemistry, pharmacokinetics and carcinogenicity of nicotine-derived nitrosamines; in: Pharmacology of Nicotine; edited by M. J. Rand and K. Thurau, IRL Press, Oxford, UK, 1988, pp. 43-60.]Search in Google Scholar
[483. Hoffmann, D., K. D. Brunnemann, and S. Venitt: Carcino-genic nitrosamines in oral snuff; Lancet 331 (1988) 1232.]Search in Google Scholar
[484. Hoffmann, D. and S. S. Hecht: Smokeless tobacco and cancer; ISI Atlas of Science. Pharmacology 2 (1988) 46-52.]Search in Google Scholar
[485. Prokopczyk, B., P. Bertinato, and D. Hoffmann: Cyano-ethylation of DNA in vivo by 3-(methy lnitrosamino)proprionitrile, an areca-derived carcinogen; Cancer Res. 48 (1988) 6780–6784.]Search in Google Scholar
[486. Prokopczyk, B., P. Bertinato, and D. Hoffmann: Synthesis and kinetics of decomposition of 7-(2-cyanoethyl)guanine and O6-(2-cyanoethyl)guanine, markers for reaction of acrylonitrile and 3-(methylnitrosamino)propionitrile with DNA; Carcinogenesis 9 (1988) 2125–2128.]Search in Google Scholar
[487. Rivenson, A., S. S. Hecht, and D. Hoffmann: Observations on lung tumors arising from metaplastic squamous epithe-lium in rats treated chronically with the tobacco-specific N-nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK); Proc. Am. Assoc. Cancer Res. 29 (1988) No. 342.]Search in Google Scholar
[488. Rivenson, A., D. Hoffmann, B. Prokopczyk, S. Amin, and S. S. Hecht: [A Study of Tobacco Carcinogenesis. XLI.] Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and areca-derived N-nitrosamines; Cancer Res. 48 (1988) 6912–6917.]Search in Google Scholar
[489. Sepkovic, D. W., N. J. Haley, and D. Hoffmann: Use of Urinary Cotinine to Estimate Exposure to Tobacco Smoke -Reply; JAMA 259 (1988) 1808–1809.]Search in Google Scholar
[490. Anderson, L. M., S. S. Hecht, D. E. Dixon, L. F. Dove, R. M. Kovatch, S. Amin, D. Hoffmann, and J. M. Rice: Evaluation of the transplacental tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice; Cancer Res. 49 (1989) 3770–3775.]Search in Google Scholar
[491. Brunnemann, K. D., R. Feng, and D. Hoffmann: Pyrolysis studies of selected nitrosamino acids in cigarettes; presented at the 43rd TCRC, Richmond, VA, 1989, No. 44.]Search in Google Scholar
[492. Brunnemann, K. D., M. R. Kagan, J. E. Cox, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXVII.] Determination of benzene, toluene and 1,3-butadiene in cigarette smoke by GC-MSD; Exp. Pathol. 37 (1989) 108–113.]Search in Google Scholar
[493. Djordjevic, M. V., C. W. Sigountos, K. D. Brunnemann, and D. Hoffmann: On the formation of 4-(methylnitrosamino)-4-(3-pyridyl) butyric acid in tobacco and tobacco smoke; presented at the 43rd TCRC, Richmond, VA, 1989, No. 27.]Search in Google Scholar
[494. Djordjevic, M. V., K. D. Brunnemann, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XLIII.] Identification and analysis of a nicotine-derived N-nitrosamino acid and other nitrosamino acids in tobacco; Carcinogenesis 10 (1989) 1725–1731.]Search in Google Scholar
[495. Haley, N. J., D. W. Sepkovic, K. D. Brunnemann, and D. Hoffmann: Biomarkers for Assessing Environmental Tobacco Smoke Update; in: Combustion Processes and the Quality of the Indoor Environment; edited by J. P. Harper, Air and Waste Management Association, Pittsburgh, PA, 1989, pp, 1–13.]Search in Google Scholar
[496. Haley, N. J., D. W. Sepkovic, and D. Hoffmann: Elimination of cotinine from body fluids: disposition in smokers and nonsmokers; Am. J. Public Health 79 (1989) 1046–1048.]Search in Google Scholar
[497. Hecht, S. S. and D. Hoffmann: The relevance of tobacco-specific nitrosamines to human cancer; Cancer Surv. 8 (1989) 273–294.]Search in Google Scholar
[498. Hoffmann, D.: Nicotine - a tobacco-specific precursor for carcinogens; in: Nicotine, Smoking, and the Low-Tar Programme; edited by N. Wald and P. Frogatt, Oxford University Press, Oxford, UK, 1989, pp. 24–40.]Search in Google Scholar
[499. Hoffmann, D., K. D. Brunnemann, and I. Hoffmann: Signifi-cance of Benzene in Tobacco Carcinogenesis; in: Benzene: Occupational and Environmental Hazards - Scientific Update; edited by M. A. Mehlman, Princeton Scientific Publ. Co., Princeton, NY, 1989, pp. 99–112.]Search in Google Scholar
[500. Hoffmann, D. and S. S. Hecht: Advances in Tobacco Carcinogenesis; in: Chemical Carcinogenesis and Mutagene-sis, Springer Handbook of Experimental Pharmacology -edited by C. S. Cooper and P. L. Grover, Springer Verlag, New York, NY, 1989, pp. 63–102.10.1007/978-3-642-74775-5_3]Search in Google Scholar
[501. Hoffmann, D. and I. Hoffmann: On the reduction of nicotine in cigarette smoke; in: Nicotine, Smoking, and the Low-Tar Programme; edited by N. Wald and P. Froggatt, Oxford University Press, Oxford, UK, 1989, pp. 200–211.]Search in Google Scholar
[502. LaVoie, E. J., P. Tucciarone, M. Kagan, J. D. Adams, and D. Hoffmann: Analysis of steam distillates and aqueous extracts of smokeless tobacco; J. Agric. Food Chem. 37 (1989) 154–157.]Search in Google Scholar
[503. Melikian, A. A., K. Bagheri, B. F. Goldin, and D. Hoffmann: Catechol-induced alterations in metabolic activation and binding of enantiomeric and racemic 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene to DNA in mouse skin; Carcinogenesis 10 (1989) 1863–1870.]Search in Google Scholar
[504. Melikian, A. A., K. Bagheri, S. S. Hecht, and D. Hoffmann: Metabolism of benzo[a]pyrene and 7-?,8-?-dihydroxy-9-?,10-?-epoxy -7,8,9,10-tetrahy dr ob en zo [a]pyrene in lung and liver of newborn mice; Chem. -Biol. Interact. 69 (1989) 245–257.]Search in Google Scholar
[505. Melikian, A. A., S. S. Hecht, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XL.] Mechanistic studies of tobacco carcinogenesis in mouse epidermis and lung tissues; in: Skin Carcinogenesis: Mechanisms and Human Rele-vance; edited by T. J. Slaga et al., A. R. Liss, Inc., New York, NY, 1989, pp. 331–345.]Search in Google Scholar
[506. Melikian, A. A., K. G. Jordan, J. Braley, J. Rigotty, C. L. Meschter, S. S. Hecht, and D. Hoffmann: Effects of catechol on the induction of tumors in mouse skin by 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrenes; Carcinogenesis 10 (1989) 1897–1900.]Search in Google Scholar
