<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Despite a fairly large amount of literature data about the involvement of hydrogen sulfide in physiological and pathophysiological processes, its role in gastrointestinal tract functioning has not been studied sufficiently. This review systematizes and generalizes the mechanisms of H<sub>2</sub>S-associated regulation of gastrointestinal secretion and motility on the basis of literature sources processing and own research results. We analysed world professional literature and sources in Google Scholar, PubMed, MedLine, Embase, Cochrane, and data from more than 50 articles and books on the problem were processed in the article. This review gives a synopsis of the H2S function in the regulation of the secretory and motor-evacuation function, and in stimulating the reparative properties of the digestive tract, and indicates the main mechanisms.</p></abstract>

Despite a fairly large amount of literature data about the involvement of hydrogen sulfide in physiological and pathophysiological processes, its role in gastrointestinal tract functioning has not been studied sufficiently. This review systematizes and generalizes the mechanisms of H2S-associated regulation of gastrointestinal secretion and motility on the basis of literature sources processing and own research results. We analysed world professional literature and sources in Google Scholar, PubMed, MedLine, Embase, Cochrane, and data from more than 50 articles and books on the problem were processed in the article. This review gives a synopsis of the H2S function in the regulation of the secretory and motor-evacuation function, and in stimulating the reparative properties of the digestive tract, and indicates the main mechanisms.

The role of hydrogen sulfide in gastrointestinal tract functioning (review)

National Pirogov Memorial Medical University

Current Issues in Pharmacy and Medical Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"The role of hydrogen sulfide in gastrointestinal tract functioning (review)"}

Despite a fairly large amount of literature data about the involvement of hydrogen sulfide in physiological and pathophysiological processes, its role in...

The role of hydrogen sulfide in gastrointestinal tract functioning (review)

Published Online: Mar 27, 2020

Page range: 45 - 50

Received: Mar 13, 2019

Accepted: Jul 24, 2019

DOI: https://doi.org/10.2478/cipms-2020-0009

Keywords
hydrogen sulfide, gastrointestinal tract, reparative properties, secretory function, motor-evacuation function

© 2020 Natalia Voloshchuk et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

The role of hydrogen sulfide in gastrointestinal tract functioning (review)

Published Online: Mar 27, 2020

Page range: 45 - 50

Received: Mar 13, 2019

Accepted: Jul 24, 2019

DOI: https://doi.org/10.2478/cipms-2020-0009

Keywordshydrogen sulfide, gastrointestinal tract, reparative properties, secretory function, motor-evacuation function

© 2020 Natalia Voloshchuk et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
hydrogen sulfide, gastrointestinal tract, reparative properties, secretory function, motor-evacuation function