<abstract xmlns="http://www.w3.org/1999/xhtml">
<p>A newly characterized actinobacterial strain, designated B20, displayed remarkable tolerance to extreme pH and NaCl conditions, while showcasing a diversity in carbon source utilization. Phylogenetic analysis confirmed its taxonomic assignment within the genus <italic>Nocardiopsis</italic>. However, several physiological features were found to differentiate B20 from its most closely related <italic>Nocardiopsis</italic> species. Notably, <italic>Nocardiopsis</italic> sp. B20 demonstrated potent and selective antifungal activity against various micro-fungi, suggesting its potential as a valuable source for targeted antifungal compounds. Ethyl acetate extract contains a bioactive compound, B20-1, displaying antifungal properties. Chemical revelations indicated the presence of sugars and polycyclic aromatic hydrocarbons (PAHs) in B20-1 compound. The discovery of antifungal PAHs derived from natural sources presents promising opportunity for addressing fungal infections while mitigating environmental concerns and resistance risks associated with synthetic fungicides. However, further research is warranted to evaluate efficacy, assess ecological impacts, and explore potential applications across diverse industries. </p>
</abstract>

A newly characterized actinobacterial strain, designated B20, displayed remarkable tolerance to extreme pH and NaCl conditions, while showcasing a diversity in carbon source utilization. Phylogenetic analysis confirmed its taxonomic assignment within the genus Nocardiopsis. However, several physiological features were found to differentiate B20 from its most closely related Nocardiopsis species. Notably, Nocardiopsis sp. B20 demonstrated potent and selective antifungal activity against various micro-fungi, suggesting its potential as a valuable source for targeted antifungal compounds. Ethyl acetate extract contains a bioactive compound, B20-1, displaying antifungal properties. Chemical revelations indicated the presence of sugars and polycyclic aromatic hydrocarbons (PAHs) in B20-1 compound. The discovery of antifungal PAHs derived from natural sources presents promising opportunity for addressing fungal infections while mitigating environmental concerns and resistance risks associated with synthetic fungicides. However, further research is warranted to evaluate efficacy, assess ecological impacts, and explore potential applications across diverse industries.

New Alkali-tolerant and Halo-tolerant <italic>Nocardiopsis</italic> Strain B20 from Algerian Saharan Soil: Isolation, Taxonomy, and Antifungal Activity 

Laboratoire de Biologie des Systèmes Microbiens (LBSM), Ecole Normale Supérieure de Kouba

Laboratoire de Valorisation et Conservation des Écosystèmes Arides (LVCEA)

Faculté des Sciences de la Nature et de la Vie et Sciences de la Terre, Université de Ghardaïa

Département de Biologie, Faculté des Sciences et Technologie

Advanced Research in Life Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

New Alkali-tolerant and Halo-tolerant  Strain B20 from Algerian Saharan Soil: Isolation, Taxonomy, and Antifungal Activity 

A newly characterized actinobacterial strain, designated B20, displayed remarkable tolerance to extreme pH and NaCl conditions, while showcasing a diversity in...

New Alkali-tolerant and Halo-tolerant Nocardiopsis Strain B20 from Algerian Saharan Soil: Isolation, Taxonomy, and Antifungal Activity

Published Online: Sep 13, 2023

Page range: 73 - 82

Received: May 01, 2023

Accepted: Aug 01, 2023

DOI: https://doi.org/10.2478/arls-2023-0009

Keywords
alkali-tolerance, halo-tolerance, Saharan soil, taxonomy, antifungal activity, polycyclic aromatic hydrocarbons

© 2023 Khaoula Bouznada et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

New Alkali-tolerant and Halo-tolerant Nocardiopsis Strain B20 from Algerian Saharan Soil: Isolation, Taxonomy, and Antifungal Activity

Published Online: Sep 13, 2023

Page range: 73 - 82

Received: May 01, 2023

Accepted: Aug 01, 2023

DOI: https://doi.org/10.2478/arls-2023-0009

Keywordsalkali-tolerance, halo-tolerance, Saharan soil, taxonomy, antifungal activity, polycyclic aromatic hydrocarbons

© 2023 Khaoula Bouznada et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
alkali-tolerance, halo-tolerance, Saharan soil, taxonomy, antifungal activity, polycyclic aromatic hydrocarbons