<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>An investigation was carried out to extract the polyphenols from <italic>Cynodon dactylon</italic> L. by ultrasound-assisted extraction (UAE) and maceration assisted extraction (MAE), and to assess the antioxidant and antimicrobial activities, as well as the evaluation of the cytotoxic effect of ethanolic extracts. The yields of crude extracts were 9.40 % for the MAE extract and 12.52 % for the UAE extract. The results showed that the extract obtained by MAE contains a high level of polyphenols and flavonoids estimated by 42.14 ± 0.75 mg EAG/gE and 23.57 ± 0.78 mg EQ/gE. In contrast, the content of condensed tannins in the extract of UAE (19.34 ± 0.48 mg EC/gE) is higher. The evaluation of the antioxidant activity revealed a considerable antioxidant response, the MAE extract represents the most active extract, with an IC<sub>50</sub> =7.52 ± 0.037 mg/mL for the DPPH test, and 15.83 ± 0.37 mg EAA/gE for the FRAP test. The results of antimicrobial activity showed that all the strains targeted have high susceptibility to the two ethanolic extracts of <italic>Cynodon dactylon</italic> L. The evaluation of cytotoxicity against RBCs was carried, the results shown the non-toxic effect of <italic>C. dactylon</italic> extracts and hence support its ethnomedicinal application.</p>
</abstract>

An investigation was carried out to extract the polyphenols from Cynodon dactylon L. by ultrasound-assisted extraction (UAE) and maceration assisted extraction (MAE), and to assess the antioxidant and antimicrobial activities, as well as the evaluation of the cytotoxic effect of ethanolic extracts. The yields of crude extracts were 9.40 % for the MAE extract and 12.52 % for the UAE extract. The results showed that the extract obtained by MAE contains a high level of polyphenols and flavonoids estimated by 42.14 ± 0.75 mg EAG/gE and 23.57 ± 0.78 mg EQ/gE. In contrast, the content of condensed tannins in the extract of UAE (19.34 ± 0.48 mg EC/gE) is higher. The evaluation of the antioxidant activity revealed a considerable antioxidant response, the MAE extract represents the most active extract, with an IC50 =7.52 ± 0.037 mg/mL for the DPPH test, and 15.83 ± 0.37 mg EAA/gE for the FRAP test. The results of antimicrobial activity showed that all the strains targeted have high susceptibility to the two ethanolic extracts of Cynodon dactylon L. The evaluation of cytotoxicity against RBCs was carried, the results shown the non-toxic effect of C. dactylon extracts and hence support its ethnomedicinal application.

Comparison of ultrasound and maceration methods on antioxidant and antimicrobial efficacy of phenolic compounds extracted from <italic>Cynodon dactylon</italic> L. of Algeria

Department of Cellular and Molecular Biology

Biogeochemistry of Desert Environments laboratory

Ovidius University Annals of Chemistry

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Comparison of ultrasound and maceration methods on antioxidant and antimicrobial efficacy of phenolic compounds extracted from  L. of Algeria

An investigation was carried out to extract the polyphenols from Cynodon dactylon L. by ultrasound-assisted extraction (UAE) and maceration assisted extraction...

Comparison of ultrasound and maceration methods on antioxidant and antimicrobial efficacy of phenolic compounds extracted from Cynodon dactylon L. of Algeria

Published Online: Jul 28, 2022

Page range: 121 - 128

Received: Aug 09, 2021

Accepted: Jul 17, 2022

DOI: https://doi.org/10.2478/auoc-2022-0018

Keywords
phenolic compounds, antioxidant activity, antimicrobial activity, cytotoxicity

© 2022 Mohammed Laid Tlili et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Comparison of ultrasound and maceration methods on antioxidant and antimicrobial efficacy of phenolic compounds extracted from Cynodon dactylon L. of Algeria

Published Online: Jul 28, 2022

Page range: 121 - 128

Received: Aug 09, 2021

Accepted: Jul 17, 2022

DOI: https://doi.org/10.2478/auoc-2022-0018

Keywordsphenolic compounds, antioxidant activity, antimicrobial activity, cytotoxicity

© 2022 Mohammed Laid Tlili et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
phenolic compounds, antioxidant activity, antimicrobial activity, cytotoxicity