<abstract xmlns="http://www.w3.org/1999/xhtml">
Bacterial diseases are one of the major factors hampering aquaculture sustainability. Antibiotics are used widely to treat or prevent infectious bacterial diseases in aquaculture. However, because of growing problems of antibiotic resistance caused by the imprudent use of antibiotics, sourcing environmentally benign alternatives, such as herbal/medicinal plants, is now the focus of many researchers. Hence, in this study, a minimum inhibitory concentration (MIC) test with broth microdilution was performed to determine the in vitro antibacterial activity of an aqueous methanolic extract of cultivated Caucasian whortleberry (<italic>Vaccinium arctostaphylos </italic>L.) against various fish pathogens, i.e., <italic>Yersinia ruckeri</italic>, <italic>Pseudomonas putida</italic>, <italic>P. luteola</italic>, <italic>Aeromonas salmonicida</italic>, <italic>A. hydrophila</italic>, and <italic>A. sobria</italic>. The results revealed that the MIC values of the aqueous methanolic extract against <italic>Y. ruckeri</italic>, <italic>P. putida</italic>, <italic>P. luteola</italic>, <italic>A. salmonicida</italic>, and <italic>A. hydrophila </italic>were 8.75 mg mL−1, while against <italic>A. sobria </italic>it was 2.19 mg mL−1. This study indicated that the medicinal plant <italic>V. arctostaphylos </italic>L. can potentially be used against all the fish pathogens tested thanks to its various important bioactive compounds. However, to assess the potential of this plant, further in vivo studies should be carried out.
</abstract>

Bacterial diseases are one of the major factors hampering aquaculture sustainability. Antibiotics are used widely to treat or prevent infectious bacterial diseases in aquaculture. However, because of growing problems of antibiotic resistance caused by the imprudent use of antibiotics, sourcing environmentally benign alternatives, such as herbal/medicinal plants, is now the focus of many researchers. Hence, in this study, a minimum inhibitory concentration (MIC) test with broth microdilution was performed to determine the in vitro antibacterial activity of an aqueous methanolic extract of cultivated Caucasian whortleberry (Vaccinium arctostaphylos L.) against various fish pathogens, i.e., Yersinia ruckeri, Pseudomonas putida, P. luteola, Aeromonas salmonicida, A. hydrophila, and A. sobria. The results revealed that the MIC values of the aqueous methanolic extract against Y. ruckeri, P. putida, P. luteola, A. salmonicida, and A. hydrophila were 8.75 mg mL−1, while against A. sobria it was 2.19 mg mL−1. This study indicated that the medicinal plant V. arctostaphylos L. can potentially be used against all the fish pathogens tested thanks to its various important bioactive compounds. However, to assess the potential of this plant, further in vivo studies should be carried out.

Evaluation of the antibacterial activity of cultivated Caucasian whortleberry (<italic>Vaccinium arctostaphylos </italic>L.) against fish pathogens

Mindanao State University-Tawi-Tawi College of Technology and Oceanography

Fisheries & Aquatic Life

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Evaluation of the antibacterial activity of cultivated Caucasian whortleberry (L.) against fish pathogens

Bacterial diseases are one of the major factors hampering aquaculture sustainability. Antibiotics are used widely to treat or prevent infectious bacterial...

Evaluation of the antibacterial activity of cultivated Caucasian whortleberry (Vaccinium arctostaphylos L.) against fish pathogens

Published Online: Sep 06, 2023

Page range: 79 - 86

Received: Dec 13, 2022

Accepted: Jun 18, 2023

DOI: https://doi.org/10.2478/aopf-2023-0009

Keywords
Bioactive compounds, Bacterial diseases, Fish health management, Medicinal plant, Minimum inhibitory concentration

© 2023 Ertugrul Terzi et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Evaluation of the antibacterial activity of cultivated Caucasian whortleberry (Vaccinium arctostaphylos L.) against fish pathogens

Published Online: Sep 06, 2023

Page range: 79 - 86

Received: Dec 13, 2022

Accepted: Jun 18, 2023

DOI: https://doi.org/10.2478/aopf-2023-0009

KeywordsBioactive compounds, Bacterial diseases, Fish health management, Medicinal plant, Minimum inhibitory concentration

© 2023 Ertugrul Terzi et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
Bioactive compounds, Bacterial diseases, Fish health management, Medicinal plant, Minimum inhibitory concentration