[507. Rivenson, A., M. V. Djordjevic, S. Amin, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XLIV. Bioassay in A/J mice for some N-nitrosamines; Cancer Lett. 47 (1989) 111–114.]Search in Google Scholar
[508. Brunnemann, K. D., J. E. Cox, M. R. Kagan, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XCIV.] Analysis of selected environmental tobacco smoke compo-nents in indoor air by thermal desorption-GC-MS; presented at the CORESTA Symposium, Kallithea, Greece, 1990, No. S10; in: Proc. CORESTA Symposium, Kallithea, Greece, 1990, pp. 100–107.]Search in Google Scholar
[509. Brunnemann, K. D., J. E. Cox, M. R. Kagan, and D. Hoffmann: Application of thermal desorption for the analysis of environmental tobacco smoke (ETS); presented at the 44th TCRC, Winston-Salem, NC, 1990, No. 27.]Search in Google Scholar
[510. Brunnemann, K. D. and D. Hoffmann: Analytical studies on tobacco-specific N-nitrosamines in tobacco and tobacco smoke; J. Cancer Res. Clin. Oncol. 116 (Suppl. Pt. 2) (1990) 1087.]Search in Google Scholar
[511. Brunnemann, K. D., M. R. Kagan, J. E. Cox, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXVIII.] Analysis of 1,3-butadiene and other selected gas phase components in cigarette mainstream and sidestream smoke by gas chromatography-mass selective detection; Carcinoge-nesis 11 (1990) 1863–1868.]Search in Google Scholar
[512. Djordjevic, M. V., D. Desai, C. Sigountos, K. D. Brunne-mann, and D. Hoffmann: Mechanistic studies on the formation of 4-(methylnitrosamino)-4-(3-pyridyl)butyric acid and other tobacco-specific nitrosamines during tobacco processing; presented at the 44th TCRC, Winston-Salem, NC, 1990, No. 43.10.1021/jf00001a043]Search in Google Scholar
[513. Djordjevic, M. V., C. W. Sigountos, K. D. Brunnemann, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XCIII.] Tobacco-specific nitrosamine delivery in the mainstream smoke of high- and low-yield cigarettes smoked with varying puff volumes; presented at the CORESTA Symposium, Kallithea, Greece, 1990, No. S04; in: Proc. CORESTA Symp. Kallithea, Greece, 1990, pp. 54–62.]Search in Google Scholar
[514. Haley, N. J., D. W. Sepkovic, K. D. Brunnemann, and D. Hoffmann: ETS uptake in nonsmokers after exposure to high-yield and low-yield cigarettes; in: Proceedings of the 5th International Conf. on Indoor Air Quality and Climate, Toronto, Canada, Vol. 2, 1990, pp. 183-188.]Search in Google Scholar
[515. Hoffmann, D., S. Amin, K. D. Brunnemann, B. Prokopczyk, A. Rivenson, and S. S. Hecht: Tobacco-specific N-nitros-amines: analysis, bioassays and biochemical studies; in: N-Nitroso Compounds: Biology and Chemistry; edited by S. V. Bhide and K. V. K. Rao, Omega Scientific Publishers, New Delhi, India, 1990, pp. 59-79.]Search in Google Scholar
[516. Hoffmann, D., NJ. Haley, and E. L. Wynder: [A Study of Tobacco Carcinogenesis. XLV.] Laboratory studies on the association of cigarette smoking with cancer of the uterine cervix; J. Smoking Rel. Dis. 1 (1990) 15-23.]Search in Google Scholar
[517. Melikian, A. A., K. Bagheri, and D. Hoffmann: Oxidation and DNA binding of (+)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in mouse epidermis in vivo and effects of co-administration of catechol; Cancer Res. 50 (1990) 1795-1799.]Search in Google Scholar
[518. Miyashita, M., J. C. Willey, K. Sasajima, J. F. Lechner, EJ. LaVoie, D. Hoffmann, M. Smith, B. F. Trump, and CC. Harris: Differential effects of cigarette smoke condensate and its fractions on cultured normal and malignant human bronchial epithelial cells; Exp. Pathol. 38 (1990) 19-29.]Search in Google Scholar
[519. Murphy, S. E., A. Palomino, S. S. Hecht, and D. Hoffmann: Dose response study of DNA and hemoglobin adduct formation by 4-(methylnitrosamino)-1-(3-pyridyl)-1 buta-none in F344 rats; Cancer Res. 50 (1990) 5446-5452.]Search in Google Scholar
[520. Prokopczyk, B., A. Sharma, J. E. Cox, K. D. Brunnemann, and D. Hoffmann: Application of supercritical fluid extraction for the analysis of selected components in chewing tobaccos; presented at the 44th TCRC, Winston-Salem, NC, 1990, No. 69.]Search in Google Scholar
[521. Anderson, L. M., S. S. Hecht, R. M. Kovatch, S. Amin, D. Hoffmann, and J. M. Rice: Tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in infant mice; Cancer Lett. 58 (1991) 177-181.]Search in Google Scholar
[522. Brunnemann, K. D., M. V. Djordjevic, R. Feng, and D. Hoffmann: Analysis and pyrolysis of some N-nitrosamino acids in tobacco and tobacco smoke; in: Relevance to Human Cancer of N-Nitroso Compounds, Tobacco Smoke and Mycotoxins, IARC Sci. Publ. 105 (1991) 477-481.]Search in Google Scholar
[523. Brunnemann, K. D. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XCIII.] Analytical studies on tobacco-specific N-nitrosamines in tobacco and tobacco smoke; Crit. Rev. Toxicol. 21 (1991) 235-240.]Search in Google Scholar
[524. Brunnemann, K. D. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XCVII.] Analytical studies on N-nitros-amines in tobacco and tobacco smoke; presented at the 45th TCRC, Asheville, NC, 1991, No. 3; in: Rec. Adv. Tobacco Sci. 17 (1991) 71-112.]Search in Google Scholar
[525. Brunnemann, K. D. and D. Hoffmann: Methods of analysis for tobacco-specific N-nitrosamines in indoor air; presented at the 45th TCRC, Asheville, NC, 1991, No. 50.]Search in Google Scholar
[526. Brunnemann, K. D. and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XC] Decreased concentrations of N-nitrosodiethanolamine and N-nitrosomorpholine in commer-cial tobacco products; J. Agric. Food Chem. 39 (1991) 207-208.]Search in Google Scholar
[527. Djordjevic, M. V., J. Krzeminski, K. D. Brunnemann, and D. Hoffmann: Identification and quantitative analysis of new N-nitrosamino acids in snuff tobacco; presented at the 45th TCRC, Asheville, NC, 1991, No. 16.]Search in Google Scholar
