<abstract xmlns="http://www.w3.org/1999/xhtml">

Lichen sclerosus (LS) is a chronic mucocutaneous sclerosis most commonly affecting the genital area, although extragenital localizations have also been described1, with unknown pathogenesis.
Our study aims to analyze the morphopathological aspects of LS through the prism of polarized microscopy and with the help of histochemical information provided by special Van Gieson stain for elastic tissue and Picro-Sirius Red special stain.
Picro-Sirius Red staining allows observation of the type of collagen synthesized in pathological conditions such as LS, as well as the appearance of mature hyalinization through loss of elastic tissue, and also the disappearing of piloerectile muscles.
</abstract>

Lichen sclerosus (LS) is a chronic mucocutaneous sclerosis most commonly affecting the genital area, although extragenital localizations have also been described1, with unknown pathogenesis.
Our study aims to analyze the morphopathological aspects of LS through the prism of polarized microscopy and with the help of histochemical information provided by special Van Gieson stain for elastic tissue and Picro-Sirius Red special stain.
Picro-Sirius Red staining allows observation of the type of collagen synthesized in pathological conditions such as LS, as well as the appearance of mature hyalinization through loss of elastic tissue, and also the disappearing of piloerectile muscles.

Polarized Microscopy Study of 10 Cases of Lichen Sclerosus Using Picro-Sirius Red Stain

ARS Medica Tomitana

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Lichen sclerosus (LS) is a chronic mucocutaneous sclerosis most commonly affecting the genital area, although extragenital localizations have also been...

Polarized Microscopy Study of 10 Cases of Lichen Sclerosus Using Picro-Sirius Red Stain

Published Online: Aug 17, 2022

Page range: 27 - 30

DOI: https://doi.org/10.2478/arsm-2021-0006

Keywords
Lichen sclerosus, collagen, polarized microscopy, Picro-Sirius Red

© 2021 Mocanu Liliana et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Polarized Microscopy Study of 10 Cases of Lichen Sclerosus Using Picro-Sirius Red Stain

Published Online: Aug 17, 2022

Page range: 27 - 30

DOI: https://doi.org/10.2478/arsm-2021-0006

KeywordsLichen sclerosus, collagen, polarized microscopy, Picro-Sirius Red

© 2021 Mocanu Liliana et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Lichen sclerosus, collagen, polarized microscopy, Picro-Sirius Red