<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The current work aimed to find substitutes for antibiotics because of the side effects of antibacterial agents and the expansion of bacterial resistance to these agents. The scope of this study was to evaluate the antibacterial activity of gold and silver nanoparticles (AuNPs and AgNPs) against selected animal pathogens (<italic>Staphylococcus aureus</italic>, <italic>Klebsiella pneumonia</italic>, <italic>Streptococcus pneumoniae</italic>, <italic>Escherichia coli</italic>, <italic>Bacillus abortus</italic> and <italic>Mycobacterium bovis</italic>). The synthesized nanoparticles were distinguished by scanning electron microscopy (SEM) analysis and tested for antibacterial activity with the broth microdilution method, well diffusion assay, and minimum bactericidal concentration procedure. Results showed that both AuNPs and AgNPs displayed good antibacterial activity against all tested bacteria. The strongest antibacterial action of AgNPS (18 mm) was against <italic>E. coli</italic>. AuNPs displayed good antibacterial activity against <italic>S. aureus</italic> and <italic>B. bovis</italic> with a suppression area of 14 mm. Therefore, it is suggested that AgNPs and AuNPs could be effectively used against animal pathogens and may contribute to reducing antibiotic resistance. However, there is a need for further research on the <italic>in vivo</italic> toxicity and mechanisms of action of AuNPs and AgNPs.</p>
</abstract>

The current work aimed to find substitutes for antibiotics because of the side effects of antibacterial agents and the expansion of bacterial resistance to these agents. The scope of this study was to evaluate the antibacterial activity of gold and silver nanoparticles (AuNPs and AgNPs) against selected animal pathogens (Staphylococcus aureus, Klebsiella pneumonia, Streptococcus pneumoniae, Escherichia coli, Bacillus abortus and Mycobacterium bovis). The synthesized nanoparticles were distinguished by scanning electron microscopy (SEM) analysis and tested for antibacterial activity with the broth microdilution method, well diffusion assay, and minimum bactericidal concentration procedure. Results showed that both AuNPs and AgNPs displayed good antibacterial activity against all tested bacteria. The strongest antibacterial action of AgNPS (18 mm) was against E. coli. AuNPs displayed good antibacterial activity against S. aureus and B. bovis with a suppression area of 14 mm. Therefore, it is suggested that AgNPs and AuNPs could be effectively used against animal pathogens and may contribute to reducing antibiotic resistance. However, there is a need for further research on the in vivo toxicity and mechanisms of action of AuNPs and AgNPs.

Antibacterial activity of metallic-core gold and silver nanoparticles against some animal pathogens

Eskil Vocational School, Aksaray University

Department of Biochemistry, Faculty of Science

The University of Mashreq and UCSI University

Department of Biotechnology, Faculty of Science

Annals of Animal Science

This work is licensed under the Creative Commons Attribution 4.0 International License.

The current work aimed to find substitutes for antibiotics because of the side effects of antibacterial agents and the expansion of bacterial resistance to...

Antibacterial activity of metallic-core gold and silver nanoparticles against some animal pathogens

Published Online: May 03, 2023

Page range: 473 - 479

Received: Dec 17, 2022

Accepted: Jan 16, 2023

DOI: https://doi.org/10.2478/aoas-2023-0008

Keywords
animal pathogenic microorganisms, antibacterial activity, green synthesis, silver and gold nanoparticles

© 2023 Adil Aksoy et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Antibacterial activity of metallic-core gold and silver nanoparticles against some animal pathogens

Published Online: May 03, 2023

Page range: 473 - 479

Received: Dec 17, 2022

Accepted: Jan 16, 2023

DOI: https://doi.org/10.2478/aoas-2023-0008

Keywordsanimal pathogenic microorganisms, antibacterial activity, green synthesis, silver and gold nanoparticles

© 2023 Adil Aksoy et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
animal pathogenic microorganisms, antibacterial activity, green synthesis, silver and gold nanoparticles