[528. Djordjevic, M. V., CM. Sigountos, K. D. Brunnemann, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. LXXXIX.] Formation of 4-(methylnitrosamino)-4-(3-pyridyl)butyric acid in vitro and in mainstream cigarette smoke; J. Agric. Food Chem. 39 (1991) 209-213.]Search in Google Scholar
[529. Djordjevic, M. V., C. W. Sigountos, D. Hoffmann, K. D. Brunnemann, M. R. Kagan, L. P. Bush, R. D. Safaev, GA. Belitsky, and D. Zaridze: Chemical Studies on Tobacco Smoke. XCI. Assessment of major carcinogens and alkaloids in the tobacco and mainstream smoke of USSR cigarettes; Int. J. Cancer 47 (1991) 348-351.]Search in Google Scholar
[530. Hecht, S. S., NJ. Haley, and D. Hoffmann: Monitoring exposure to tobacco products by measurement of nicotine metabolites and derived carcinogens; in: Molecular Dosime-try and Human Cancer: Analytical, Epidemiological, and Ethical Considerations; edited by J. D. Groopman and P. L. Skipper, CRC Press, Boca Raton, FL, 1991, pp. 325-361.]Search in Google Scholar
[531. Hecht, S. S. and D. Hoffmann: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a nicotine-derived tobacco-specific nitrosamine, and cancer of the lung and pancreas in humans; in: Origin of Human Cancer: A Comprehensive Review, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1991, pp. 745-755.]Search in Google Scholar
[532. Hecht, S. S. and D. Hoffmann: N-Nitroso compounds and tobacco-induced cancer in man; in: Relevance to Human Cancer of N-Nitroso Compounds, Tobacco Smoke and Mycotoxins, IARC Sci. Publ. 105 (1991) 54-61.]Search in Google Scholar
[533. Hoffmann, D., M. V. Djordjevic, and K. D. Brunnemann: [Chemical Studies on Tobacco Smoke. XCII.] New brands of oral snuff. (Brief Communication); Food Chem. Toxicol. 29 (1991) 65-68.]Search in Google Scholar
[534. Hoffmann, D., M. V. Djordjevic, and K. D. Brunnemann: On the control of toxic substances in smokeless tobacco; J. Smoking Related Dis. 3 (1991) 165-172.]Search in Google Scholar
[535. Hoffmann, D., NJ. Haley, M. Djordjevic, K. D. Brunnemann, and S. S., Hecht: Biomarkers of exposure to tobacco products; in: Human Carcinogen Exposure: Biomonitoring and Risk Assessment; edited by R. C Garner et al, IRL Press, Oxford, UK, 1991, pp. 275-283.]Search in Google Scholar
[536. Hoffmann, D., I. Hoffmann, and E. L. Wynder: Lung cancer and the changing cigarette; in: Relevance to Human Cancer of N-Nitroso Compounds, Tobacco Smoke and Mycotoxins; IARC Sci. Publ. 105 (1991) 449–459.]Search in Google Scholar
[537. Hoffmann, D., AA. Melikian, and K. D. Brunnemann: Studies in tobacco carcinogenesis; in: Relevance to Human Cancer of N-Nitroso Compounds, Tobacco Smoke and Mycotoxins; IARC Sci. Publ. 105 (1991) 482–484.]Search in Google Scholar
[538. Hoffmann, D., A. Rivenson, F. -L. Chung, and S. S. Hecht: Relevance of Nicotine-derived N-Nitrosamines in Tobacco Carcinogenesis; in: Effects of nicotine on biological sys-tems; edited by F. Adlkofer and K. Thurau, Birkhäuser Publ, Boston, MA, 1991, pp. 89-101.10.1007/978-3-0348-7457-1_13]Search in Google Scholar
[539. Hoffmann, D., A. Rivenson, F. -L. Chung, and S. S. Hecht: Nicotine-derived N-nitrosamines (TSNA) and their rele-vance in tobacco carcinogenesis; Crit. Rev. Toxicol. 21 (1991) 305-311.]Search in Google Scholar
[540. Matsukura, N., J. Willey, M. Miyashita, B. Taffe, D. Hoffmann, C. Waldren, T. T. Puck, and CC. Harris: Detection of direct mutagenicity of cigarette smoke condensate in mammalian cells; Carcinogenesis 12 (1991) 685-689.]Search in Google Scholar
[541. Melikian, A. A., K. Bagheri, S. S. Hecht, and D. Hoffmann: Comparative metabolism and disposition of benzo[a]pyrene and 7-|3,8-a-dihydroxy-9-a,10-a-epoxy-7,8,9,10-tetrahydro-benzo[a]pyrene in mouse epidermis and in the lungs of newborn mice in vivo; in: Polynuclear Aromatic Hydrocar-bons: Measurements, Means, and Metabolism; edited by M. Cooke et al, Battelle Press, Columbus, OH, 1991, pp. 571-581.]Search in Google Scholar
[542. Mitacek, EJ., K. D. Brunnemann, A. P. Polednak, D. Hoffmann, and M. Suttajit: [Chemical Studies on Tobacco Smoke. XCV.] Composition of popular tobacco products in Thailand, and its relevance to disease prevention; Prev. Med. 20 (1991) 764-773.]Search in Google Scholar
[543. Prokopczyk, B., D. Hoffmann, J. E. Cox, M. V. Djordjevic, and K. D. Brunnemann: Application of supercritical fluid extraction for the analysis of tobacco-specific N-nitros-amines in tobacco; presented at the 45th TCRC, Asheville, NC, 1991, No. 15.]Search in Google Scholar
[544. Prokopczyk, B., A. Rivenson, and D. Hoffmann: A Study of Betel Quid Carcinogenesis IX. Comparative carcinogenicity of 3-(methylnitrosamino)propionitrile and 4-(methylnitros-amino)-1-(3-pyridyl)-1-butanone upon local application to mouse skin and rat oral mucosa; Cancer Lett. 60 (1991) 153–157.]Search in Google Scholar
[545. Rivenson, A., S. S. Hecht, and D. Hoffmann: Carcinogenicity of tobacco-specific N-nitrosamines (TSNA): the role of the vascular network in the selection of target organs; Crit. Rev. Toxicol. 21 (1991) 255–264.]Search in Google Scholar
[546. Rivenson, A. and D. Hoffmann: Extensive spontaneous occlusive arteriosclerosis of the lingual arteries in Fischer rats, a model for the study of human occlusive arteriosclero-sis of medium- and small-sized arteries; Artery 18 (1991) 150–162.]Search in Google Scholar
[547. Sharma, A. K., B. Prokopczyk, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XCII.] Supercritical fluid extraction of moist snuff; J. Agric. Food Chem. 39 (1991) 508–510.]Search in Google Scholar
[548. Zaridze, D. G., R. D. Safaev, G. A. Belitsky, K. D. Brunne-mann, and D. Hoffmann: Carcinogenic substances in Soviet tobacco products; in: Relevance to Human Cancer of N-Nitroso Compounds, Tobacco Smoke and Mycotoxins, IARC Sci. Publ. 105 (1991) 485–488.]Search in Google Scholar
[549. Brunneman, K. D., J. E. Cox, and D. Hoffmann: [Chemical Studies on Tobacco Smoke. XCVIII.] Analysis of tobacco-specific N-nitrosamines in indoor air; Carcinogenesis 13 (1992) 2415–2418.]Search in Google Scholar
