<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Current studies are focused on medicinal plants secondary metabolites as a source of new anticancer agents. The aim of this study was to evaluate in vitro influence of methanolic extracts of Achillea thracica Velen. from natural habitat, in vitro propagated and ex vitro established plants on tumor cells proliferation/viability. All extract tested (50 µg/ml for 24 hours) significantly inhibited SK-HEP-1 cell line proliferation/viability (Р ≤ 0.05). The inhibitory effect of ex vitro established plants was slightly weaker in comparison with A. thracica grown in its natural habitat. So, ex situ conservation of A. thracica enables an opportunity to explore its valuable phytochemicals.</p>
</abstract>

Current studies are focused on medicinal plants secondary metabolites as a source of new anticancer agents. The aim of this study was to evaluate in vitro influence of methanolic extracts of Achillea thracica Velen. from natural habitat, in vitro propagated and ex vitro established plants on tumor cells proliferation/viability. All extract tested (50 µg/ml for 24 hours) significantly inhibited SK-HEP-1 cell line proliferation/viability (Р ≤ 0.05). The inhibitory effect of ex vitro established plants was slightly weaker in comparison with A. thracica grown in its natural habitat. So, ex situ conservation of A. thracica enables an opportunity to explore its valuable phytochemicals.

Anticancer activity of <italic>Achillea thracica</italic> Velen. methanol extracts

Acta Scientifica Naturalis

This work is licensed under the Creative Commons Attribution 3.0 Public License.

Anticancer activity of  Velen. methanol extracts

Current studies are focused on medicinal plants secondary metabolites as a source of new anticancer agents. The aim of this study was to evaluate in vitro...

Anticancer activity of Achillea thracica Velen. methanol extracts

Published Online: Dec 15, 2023

Page range: 21 - 24

DOI: https://doi.org/10.2478/asn-2023-0020

Keywords
Velen., methanolic extracts, in vitro cytotoxicity

© 2023 Vanya Koleva et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 3.0 Public License.

Anticancer activity of Achillea thracica Velen. methanol extracts

Published Online: Dec 15, 2023

Page range: 21 - 24

DOI: https://doi.org/10.2478/asn-2023-0020

KeywordsVelen., methanolic extracts, in vitro cytotoxicity

© 2023 Vanya Koleva et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 3.0 Public License.

Keywords
Velen., methanolic extracts, in vitro cytotoxicity