<abstract xmlns="http://www.w3.org/1999/xhtml"><p> The influence of tobacco phytosterols (cholesterol, campesterol, stigmasteroI, b-sitosterol) on the chemical composition and biologicaI activity of tobacco smoke has been of concern to tobacco chemists. Therefore, a relatively simple method, utilizing a 14C-internal standard, chromatography on Sephadex and gas-liquid chromatography, was developed for the quantitative analysis of the phytosterols; this method was applied to the tobacco and smoke (mainstream and sidestream) of cigarettes and cigars to determine the fate of the phytosterols in burning tobacco. About 20 % of the total phytosterol content of tobacco was shown to be transferred intact into the smoke; about 2 % was possibly converted into polynuclear aromatic hydrocarbons. Radioactive tracer and pyrolysis studies were used to determine the nature of the phytosterol degradation products found in the smoke. </p></abstract>

The influence of tobacco phytosterols (cholesterol, campesterol, stigmasteroI, b-sitosterol) on the chemical composition and biologicaI activity of tobacco smoke has been of concern to tobacco chemists. Therefore, a relatively simple method, utilizing a 14C-internal standard, chromatography on Sephadex and gas-liquid chromatography, was developed for the quantitative analysis of the phytosterols; this method was applied to the tobacco and smoke (mainstream and sidestream) of cigarettes and cigars to determine the fate of the phytosterols in burning tobacco. About 20 % of the total phytosterol content of tobacco was shown to be transferred intact into the smoke; about 2 % was possibly converted into polynuclear aromatic hydrocarbons. Radioactive tracer and pyrolysis studies were used to determine the nature of the phytosterol degradation products found in the smoke.

Phytosterols in Tobacco: Quantitative Analysis and Fate in Tobacco Combustion

Division of Environmental Carcinogenesis, Naylor Dana Institute for Disease Prevention, American Health Foundation, Valhalla, N. Y., USA

Contributions to Tobacco & Nicotine Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Phytosterols in Tobacco: Quantitative Analysis and Fate in Tobacco Combustion"}

The influence of tobacco phytosterols (cholesterol, campesterol, stigmasteroI, b-sitosterol) on the chemical composition and biologicaI activity of tobacco...

Phytosterols in Tobacco: Quantitative Analysis and Fate in Tobacco Combustion

Published Online: Aug 14, 2014

Page range: 211 - 218

Received: Feb 26, 1975

DOI: https://doi.org/10.2478/cttr-2013-0382

© Beiträge zur Tabakforschung International

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.