[550. Brunneman, K. D., J. E. Cox, Y. Liu, and D. Hoffmann: Analysis of volatile and tobacco-specific N-nitrosamines in tobacco smoke by conventional method and by supercritical fluid extraction; presented at the 46th TCRC, Montreal, Canada, 1992, No. 22.]Search in Google Scholar
[551. Brunnemann, K. D. and D. Hoffmann: Chemical composition of smokeless tobacco products; in: Smokeless tobacco or health: An international perspective; edited by D. R. Shop-land et al., Smoking and Tobacco Control Monogr. 2, NCI, Bethesda, MD, 1992, pp. 96–108.]Search in Google Scholar
[552. Brunnemann K. D. and D. Hoffmann: Analysis of tobacco-specific N-nitrosamines in tobacco and tobacco smoke; presented at the 204th Natl. Meeting Am. Chem. Soc., Washington, DC, 1992, No. 161.]Search in Google Scholar
[553. Brunnemann, K. D., B. Prokopczyk, M. V. Djordjevic, J. E. Cox, and D. Hoffmann: The use of supercritical fluid extraction for the analysis of tobacco-specific N-nitros-amines in tobacco and in tobacco smoke; presented at the CORESTA Congress, Jerez de la Frontera, 1992, No. ST10.]Search in Google Scholar
[554. Brunnemann, K. D., A. Rivenson, S. C. Cheng, V. Saa, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XLVII. Bioassays of vinylpyridines for genotoxicity and for tumori-genicity in A/J mice; Cancer Lett. 65 (1992) 107–113.]Search in Google Scholar
[555. Djordjevic, M. V., K. D. Brunnemann, and D. Hoffmann: The occurence of N-nitrosamino acids in commercial tobacco products and effect of storage conditions on their levels; presented at the 46th TCRC, Montreal, Canada, 1992, No. 23.]Search in Google Scholar
[556. Djordjevic, M. V., D. Hoffmann, K. D. Brunnemann, L. P. Bush: Effect of storage conditions on the levels of tobacco-specific nitrosamines, alkaloids and nitrite in US commer-cial moist snuff; presented at the CORESTA Congress, Jerez de la Frontera, 1992, No. ST17.]Search in Google Scholar
[557. Djordjevic, M. V., J. Krzeminski, K. D. Brunnemann, and D. Hoffmann: Characterization of N-nitrosamino acids in tobacco products and assessment of their carcinogenic potential; presented at the 204th Natl. Meeting, Am. Chem. Soc., Washington, DC, 1992, No. 160.]Search in Google Scholar
[558. Hoffmann, D., K. D. Brunnemann, I. Hoffmann, A. Riven-son, and S. S. Hecht: Advances in Tobacco Carcinogenesis. II. Cigarette smoke; in: Control of Tobacco-related Cancers and Other Diseases; edited by P. C. Gupta et al, Oxford University Press, Bombay, India, 1992, pp. 205-216.]Search in Google Scholar
[559. Hoffmann, D., S. S. Hecht, and E. L. Wynder: Cancer of the upper aerodigestive tract: environmental factors and prevention; J. Tobacco Rel. Dis. 3 (1992) 109-129.]Search in Google Scholar
[560. Hoffmann, D., A. Rivenson, and S. S. Hecht: Carcinogenesis of Smokeless Tobacco; in: Smokeless tobacco or health: An international perspective; edited by D. R. Shopland et al, Smoking and Tobacco Control Monogr. 2, NCI, Bethesda, MD, 1992, pp. 109-118.]Search in Google Scholar
[561. Hoffmann, D., A. Rivenson, B. Prokopczyk, K. D. Brunne-mann, S. G. Carmella, and I. Hoffmann: Advances in Tobacco Carcinogenesis I. Smokeless tobacco and betel quid; in: Control of Tobacco-Related Cancers and Other Diseases; edited by P. C. Gupta et al, Oxford University Press, Bombay, India, 1992, pp. 193-204.]Search in Google Scholar
[562. Hoffmann, D., A. Rivenson, E. L. Wynder, and S. S. Hecht: Formation of tobacco-specific N-nitrosamines, their carcino-genicity, and the role of dietary fat in their carcinogenicity; presented at the 204th Natl. Meeting, Am. Chem. Soc, Washington, DC, 1992, No. 119.]Search in Google Scholar
[563. Koppang, N., A. Rivenson, A. Reith, H. K. Dahle, Ö. Eversen, and D. Hoffmann: A Study of Tobacco Carcinogenesis. XLVIII. Carcinogenicity of N’-nitrosonornico-tine in mink (Mustela vison); Carcinogenesis 13 (1992) 1957-1960.]Search in Google Scholar
[564. Murphy, S. E., S. Amin, K. Coletta, and D. Hoffmann: Rat liver metabolism of benzo[b]naphtho[2,1-d]thiophene; Chem. Res. Toxicol. 5 (1992) 491–495.]Search in Google Scholar
[565. Nishikawa, A., B. Prokopczyk, A. Rivenson, E. Zang, and D. Hoffmann: A Study of Betel Quid Carcinogenesis VIII. Carcinogenicity of 3-(methylnitrosamino)propionaldehyde in F344 rats; Carcinogenesis 13 (1992) 369-372.]Search in Google Scholar
[566. Prokopczyk, B., D. Hoffmann, J. E. Cox, M. V. Djordjevic, and K. D. Brunnemann: [Chemical Studies on Tobacco Smoke. XCVI.] Supercritical fluid extraction in the determi-nation of tobacco-specific N-nitrosamines in smokeless tobacco; Chem. Res. Toxicol. 5 (1992) 336-340.]Search in Google Scholar
[567. Prokopczyk, B., M. Wu, J. E. Cox, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XLVI.] Bioavailability of tobacco-specific N-nitrosamines to the snuff dipper; Carcinogenesis 13 (1992) 863-866.]Search in Google Scholar
[568. Safaev, R., G. A. Belitskii, TA. Licheva, I. A. Khitrovo, S. Y. Fukhs, L. V. Krivosheyeva, D. Hoffmann, K. D. Brunnemann, and M. V. Djordjevic: The effect of cigarette filter modification on the content of chemical carcinogens in cigarette smoke and genotoxicity of condensate; Eksp. Onkol. 14 (1992) 24-27.]Search in Google Scholar
[569. Safaev, R., D. G. Zaridze, G. A. Belitskii, M. V. Djordjevic, D. Hoffmann, K. D. Brunnemann, Y. A. Perezhogina, N. N. Sokolskaya, A. Goginasvili, and Y. Khesina: Carcinogenic substances in the tobacco and smoke of cigarettes: Polynuclear aromatic hydrocarbons, metals, pesticides; Eksp. Onkol. 14 (1992) 25-29.]Search in Google Scholar
[570. Brunnemann, K. D., J. E. Cox, and D. Hoffmann: Determination of cadmium in cigarette smoke and its possible role as biomarker; presented at the 47th TCRC, Gatlinburg, TN, 1993, No. 20.]Search in Google Scholar
[571. Djordjevic, M. V., K. D. Brunnemann, and D. Hoffmann: The need for regulation of carcinogenic N-nitrosamines in oral snuff; Food Chem. Toxicol. 31 (1993) 497-501.]Search in Google Scholar
[572. Djordjevic, M. V., J. Fan, K. D. Brunnemann, and D. Hoffmann: In vitro nitrosation of nicotine and some of its metabolites under phy siological conditions; presented at the 47th TcRC, Gatlinburg, TN, 1993, No. 12.]Search in Google Scholar
