<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Bronchopulmonary cancer represents the neoplasms associated with the highest mortality rate, despite diagnostic and therapeutic advances in recent decades. Early diagnosis is often difficult due to the paucity of symptoms or superinfections. Screening subjects at risk of developing lung cancer include clinical, bacteriological, inflammatory status, and genetic profile assessment. The personal microbiome has an essential role in the physiology of the human body. The gut-lung axis plays an essential role in carcinogenesis, being involved in various pathways. The lung microbiome can contribute to the development of lung cancer either directly by acting on tumor cells or indirectly by modulating the tumor-associated immune response. The gut microbiome can directly affect the response to immunotherapy in patients with non-small cell lung cancer.</p>
</abstract>

Bronchopulmonary cancer represents the neoplasms associated with the highest mortality rate, despite diagnostic and therapeutic advances in recent decades. Early diagnosis is often difficult due to the paucity of symptoms or superinfections. Screening subjects at risk of developing lung cancer include clinical, bacteriological, inflammatory status, and genetic profile assessment. The personal microbiome has an essential role in the physiology of the human body. The gut-lung axis plays an essential role in carcinogenesis, being involved in various pathways. The lung microbiome can contribute to the development of lung cancer either directly by acting on tumor cells or indirectly by modulating the tumor-associated immune response. The gut microbiome can directly affect the response to immunotherapy in patients with non-small cell lung cancer.

Is the pulmonary microbiome involved in lung cancer pathophysiology?

George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures

Department of Anesthesia and Intensive Care

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Is the pulmonary microbiome involved in lung cancer pathophysiology?"}

Bronchopulmonary cancer represents the neoplasms associated with the highest mortality rate, despite diagnostic and therapeutic advances in recent decades....

Is the pulmonary microbiome involved in lung cancer pathophysiology?

Published Online: Oct 13, 2022

Page range: 99 - 102

Received: Aug 06, 2022

Accepted: Sep 02, 2022

DOI: https://doi.org/10.2478/amma-2022-0021

Keywords
microbiome, lung cancer, microbiome, genetic alterations

© 2022 Corina Eugenia Budin et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Is the pulmonary microbiome involved in lung cancer pathophysiology?

Published Online: Oct 13, 2022

Page range: 99 - 102

Received: Aug 06, 2022

Accepted: Sep 02, 2022

DOI: https://doi.org/10.2478/amma-2022-0021

Keywordsmicrobiome, lung cancer, microbiome, genetic alterations

© 2022 Corina Eugenia Budin et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
microbiome, lung cancer, microbiome, genetic alterations