<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Introduction</bold>: The prevalence of schizophrenia in the general population is about 0.3% -0.7% Pathological use of substances such as cocaine, alcohol, amphetamines and nicotine are common in schizophrenia with a lifetime prevalence of 80%. They tend to isolate themselves in an inner world, thus being prone to substance abuse. The most commonly used substances are: alcohol, nicotine, cocaine, amphetamines, hallucinogens and cannabis.<bold>Method</bold>: We conducted a retrospective, descriptive-analytical study on a group of 139 patients with a positive diagnosis of schizophrenia from the Psychiatry Clinic I of the Mureș County Clinical Hospital hospitalized between 01.01.2018-31.12.2019. The clinical and paraclinical data used were processed from observation sheets in the clinic archive. These were introduced and analyzed in the Microsoft Excel 2016 program, and the statistical test used was Chi Square in the Graph-Pad statistical analysis program.<bold>Results</bold>: Most patients with schizophrenia have a schizoid (41%) and paranoid (32%) personality. Other types are: organic 25% (unstable and impulsive) and obsessive anxiety 2%. Due to the evolution of diseases, patients end up consuming psychoactive substances, tobacco and alcohol. A percentage of 48% of patients were tobacco consumers, 37% were alcohol consumers and 15% consumed psychoactive substances. Tobacco use is not a statistically significant factor in the recurrence of the disease.<bold>Conclusions</bold>: Alcohol, tobacco and psychoactive substances are an important risk factor in the unfavorable evolution of the disease, most hospitalized patients are in the age group 50-59 years.</abstract>

Introduction: The prevalence of schizophrenia in the general population is about 0.3% -0.7% Pathological use of substances such as cocaine, alcohol, amphetamines and nicotine are common in schizophrenia with a lifetime prevalence of 80%. They tend to isolate themselves in an inner world, thus being prone to substance abuse. The most commonly used substances are: alcohol, nicotine, cocaine, amphetamines, hallucinogens and cannabis.Method: We conducted a retrospective, descriptive-analytical study on a group of 139 patients with a positive diagnosis of schizophrenia from the Psychiatry Clinic I of the Mureș County Clinical Hospital hospitalized between 01.01.2018-31.12.2019. The clinical and paraclinical data used were processed from observation sheets in the clinic archive. These were introduced and analyzed in the Microsoft Excel 2016 program, and the statistical test used was Chi Square in the Graph-Pad statistical analysis program.Results: Most patients with schizophrenia have a schizoid (41%) and paranoid (32%) personality. Other types are: organic 25% (unstable and impulsive) and obsessive anxiety 2%. Due to the evolution of diseases, patients end up consuming psychoactive substances, tobacco and alcohol. A percentage of 48% of patients were tobacco consumers, 37% were alcohol consumers and 15% consumed psychoactive substances. Tobacco use is not a statistically significant factor in the recurrence of the disease.Conclusions: Alcohol, tobacco and psychoactive substances are an important risk factor in the unfavorable evolution of the disease, most hospitalized patients are in the age group 50-59 years.

Clinical Evolution of Patients with Schizophrenia Associated with Addictive Disorders

Department of Medical Ethics and Socio-Human Sciences

George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution 4.0 International License.

Introduction: The prevalence of schizophrenia in the general population is about 0.3% -0.7% Pathological use of substances such as cocaine, alcohol,...

Clinical Evolution of Patients with Schizophrenia Associated with Addictive Disorders

Published Online: Dec 31, 2020

Page range: 152 - 154

Received: Oct 30, 2020

Accepted: Nov 24, 2020

DOI: https://doi.org/10.2478/amma-2020-0033

Keywords
schizophrenia, addiction, psychoactive substances, personality, alcoholism

© 2020 Andreea Salcudean et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Clinical Evolution of Patients with Schizophrenia Associated with Addictive Disorders

Published Online: Dec 31, 2020

Page range: 152 - 154

Received: Oct 30, 2020

Accepted: Nov 24, 2020

DOI: https://doi.org/10.2478/amma-2020-0033

Keywordsschizophrenia, addiction, psychoactive substances, personality, alcoholism

© 2020 Andreea Salcudean et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
schizophrenia, addiction, psychoactive substances, personality, alcoholism