[573. Djordjevic, M. V., J. Fan, L. P. Bush, K. D. Brunnemann, and D. Hoffmann: Effects of storage conditions on levels of tobacco-specific N-nitrosamines and N-nitrosamino acids in US moist snuff; J. Agric. Food, Chem. 41(1993) 1790-1794.]Search in Google Scholar
[574. Hecht, S. S., S. G. Carmella, S. E. Murphy, S. Akerkar, K. D. Brunnemann, and D. Hoffmann: A Tobacco-specific Lung Carcinogen in the Urine of Men Exposed to Cigarette Smoke; New Engl. J. Med. 329 (1993) 1543-1546.]Search in Google Scholar
[575. Hoffmann, D.: Analysis of toxic smoke constituents; in: U. S. Consumer Product Safety Commission. Fire Safe Cigarette Act of 1990. Toxicity Testing. Vol. 5; edited by B. C. Lee, Washington, DC, 1993, pp. D1-D38.]Search in Google Scholar
[576. Hoffmann, D: In vivo bioassays for carcinogenicity. U. S. Consumer Product Safety Commission. Fire Safe Cigarette Act of 1990. Toxicity Testing. Vol. 5; edited by B. C. Lee, Washington, DC, 1993, pp. F1-F17.]Search in Google Scholar
[577. Hoffmann, D., M. V. Djordjevic, A. Rivenson, E. Zang, D. Desai, and S. Amin: A Study of Tobacco Carcinogenesis. LI. Relative potencies of tobacco-specific N-nitrosamines as inducers of lung tumors in A/J mice; Cancer Lett. 71 (1993) 25-30.]Search in Google Scholar
[578. Hoffmann, D. and I. Hoffmann: Tobacco smoke as a respiratory carcinogen; in: Prevention of Respiratory Disease; edited by A. Hirsch et al., Marcel Dekker Inc., New York, NY, Vol. 68, 1993, pp. 497-532.]Search in Google Scholar
[579. Hoffmann, D., A. Rivenson, R. Abbi, and E. L. Wynder: A Study of Tobacco Carcinogenesis [L.]: Effect of the fat content of the diet on the carcinogenic activity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in F344 rats; Cancer Res. 53 (1993) 2758-2761.]Search in Google Scholar
[580. Hoffmann, D., A. Rivenson, F. -L. Chung, and E. L. Wynder: Potential inhibitors of tobacco carcinogenesis; Ann. NY Acad. Sci. 686 (1993) 140-160.]Search in Google Scholar
[581. Hoffmann, D., A. Rivenson, S. E. Murphy, F. -L. Chung, S. Amin, and S. S. Hecht: Cigarette smoking and adenocarci-noma of the lung: the relevance of nicotine-derived N-nitrosamines; J. Smoking Related Dis. 4 (1993) 165-189.]Search in Google Scholar
[582. Melikian, AA., A. K. Prahalad, and D. Hoffmann: [A Study of Tobacco Carcinogenesis. XLIX.] Urinary trans, trans-muconic acid as an indicator of exposure to benzene in cigarette smokers; Cancer Epidemiol. Biomarkers Prev. 2 (1993) 47-51.]Search in Google Scholar
[583. Brunnemann, K. D. and D. Hoffmann: Analysis of tobacco-specific nitrosamines in tobacco and tobacco smoke; in: Nitrosamines and Related N-Nitroso Compounds. Chemistry and Biochemistry; edited by R. N. Loeppky and CJ. Michejda, Am. Chem. Soc. Monogr. 553 (1994) 369-371.]Search in Google Scholar
[584. Brunnemann, K. D. and D. Hoffmann: Analysis of selected mainstream smoke components of low ignition propensity cigarettes; presented at the 48th TCRC, Greenboro, NC, 1994, No. 54.]Search in Google Scholar
[585. Brunnemann, K. D., D. Hoffmann, CG. Gairola, and B. C. Lee: [Chemical Studies on Tobacco Smoke. XCIX.] Low ignition propensity cigarettes: smoke analysis for carcino-gens and testing for mutagenic activity of the smoke particu-late matter; Food Chem. Toxicol. 32 (1994) 917-922.]Search in Google Scholar
[586. Djordjevic, M. V., J. Fan, and D. Hoffmann: Chlorinated pesticide residues in tobacco products: analysis based on supercritical fluid extraction; presented at the 48th TCRC, Greenboro, NC, 1994, No. 49.]Search in Google Scholar
[587. Djordjevic, M. V., J. Fan, J. Krzeminski, K. D. Brunnemann, and D. Hoffmann: Characterization of N-nitrosamino acids in tobacco products and assessment of their carcinogenic potential; in: Nitrosamines and Related N-Nitroso Compounds. Chemistry and Biochemistry; edited by R. N. Loeppky and CJ. Michejda, Am. Chem. Soc. Monogr. 553 (1994) 367-368.]Search in Google Scholar
[588. Djordjevic, M. V., D. Hoffmann, J. Fan, B. Prokopczyk, M. L. Citron, and S. D. Stellman: Assessment of chlorinated pesticide and polychlorinated biphenols in adipose breast tissue using a supercritical fluid extraction method; Carcinogenesis 15 (1994) 2581-2585.]Search in Google Scholar
[589. Hecht, S. S., S. E. Murphy, and D. Hoffmann: Tobacco-specific lung carcinogen and exposure to passive smoking; New Eng. J. Med. 330 (1994) 1016–1017.]Search in Google Scholar
[590. Hoffmann, D., K. D. Brunnemann, B. Prokopczyk, and M. V. Djordjevic: Tobacco-specific N-nitrosamines and areca-derived N-nitrosamines: chemistry, biochemist ry, carcinoge-nicity and relevance to humans; J. Toxicol. Environ. Health 41 (1994) 1–52.]Search in Google Scholar
[591. Hoffmann, D. and I. Hoffmann: Recent developments in smoking related cancer research; J. Smoking Rel. Disord. 5 (1994) 77–93.]Search in Google Scholar
[592. Hoffmann, D. and I. Hoffmann: Tobacco Consumption and Lung Cancer; in: Lung Cancer. V. Advances in Basic and Clinical Research; edited by H. H. Hansen, Kluwer Aca-demic Publ., Boston, MA, 1994, pp. 1–42.10.1007/978-1-4615-2630-8_1]Search in Google Scholar
[593. Hoffmann, D., A. Rivenson, E. L. Wynder, and S. S. Hecht: Formation of tobacco-specific nitrosamines: Carcinogenic-ity, and the role of dietary fat in their carcinogenicity; in: Nitrosamines and Relat ed N- N it roso Compounds. Chemistry and Biochemistry; edited by R. N. Loeppky and C. J. Michejda, Am. Chem. Soc. Monogr. 553 (1994) 267–278.]Search in Google Scholar
[594. Hoffmann, D. and E. L. Wynder: Aktives und Passives Rauchen [Active and passive smoking]; in: Lehrbuch der Toxikologie; edited by H. Marquardt and S. G. Schaefer, B. I. Wissenschaftsverlag, Mannheim, Germany, 1994, pp. 589–605.]Search in Google Scholar
[595. Idris, A. M., B. Prokopczyk, and D. Hoffmann: Toombak: a major risk factor for cancer of the oral cavity in Sudan; Prev. Med. 23 (1994) 832–839.]Search in Google Scholar
[596. Murphy, S. E., S. G. Carmella, A. M. Idris, and D. Hoffmann: Uptake and metabolism of carcinogenic levels of tobacco-specific nitrosamines by Sudanese snuff dippers; Cancer Epidemiol. Biomarkers Prev. 3 (1994) 423–428.]Search in Google Scholar
