<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Health of the intestine is one of the main reasons that affects the bird’s performance, and thus the economic yield in the poultry sector. Various studies have examined how to improve the intestinal health using dietary supplements, including organic acids such as sodium butyrate (SB). The efficacy of the dietary supplementation in poultry is often assessed using an important parameter such as intestinal integrity, which is often assessed as a measure of high villus height and the ratio of villus height to crypt depth, or count of goblet cell numbers. In broilers, the villus length and width were increased by the addition of dietary SB. Since, at day 21 and 42, the villus length was increased by 55 and 27%, and 39 and 18% for birds fed 0.5 and 1 g/kg, respectively, compared with the control diet. Furthermore, SB plays an important role in development of poultry intestinal epithelium. It can be employed by the intestinal epithelial cells as an energy source to stimulate their differentiation and proliferation, and to improve intestinal barrier function. SB is effective against acid intolerant species such as <italic>Salmonella, Clostridium perfringens</italic> and <italic>E. coli</italic>. In addition, use of butyric acid at 0.6% reduced the pH of gastrointestinal segments. For this, SB could be a potential alternative in maintaining the health of gastrointestinal tract and improving the productive performance of poultry. This review refers to the expanding horizons in the research on SB supplementation in poultry health and nutrition.</p></abstract>

Health of the intestine is one of the main reasons that affects the bird’s performance, and thus the economic yield in the poultry sector. Various studies have examined how to improve the intestinal health using dietary supplements, including organic acids such as sodium butyrate (SB). The efficacy of the dietary supplementation in poultry is often assessed using an important parameter such as intestinal integrity, which is often assessed as a measure of high villus height and the ratio of villus height to crypt depth, or count of goblet cell numbers. In broilers, the villus length and width were increased by the addition of dietary SB. Since, at day 21 and 42, the villus length was increased by 55 and 27%, and 39 and 18% for birds fed 0.5 and 1 g/kg, respectively, compared with the control diet. Furthermore, SB plays an important role in development of poultry intestinal epithelium. It can be employed by the intestinal epithelial cells as an energy source to stimulate their differentiation and proliferation, and to improve intestinal barrier function. SB is effective against acid intolerant species such as Salmonella, Clostridium perfringens and E. coli. In addition, use of butyric acid at 0.6% reduced the pH of gastrointestinal segments. For this, SB could be a potential alternative in maintaining the health of gastrointestinal tract and improving the productive performance of poultry. This review refers to the expanding horizons in the research on SB supplementation in poultry health and nutrition.

Effect of Sodium Butyrate on Intestinal Health of Poultry – A Review

Poultry Production Department, Faculty of Agriculture

Department of Poultry, Faculty of Agriculture

Animal and Poultry Production Department, Faculty of Agriculture

Animal Production Research Institute, Agricultural Research Center, Ministry of Agriculture

Forensic Medicine and Toxicology Department, Veterinary Medicine Faculty

Annals of Animal Science

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Effect of Sodium Butyrate on Intestinal Health of Poultry \u2013 A Review"}

Health of the intestine is one of the main reasons that affects the bird’s performance, and thus the economic yield in the poultry sector. Various studies have...

Effect of Sodium Butyrate on Intestinal Health of Poultry – A Review

Published Online: Jan 28, 2020

Page range: 29 - 41

Received: Jun 27, 2019

Accepted: Oct 24, 2019

DOI: https://doi.org/10.2478/aoas-2019-0077

Keywords
poultry, organic acid, mucosa, gut, antimicrobial activity

© 2020 Shaaban S. Elnesr et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Effect of Sodium Butyrate on Intestinal Health of Poultry – A Review

Published Online: Jan 28, 2020

Page range: 29 - 41

Received: Jun 27, 2019

Accepted: Oct 24, 2019

DOI: https://doi.org/10.2478/aoas-2019-0077

Keywordspoultry, organic acid, mucosa, gut, antimicrobial activity

© 2020 Shaaban S. Elnesr et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
poultry, organic acid, mucosa, gut, antimicrobial activity