<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The present study was performed to investigate the effects of dietary yeast β-1,3/1,6-D-glucans after 15-, 30-, and 45-day feeding periods on the development of oxidative stress, antioxidant defenses, and lysosomal functioning in gills and hepatic tissue of rainbow trout, <italic>Oncorhynchus mykiss</italic> (Walbaum). The fish were fed a control diet or an experimental diet containing the supplement Yestimun<sup>®</sup> at a dose of 1% in the basal feed (with 85% content of β-1,3/1,6-glucans). On days 15, 30, and 45 of the experiment, the following were analyzed in gills and hepatic tissue: oxidative stress biomarkers (2-thiobarbituric-acid-reacting substances [TBARS]); aldehydic and ketonic derivatives of oxidatively modified proteins; activities of superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), and glutathione peroxidase (GPx); total antioxidant capacity (TAC); activities of lysosomal enzymes (alanyl aminopeptidase [AAP], leucyl aminopeptidase [LAP], acid phosphatase [AcP], β-N-acetylglucosaminidase [NAG]). The dietary β-glucans stimulated CAT, GPx, LAP, and AcP activities in gills and hepatic tissue compared to the control group; however, the opposite trend was observed in TAC levels in gills on days 30 and 45. The present study suggests that β-glucans can enhance immune response, antioxidant capacity, and lysosomal functioning effectively in rainbow trout.</p>
</abstract>

The present study was performed to investigate the effects of dietary yeast β-1,3/1,6-D-glucans after 15-, 30-, and 45-day feeding periods on the development of oxidative stress, antioxidant defenses, and lysosomal functioning in gills and hepatic tissue of rainbow trout, Oncorhynchus mykiss (Walbaum). The fish were fed a control diet or an experimental diet containing the supplement Yestimun® at a dose of 1% in the basal feed (with 85% content of β-1,3/1,6-glucans). On days 15, 30, and 45 of the experiment, the following were analyzed in gills and hepatic tissue: oxidative stress biomarkers (2-thiobarbituric-acid-reacting substances [TBARS]); aldehydic and ketonic derivatives of oxidatively modified proteins; activities of superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), and glutathione peroxidase (GPx); total antioxidant capacity (TAC); activities of lysosomal enzymes (alanyl aminopeptidase [AAP], leucyl aminopeptidase [LAP], acid phosphatase [AcP], β-N-acetylglucosaminidase [NAG]). The dietary β-glucans stimulated CAT, GPx, LAP, and AcP activities in gills and hepatic tissue compared to the control group; however, the opposite trend was observed in TAC levels in gills on days 30 and 45. The present study suggests that β-glucans can enhance immune response, antioxidant capacity, and lysosomal functioning effectively in rainbow trout.

Modulation of oxidative stress biomarkers and lysosomal functioning in gills and liver of rainbow trout (<italic>Oncorhynchus mykiss</italic> Walbaum) fed a diet supplemented with yeast β-glucans

National Inland Fisheries Research Institute

Fisheries & Aquatic Life

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Modulation of oxidative stress biomarkers and lysosomal functioning in gills and liver of rainbow trout ( Walbaum) fed a diet supplemented with yeast β-glucans

The present study was performed to investigate the effects of dietary yeast β-1,3/1,6-D-glucans after 15-, 30-, and 45-day feeding periods on the development...

Modulation of oxidative stress biomarkers and lysosomal functioning in gills and liver of rainbow trout (Oncorhynchus mykiss Walbaum) fed a diet supplemented with yeast β-glucans

Published Online: Jun 07, 2024

Page range: 44 - 62

Received: Mar 20, 2023

Accepted: Mar 29, 2024

DOI: https://doi.org/10.2478/aopf-2024-0005

Keywords
yeast β-glucans, oxidative stress, rainbow trout, gills, liver

© 2024 Kurhaluk et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Modulation of oxidative stress biomarkers and lysosomal functioning in gills and liver of rainbow trout (Oncorhynchus mykiss Walbaum) fed a diet supplemented with yeast β-glucans

Published Online: Jun 07, 2024

Page range: 44 - 62

Received: Mar 20, 2023

Accepted: Mar 29, 2024

DOI: https://doi.org/10.2478/aopf-2024-0005

Keywordsyeast β-glucans, oxidative stress, rainbow trout, gills, liver

© 2024 Kurhaluk et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
yeast β-glucans, oxidative stress, rainbow trout, gills, liver