[597. Prokopczyk, B., J. Krzeminski, and D. Hoffmann: Signifi-cance of nitrosamines in betel quid carcinogenesis; in: Nitrosamines and Related N-Nitroso Compounds. Chemistry and Biochemistry; edited by R. N. Loeppky and C. J. Michejda, Am. Chem. Soc. Monogr. 553 (1994) 365–366.]Search in Google Scholar
[598. Prokopczyk, B., M. Wu, J. E. Cox, S. Amin, D. Desai, and D. Hoffmann: The application of supercritical fluid extraction (SFE) for the determination of tobacco-specific nitrosamines in various tobacco samples. II. Optimization of the method-ology; presented at the 48th TCRC, Greensboro, NC, 1994, No. 45.]Search in Google Scholar
[599. Wynder, E. L. and D. Hoffmann: Smoking and lung cancer: Scientific challenges and opportunities; Cancer Res. 54 (1994) 5284–5295.]Search in Google Scholar
[600. Djordjevic, M. V., J. Fan, S. Ferguson, and D. Hoffmann: Self-regulation of smoking intensity. Smoke yields of the low-nicotine, low-“tar” cigarettes; Carcinogenesis 16 (1995) 2015–2021.]Search in Google Scholar
[601. Djordjevic, M. V., J. Fan, S. Ferguson, and D. Hoffmann: The chemical composition of mainstream cigarette smoke generated under FTC/CORESTA and actual human smoking (AHS) conditions; presented at the CORESTA Meet. Smoke-Techno Groups, Vienna, Austria, 1995, No. ST22.]Search in Google Scholar
[602. Djordjevic, M. V., J. Fan, and D. Hoffmann: Assessment of chlorinated pesticide residues in cigarette tobacco based on supercritical fluid extraction and GC-ECD; Carcinogenesis 16 (1995) 2627–2632.]Search in Google Scholar
[603. Djordjevic, M. V. and D. Hoffmann: Nicotine, pH, and N-nitrosamines in US commercial moist snuff brands; pre-sented at the 49th TCRC, Lexington, KY, 1995, No. 35.]Search in Google Scholar
[604. Djordjevic, M. V., D. Hoffmann, T. Glynn, and G. N. Con-nolly: US commercial brands of moist snuff, 1994. I. Assessment of nicotine, moisture, and pH; Tob. Control 4 (1995) 62–66.]Search in Google Scholar
[605. Hoffmann, D., M. V. Djordjevic, and K. D. Brunnemann: Changes in cigarette design and composition over time and how they influence the yields of smoke constituents; J. Smoking Rel. Disord. 6 (1995) 9–23.]Search in Google Scholar
[606. Hoffmann, D., M. V. Djordjevic, J. Fang, E. Zang, T. Glynn, and G. C. Connolly: Five leading US commercial brands of moist snuff in 1994: assessment of carcinogenic N-nitros-amines; J. Natl. Cancer Inst. 87 (1995) 1862–1869.]Search in Google Scholar
[607. Hoffmann, D. and I. Hoffmann: Tobacco consumption and lung cancer; Cancer Treat Res. 72 (1995) 1–42.]Search in Google Scholar
[608. Muscat, J. E., D. Hoffmann, and E. L. Wynder: The epidemi-ology of renal cell carcinoma: a second look; Cancer 75 (1995) 2552–2557.]Search in Google Scholar
[609. Prokopczyk, B, J. E. Cox, D. Pullo, and D. Hoffmann: GC-SRM-MS/MS for the analysis of TSNA in biological samples; presented at the 49th TCRC, Lexington, KY, 1995, No. 36.]Search in Google Scholar
[610. Prokopczyk, B., M. Wu, S. Amin, D. Desai, A. M. Idris, and D. Hoffmann: Improved methodology for the quantitative assessment of tobacco-specific N-nitrosamines in tobacco by supercritical fluid extraction; J. Agric. Food Chem. 43 (1995) 916–922.]Search in Google Scholar
[611. Safaev, R. D., D. G. Zaridze, D. Hoffmann, K. D. Brunne-mann, and Y. Liu: Efficiency and assessment of new cigarette filters. Chemical analysis of some of the toxic and carcinogenic agents in the mainstream smoke; Exper. Oncol. 17 (1995) 71–76.]Search in Google Scholar
[612. Amin, S., D. Desai, S. S. Hecht, and D. Hoffmann: Synthesis of tobacco-spec ific N-ni tr osamin es and their metabolites and results of related bioassays; Crit. Rev. Toxicol. 26 (1996) 139–147.]Search in Google Scholar
[613. Brunnemann, K. D., B. Prokopczyk, M. V. Djordjevic, and D. Hoffmann: Formation and analysis of tobacco-specific N-nitrosamines; Crit. Rev. Toxicol. 26 (1996) 121–137.]Search in Google Scholar
[614. Djordjevic, M. V., L. Eixarch, L. P. Bush, and D. Hoffmann: A comparison of the yields of selected components in the mainstream smoke of the leading US and Japanese ciga-rettes; presented at the CORESTA Congress Yokohama, Japan, 1996, No. S10; in: CORESTA Proc. Joint Smoke-Technology Groups, Yokohama, Japan, 1996, pp. 200–217.]Search in Google Scholar
[615. Djordjevic, M. V., J. Fan, S. Akerkar, J. Heidbrink, J. P. Richie Jr, and D. Hoffmann: Effects of smokers’ compen-sation for nicotine on mainstream smoke chemistry and urinary biomarkers of exposure; presented at the 50th TCRC, Richmond, VA, 1996, No. 64.]Search in Google Scholar
[616. El-Bayoumy, K., B. Prokopczyk, L. A. Peterson, D. Desai, S. Amin, B. S. Reddy, D. Hoffmann, and E. L. Wynder: Effects of dietary fat content on the metabolism of NNK and on DNA methylation induced by NNK; Nutr. Cancer, 26 (1996) 1–10.]Search in Google Scholar
[617. El-Bayoumy, K., P. Upadhyaya, D. H. Desai, S. Amin, D. Hoffmann, and E. L. Wynder: Effects of 1,4-phenylenebis-(methylene)selenocyanate, phenylethyl isothiocyanate, in-dole-3-carbinol, and d-limonene individually and in combi-nation on the tumorigenicity of the tobacco-specific nitros-amine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung; Anticancer Res. 16 (1996) 2709–2712.]Search in Google Scholar
[618. Hoffmann, D., M. V. Djordjevic, and K. D. Brunnemann: Changes in cigarette design and composition over time and how they influence the yields of smoke constituents; in: The FTC cigarette test method for determining tar, nicotine, and carbon monoxide yields of US cigarettes; NIH/NCI. Smoking and Tobacco Control Monogr. 7, NCI, Bethesda, MD, 1996, pp. 15–37.]Search in Google Scholar
[619. Hoffmann, D., A. A. Melikian, and E. L. Wynder: Scientific challenges in environmental carcinogenesis; Prev. Med. 25 (1996) 14–22.]Search in Google Scholar
[620. Hoffmann, D., A. Rivenson, and S. S. Hecht: The biological significance of tobacco-specific N-nitrosamines: smoking and adenocarcinoma of the lung; Crit. Rev. Toxicol. 26 (1996) 199–211.]Search in Google Scholar
