<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The aim of this work was to establish the antioxidant and antimicrobial activity of hydro-alcoholic and aqueous extracts prepared from the leaves of Globularia alypum L. The quantitative estimation of total polyphenols (by the Folin-Ciocalteu method) and total flavonoids (by the method of aluminium trichloride) showed that the aqueous and ethyl acetate extracts had the highest content of phenolic and flavonoid compounds. Moreover, the results of antioxidant power assessed by both method DPPH and phosphomolybdenum indicated that leaves extracts of G. alypum expressed a considerable activity. The evaluation of the antimicrobial effects, using the disc diffusion method from antibacterial screening and the direct contact method from the antifungal activity, indicated strong antibacterial and antifungal activity.</p></abstract>

The aim of this work was to establish the antioxidant and antimicrobial activity of hydro-alcoholic and aqueous extracts prepared from the leaves of Globularia alypum L. The quantitative estimation of total polyphenols (by the Folin-Ciocalteu method) and total flavonoids (by the method of aluminium trichloride) showed that the aqueous and ethyl acetate extracts had the highest content of phenolic and flavonoid compounds. Moreover, the results of antioxidant power assessed by both method DPPH and phosphomolybdenum indicated that leaves extracts of G. alypum expressed a considerable activity. The evaluation of the antimicrobial effects, using the disc diffusion method from antibacterial screening and the direct contact method from the antifungal activity, indicated strong antibacterial and antifungal activity.

<italic>In vitro</italic> investigation of the antioxidant and antimicrobial effects of hydro-alcoholic and aqueous extracts of <italic>Globularia alypum</italic> L.

Département de Biologie, Laboratoire Biomolécules Végétales et Amélioration des Plantes

Département des Sciences de la Nature et de la Vie, Laboratoire Biomolécules Végétales et Amélioration des Plantes

Acta Scientifica Naturalis

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

 investigation of the antioxidant and antimicrobial effects of hydro-alcoholic and aqueous extracts of  L.

The aim of this work was to establish the antioxidant and antimicrobial activity of hydro-alcoholic and aqueous extracts prepared from the leaves of Globularia...

In vitro investigation of the antioxidant and antimicrobial effects of hydro-alcoholic and aqueous extracts of Globularia alypum L.

Published Online: Apr 18, 2020

Page range: 46 - 58

DOI: https://doi.org/10.2478/asn-2020-0006

Keywords
L., phenolic extracts, antimicrobial activity, antioxidant activity

© 2020 Lamia Kraza et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

In vitro investigation of the antioxidant and antimicrobial effects of hydro-alcoholic and aqueous extracts of Globularia alypum L.

Published Online: Apr 18, 2020

Page range: 46 - 58

DOI: https://doi.org/10.2478/asn-2020-0006

KeywordsL., phenolic extracts, antimicrobial activity, antioxidant activity

© 2020 Lamia Kraza et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
L., phenolic extracts, antimicrobial activity, antioxidant activity