<abstract xmlns="http://www.w3.org/1999/xhtml">

<italic>Study aim</italic>: The aim of the present study was to determine the effect of 8 days of water-only fasting and physical exercise on somatic variables, lipid profile, insulin resistance and cardiovascular function in middle-aged men.
<italic>Material and methods</italic>: Body weight, body composition, lipid profile, serum concentrations of insulin, glucose, β-hydroxybutyrate (β-HB), heart rate (HR), blood pressure and the homeostasis model assessment of insulin resistance (HOMA-IR) were determined in 16 apparently healthy men at rest and after aerobic exercise. This test procedure was also repeated after 8 days of water-only fasting.
<italic>Results</italic>: Fasting intervention resulted in a reduction in body weight and fat mass (p &lt; 0.001). The simultaneous effect of fasting and exercise resulted in significant changes in lipid profile, carbohydrate metabolism and cardiovascular function. Post hoc analyses showed that the reductions in insulin and glucose concentrations as well as the HOMA-IR index were caused by the fasting, and changes in the lipid profile and cardiovascular function were caused by the exercise test.
<italic>Conclusion</italic>: The combined use of fasting and physical effort resulted in an optimal effect on health indicators of the surveyed men.
</abstract>

Study aim: The aim of the present study was to determine the effect of 8 days of water-only fasting and physical exercise on somatic variables, lipid profile, insulin resistance and cardiovascular function in middle-aged men.
Material and methods: Body weight, body composition, lipid profile, serum concentrations of insulin, glucose, β-hydroxybutyrate (β-HB), heart rate (HR), blood pressure and the homeostasis model assessment of insulin resistance (HOMA-IR) were determined in 16 apparently healthy men at rest and after aerobic exercise. This test procedure was also repeated after 8 days of water-only fasting.
Results: Fasting intervention resulted in a reduction in body weight and fat mass (p < 0.001). The simultaneous effect of fasting and exercise resulted in significant changes in lipid profile, carbohydrate metabolism and cardiovascular function. Post hoc analyses showed that the reductions in insulin and glucose concentrations as well as the HOMA-IR index were caused by the fasting, and changes in the lipid profile and cardiovascular function were caused by the exercise test.
Conclusion: The combined use of fasting and physical effort resulted in an optimal effect on health indicators of the surveyed men.

Effect of 8 days of water-only fasting and vigorous exercise on anthropometric parameters, lipid profile and HOMA-IR in middle-aged men

Department of Bioenergetics and Physiology of Exercise

Department of Biochemistry, Faculty of Medical Science in Zabrze

Department of Biophysics, Faculty of Medical Sciences in Zabrze

Biomedical Human Kinetics

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Study aim: The aim of the present study was to determine the effect of 8 days of water-only fasting and physical exercise on somatic variables, lipid profile,...

Effect of 8 days of water-only fasting and vigorous exercise on anthropometric parameters, lipid profile and HOMA-IR in middle-aged men

Published Online: Dec 07, 2023

Page range: 289 - 297

Received: Aug 14, 2023

Accepted: Oct 17, 2023

DOI: https://doi.org/10.2478/bhk-2023-0035

Keywords
Fasting, Exercise, Anthropometric parameters, Lipid profile, Carbohydrate metabolism, Cardiovascular function

© 2023 Karol Pilis et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Effect of 8 days of water-only fasting and vigorous exercise on anthropometric parameters, lipid profile and HOMA-IR in middle-aged men

Published Online: Dec 07, 2023

Page range: 289 - 297

Received: Aug 14, 2023

Accepted: Oct 17, 2023

DOI: https://doi.org/10.2478/bhk-2023-0035

KeywordsFasting, Exercise, Anthropometric parameters, Lipid profile, Carbohydrate metabolism, Cardiovascular function

© 2023 Karol Pilis et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Fasting, Exercise, Anthropometric parameters, Lipid profile, Carbohydrate metabolism, Cardiovascular function