[621. Lazarus, P., A. M. Idris, J. Kim, A. Calcagnotto, and D. Hoffmann: p53 mutations in head and neck squamous carcinomas from Sudanese snuff (Toombak) users; Cancer Detect. Prev. 20 (1996) 270-278.]Search in Google Scholar
[622. Prokopczyk, B., J. E. Cox, P. Upadhyaya, S. Amin, D. Desai, D. Hoffmann, and K. El-Bayoumy: Effects of dietary 1,4-phenylenebis(methylene)selenocyanate on 4-(methyl-nitrosamino)-1-(3-pyridy l)-1 -butanone-induced DNA adduct formation in lung and liver of A/J mice and F-344 rats; Carcinogenesis 17 (1996) 749-753.]Search in Google Scholar
[623. Djordjevic, M. V., L. Eixarch, and D. Hoffmann: Self-administered and effective dose of cigar smoke constituents; pres. at the 51st TCRC, Winston-Salem, NC, 1997, No. 9.]Search in Google Scholar
[624. Djordjevic, M. V., D. Hoffmann, S. Thompson, and S. D. Stellman: Distribution of smoking parameters and self-administered doses of select smoke components among different population groups; presented at the CORESTA Meet. Smoke-Techno Groups, Hamburg, 1997, No. ST7; in: CORESTA Proc. Smoke-Techno Groups, Hamburg, Germany, 1997, pp. 44-61.]Search in Google Scholar
[625. Djordjevic, M. V., D. Hoffmann, and I. Hoffmann: Nicotine regulates smoking patterns; Prev. Med. 26 (1997) 435–440.]Search in Google Scholar
[626. Hoffmann, D. and M. V. Djordjevic: Chemical composition and carcinogenicity of smokeless tobacco; Adv. Dental Res. 11 (1997) 322-329.]Search in Google Scholar
[627. Hoffmann, D., M. V. Djordjevic, and I. Hoffmann: The changing cigarette; Prev. Med. 26 (1997) 427–434.10.1006/pmed.1997.0183]Search in Google Scholar
[628. Hoffmann, D. and I. Hoffmann: [Chemical Studies on Tobacco Smoke. C] The changing cigarette, 1950-1995. J. Toxicol Environ. Health 50 (1997) 307-364.]Search in Google Scholar
[629. Hoffmann, D. and E. L. Wynder: Tobacco smoke; in: Ency clopaedia of Occupational Health and Safety; edited by J. Majer Stellman, ICLO Publications, Geneva, Switzerland. Vol. 2, 1997, pp. 44. 11–44. 14.]Search in Google Scholar
[630. Koppang, N., A. Rivenson, H. K. Dahle, and D. Hoffmann: A Study of Tobacco Carcinogenesis. LIII. Carcinogenicity of N’-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in mink (Mustala vison); Cancer Lett. 111 (1997) 167-171.]Search in Google Scholar
[631. Muscat, J. E., S. D. Stellman, D. Hoffmann, and E. L. Wynder: Smoking and pancreatic cancer in men and women; Cancer Epidemiol. Biomarkers Prev. 6 (1997) 15-19.]Search in Google Scholar
[632. Prokopczyk, B., J. E. Cox, D. Hoffmann, and S. E. Waggoner: Identification of tobacco-specific carcinogen in the cervical mucus of smokers and nonsmokers; J. Natl. Cancer Inst. 89 (1997) 868-873.]Search in Google Scholar
[633. Stellman, S. D., J. E. Muscat, D. Hoffmann, and E. L. Wynder: Impact of filter cigarette smoking on lung cancer histology; Prev. Med. 26 (1997) 451–456.]Search in Google Scholar
[634. Stellman, S. D., J. E. Muscat, S. Thompson, D. Hoffmann, and E. L. Wynder: Risk of squamous cell carcinoma and adenocarcinoma of the lung in relation to lifetime filter cigarette smoking; Cancer 80 (1997) 382-388.]Search in Google Scholar
[635. Burnes, D. M., D. Hoffmann, and K. M. Cummings (Edi-tors): Cigar Smoking in the United States; NIH/NCI Smoking and Tobacco Control Monogr. 9, NCI, Bethesda, MD, 1998.]Search in Google Scholar
[636. Djordjevic, M. V., D. Hoffmann, S. Thompson, and S. D. Stellman:. Tobacco and mainstream smoke chemistry of the leading U. S. and Japanese cigarettes; presented at the 52nd Tobacco Science Research Conference (TSRC), Atlanta, GA, 1998, No. 59.]Search in Google Scholar
[637. Djordjevic, M. V., D. Hoffmann, S. Thompson, and S. D. Stellman: Smoking behavior and exposure to selected toxic agents among smokers of low- and medium-y ield cigarettes; presented at the CORESTA Congress Brighton, UK, 1998, No. ST16.]Search in Google Scholar
[638. Hecht, S. S. and D. Hoffmann: N-Nitroso compounds and man: sources of exposure, endogenous formation, and occurrence in body fluids; [Correspondence] Europ. J. Cancer Prev. 7 (1998) 165-166.]Search in Google Scholar
[639. Hoffmann, D. and I. Hoffmann: Letter to the Editor: Tobacco Smoke Components; Beitr. Tabakforsch. Int. 18 (1998) 49-52.]Search in Google Scholar
[640. Hoffmann, D. and I. Hoffmann: Chemistry and Toxicology; in: Cigar Smoking in the United States; edited by D. M. Burnes et al., Smoking and Tobacco Control Monograph 9, NCI, Bethesda, MD, 1998, pp. 55-104.]Search in Google Scholar
[641. Hoffmann, D., I. Hoffmann, and E. L. Wynder: The changing cigarette, 1950-1997: facts and expectations; in: Proc. Canadian Conf. of Cigarette Toxicity Reduction; edited by W. S. Rickert, Toronto, Canada, 1998, 94 p.]Search in Google Scholar
[642. Prokopczyk, B., D. Hoffmann, N. Trushin, J. E. Cox, K. El-Bayoumi, and S. Waggoner: In vitro studies on the metabo-lism of NNK in cervical tissue; presented at the 52nd TSRC, Atlanta, GA, 1998, No. 63.]Search in Google Scholar
[643. Wynder, E. L. and D. Hoffmann: Re: Cigarette Smoking and the Histopathology of Lung Cancer J. Natl. Cancer Inst. 90 (1998) 1486-1487.]Search in Google Scholar
[644. El-Bayoumy, K. and D. Hoffmann: Nutrition and tobacco-related cancer; in: Nutritional Oncology; edited by D. Heber et al., Academic Press, San Diego, CA, 1999, pp. 299-324.]Search in Google Scholar
[645. El-Bayoumy, K., M. Iatropoulos, S. Amin, D. Hoffmann, and E. L. Wynder: Increased expression of cyclooxygenase-2 in rat lung tumors induced by the tobacco-specific nitros-amine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: the impact of a high-fat diet; Cancer Res. 59 (1999) 1400-1403.]Search in Google Scholar
[646. Hoffmann, D., S. Amin, K. D. Brunnemann, D. Desai, and A. C. Collins: On the modulation of nicotine: Studies on 2-methylnicotine; presented at the 53rd TSRC, Montreal, Canada, 1999, No. 29.]Search in Google Scholar
[647. Hoffmann, D. and I. Hoffmann: (Obituary) Ernst L. Wynder, MD, Dr Sc hc (mult) Dr med hc, 1922-1999; Tobacco Control 8 (1999) 444–445.]Search in Google Scholar
