<abstract xmlns="http://www.w3.org/1999/xhtml"><p> In this paper we are focused on analysis of hydroxychalcones, i.e. 2’-hydroxychalcone, 3’-hydroxychalcone and 4’-hydroxychalcone, by the Flowing Atmospheric Pressure Afterglow mass spectrometry (FAPA-MS), and on comparison of the obtained data with other classical methods including ESI-MS, APCI, MALDI, and GC/EI-MS. The paper is presenting fragmentation pathways of both positive-, and negative hydroxychalcone ions. Tested compounds were characterized by comparison of the results (signals m/z and relative intensities) from the five mass spectrometry techniques, showing very good utility of FAPA method for fast and easy analysis of the low molecular weight compounds. Moreover, FAPA does not require a time-consuming derivatization, nor search for a suitable solvent or matrix, often incompatible with various ion sources.</p></abstract>

In this paper we are focused on analysis of hydroxychalcones, i.e. 2’-hydroxychalcone, 3’-hydroxychalcone and 4’-hydroxychalcone, by the Flowing Atmospheric Pressure Afterglow mass spectrometry (FAPA-MS), and on comparison of the obtained data with other classical methods including ESI-MS, APCI, MALDI, and GC/EI-MS. The paper is presenting fragmentation pathways of both positive-, and negative hydroxychalcone ions. Tested compounds were characterized by comparison of the results (signals m/z and relative intensities) from the five mass spectrometry techniques, showing very good utility of FAPA method for fast and easy analysis of the low molecular weight compounds. Moreover, FAPA does not require a time-consuming derivatization, nor search for a suitable solvent or matrix, often incompatible with various ion sources.

FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization

AGH University of Science and Technology, Department of Biochemistry and Neurobiology, Faculty of Materials Science and Ceramics, Mickiewicza 30, 30-059 Cracow, Poland

Adam Mickiewicz University in Poznań, Faculty of Chemistry, Umultowska 89b, 61-614 Poznan, Poland

ERTEC-Poland, Rogowska 146/5, 54-440 Wroclaw, Poland

Institute of Forensic Research, Westerplatte 9, 31-033 Cracow, Poland

Centre of Polymer and Carbon Materials, Polish Academy of Sciences, Curie-Sklodowskiej 34, 41-819 Zabrze, Poland

Current Issues in Pharmacy and Medical Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

In this paper we are focused on analysis of hydroxychalcones, i.e. 2’-hydroxychalcone, 3’-hydroxychalcone and 4’-hydroxychalcone, by the Flowing Atmospheric...

FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization

Published Online: May 30, 2014

Page range: 27 - 31

Received: Feb 13, 2014

Accepted: Mar 07, 2014

DOI: https://doi.org/10.2478/cipms-2014-0008

Keywords
FAPA, mass spectrometry, hydroxychalcones

© 2014

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization

Published Online: May 30, 2014

Page range: 27 - 31

Received: Feb 13, 2014

Accepted: Mar 07, 2014

DOI: https://doi.org/10.2478/cipms-2014-0008

KeywordsFAPA, mass spectrometry, hydroxychalcones

© 2014

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
FAPA, mass spectrometry, hydroxychalcones