<abstract xmlns="http://www.w3.org/1999/xhtml">

<bold>Objective</bold>: To investigate the association between testosterone deficiency and depressive and/or anxiety symptoms.
<bold>Methods</bold>: A cross-sectional study was conducted at the urology outpatient clinic from Ludus County Hospital. A set of validated questionnaires ((International Prostate Symptoms Score (IPSS), Depression Anxiety and Stress Scale (DASS-21), Zung Self-rating Depression Scale (Zung SDS)) were self-administrated. Inclusion criteria: age > 40 years. Exclusion criteria: any relevant psychiatric, cardiovascular, or cancer comorbidity. Statistical analyzes were performed using the statistical software Statistical Package for Social Sciences (SPSS, version 23, Chicago, IL, USA).
<bold>Results</bold>: From the total of 55 participants included in the study, 23 (41.8%) had testosterone deficiency. Most were from the 60-69 years decade, 23 participants (41.8%), and the mean age was 59.3 (SD 9.03) years. Eleven (20%) patients had depressive symptoms according to the depression subscale, of these, 7 had mild symptoms and 4 according to Zung SDS. Testosterone deficiency was associated with an increased DASS-21 global score, p=0.021, and depression score, p=0.047.
<bold>Conclusions</bold>: Patients with testosterone deficiency are presenting symptoms of depression. Therefore, these patients need a multi-disciplinary approach that should include a psychological evaluation before making a further management decision.
</abstract>

Objective: To investigate the association between testosterone deficiency and depressive and/or anxiety symptoms.
Methods: A cross-sectional study was conducted at the urology outpatient clinic from Ludus County Hospital. A set of validated questionnaires ((International Prostate Symptoms Score (IPSS), Depression Anxiety and Stress Scale (DASS-21), Zung Self-rating Depression Scale (Zung SDS)) were self-administrated. Inclusion criteria: age > 40 years. Exclusion criteria: any relevant psychiatric, cardiovascular, or cancer comorbidity. Statistical analyzes were performed using the statistical software Statistical Package for Social Sciences (SPSS, version 23, Chicago, IL, USA).
Results: From the total of 55 participants included in the study, 23 (41.8%) had testosterone deficiency. Most were from the 60-69 years decade, 23 participants (41.8%), and the mean age was 59.3 (SD 9.03) years. Eleven (20%) patients had depressive symptoms according to the depression subscale, of these, 7 had mild symptoms and 4 according to Zung SDS. Testosterone deficiency was associated with an increased DASS-21 global score, p=0.021, and depression score, p=0.047.
Conclusions: Patients with testosterone deficiency are presenting symptoms of depression. Therefore, these patients need a multi-disciplinary approach that should include a psychological evaluation before making a further management decision.

Testosterone deficiency is associated with clinically relevant depression symptoms

IOSUD, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures

George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution 4.0 International License.

Objective: To investigate the association between testosterone deficiency and depressive and/or anxiety symptoms.
Methods: A cross-sectional study was...

Testosterone deficiency is associated with clinically relevant depression symptoms

Published Online: Mar 29, 2023

Page range: 50 - 54

Received: Oct 25, 2022

Accepted: Feb 09, 2023

DOI: https://doi.org/10.2478/amma-2023-0008

Keywords
testosterone deficiency, depression, anxiety, stress

© 2023 Liliana Vartolomei et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Testosterone deficiency is associated with clinically relevant depression symptoms

Published Online: Mar 29, 2023

Page range: 50 - 54

Received: Oct 25, 2022

Accepted: Feb 09, 2023

DOI: https://doi.org/10.2478/amma-2023-0008

Keywordstestosterone deficiency, depression, anxiety, stress

© 2023 Liliana Vartolomei et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
testosterone deficiency, depression, anxiety, stress