<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>A number of nine benzylidene-4-nitroanilines were synthesized by condensation method. The formation of the substituted (<italic>E</italic>)-N-benzylidene-4-nitrobenzenamines has been confirmed from their physical and Ultra-Violet, Infra-Red, NMR spectral data. The evaluation of antimicrobial screening of substituted (<italic>E</italic>)-N-benzylidene-4-nitrobenzenamines was conducted by using standard Bauer-Kirby method. Three gram-positive microbes namely <italic>Bacillus subtilis</italic>, <italic>Micrococcus luteus</italic> and <italic>Staphylococcus aureus</italic>, and two gram-negative microbes, <italic>Escherichia coli</italic> and <italic>Pseudomonas aeruginosa</italic>, were used for the antibacterial evaluation. The antifungal activities against <italic>Aspergillus niger</italic> and <italic>Penicilium scup</italic> fungal species were also performed. A good antibacterial effect has been possessed by some of the substituted (<italic>E</italic>)-N-benzylidene-4-nitrobenzenamines on the microorganisms utilized in the present study</p>
</abstract>

A number of nine benzylidene-4-nitroanilines were synthesized by condensation method. The formation of the substituted (E)-N-benzylidene-4-nitrobenzenamines has been confirmed from their physical and Ultra-Violet, Infra-Red, NMR spectral data. The evaluation of antimicrobial screening of substituted (E)-N-benzylidene-4-nitrobenzenamines was conducted by using standard Bauer-Kirby method. Three gram-positive microbes namely Bacillus subtilis, Micrococcus luteus and Staphylococcus aureus, and two gram-negative microbes, Escherichia coli and Pseudomonas aeruginosa, were used for the antibacterial evaluation. The antifungal activities against Aspergillus niger and Penicilium scup fungal species were also performed. A good antibacterial effect has been possessed by some of the substituted (E)-N-benzylidene-4-nitrobenzenamines on the microorganisms utilized in the present study

Synthesis and pharmacological evaluation of some benzylidene-4-nitroanilines

Ovidius University Annals of Chemistry

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Synthesis and pharmacological evaluation of some benzylidene-4-nitroanilines"}

A number of nine benzylidene-4-nitroanilines were synthesized by condensation method. The formation of the substituted (E)-N-benzylidene-4-nitrobenzenamines...

Synthesis and pharmacological evaluation of some benzylidene-4-nitroanilines

Published Online: Sep 18, 2020

Page range: 55 - 59

Received: Apr 03, 2020

Accepted: Jun 17, 2020

DOI: https://doi.org/10.2478/auoc-2020-0011

Keywords
benzylidene-4-nitroanilines, IR and NMR spectra, antimicrobial activities

© 2020 Ramamurthy Suresh et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Synthesis and pharmacological evaluation of some benzylidene-4-nitroanilines

Published Online: Sep 18, 2020

Page range: 55 - 59

Received: Apr 03, 2020

Accepted: Jun 17, 2020

DOI: https://doi.org/10.2478/auoc-2020-0011

Keywordsbenzylidene-4-nitroanilines, IR and NMR spectra, antimicrobial activities

© 2020 Ramamurthy Suresh et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
benzylidene-4-nitroanilines, IR and NMR spectra, antimicrobial activities