[648. Hoffmann, D. and E. L. Wynder: Active and Passive Smoking; in: Toxicology; edited by H. Marquardt et al, Academic Press, San Diego, CA, 1999, pp. 879-898.10.1016/B978-012473270-4/50095-X]Search in Google Scholar
[649. Kagan, M. R., J. A. Cunningham, and D. Hoffmann: Propyl-ene glycol: a precursor of propylene oxide in cigarette smoke; presented at the 53rd TSRC, Montreal, Canada, 1999, No. 41.]Search in Google Scholar
[650. Melikian, AA., P. Sun, B. Prokopczyk, K. El-Bayoumy, D. Hoffmann, X. Wang, and S. Waggoner: Identification of benzo[a]pyrene metabolites in cervical mucus and DNA adducts in cervical tissues in humans by gas chroma-tography-mass spectrometry; Cancer Lett. 146 (1999) 127-134.]Search in Google Scholar
[651. Melikian, AA., X. Wang, S. Waggoner, D. Hoffmann, and K. El-Bayoumy: Comparative response of normal and of human papillomavirus-16 immortalized human epithelial cervical cells to benzo[a]pyrene; Oncol. Rep. 6 (1999) 1371-1376.]Search in Google Scholar
[652. Mitacek, EJ., K. D. Brunnemann, D. Hoffmann, T. Limsila, M. Suttajit, N. Martin, and L. S. Caplan: [Chemical Studies on Tobacco and Tobacco Smoke. CI.] Volatile nitrosamines and tobacco-specific nitrosamines in the smoke of Thai cigarettes: a risk factor for lung cancer and a suspected risk factor for liver cancer in Thailand; Carcinogenesis 20 (1999) 133-137.]Search in Google Scholar
[653. Baker, F., S. R. Ainsworth, J. T. Dye, C. Crammer, M. J. Thun, D. Hoffmann, J. L. Repace, J. E. Henningfield, J. Slade, J. Pinney, T. Shanks, D. M. Burns, G. N. Connolly, and D. R. Shopland: Health risks associated with cigar smoking; JAMA 284 (2000) 735-740.]Search in Google Scholar
[654. Brunnemann, K. D., J. Qi, and D. Hoffmann: Analytical comparison of two types of oral snuff; presented at the 54th TSRC, Nashville, TN, 2000, No. 40.]Search in Google Scholar
[655. Hecht, S. S. and D. Hoffmann: Re: Cigar smoking in men and risk of death from tobacco-related cancers; J. Natl. Cancer Inst. 92 (2000) 2040 [Comment on Shapiro et al.: J. Natl. Cancer Inst. 92 (2000) 333–337 and Boffetta et al.: J. Natl. Cancer Inst. 91 (1999) 697–701].]Search in Google Scholar
[656. Hoffmann, D. and I. Hoffmann: Ernst L. Wynder, M. D., Dr. Sc. h. c. (Mult.), Dr. med. h. c. - 1922–1999. Ein Nachruf; Soz. Präventivmed. 45 (2000) 61–63.]Search in Google Scholar
[657. Brunnemann, K. D., J. Qi, L. P. Bush, and D. Hoffmann: Alkaloid profile in oral moist snuff tobacco; presented at the 55th TSRC, Greensboro, NC, 2001, No. 41.]Search in Google Scholar
[658. Brunnemann, K. D., J. Qi, G. N. Connolly, and D. Hoffmann: Effects of storage on the levels of tobacco specific nitros-amines in oral moist snuff tobacco; presented at the 55th TSRC, Greensboro, NC, 2001, No. 40.10.1016/S0278-6915(02)00134-5]Search in Google Scholar
[659. Brunnemann, K. D, J. Qi, and D. Hoffmann: Aging of Oral Moist Snuff and the Yields of Tobacco-Specific N-Nitros-amines (TSNA); Progress Report, prepared for the Massachusetts Tobacco Control Program, Department of Public Health, Boston, MA, American Health Foundation, Valhalla, NY, 2001.]Search in Google Scholar
[660. Hoffmann, D. and I. Hoffmann: The Changing Cigarette. Chemical studies and bioassays; in: Risks Associated with Smoking Cigarettes with Low-Machine-Measured Yields of Tar and Nicotine. Smoking and Tobacco Control Monogr. 13, NCI, Bethesda, MD, 2001, pp. 159–191.]Search in Google Scholar
[661. Hoffmann, D., I. Hoffmann, and K. El-Bayoumy: The less harmful cigarette: a controversial issue. A tribute to Ernst L. Wynder; Chem. Res. Toxicol. 14 (2001) 767–790.]Search in Google Scholar
[662. Brunnemann, K. D., J. Qi, and D. Hoffmann: Chemical profile of two types of oral snuff tobacco; Food Chem. Toxicol. 40 (2002) 1699–1703.]Search in Google Scholar
[663. Prokopczyk, B., D. Hoffmann, M. Bologna, A. J. Cunning-ham, N. Trushin, S. Akerkar, T. Boyiri, S. Amin, D. Desai, S. Colosimo, B. Pittman, G. Leder, M. Ramadani, D. Henne-Bruns, H. G. Beger, and K. El-Bayoumy: Identification of tobacco-derived compounds in human pancreatic juice; Chem. Res. Toxicol. 15 (2002) 677–685.]Search in Google Scholar
[664. Brunnemann, K. D. J. Qi, and D. Hoffmann: Extraction of nicotine and TSNA from moist snuff by snuff dippers; presented at the 57th TSRC, Norfolk, VA, 2003, No. 20.]Search in Google Scholar
[665. Melikian, A. A., J. Hosey, J. Zhang, S. Colosimo, D. Hoffmann, M. Varga, J. H. Jaffe, and W. B. Barr: Reduction of urinary metabolites of tobacco carcinogens in smokers who switched from conventional light cigarettes to a new ciga-rette with low levels of tobacco-specific nitrosamines and a modified filter tip; in: Proc. Am. Assoc. Cancer Res., 2003, No. 6414.]Search in Google Scholar
[666. Brunnemann, K. D., J. Qi, and D. Hoffmann: Levels of TSNA in oral moist snuff in the past 30 years and today; presented on the 58th TSRC, Winston-Salem, NC, 2004, No. 38.]Search in Google Scholar
[667. El-Bayoumy, K., J. E. Muscat, and D. Hoffmann: Nutrition and tobacco-related cancer; in: Nutritional Oncology. (2nd Edition); edited by G. I. Blackburn et al., Academic Press, San Diego, CA, 2006, pp. 199–218.10.1016/B978-012088393-6/50066-X]Search in Google Scholar
[668. Trushin, N., G. Leder, K. El-Bayoumy, D. Hoffmann, H. G. Beger, D. Henne-Bruns, M. Ramadani, B. Prokopczyk: The tobacco carcinogen NNK is stereoselectively reduced by human pancreatic microsomes and cytosols; Langenbecks Arch. Surg. 393 (2008) 571–579.]Search in Google Scholar
[669. Melikian, A. A. and D. Hoffmann: Smokeless tobacco: a gateway to smoking or a way away from smoking; presented at the Symposium for Aerosol Dynamics & Health, 2008, Cardiff University School of Biosciences, Wales, UK, Biomarkers, 14 Suppl. 1 (2009) 85–89.]Search in Google Scholar
[670. Schwartz, J. L, K. D. Brunnemann, A. J. Adami, S. Panda, S. C. Gordon, D. Hoffmann, G. R. Adami: Brand specific responses to smokeless tobacco in a rat lip canal model. J. Oral Pathol. Med. 39 (2010) 453–459.]Search in Google Scholar
